Effects of air pollution and other environmental factors on birch pollen allergens.

abstract：:Basophilocytes from patients with rheumatoid arthritis (RA) responded to leukocyte nuclei from normal persons with histamine release; a similar histamine release induced by the nuclear components RNA and DNA has been demonstrated previously. A role of histamine in RA is also supported by the findings of clinical impro...

journal_title：Allergy

authors： Permin H,Skov PS,Norn S,Geisler A,Klysner R,Andersen V,Wiik A,Manthorpe R,Nielsen H,Petersen J

更新日期：1981-08-01 00:00:00

abstract：:Screening of total IgE in 2814 cord blood samples was analysed by Phadebas IgE PRIST in 2 1-year birth cohorts (1983-1984 and 1985-1986) in Denmark (n = 1189 + 1625). 48.6% of the sera contained less IgE than the detection limit 0.1 kU/l. Cord blood IgE values greater than or equal to 0.5 kU/l were regarded as elevate...

journal_title：Allergy

authors： Hansen LG,Høst A,Halken S,Holmskov A,Husby S,Lassen LB,Storm K,Osterballe O

更新日期：1992-08-01 00:00:00

abstract：:Work-related asthma is the most common occupational respiratory disorder in the industrialized countries. It has been postulated that wood dust exposure may increase the risk of work-related asthma. The objective of this study was to assess, through a meta-analysis, the risk of developing work-related asthma associate...

journal_title：Allergy

authors： Pérez-Ríos M,Ruano-Ravina A,Etminan M,Takkouche B

更新日期：2010-04-01 00:00:00

abstract：:The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line of defense. Apart from the well-described physical barrier and the mucociliary clearance, a variety of systems, including the airway microbiome, antimicrobial pr...

journal_title：Allergy

authors： Zhang N,Van Crombruggen K,Gevaert E,Bachert C

更新日期：2016-03-01 00:00:00

abstract：:The prevalence and specificity of naturally occurring human IgA anti-IgE autoantibodies (a-E Ab) were studied by ELISA with anti-IgA monoclonal antibodies (mAb) and a purified myeloma IgE as solid-phase protein, i.e., IgE-DES(kappa). Such detected IgA a-E Ab were common among adults, and significantly increased geomet...

journal_title：Allergy

authors： Magnusson CG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:The genetic determinants of food allergy have not been systematically reviewed. We therefore systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation. METHODS:We searched three electronic databases (MEDLINE, EMBASE and PubMed) on 9 January 2018...

journal_title：Allergy

authors： Suaini NHA,Wang Y,Soriano VX,Martino DJ,Allen KJ,Ellis JA,Koplin JJ

更新日期：2019-09-01 00:00:00

abstract：:Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both activated human and mouse basophils can form extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins. In this report, we provide eviden...

journal_title：Allergy

authors： Yousefi S,Morshed M,Amini P,Stojkov D,Simon D,von Gunten S,Kaufmann T,Simon HU

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergen exposure time periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end...

journal_title：Allergy

authors： Karatzas K,Katsifarakis N,Riga M,Werchan B,Werchan M,Berger U,Pfaar O,Bergmann KC

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Latex sensitivity is an increasing problem among health-care workers. Allergic responses are associated with changes in nitric oxide (NO) generation and the changes secondary to latex have not been described. METHODS:A total of 22 subjects comprising equal numbers of control volunteers and subjects with sel...

journal_title：Allergy

authors： Tan K,Bruce C,Birkhead A,Thomas PS

更新日期：2001-07-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：:Formoterol and salmeterol are 2 newly developed beta 2-adrenoceptor agonists for inhalation with prolonged duration of effect compared with currently available beta 2-agonists. The clinical duration of effect has been suggested to be correlated to a decreased washability in vitro, i.e. decreased effect due to continuo...

