Abstract：
:HIV-1 genetic diversity information from a pediatric population is scarce. This study enrolled 128 children living with HIV/AIDS, 103 antiretroviral-treated and 25 naive, from the Sao Paulo metropolitan area. Gag, pol and env regions were amplified, and drug resistance mutations, V3 loop, tropism and viral clades were evaluated. Drug resistance mutations among naïve children infected by vertical transmission were uncommon (4.2%), whereas most ARV-experienced children showed extensive mutation patterns. Clade B predominated at the pol region, but the analysis of the three regions concatenated showed 28% with BF mosaic structures. The most common V3 motif was GPGR, followed by GWGR in clade B samples and GPGQ in clade F samples. A predicted X4 phenotype was observed in 27%, without correlation to HIV clade. These findings expand the limited information on molecular characteristics of HIV-1 among children living with HIV/AIDS in the area and may provide information useful for monitoring the epidemic.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
de Oliveira CM,Almeida FJ,Rodrigues R,Crozatti M,Vazquez CM,do Socorro Carneiro Ferrão M,Campeas AE,Marques SR,Berezin EN,de Macedo Brígido LFdoi
10.1007/s00705-008-0178-7subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1799-806issue
10eissn
0304-8608issn
1432-8798journal_volume
153pub_type
杂志文章abstract：:Salmonella phages SenALZ1 and SenASZ3, two novel phages infecting Salmonella enterica, were isolated and analyzed. The genomes of these two phages consist of 154,811 and 157,630 base pairs (bp), with G+C contents of 44.56% and 44.74%, respectively. Fifty-nine of 199 open reading frames (ORFs) in the SenALZ1 genome, an...
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journal_title：Archives of virology
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doi：
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journal_title：Archives of virology
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doi：10.1007/s00705-005-0491-3
更新日期：2005-06-01 00:00:00
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更新日期：2017-03-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00705-017-3565-0
更新日期：2018-01-01 00:00:00
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journal_title：Archives of virology
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doi：10.1007/s00705-016-3037-y
更新日期：2016-12-01 00:00:00
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journal_title：Archives of virology
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doi：10.1007/BF01310965
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journal_title：Archives of virology
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更新日期：1984-01-01 00:00:00
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doi：10.1007/s00705-006-0899-4
更新日期：2007-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
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更新日期：1991-01-01 00:00:00
abstract：:Concentrations of DEAE-dextran which are currently used to stimulate the interaction between animal cells and natural or synthetic polynucleotides, inhibit protein synthesis in HeLa cells. This inhibition results from the blocking of more than one of the steps in protein synthesis, including transport of amino acids. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF02175599
更新日期：1975-01-01 00:00:00
abstract：:In this study, RNA corresponding to bovine enterovirus (BEV) was detected in 24.6 % of faecal samples (17/69) from diarrheic and healthy cattle in six different areas in China by an RT-PCR screening method. Furthermore, two cytopathic agents, designated as BHM26 and BJ50, were isolated from the bovine diarrheic fecal ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1424-6
更新日期：2012-12-01 00:00:00
abstract：:The '6K1' protein of the Pinellia isolate of Soybean mosaic virus was cloned into a prokaryotic expression vector and a polyclonal antiserum raised to the expressed fusion protein. In immunogold labeling of thin sections of infected leaves of Pinellia ternata, specific labeling occurred at the cell periphery. This mig...
journal_title：Archives of virology
pub_type： 杂志文章
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更新日期：2007-01-01 00:00:00
abstract：:TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% preva...
journal_title：Archives of virology
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更新日期：2002-01-01 00:00:00
