Comparision of two-flow cytometry methods for basophil degranulation in patients sensitized to grass pollen.

abstract：BACKGROUND:Atopic eczema/dermatitis syndrome (AEDS) patients display immunoglobulin E (IgE) reactivity to several antigens, e.g. saprophytic yeasts as Malassezia furfur. AEDS patients also show IgE autoreactivity towards cells of their own tissue including epidermis. PURPOSE OF THE STUDY:The aim of this study was to i...

journal_title：Allergy

authors： Kortekangas-Savolainen O,Peltonen S,Pummi K,Kalimo K,Savolainen J

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Daily intensive exercise by elite athletes can result in exercise-induced asthma especially in elite swimmers and this may be linked to epithelial damage. OBJECTIVE:To study airway epithelial damage and release of damage-associated molecular patterns (DAMPs) after intensive exercise in elite athletes and co...

journal_title：Allergy

authors： Seys SF,Hox V,Van Gerven L,Dilissen E,Marijsse G,Peeters E,Dekimpe E,Kasran A,Aertgeerts S,Troosters T,Vanbelle V,Peers K,Ceuppens JL,Hellings PW,Dupont LJ,Bullens DM

更新日期：2015-02-01 00:00:00

abstract：:A study was performed in 43 workers exposed to methyltetrahydrophthalic anhydride (MTHPA) used as a hardener in an epoxy resin system. Ten workers sensitized to MTHPA (group SS; presence of serum IgE antibodies against a conjugate of MTHPA and human serum albumin (HSA) detected by RAST) had significantly higher levels...

journal_title：Allergy

authors： Nielsen J,Welinder H,Bensryd I,Andersson P,Skerfving S

更新日期：1994-04-01 00:00:00

abstract：:There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospe...

journal_title：Allergy

authors： Romano A,Gaeta F,Valluzzi RL,Zaffiro A,Caruso C,Quaratino D

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The cytokine network is thought to be essential in orchestrating airway inflammation in asthma. Although evidence has accumulated to suggest that atopic asthma is a Th2 disease, much less is known about nonatopic asthma. METHODS:We have compared the production of IL-4, IL-6, IFN-gamma, and TNF-alpha from pe...

journal_title：Allergy

authors： Bettiol J,Bartsch P,Louis R,De Groote D,Gevaerts Y,Louis E,Malaise M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Intradermal skin testing of the clinically important antibiotics ciprofloxacin, clarithromycin, and rifampicin in the case of suspected allergies to antibiotics is poorly standardized. For clinical practice, standardized procedures and protocols are desired. METHODS:Fifteen healthy volunteers were tested wi...

journal_title：Allergy

authors： Brož P,Harr T,Hecking C,Grize L,Scherer K,Jaeger KA,Bircher AJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed. METHODS:In 18 CRS patients without nasal polyps (CRSNP(-)), 35 CRSNP(+) patients and 22 patients with nasal structural abnormalities w...

journal_title：Allergy

authors： Kirsche H,Niederführ A,Deutschle T,Fuchs C,Riechelmann H

更新日期：2010-01-01 00:00:00

abstract：:In studies on atopic dermatitis (AD), different scoring systems are used to evaluate the severity of the disease. The objective of this study was to investigate agreement between observers in the assessment of the overall severity of AD, and interobserver variation in the assessment of severity of AD for each scoring ...

journal_title：Allergy

authors： Sprikkelman AB,Tupker RA,Burgerhof H,Schouten JP,Brand PL,Heymans HS,van Aalderen WM

更新日期：1997-09-01 00:00:00

abstract：UNLABELLED:We evaluated the ENEA System, a fully automated instrument for the measurement of specific IgE antibodies. The instrument dispenses sera and reagents, incubates, washes, and reads and prints results automatically. The "core" of the instrument is the reactive unit called ACE (Allergy Chamber Enzymatic), which...

