Abstract：
:cDNA clones spanning the entire region of the peplomer (S) gene of feline infectious peritonitis virus (FIPV) type I strain KU-2 were obtained and their complete nucleotide sequences were determined. A long open reading frame (ORF) encoding 1464 amino acid residues was found in the gene, which was 12 residues longer than the ORF of the FIPV type II strain 79-1146. The sequences of FIPV type I and mainly -tPV type II were compared. The homologies at the N- (amino acid residues 1-693) and C- (residues 694-1464) terminal halves were 29.8 and 60.7%, respectively. This was much lower than that between FIPV type II and other antigenically related coronaviruses, such as transmissible gastroenteritis virus of swine and canine coronavirus. This supported the serological relatedness of the viruses and confirmed that the peplomer protein of FIPV type I has distinct structural features that differ from those of antigenically related viruses.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Motokawa K,Hohdatsu T,Aizawa C,Koyama H,Hashimoto Hdoi
10.1007/BF01718424subject
Has Abstractpub_date
1995-01-01 00:00:00pages
469-80issue
3eissn
0304-8608issn
1432-8798journal_volume
140pub_type
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