Abstract:
OBJECTIVE:The literature on emotional processing in Parkinson's disease (PD) patients shows mixed results. This may be because of various methodological and/or patient-related differences, such as failing to adjust for cognitive functioning, depression, and/or mood. METHOD:In the current study, we tested PD patients and healthy controls (HCs) using emotional stimuli across a variety of tasks, including visual search, short-term memory (STM), categorical perception, and emotional stimulus rating. The PD and HC groups were matched on cognitive ability, depression, and mood. We also explored possible relationships between task results and antiparkinsonian treatment effects, as measured by levodopa equivalent dosages (LED), in the PD group. RESULTS:The results show that PD patients use a larger emotional range compared with HCs when reporting their impression of emotional faces on rated emotional valence, arousal, and potency. The results also show that dopaminergic therapy was correlated with stimulus rating results such that PD patients with higher LED scores rated negative faces as less arousing, less negative, and less powerful. Finally, results also show that PD patients display a general slowing effect in the visual search tasks compared with HCs, indicating overall slowed responses. There were no group differences observed in the STM or categorical perception tasks. CONCLUSIONS:Our results indicate a relationship between emotional responses, PD, and dopaminergic therapy, in which PD per se is associated with stronger emotional responses, whereas LED levels are negatively correlated with the strength of emotional responses. (PsycINFO Database Record
journal_name
Neuropsychologyjournal_title
Neuropsychologyauthors
Lundqvist D,Svärd J,Michelgård Palmquist Å,Fischer H,Svenningsson Pdoi
10.1037/neu0000371subject
Has Abstractpub_date
2017-09-01 00:00:00pages
605-612issue
6eissn
0894-4105issn
1931-1559pii
2017-24509-001journal_volume
31pub_type
杂志文章相关文献
NEUROPSYCHOLOGY文献大全abstract:OBJECTIVE:Two-alternative forced-choice tasks are widely used to gain insight into specific areas of enhancement or impairment in individuals with autism spectrum disorder (ASD). Data arising from these tasks have been used to support myriad theories regarding the integrity, or otherwise, of particular brain areas or c...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000320
更新日期:2017-02-01 00:00:00
abstract::Sixteen patients with Parkinson's disease (PD), 15 older controls (OCs), and 109 younger controls (YCs) were compared in 2 category-learning tasks. Participants attempted to assign colored geometric figures to 1 of 2 categories. In rule-based tasks, category membership was defined by an explicit rule that was easy to ...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Deficits in the ability to perceive time have been proposed as an etiologic mechanism in the development of the cognitive and behavioral characteristics associated with ADHD. However, previous studies testing the presence of timing deficits have produced idiosyncratic results. This is in large part due to the...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000562
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:Inconsistent performance is associated with cognitive dysfunction in a number of clinical populations. However, intraindividual cognitive variability in healthy individuals is poorly understood. Inconsistency poses a challenge to clinicians when interpreting change over time. This study examined intraindividu...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/a0033023
更新日期:2013-07-01 00:00:00
abstract::Two characteristics of word-list generation performance are forming clusters (i.e., contiguous words from the same subcategory) and switching among them. Patients with frontal lobe pathology show reduced switching on letter-cued word generation tasks, and clustering has been associated with temporal lobe functioning. ...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037//0894-4105.13.4.525
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:Disturbances in functional connectivity have been suggested to contribute to cognitive and emotion processing deficits observed in bipolar disorder (BD). Functional connectivity between medial prefrontal cortex (mPFC) and other brain regions may be particularly abnormal. The goal of the present study was to c...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000317
更新日期:2017-01-01 00:00:00
abstract::Inhibition of return (IOR) refers to an increase in time to react to a target in a previously attended location. Children with spina bifida meningomyelocele (SBM) and hydrocephalus have congenital dysmorphology of the midbrain, a brain region associated with the control of covert orienting in general and with IOR in p...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/0894-4105.19.4.456
更新日期:2005-07-01 00:00:00
abstract::A new analytical procedure, single common factor analysis, was carried out on the data from a relatively large sample of normals (n = 101) and patients with Alzheimer's disease (AD; n = 180) to examine the extent to which there were independent effects of disease status on different neuropsychological variables. This ...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037//0894-4105.12.2.242
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:Deficits in cognitive flexibility have been suggested to underlie the repetitive and stereotyped behavior in individuals with autism spectrum disorders (ASD). Because cognitive flexibility is primarily mediated by the frontal lobe, where structural and functional abnormalities have been extensively found in t...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000231
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To characterize variability in daily life functioning among individuals with serious mental illness based on a naturalistic performance measure of grocery shopping and standard neuropsychological tasks using cluster analytic methods. METHODS:A naturalistic performance measure, the Test of Grocery Shopping Sk...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000700
更新日期:2021-01-01 00:00:00
abstract::This exploratory study was conducted to increase understanding of neuropsychological test performance in those with blast-related mild traumatic brain injury (mTBI). The two variables of interest for their impact on test performance were presence of mTBI symptoms and history of posttraumatic stress disorder (PTSD). Fo...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/a0017966
更新日期:2010-03-01 00:00:00
abstract::Configural processing in autism was studied in Experiment 1 by using the face inversion effect. A normal inversion effect was observed in the participants with autism, suggesting intact configural face processing. A priming paradigm using partial or complete faces served in Experiment 2 to assess both local and config...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/0894-4105.20.1.30
更新日期:2006-01-01 00:00:00
abstract::In this study, the cognitive and neurochemical factors underlying learned irrelevance, one of the mechanisms thought to be responsible for attentional set-shifting deficits in Parkinson's disease (PD), were investigated. In a visual discrimination learning task, the extent to which a target dimension was irrelevant pr...
