Molecular detection and genetic diversity of norovirus genogroup IV: a yearlong monitoring of sewage throughout Italy.

Abstract:

:Noroviruses cause acute viral gastroenteritis worldwide. They are classified in five genogroups, of which GI, GII, and GIV infect humans. Little information is available on the prevalence and clinical effects of GIV noroviruses. We conducted a large-scale molecular-epidemiological investigation, a yearlong monitoring of 11 wastewater treatment plants throughout Italy, with the aim of studying the circulation of GIV NoV, as well as its genetic diversity. Eight percent of samples tested positive, and sequence analysis showed a considerable degree of genetic variability. These results imply the need for further studies to elucidate the role of this virus as a gastroenteritis-causing pathogen.

journal_name

Arch Virol

journal_title

Archives of virology

authors

La Rosa G,Iaconelli M,Pourshaban M,Fratini M,Muscillo M

doi

10.1007/s00705-010-0619-y

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

589-93

issue

4

eissn

0304-8608

issn

1432-8798

journal_volume

155

pub_type

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