journal_title：Allergy

authors： Ullman A,Bergendal A,Lindén A,Waldeck B,Skoogh BE,Löfdahl CG

更新日期：1992-08-01 00:00:00

abstract：:The increase in allergic airway disease has paralleled the increase in the use of fossil fuels. Studies were undertaken to examine whether extracts of polyaromatic hydrocarbons (PAH) from diesel exhaust particles (DEP) (PAH-DEP) acted as mucosal adjuvants to help initiate or enhance immunoglobulin E (IgE) production i...

journal_title：Allergy

authors： Diaz-Sanchez D

更新日期：1997-01-01 00:00:00

abstract：:Cocksfoot/orchard grass (Dactylis glomerata) anther cDNA clones encoding the group II allergen Dac g II were previously isolated on the basis of immunoreactivity of human, rabbit, and murine antibodies with a 24-kDa protein expressed as a fusion protein with beta-galactosidase. Nucleotide sequencing reveals an open re...

journal_title：Allergy

authors： Roberts AM,Bevan LJ,Flora PS,Jepson I,Walker MR

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. METHODS:We performed oral food challenges in 21 apple-allergic individuals with Elstar apples which had undergone gene ...

journal_title：Allergy

authors： Dubois AE,Pagliarani G,Brouwer RM,Kollen BJ,Dragsted LO,Eriksen FD,Callesen O,Gilissen LJ,Krens FA,Visser RG,Smulders MJ,Vlieg-Boerstra BJ,Flokstra-de Blok BJ,van de Weg WE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has been identified as the major birch pollen allergen. However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 and other components of the birch pollen extract, remain incompletely understoo...

journal_title：Allergy

authors： Soh WT,Aglas L,Mueller GA,Gilles S,Weiss R,Scheiblhofer S,Huber S,Scheidt T,Thompson PM,Briza P,London RE,Traidl-Hoffmann C,Cabrele C,Brandstetter H,Ferreira F

更新日期：2019-12-01 00:00:00

abstract：:Dialysed extracts of alder (Alnus glutinosa) and hazel (Corylus avellana) pollens were characterized by immunochemical methods. The alder pollen extract contained at least 33 distinct antigens of which one, antigen 5, was classified as a major allergen, three, antigens 4, 10, and 17, were classified as intermediate al...

journal_title：Allergy

authors： Ipsen H,Bøwadt H,Janniche H,Nüchel Petersen B,Munch EP,Wihl JA,Løwenstein H

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Mannitol-induced bronchoconstriction in subjects with exercise-induced asthma is associated with increased urinary excretion of 9alpha, 11beta-PGF(2), a metabolite of prostaglandin D(2) (PGD(2)) serving as a mast cell marker. It has however been questioned whether or not human mast cells release PGD(2) and l...

journal_title：Allergy

authors： Gulliksson M,Palmberg L,Nilsson G,Ahlstedt S,Kumlin M

更新日期：2006-12-01 00:00:00

abstract：:This paper presents the response in subjects with asthma to gaseous air-pollution levels, weather, and medicine intake as identified by principal-component analysis and neural network techniques. Pulmonary function measured by respiratory peak-flow rate in nonallergic asthmatics was associated with ambient, low-level,...

journal_title：Allergy

authors： Moseholm L,Taudorf E,Frøsig A

更新日期：1993-07-01 00:00:00

abstract：:The estimation of exposure to molds and their products in the indoor environment, which may lead to the occurrence of allergies or respiratory complaints, by means of enumeration of viable parts is inadequate. Therefore, other methods must be developed. When grown under various circumstances (22 degrees C and 30 degre...

journal_title：Allergy

authors： Wijnands LM,Deisz WD,van Leusden FM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Several studies showed that calcium-binding proteins have a fixed place in the spectrum of allergenic substances. Often the binding of a calcium ion induces conformational changes and affects immunoglobulin E-binding to the allergen. Hence, the quantitative characterization of the binding to calcium is of im...

journal_title：Allergy

authors： Hebenstreit D,Ferreira F

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Immunoglobulin E (IgE)-mediated allergy belongs to common chronic disorders resulting from an interaction between both genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31.1, a region that is linked to asthma and ...