journal_title:Neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1037/0894-4105.20.5.578
更新日期:2006-09-01 00:00:00
abstract::Male and female left- and right-handers participated in 3 experiments designed to investigate 3 components of performance asymmetry in lateralized tasks. Experiment 1 used a consonant-vowel-consonant (CVC) identification task measuring quantitative differences in hemispheric abilities and hemispheric control and quali...
journal_title:Neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1037//0894-4105.11.4.562
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:Interference suppression and response inhibition are distinct effortful inhibitory processes. Yet they rely on partly overlapping neural substrates. Their independence was studied using an auditory paradigm. METHOD:Continuous EEG was recorded in 16 adults and event-related potentials (ERPs) were analyzed in ...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000586
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:Behavioral studies of spatial navigation in aging indicate that orientation using an allocentric reference frame (object-centered orientation) is impaired, whereas orientation using egocentric processes (self-centered orientation) is not. It has been proposed that navigational deficits may result from more ge...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000084
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The concept of overlapping neural networks supporting both speech production and fine motor praxis is well accepted; however, few studies have explored the lateralized behavioral characteristics of both functions when performed simultaneously. METHOD:This study probes the characteristics of the dominant hemi...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000589
更新日期:2019-11-01 00:00:00
abstract::Attention and memory performances were studied in Persian Gulf War veterans with and without posttraumatic stress disorder (PTSD) diagnoses. Veterans diagnosed with PTSD showed relative performance deficiencies on tasks of sustained attention, mental manipulation, initial acquisition of information, and retroactive in...
journal_title:Neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1037//0894-4105.12.1.125
更新日期:1998-01-01 00:00:00
abstract::Emotional arousal is associated with enhanced memory in neurologically intact individuals, but it is unknown whether this effect is obtained in Alzheimer's disease (AD). The current study compared emotional memory and emotional reactions in patients with early AD and in older controls. Participants viewed emotionally ...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:UNLABELLED:Reports an error in "Cognitive, emotion control, and motor performance of adolescents in the NCANDA study: Contributions from alcohol consumption, age, sex, ethnicity, and family history of addiction" by Edith V. Sullivan, Ty Brumback, Susan F. Tapert, Rosemary Fama, Devin Prouty, Sandra A. Brown, Kevin Cumm...
journal_title:Neuropsychology
pub_type: 杂志文章,已发布勘误
doi:10.1037/neu0000306
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Theory of Mind (ToM) is a multifaceted construct that involves mental states attribution in social interactions. Patients with schizophrenia are impaired in ToM abilities, but recent studies showed that a non-negligible number of patients perform within normal ranges or close to normal, whereas other patients...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000456
更新日期:2018-09-01 00:00:00
abstract::Bilateral presentations of words, 1 in the left visual hemifield (LVF) and 1 in the right (RVF), are used widely in studies of hemispheric asymmetry. However, although words shown centrally (i.e., nonlaterally) produce perceptual interactions in which 1 word alters the perceived identity of the other, perceptual inter...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/0894-4105.17.4.566
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:Traumatic brain injury (TBI) impairs emotion perception. Perception of negative emotions (sadness, disgust, fear, and anger) is reportedly affected more than positive (happiness and surprise) ones. It has been argued that this reflects a specialized neural network underpinning negative emotions that is vulner...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000171
更新日期:2015-07-01 00:00:00
abstract::Several strategies can be used to find a destination in the environment. Using a virtual environment, the authors identified 2 strategies dependent on 2 different memory systems. A spatial strategy involved the use of multiple landmarks available in the environment, and a response strategy involved right and left turn...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/0894-4105.18.3.418
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:The present study aimed to investigate prospective memory (PM) in persons with mild cognitive impairment (MCI). METHOD:Twenty individuals with MCI (10 with an amnestic profile and 10 with a dysexecutive profile of cognitive impairment) and 20 control subjects (CS) were recruited. In the PM tasks, subjects ha...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/a0018015
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:The purpose of the present study was to deepen our understanding of attention (a core cognitive ability) in Rett syndrome (RTT), an x-linked neurodevelopmental disorder caused by mutations in the MECP2 gene. We focused on 2 key aspects of visual orienting-shifting and disengaging attention-both of which are c...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000515
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The lack of inversion effect for face recognition in congenital prosopagnosia (CP) is consistent with the hypothesis of a failure in holistic processing. However, although CPs' abnormal gaze behavior for upright faces has already been demonstrated, neither their scanning strategy for inverted faces, nor the p...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000362
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:An increasing number of results show that specific language impairment (SLI) is often associated with impairments in executive functions (EF), but the nature, extent, and generality of these deficits is yet unclear. The aim of the paper is to present results from verbal and nonverbal tasks examining EF in chi...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/neu0000232
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:Twenty-five years ago, the field of neuropsychology was well established in North America, Europe, and Australia, with less presence elsewhere. This article discusses the development of neuropsychology over the last 25 years in other regions. METHOD:The growth of neuropsychology in Asia, Africa, the Middle E...
journal_title:Neuropsychology
pub_type: 杂志文章,评审
doi:10.1037/neu0000415
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Cognitive impairments in theory of mind (ToM), executive processing, and decision-making are frequent and highly relevant symptoms in patients with Parkinson's disease (PD). These functions have been related to moral decision-making. Their association to moral decision-making in PD, however, has not been stud...
journal_title:Neuropsychology
pub_type: 杂志文章
doi:10.1037/a0033595
更新日期:2013-09-01 00:00:00