Food allergy endotype with high risk of severe anaphylaxis in children-Monosensitization to cashew 2S albumin Ana o 3.

abstract：:Azelastine hydrochloride, chemically known as 1(2H)-phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepine-4-yl)-, monohydrochloride, is a novel, orally effective, long-acting, antiallergic/antiasthmatic agent. The ability of azelastine and selected antiallergic drugs to inhibit SRS-A (leukotriene)...

journal_title：Allergy

authors： Chand N,Nolan K,Diamantis W,Perhach JL Jr,Sofia RD

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Two-flow cytometry methods for quantification of degranulated basophil after allergen-specific activation were discussed. The methods are discerned by used membrane receptors--FcepsilonRI or IL-3Ralpha Our goal was to evaluate the diagnostic potential of the methods and to correlate them to allergen-specific...

journal_title：Allergy

authors： Michova A,Abugalia M,Ivanova Ts,Nikolov G,Taskov H,Petrunov B

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The capacity of profilin to induce allergic symptoms in patients with respiratory allergy has been questioned. In this sense, the aim of this study was to investigate the correlation between profilin exposure and induction of symptoms in a prospective case-control study. METHODS:The concentration of profili...

journal_title：Allergy

authors： Ruiz-Hornillos J,López-Matas MA,Berges Jimeno P,Henríquez A,Blanco S,Seoane-Rodríguez M,Mahíllo I,Carnés J

更新日期：2020-04-01 00:00:00

abstract：:Subcellular sites of histamine in purified human lung mast cells and human peripheral blood basophils were determined using a newly developed enzyme-gold affinity method for ultrastructural analysis. The evolving morphologies of regulated secretion and recovery from regulated secretion in each cell showed that granule...

journal_title：Allergy

authors： Dvorak AM

更新日期：1997-01-01 00:00:00

abstract：:In order to establish reference values for total serum IgE in an adult non-atopic population, 175 individuals, 17-85 years of age, were investigated. The usefulness of a sensitive method (PRIST) for serum IgE determinations in discriminating atopy from non-atopic conditions in allergological routine diagnosis was eluc...

journal_title：Allergy

authors： Zetterström O,Johansson SG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Atopy, the overall tendency to become sensitized to an allergen, is heritable but seldom ascribed to mutations within specific genes. Atopic individuals develop abnormally elevated IgE responses to immunization with potential allergens. To gain insight into the genetic causes of atopy, we carried out a forwa...

journal_title：Allergy

authors： SoRelle JA,Chen Z,Wang J,Yue T,Choi JH,Wang KW,Zhong X,Hildebrand S,Russell J,Scott L,Xu D,Zhan X,Bu CH,Wang T,Choi M,Tang M,Ludwig S,Zhan X,Li X,Moresco EMY,Beutler B

更新日期：2020-08-18 00:00:00

abstract：BACKGROUND:The inflammation of atopic eczema (AE) is orchestrated not only by T cells predominantly but also B cells, eosinophils and dendritic cells. Recently, a role of invariant natural killer T (NKT) cells has been reported in bronchial asthma and allergy. Natural killer T cells express a restricted repertoire of T...

journal_title：Allergy

authors： Simon D,Kozlowski E,Simon H

更新日期：2009-11-01 00:00:00

abstract：:Although allergen immunotherapy (IT) has been shown to modulate allergic hypersensitivities, its efficacy is limited. Recently, in various models of experimental allergy, a number of reagents which we have termed immunostimulatory DNA-based therapeutics have proven highly effective in both the prevention and reversal ...

journal_title：Allergy

authors： Horner AA,Takabaysahi K,Zubeldia JM,Raz E

更新日期：2002-01-01 00:00:00

abstract：:House-dust mites are a major source of allergens. Beds are often heavily infested. It is conceivable that, during the winter period in temperate climates, the ambient indoor air is too dry for their survival, but that mites can still survive in beds where the humidity is raised when the bed is occupied. To investigate...

journal_title：Allergy

authors： de Boer R,Kuller K

更新日期：1997-03-01 00:00:00

abstract：:The ability of common environmental allergens to stimulate IgE responses and thus to produce allergic diseases has tended to overshadow the fact that helminthic parasites are possibly the most potent inducers of this immunoglobulin that exists in nature. Although it has been well established that during these infectio...