journal_title：Allergy

authors： Bucková D,Hollá LI,Schüller M,Znojil V,Vácha J

更新日期：2003-10-01 00:00:00

abstract：:The standard treatment of allergic rhinitis and asthma consists of topical corticosteroids administered intranasally and inhaled through the mouth. Although this therapy is highly effective, and side-effects are few and mild, it may be possible further to improve the therapeutic index and patient compliance with the t...

journal_title：Allergy

authors： Pedersen W,Hjuler I,Bisgaard H,Mygind N

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmin, initiating and propagating danger signals resulting from tissue injury or inflammatory stimuli. The contribution of this immune sensing pathway to the development of allergic and inflammatory responses is unkn...

journal_title：Allergy

authors： Rubić-Schneider T,Carballido-Perrig N,Regairaz C,Raad L,Jost S,Rauld C,Christen B,Wieczorek G,Kreutzer R,Dawson J,Lametschwandner G,Littlewood-Evans A,Carballido JM

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Fluorescence-labeled MHC class II/peptide tetramer complexes are considered as optimal tools to characterize allergen-specific CD4(+) T cells, but this technique is restricted to frequently expressed HLA class II molecules and knowledge of immunodominant epitopes. In contrast, allergen-stimulated proliferati...

journal_title：Allergy

authors： Van Hemelen D,Mahler V,Fischer G,Fae I,Reichl-Leb V,Pickl W,Jutel M,Smolinska S,Ebner C,Bohle B,Jahn-Schmid B

更新日期：2015-01-01 00:00:00

abstract：:For screening atopy risk in 6401 (84%) of all infants born during the year 1990 in six obstetric departments of five German cities, cord-blood IgE values were determined with CAP-RAST-FEIA. After cases with elevated IgA values had been excluded, 25% of the values were above the detection limit of 0.35 kU/l, and 8.5% w...

journal_title：Allergy

authors： Bergmann RL,Schulz J,Günther S,Dudenhausen JW,Bergmann KE,Bauer CP,Dorsch W,Schmidt E,Luck W,Lau S

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Subjective symptoms after food challenges are difficult to interpret and no standard is available. We discuss a strategy for how to interpret a diary. Furthermore, the interobserver reliability is evaluated. METHODS:Diaries for 32 patients with subjective symptoms were used. The diaries were re-evaluated wi...

journal_title：Allergy

authors： Gellerstedt M,Magnusson J,Gråjö U,Ahlstedt S,Bengtsson U

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Rhinitis symptoms and IgE-sensitization often mismatch. Asymptomatic sensitization is an established risk factor for later rhinitis, whereas it is not clear whether rhinitis is a risk factor for later development of IgE-sensitization. OBJECTIVE:To investigate whether nonallergic rhinitis is a risk factor fo...

journal_title：Allergy

authors： Bodtger U,Poulsen LK,Linneberg A

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:To date, there has been no reliable in vitro test to either diagnose or differentiate nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD). The aim of the present study was to develop and validate an artificial neural network (ANN) for the prediction of N-ERD in patients with a...

journal_title：Allergy

authors： Tyrak KE,Pajdzik K,Konduracka E,Ćmiel A,Jakieła B,Celejewska-Wójcik N,Trąd G,Kot A,Urbańska A,Zabiegło E,Kacorzyk R,Kupryś-Lipińska I,Oleś K,Kuna P,Sanak M,Mastalerz L

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

journal_title：Allergy

authors： Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

更新日期：2019-10-01 00:00:00

abstract：:Soluble interleukin-2 receptor (sIL-2R), eosinophil cationic protein (ECP), the lymphoproliferative response to house-dust mite (HDM), adhesion to human umbilical vein endothelial cells (HUVEC), and lymphocyte membrane markers were studied in three groups of children: healthy children, asthmatic children without hypos...

journal_title：Allergy

authors： Moens MM,Van Bever HP,Stevens WJ,Mertens AV,Bridts CH,De Clerck LS

更新日期：1994-09-01 00:00:00