Cortical area MT and the perception of stereoscopic depth.

Abstract:

:Stereopsis is the perception of depth based on small positional differences between images formed on the two retinae (known as binocular disparity). Neurons that respond selectively to binocular disparity were first described three decades ago, and have since been observed in many visual areas of the primate brain, including V1, V2, V3, MT and MST. Although disparity-selective neurons are thought to form the neural substrate for stereopsis, the mere existence of disparity-selective neurons does not guarantee that they contribute to stereoscopic depth perception. Some disparity-selective neurons may play other roles, such as guiding vergence eye movements. Thus, the roles of different visual areas in stereopsis remain poorly defined. Here we show that visual area MT is important in stereoscopic vision: electrical stimulation of clusters of disparity-selective MT neurons can bias perceptual judgements of depth, and the bias is predictable from the disparity preference of neurons at the stimulation site. These results show that behaviourally relevant signals concerning stereoscopic depth are present in MT.

journal_name

Nature

journal_title

Nature

authors

DeAngelis GC,Cumming BG,Newsome WT

doi

10.1038/29299

subject

Has Abstract

pub_date

1998-08-13 00:00:00

pages

677-80

issue

6694

eissn

0028-0836

issn

1476-4687

journal_volume

394

pub_type

杂志文章

相关文献

NATURE文献大全
  • Human cell-surface glycoprotein with unusual properties.

    abstract::We report here the identification of human cell-surface glycoprotein with unusual and interesting properties. We initially detected this glycoprotein on the surface of cultured human haematopoietic cell lines by means of a monoclonal antibody. Although it is expressed on all cultured human haematopoietic cell lines te...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/286888a0

    authors: Omary MB,Trowbridge IS,Minowada J

    更新日期:1980-08-28 00:00:00

  • Speciation in a ring.

    abstract::The evolutionary divergence of a single species into two has never been directly observed in nature, primarily because speciation can take a long time to occur. A ring species, in which a chain of intergrading populations encircles a barrier and the terminal forms coexist without interbreeding, provides a situation in...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35053059

    authors: Irwin DE,Bensch S,Price TD

    更新日期:2001-01-18 00:00:00

  • Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin.

    abstract::The sensation of pain is carried to the central nervous system by small-diameter fibres which terminate in the superficial layers of the spinal grey matter, particularly the substantia gelatinosa. Opiate drugs administered into the substantia gelatinosa inhibit the excitation of deeper dorsal horn neurones by noxious ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/305529a0

    authors: Yoshimura M,North RA

    更新日期:1983-10-06 00:00:00

  • The dynamics of molecular evolution over 60,000 generations.

    abstract::The outcomes of evolution are determined by a stochastic dynamical process that governs how mutations arise and spread through a population. However, it is difficult to observe these dynamics directly over long periods and across entire genomes. Here we analyse the dynamics of molecular evolution in twelve experimenta...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature24287

    authors: Good BH,McDonald MJ,Barrick JE,Lenski RE,Desai MM

    更新日期:2017-11-02 00:00:00

  • Horsetails and ferns are a monophyletic group and the closest living relatives to seed plants.

    abstract::Most of the 470-million-year history of plants on land belongs to bryophytes, pteridophytes and gymnosperms, which eventually yielded to the ecological dominance by angiosperms 90 Myr ago. Our knowledge of angiosperm phylogeny, particularly the branching order of the earliest lineages, has recently been increased by t...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35054555

    authors: Pryer KM,Schneider H,Smith AR,Cranfill R,Wolf PG,Hunt JS,Sipes SD

    更新日期:2001-02-01 00:00:00

  • Corrigendum: Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.

    abstract::This corrects the article DOI: 10.1038/nature22794. ...

    journal_title:Nature

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/nature25162

    authors: Shaffer SM,Dunagin MC,Torborg SR,Torre EA,Emert B,Krepler C,Beqiri M,Sproesser K,Brafford PA,Xiao M,Eggan E,Anastopoulos IN,Vargas-Garcia CA,Singh A,Nathanson KL,Herlyn M,Raj A

    更新日期:2018-03-08 00:00:00

  • Evolution of RNA editing in kinetoplastid protozoa.

    abstract::The editing of RNA in trypanosomatid mitochondria involves the insertion and occasional deletion of uridine residues within coding regions of maxicircle messenger RNA transcripts. The extent to which the transcripts of homologous genes undergo editing differs in different species. In some, entire genes are edited (pan...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/368345a0

    authors: Maslov DA,Avila HA,Lake JA,Simpson L

    更新日期:1994-03-24 00:00:00

  • Antibody-mediated enhancement of Flavivirus replication in macrophage-like cell lines.

    abstract::Interactions between animal viruses and antiviral antisera may exceptionally result in an apparent increase in viral infectivity. Halstead and coworkers demonstrated enhanced replication of dengue virus (a Flavivirus, family Togaviridae) in human or simian peripheral blood leucocytes carrying Fc receptors at subneutra...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/282509a0

    authors: Peiris JS,Porterfield JS

    更新日期:1979-11-29 00:00:00

  • Deformation cycles of subduction earthquakes in a viscoelastic Earth.