journal_title：Allergy

authors： Plebani M,Faggian D,Borghesan F

更新日期：1995-03-01 00:00:00

abstract：:Histamine is a key mediator in the development of allergy symptoms, and oral H(1)-antihistamines are among the most widely used treatments for symptomatic relief in conditions such as allergic rhinitis and chronic urticaria. Ebastine is a second-generation antihistamine which has been shown to be an effective treatmen...

journal_title：Allergy

authors： Sastre J

更新日期：2008-12-01 00:00:00

abstract：:A modified basophil degranulation test proved reliable and easily reproducible in the investigation of 50 patients with allergies to bee and/or wasp stings. Its diagnostic value is comparable to that of the RAST and it is, in addition, simpler, quicker and cheaper. Its disadvantage is that it has to be performed withi...

journal_title：Allergy

authors： Mumcuoglu Y,Wortmann F

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Characterization of uncontrolled asthma burden in a natural treatment setting can influence treatment recommendations and clinical practice. The objective was to characterize and compare the economic burden of severe or difficult-to-treat asthma in uncontrolled and controlled patients. METHODS:Baseline pati...

journal_title：Allergy

authors： Sullivan SD,Rasouliyan L,Russo PA,Kamath T,Chipps BE,TENOR Study Group.

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The Coronavirus disease 2019 (COVID-19) has evolved as a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-)2. Allergists and other health care providers (HCPs) in the field of allergies and associated airway diseases are in the front line, taking care of ...

journal_title：Allergy

authors： Pfaar O,Klimek L,Jutel M,Akdis CA,Bousquet J,Breiteneder H,Chinthrajah S,Diamant Z,Eiwegger T,Fokkens WJ,Fritsch HW,Nadeau KC,O'Hehir RE,O'Mahony L,Rief W,Sampath V,Schedlowski M,Torres M,Traidl-Hoffmann C,Wang DY,

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Health-related quality of Life in patients with chronic urticaria is evaluated by mean of generic instruments or questionnaire designed for skin diseases. No disease-specific tool is now available for the assessment of chronic urticaria impact from patients' viewpoint. OBJECTIVE:The aim of our study is to d...

journal_title：Allergy

authors： Baiardini I,Pasquali M,Braido F,Fumagalli F,Guerra L,Compalati E,Braga M,Lombardi C,Fassio O,Canonica GW

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Although airway hyperresponsiveness (AHR) is a characteristic feature of asthma, it is also frequently present in allergic rhinitis (AR). However, the pathogenesis of AHR is unclear and the roles of cytokines in the airway have not been well established in AR. We sought to compare cytokine mRNA levels in the...

journal_title：Allergy

authors： Sohn SW,Lee HS,Park HW,Chang YS,Kim YK,Cho SH,Kim YY,Min KU

更新日期：2008-03-01 00:00:00

abstract：:B cells are essentially described for their capacity to produce antibodies ensuring anti-infectious immunity or deleterious responses in the case of autoimmunity or allergy. However, abundant data described their ability to restrain inflammation by diverse mechanisms. In allergy, some regulatory B-cell subsets produci...

journal_title：Allergy

authors： Braza F,Chesne J,Castagnet S,Magnan A,Brouard S

更新日期：2014-11-01 00:00:00

abstract：:A total of 105 "high-risk" infants born in 1988 were studied prospectively from birth to 18 months of age. The infants were recommended breastfeeding and/or hypoallergenic formula (Nutramigen or Profylac) combined with avoidance of solid foods during the first 6 months of life. All mothers had unrestricted diet. Avoid...

journal_title：Allergy

authors： Halken S,Høst A,Hansen LG,Osterballe O

更新日期：1992-10-01 00:00:00

abstract：:A total of 139 workers (71% of the available work force) in four grain elevator stores in Aalborg, Denmark, participated in a cross-sectional study on the prevalence of storage mite allergy among grain elevator workers. All underwent interview, prick test with a standard panel of allergens and the storage mites Acarus...

journal_title：Allergy

authors： Revsbech P,Andersen G

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Allergy has at least two components - a genetic predisposition referred to as atopy and the progress from an atopic state to clinically apparent disease. Peripheral blood monocytes are circulating myeloid precursors of antigen-presenting cells. The expression of cell surface proteins on monocytes may therefo...

