Abstract:
:This study identified the brain activations associated with auditory vigilance tasks, using functional magnetic resonance imaging. We created auditory continuous performance tests (CPTs) in which a demanding task (working memory task) was made more difficult than a simple vigilance task by increasing working memory and interference filtering demands. Two cohorts of normal male controls performed significantly worse on the working memory CPT than on the vigilance task. Compared to the vigilance task, performance of the working memory task produced significant signal change in lateral and medial prefrontal cortex, precentral cortex, temporal lobe, including insula and hippocampus, parietal-occipital cortex, cingulate, thalamus, and superior colliculus. Performance and degree of activation was associated with an estimate of IQ. Further research should clarify the contributions of working memory and interference filtering to the activated network.
journal_name
Neuropsychologyjournal_title
Neuropsychologyauthors
Seidman LJ,Breiter HC,Goodman JM,Goldstein JM,Woodruff PW,O'Craven K,Savoy R,Tsuang MT,Rosen BRdoi
10.1037//0894-4105.12.4.505subject
Has Abstractpub_date
1998-10-01 00:00:00pages
505-18issue
4eissn
0894-4105issn
1931-1559journal_volume
12pub_type
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