Predominance of hepatitis B virus genotype C among Karens, the 'old settlers' of Andaman and Nicobar Islands, India.

Abstract:

:The Karens, or 'old settlers', migrated from Myanmar to Andaman and Nicobar islands 80 years ago. A high HBV exposure rate among them has been reported. A study of 34 HBsAg carriers was done to investigate the origin of HBV infection among the Karens. RFLP-based genotyping was confirmed by sequencing and phylogenetic analysis. The predominance of HBV/C1/Cs suggests that they carried HBV during their migration, retained it, and in addition, acquired HBV/D2 from the people of mainland India. The reported association of HBV genotype C with disease severity thus warrants further epidemiological investigations among them and on possible spread among neighboring settlers.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Datta S,Chandra PK,Banerjee A,Chakravarty R,Murhekar KM,Murhekar MV

doi

10.1007/s00705-006-0910-0

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

1223-8

issue

6

eissn

0304-8608

issn

1432-8798

journal_volume

152

pub_type

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