journal_title：Allergy

authors： von Bubnoff D,Scheler M,Hinz T,Matz H,Koch S,Bieber T

更新日期：2004-09-01 00:00:00

abstract：RATIONALE:The European Position Paper on Sinusitis (EPOS) guidelines provide composite criteria to evaluate chronic rhinosinusitis (CRS) control, taking into consideration the severity of patients' symptoms, aspect of nasal mucosa and medical intake as parameters of CRS control. OBJECTIVES:To study the degree of CRS c...

journal_title：Allergy

authors： van der Veen J,Seys SF,Timmermans M,Levie P,Jorissen M,Fokkens WJ,Hellings PW

更新日期：2017-02-01 00:00:00

abstract：:In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily. The post-exercise percentage fall in FEV1 after SCG but not after ketotifen was significantly smaller than after placebo. A 1-week treatme...

journal_title：Allergy

authors： Tan WC,Lim TK

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Epidemiologic evidence indicates a relevant association between atopic dermatitis (AD) and attention-deficit/hyperactivity disorder (ADHD). Underlying mechanisms and ways to best identify subgroups of AD patients at risk for ADHD are poorly understood. AIMS OF THE STUDY:To compare sociodemographic, clinical...

journal_title：Allergy

authors： Schmitt J,Buske-Kirschbaum A,Tesch F,Trikojat K,Stephan V,Abraham S,Bauer A,Nemat K,Plessow F,Roessner V

更新日期：2018-03-01 00:00:00

abstract：:The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

journal_title：Allergy

authors： Wüthrich B

更新日期：1998-01-01 00:00:00

abstract：:The recent advances in the knowledge of the basic mechanisms underlying asthmatic inflammation have significantly contributed to the delineation of new therapeutic perspectives for asthma. There are currently three main approaches to the development of novel antiasthma treatments: 1) improvement in existing classes of...

journal_title：Allergy

authors： Pelaia G,Vatrella A,Calabrese C,Mazzarella G,Marsico SA

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Allergy diagnosis by determination of allergen-specific IgE is complicated by clinically irrelevant IgE, of which the most prominent example is IgE against cross-reactive carbohydrate determinants (CCDs) that occur on allergens from plants and insects. Therefore, CCDs cause numerous false-positive results. I...

journal_title：Allergy

authors： Holzweber F,Svehla E,Fellner W,Dalik T,Stubler S,Hemmer W,Altmann F

更新日期：2013-10-01 00:00:00

abstract：RATIONALE:Nasal allergen provocations may be useful in investigating the pathophysiology of allergic rhinitis and effects of treatments. OBJECTIVE:To use grass pollen nasal allergen challenge (NAC) to investigate the effects of allergen immunotherapy in a cross-sectional study. METHODS:We studied nasal and cutaneous ...

journal_title：Allergy

authors： Scadding GW,Eifan AO,Lao-Araya M,Penagos M,Poon SY,Steveling E,Yan R,Switzer A,Phippard D,Togias A,Shamji MH,Durham SR

更新日期：2015-06-01 00:00:00

abstract：:We challenged in a double-blind manner 46 pollen-allergic patients with 30 g of honey and another 32 patients with a placebo (30 g of syrup). Minor, mostly subjective, symptoms were seen in or reported by 26% of those challenged with honey and 41% of those challenged with placebo. In no case could the symptoms with ce...

journal_title：Allergy

authors： Kiistala R,Hannuksela M,Mäkinen-Kiljunen S,Niinimäki A,Haahtela T

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence, importance, and the order of frequency of IgE-mediated food allergens among infants and young children in Israel. STUDY DESIGN AND PATIENTS:In a cross-sectional study, the prevalence of IgE-mediated food allergy was investigated in 9070 infants and young children (0-2 years) who ...

journal_title：Allergy

authors： Dalal I,Binson I,Reifen R,Amitai Z,Shohat T,Rahmani S,Levine A,Ballin A,Somekh E

更新日期：2002-04-01 00:00:00