    abstract::Subduction zones produce the largest earthquakes. Over the past two decades, space geodesy has revolutionized our view of crustal deformation between consecutive earthquakes. The short time span of modern measurements necessitates comparative studies of subduction zones that are at different stages of the deformation ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature11032

    authors: Wang K,Hu Y,He J

    更新日期:2012-04-18 00:00:00

  • Adenylyl cyclases and the interaction between calcium and cAMP signalling.

    abstract::Adenylyl cyclase is the prototypical second messenger generator. Nearly all of the eight cloned adenylyl cyclases are regulated by one or other arm of the phospholipase C pathway. Functional and ultrastructural investigations have shown that adenylyl cyclases are intimately associated with sites of calcium ion entry i...

    journal_title:Nature

    pub_type: 杂志文章,评审

    doi:10.1038/374421a0

    authors: Cooper DM,Mons N,Karpen JW

    更新日期:1995-03-30 00:00:00

  • Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes.

    abstract::The human AIDS viruses human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) represent cross-species (zoonotic) infections. Although the primate reservoir of HIV-2 has been clearly identified as the sooty mangabey (Cercocebus atys), the origin of HIV-1 remains uncertain. Viruses related to HIV-1 have been iso...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/17130

    authors: Gao F,Bailes E,Robertson DL,Chen Y,Rodenburg CM,Michael SF,Cummins LB,Arthur LO,Peeters M,Shaw GM,Sharp PM,Hahn BH

    更新日期:1999-02-04 00:00:00

  • Imprisoned academics, China's Moon lander and AI moral code.

    abstract:: ...

    journal_title:Nature

    pub_type: 新闻

    doi:10.1038/d41586-018-07667-5

    authors:

    更新日期:2018-12-01 00:00:00

  • Endstopped neurons in the visual cortex as a substrate for calculating curvature.

    abstract::Neurons in the visual cortex typically respond selectively to the orientation, and velocity and direction of movement, of moving-bar stimuli. These responses are generally thought to provide information about the orientation and position of lines and edges in the visual field. Some cells are also endstopped, that is s...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/329438a0

    authors: Dobbins A,Zucker SW,Cynader MS

    更新日期:1987-10-01 00:00:00

  • Structural basis for action by diverse antidepressants on biogenic amine transporters.

    abstract::The biogenic amine transporters (BATs) regulate endogenous neurotransmitter concentrations and are targets for a broad range of therapeutic agents including selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs). Because eukaryotic BATs...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature12648

    authors: Wang H,Goehring A,Wang KH,Penmatsa A,Ressler R,Gouaux E

    更新日期:2013-11-07 00:00:00

  • Chimpanzees and AIDS research.

    abstract::Pressure is mounting to relax the regulations on importation of chimpanzees for research. Such a policy is unnecessary and would deepen the plight of an already endangered species. ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/333513a0

    authors: Prince AM,Moor-Jankowski J,Eichberg JW,Schellekens H,Mauler RF,Girard M,Goodall J

    更新日期:1988-06-09 00:00:00

  • An analogue approach to the travelling salesman problem using an elastic net method.

    abstract::The travelling salesman problem is a classical problem in the field of combinatorial optimization, concerned with efficient methods for maximizing or minimizing a function of many independent variables. Given the positions of N cities, which in the simplest case lie in the plane, what is the shortest closed tour in wh...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/326689a0

    authors: Durbin R,Willshaw D

    更新日期:1987-04-16 00:00:00

  • Tumour exosome integrins determine organotropic metastasis.

    abstract::Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour cells fuse preferentially with resident cells at their predicted destination, namely lung fibroblasts and ep...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature15756

    authors: Hoshino A,Costa-Silva B,Shen TL,Rodrigues G,Hashimoto A,Tesic Mark M,Molina H,Kohsaka S,Di Giannatale A,Ceder S,Singh S,Williams C,Soplop N,Uryu K,Pharmer L,King T,Bojmar L,Davies AE,Ararso Y,Zhang T,Zhang H,Her

    更新日期:2015-11-19 00:00:00

  • Crystal structure of a yeast TFIIA/TBP/DNA complex.

    abstract::The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/381127a0

    authors: Tan S,Hunziker Y,Sargent DF,Richmond TJ

    更新日期:1996-05-09 00:00:00

  • BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.

    abstract::Genome instability is central to ageing, cancer and other diseases. It is not only proteins involved in DNA replication or the DNA damage response (DDR) that are important for maintaining genome integrity: from yeast to higher eukaryotes, mutations in genes involved in pre-mRNA splicing and in the biogenesis and expor...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature13374

    authors: Bhatia V,Barroso SI,García-Rubio ML,Tumini E,Herrera-Moyano E,Aguilera A

    更新日期:2014-07-17 00:00:00

  • Asymmetric neurotransmitter release enables rapid odour lateralization in Drosophila.