journal_title：Allergy

authors： Mingomataj EC,Xhixha F,Gjata E

更新日期：2006-04-01 00:00:00

abstract：:The association between food allergy and celiac disease (CD) is still to be clarified. We screened for CD 319 patients with severe food allergy (IgE > 85 kU/l against food proteins and a history of severe allergic reactions) who underwent specific food oral immunotherapy (OIT), together with 128 children with mild all...

journal_title：Allergy

authors： Pillon R,Ziberna F,Badina L,Ventura A,Longo G,Quaglia S,De Leo L,Vatta S,Martelossi S,Patano G,Not T,Berti I

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Whereas recent studies underlie the fundamental importance of the CC chemokine receptor 3 (CCR3) for the recruitment of eosinophils in allergic diseases, controversial data exist about the relevance of CCR1 on eosinophils. Therefore, the purpose of this study was to investigate the expression and regulation ...

journal_title：Allergy

authors： Elsner J,Dulkys Y,Gupta S,Escher SE,Forssmann WG,Kapp A,Forssmann U

更新日期：2005-11-01 00:00:00

abstract：:In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...

journal_title：Allergy

authors： Dorsch W,Ring J

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Endogenous histamine-releasing factors (HRFs) are involved in 30-60% of patients with chronic urticaria (CU). Evidence for their existence comes from in vivo studies of autoreactivity with the autologous serum skin test (ASST), in vitro immunoassays demonstrating autoantibodies against the immunoglobulin E (...

journal_title：Allergy

authors： Platzer MH,Grattan CE,Poulsen LK,Skov PS

更新日期：2005-09-01 00:00:00

abstract：:Sleep is fundamental for physical and mental health as well as daytime performance and represents a crucial aspect in the personal representations of well-being. Sleep disturbances in patients with chronic disorders constitute a factor that contributes to exacerbate symptoms, complicate management, and affect mood and...

journal_title：Allergy

authors： Baiardini I,Braido F,Cauglia S,Canonica GW

更新日期：2006-11-01 00:00:00

abstract：:The effect of interleukin-3 (IL-3) on histamine release from cord and adult blood basophils were evaluated. Leukocyte suspensions, obtained from adult patients with respiratory allergy (n = 15), normal adult subjects (n = 15), and neonates with (n = 15) and without (n = 19) atopic disposition, were stimulated with ant...

journal_title：Allergy

authors： Miadonna A,Salmaso C,Marco MP,Pugni L,Milazzo N,Tedeschi A,Marini A

更新日期：1997-10-01 00:00:00

abstract：:Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes, thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to asthma, allergies, and allied diseases. Prostaglandins and leukotrienes are the most studied eicosanoids and established inducers of air...

journal_title：Allergy

authors： Sokolowska M,Rovati GE,Diamant Z,Untersmayr E,Schwarze J,Lukasik Z,Sava F,Angelina A,Palomares O,Akdis CA,O'Mahony L,Sanak M,Dahlen SE,Woszczek G

更新日期：2021-01-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are responsible for 21-25% of reported adverse drug events which include immunological and nonimmunological hypersensitivity reactions. This study presents up-to-date information on pathomechanisms, clinical spectrum, diagnostic tools and management of hypersensitivity rea...

journal_title：Allergy

authors： Kowalski ML,Makowska JS,Blanca M,Bavbek S,Bochenek G,Bousquet J,Bousquet P,Celik G,Demoly P,Gomes ER,Niżankowska-Mogilnicka E,Romano A,Sanchez-Borges M,Sanz M,Torres MJ,De Weck A,Szczeklik A,Brockow K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Multiple drug hypersensitivity syndrome (MDH) is used to describe persons with a drug hypersensitivity reaction (DHR) to at least two chemically unrelated drugs, confirmed by skin test or in vitro assay. METHODS:Medical records of 25 patients with MDH, tested and confirmed at our allergy division, were retr...

journal_title：Allergy

authors： Jörg L,Yerly D,Helbling A,Pichler W

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The diagnosis of allergic reactions to drugs is difficult. Most skin tests are not standardized, and in vitro tests are needed to avoid provocation tests. Cross-linking of IgE on basophils is known to cause the release of both cysteinyl leukotriene (Cys-LT) and histamine. We aimed to evaluate the diagnostic ...

journal_title：Allergy

authors： Lebel B,Messaad D,Kvedariene V,Rongier M,Bousquet J,Demoly P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:To date, there has been no reliable in vitro test to either diagnose or differentiate nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD). The aim of the present study was to develop and validate an artificial neural network (ANN) for the prediction of N-ERD in patients with a...

