Influenza virus hemagglutinin stimulates the protein kinase C activity of human polymorphonuclear leucocytes.

Abstract:

:Human polymorphonuclear leukocytes (PMNL) incubated with influenza virus, A/USSR/90/77 (H1N1) or its hemagglutinin produced a significant increase in their PKC activity when compared with untreated PMNL. The activated kinase translocated from cytosol to cellular membrane. The calcium-dependent enzyme activity was inhibited by a specific inhibitor suggesting that alpha and/or beta isoforms of PKC were involved.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Arora DJ,Gasse N

doi

10.1007/s007050050439

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

2029-37

issue

10

eissn

0304-8608

issn

1432-8798

journal_volume

143

pub_type

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