    abstract::In Drosophila, most individual olfactory receptor neurons (ORNs) project bilaterally to both sides of the brain. Having bilateral rather than unilateral projections may represent a useful redundancy. However, bilateral ORN projections to the brain should also compromise the ability to lateralize odours. Nevertheless, ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature11747

    authors: Gaudry Q,Hong EJ,Kain J,de Bivort BL,Wilson RI

    更新日期:2013-01-17 00:00:00

  • Decline of surface temperature and salinity in the western tropical Pacific Ocean in the Holocene epoch.

    abstract::In the present-day climate, surface water salinities are low in the western tropical Pacific Ocean and increase towards the eastern part of the basin. The salinity of surface waters in the tropical Pacific Ocean is thought to be controlled by a combination of atmospheric convection, precipitation, evaporation and ocea...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature02903

    authors: Stott L,Cannariato K,Thunell R,Haug GH,Koutavas A,Lund S

    更新日期:2004-09-02 00:00:00

  • Molecular structure of F-actin and location of surface binding sites.

    abstract::Comparisons of three-dimensional maps of vertebrate muscle thin filaments obtained by cryo-electron microscopy and image analysis, reveal the molecular structure of F-actin, the location of the C terminus of the monomer and the positions of the binding sites of tropomyosin, the myosin head and the N-terminal portion o...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/348217a0

    authors: Milligan RA,Whittaker M,Safer D

    更新日期:1990-11-15 00:00:00

  • A system hierarchy for brain-inspired computing.

    abstract::Neuromorphic computing draws inspiration from the brain to provide computing technology and architecture with the potential to drive the next wave of computer engineering1-13. Such brain-inspired computing also provides a promising platform for the development of artificial general intelligence14,15. However, unlike c...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-020-2782-y

    authors: Zhang Y,Qu P,Ji Y,Zhang W,Gao G,Wang G,Song S,Li G,Chen W,Zheng W,Chen F,Pei J,Zhao R,Zhao M,Shi L

    更新日期:2020-10-01 00:00:00

  • High-frequency genomic rearrangements involving archaebacterial repeat sequence elements.

    abstract::Halobacterium halobium is an obligately halophilic archaebacterium of interest to molecular biologists for many reasons, one of which is the unexplained high frequency (10(-4)-10(-2) mutants per cell plated) at which it yields readily identifiable and unstable mutants. We showed previously that the genome of H. halobi...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/299182a0

    authors: Sapienza C,Rose MR,Doolittle WF

    更新日期:1982-09-09 00:00:00

  • The Ndc80 kinetochore complex forms oligomeric arrays along microtubules.

    abstract::The Ndc80 complex is a key site of regulated kinetochore-microtubule attachment (a process required for cell division), but the molecular mechanism underlying its function remains unknown. Here we present a subnanometre-resolution cryo-electron microscopy reconstruction of the human Ndc80 complex bound to microtubules...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature09423

    authors: Alushin GM,Ramey VH,Pasqualato S,Ball DA,Grigorieff N,Musacchio A,Nogales E

    更新日期:2010-10-14 00:00:00

  • Specific expression of a silk-encoding gene of Bombyx in the anterior salivary gland of Drosophila.

    abstract::Successful expression of genes transferred into distantly related species in which genetic functions have been maintained through evolution has been reported previously. In the case of the silkmoth Bombyx mori and the fruitfly Drosophila melanogaster, both of which produce chorions (eggshells), Bombyx chorion genes ar...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/346480a0

    authors: Bello B,Couble P

    更新日期:1990-08-02 00:00:00

  • Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro.

    abstract::Insulin resistance occurs in a variety of conditions, including diabetes, obesity and essential hypertension, but its underlying molecular mechanisms are unclear. In type 2 (non-insulin-dependent) diabetes mellitus, it is insulin-resistance in skeletal muscle, the chief site of insulin-mediated glucose disposal in hum...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/335632a0

    authors: Leighton B,Cooper GJ

    更新日期:1988-10-13 00:00:00

  • Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II.

    abstract::Phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II is believed to control the transition from transcription initiation to elongation. The general transcription factor IIH (TFIIH) contains a kinase activity capable of phosphorylating this domain. Factors that promote the associat...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/358641a0

    authors: Lu H,Zawel L,Fisher L,Egly JM,Reinberg D

    更新日期:1992-08-20 00:00:00

  • Machine learning helps to hunt down the cause of a paralysing illness.

    abstract:: ...

    journal_title:Nature

    pub_type: 新闻

    doi:10.1038/d41586-018-07631-3

    authors: Reardon S

    更新日期:2018-12-01 00:00:00

  • X-ray structure of a mammalian stearoyl-CoA desaturase.

    abstract::Stearoyl-CoA desaturase (SCD) is conserved in all eukaryotes and introduces the first double bond into saturated fatty acyl-CoAs. Because the monounsaturated products of SCD are key precursors of membrane phospholipids, cholesterol esters and triglycerides, SCD is pivotal in fatty acid metabolism. Humans have two SCD ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature14549

    authors: Bai Y,McCoy JG,Levin EJ,Sobrado P,Rajashankar KR,Fox BG,Zhou M

    更新日期:2015-08-13 00:00:00