journal_title：Allergy

authors： Tyrak KE,Pajdzik K,Konduracka E,Ćmiel A,Jakieła B,Celejewska-Wójcik N,Trąd G,Kot A,Urbańska A,Zabiegło E,Kacorzyk R,Kupryś-Lipińska I,Oleś K,Kuna P,Sanak M,Mastalerz L

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:There has been a world-wide increase in the prevalence of atopic diseases. These atopic diseases, including asthma, allergic rhinoconjunctivitis and atopic eczema/dermatitis, are common in childhood and create a challenge of management for physicians and parents. METHODS:MEDLINE was searched for articles re...

journal_title：Allergy

authors： O'Connell EJ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Anaphylaxis to insect venom (Hymenoptera) is most severe in patients with mastocytosis and may even lead to death. However, not all patients with mastocytosis suffer from anaphylaxis. The aim of the study was to analyze differences in gene expression between patients with indolent systemic mastocytosis (ISM)...

journal_title：Allergy

authors： Niedoszytko M,Bruinenberg M,van Doormaal JJ,de Monchy JG,Nedoszytko B,Koppelman GH,Nawijn MC,Wijmenga C,Jassem E,Elberink JN

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Immune-modulation such as tolerance induction appears to be an upcoming concept to prevent development of atopic diseases. Pregnancy might present a critical period for preventing allergic sensitization of the progeny. We investigated the effect of maternal allergen exposures during pregnancy on allergen-ind...

journal_title：Allergy

authors： Gerhold K,Avagyan A,Reichert E,Seib C,Van DV,Luger EO,Hutloff A,Hamelmann E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:With the current increasing incidence of allergies worldwide, new treatments showing efficacy and long term safety are needed for chronic conditions such as persistent allergic rhinitis (PER). New generation H1-antihistamines have demonstrated anti-allergic properties, which could possibly enhance their effe...

journal_title：Allergy

authors： Fantin S,Maspero J,Bisbal C,Agache I,Donado E,Borja J,Mola O,Izquierdo I,international Rupatadine study group.

更新日期：2008-07-01 00:00:00

abstract：:Exposure to natural rubber latex (NRL) medical gloves poses risks to patients sensitized to NRL and to users of protective gloves. Previous studies have shown that extractable allergen levels of the gloves vary widely. Since most of the available laboratory methods of NRL allergen measurement lack adequate validation,...

journal_title：Allergy

authors： Palosuo T,Mäkinen-Kiljunen S,Alenius H,Reunala T,Yip E,Turjanmaa K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the preventive potential ...

journal_title：Allergy

authors： Kratzer B,Köhler C,Hofer S,Smole U,Trapin D,Iturri J,Pum D,Kienzl P,Elbe-Bürger A,Gattinger P,Mittermann I,Linhart B,Gadermaier G,Jahn-Schmid B,Neunkirchner A,Valenta R,Pickl WF

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. OBJECTIVES:To investigate the role of RV infections in preschool asthma: (i) susceptibility factors, (ii) clinical cou...

journal_title：Allergy

authors： Jartti T,Liimatainen U,Xepapadaki P,Vahlberg T,Bachert C,Finotto S,Kowalski ML,Sobanska A,Lukkarinen H,Pasioti M,Vuorinen T,Zhang N,Zimmermann T,Papadopoulos NG

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Polcalcins are pollen-specific allergens with two EF-hand calcium-binding sites that exhibit strong cross-reactivity. Our objective was to isolate and express the cDNA coding of the EF-hand calcium-binding allergen from lilac pollen and to study cross-reactivity with other polcalcins from related and nonrela...

journal_title：Allergy

authors： Ledesma A,Barderas R,Westritschnig K,Quiralte J,Pascual CY,Valenta R,Villalba M,Rodríguez R

更新日期：2006-04-01 00:00:00

abstract：UNLABELLED:Aspirin-induced asthma (AIA) is a clinical syndrome characterized by acute airway reaction to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS). The most recent etiological hypothesises is that an overexpression of the enzyme LTC(4) synthase occurs in AIA, with the consequent production of sulf...

journal_title：Allergy

authors： Micheletto C,Tognella S,Visconti M,Pomari C,Trevisan F,Dal Negro RW

更新日期：2004-03-01 00:00:00