Full automation in allergy testing: measurement of specific IgE by the ENEA System.

abstract：:Monozygotic (MZ) twins discordant for complex diseases may help to find disease mechanisms that are not due to genetic variants. Intermittent allergic rhinitis (IAR) is an optimal disease model because it occurs at defined time points each year, owing to known external antigens. We hypothesized that MZ twins discordan...

journal_title：Allergy

authors： Sjogren AK,Barrenas F,Muraro A,Gustafsson M,Saetrom P,Wang H,Benson M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Allergic diseases have become a major public health problem in developed countries; yet, no reliable, safe and consistently effective treatment is available. DNA immunization has been shown to prevent and balance established allergic responses, however, the high dose of conventional DNA vaccines necessary fo...

journal_title：Allergy

authors： Scheiblhofer S,Gabler M,Leitner WW,Bauer R,Zoegg T,Ferreira F,Thalhamer J,Weiss R

更新日期：2006-07-01 00:00:00

abstract：:Basophil histamine release was studied in leukocyte suspensions from normal individuals and from patients allergic to house dust mite or birch pollen. Mediator release caused by IgE-mediated reactions was examined by stimulating the cells with anti-IgE or specific antigens, and the calcium ionophore A23187 was used fo...

journal_title：Allergy

authors： Clementsen P,Norn S,Kristensen KS,Hannoun C

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The atopy patch test (APT) is an in vivo model to study the induction of eczema by inhalant allergens. This study was designed to compare two commonly used APT methods. METHODS:In the first method, the allergen is dissolved in aqueous solution, which is applied on tape-stripped skin. In the second method, t...

journal_title：Allergy

authors： Oldhoff JM,Bihari IC,Knol EF,Bruijnzeel-Koomen CA,de Bruin-Weller MS

更新日期：2004-04-01 00:00:00

abstract：:Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-1 and IL-18, and is considered to be important for host defense against nematodes by inducing Th2 cytokine production via the IL-33 receptor. IL-33 receptor is a heterodimer of IL-1 receptor-like 1 (IL-1RL1; also called ST2, T1, Der4, an...

journal_title：Allergy

authors： Ohno T,Morita H,Arae K,Matsumoto K,Nakae S

更新日期：2012-10-01 00:00:00

abstract：:We studied 708 adolescents aged 15-17 years in the 9th grade of school in Imatra. Of the eligible population born in 1962 77% were included. All were skin prick tested with 16 extracts from two manufacturers with 12 common allergens, which included pollens, epithelia, mite, house dust and fish. At least one positive, ...

journal_title：Allergy

authors： Haahtela T,Björkstén F,Heiskala M,Suoniemi I

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:There is strong evidence that reduced exposures to microbial compounds triggering innate immune responses early in life are critical for the development of allergic illnesses. The underlying mechanisms remain unknown, but will include T-cell responses either along T helper type 1 (Th1)/Th2 pathways or via T ...

journal_title：Allergy

authors： Schaub B,Liu J,Schleich I,Höppler S,Sattler C,von Mutius E

更新日期：2008-11-01 00:00:00

abstract：:We investigated the relationship between residence in the neighbourhood of an aluminium smelter and the prevalence of atopy in schoolchildren (7-13 years of age). Atopy was assessed in 556 of the 620 participants by a skin prick test with eight common aeroallergens. The median exposures to sulphur dioxide and fluoride...

journal_title：Allergy

authors： Søyseth V,Kongerud J,Boe J

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Outside clinical trials, data on systemic reactions (SRs) due to allergen immunotherapy (AIT) are scarce. METHODS:A prospective, longitudinal, web-based survey of 'real-life' respiratory allergen immunotherapy (AIT) clinical practice was conducted in France, Germany and Spain. SRs were recorded and coded ac...

journal_title：Allergy

authors： Calderón MA,Vidal C,Rodríguez Del Río P,Just J,Pfaar O,Tabar AI,Sánchez-Machín I,Bubel P,Borja J,Eberle P,Reiber R,Bouvier M,Lepelliez A,Klimek L,Demoly P,EASSI Doctors' Group.

更新日期：2017-03-01 00:00:00

abstract：:The effect of interleukin-3 (IL-3) on histamine release from cord and adult blood basophils were evaluated. Leukocyte suspensions, obtained from adult patients with respiratory allergy (n = 15), normal adult subjects (n = 15), and neonates with (n = 15) and without (n = 19) atopic disposition, were stimulated with ant...

journal_title：Allergy

authors： Miadonna A,Salmaso C,Marco MP,Pugni L,Milazzo N,Tedeschi A,Marini A

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Adolescents have the highest risk for food allergy-related fatalities. Our main aim was to investigate the level of risk in everyday social situations as perceived by adolescents/young adults with peanut allergy, their families, and their friends. METHODS:The web-based 'Colours Of Risks' (COR) questionnaire...

journal_title：Allergy

authors： Stensgaard A,DunnGalvin A,Nielsen D,Munch M,Bindslev-Jensen C

更新日期：2017-07-01 00:00:00

abstract：:Phospholipase A2 (E.C. 3.1.1.4.) is a major allergen of honey bee venom. It exists in a glycosylated and an unglycosylated variant. Both forms and the glycopeptide isolated after exhaustive proteolytic digestion were tested in RAST and RAST inhibition studies. IgE from 11 of 14 bee venom allergy sera exhibited signifi...

journal_title：Allergy

authors： Weber A,Schröder H,Thalberg K,März L

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Recent studies have yielded heterogeneous results regarding the relationship between vitamin D and atopic conditions. The aim of this study was to investigate the association between serum vitamin D level and the prevalence of eczema in German children and adolescents. METHODS:Data were drawn for children a...

journal_title：Allergy

authors： Heimbeck I,Wjst M,Apfelbacher CJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The measurement of peak nasal inspiratory flow (PNIF) provides a simple, cheap, fast and readily available tool for determining the extent of nasal airway patency. However, there are questions regarding its repeatability when used to assess the degree of nasal obstruction in large populations. Therefore, thi...

journal_title：Allergy

authors： Starling-Schwanz R,Peake HL,Salome CM,Toelle BG,Ng KW,Marks GB,Lean ML,Rimmer SJ

更新日期：2005-06-01 00:00:00

abstract：:Taxonomy provides the basis for the identity of species, allowing the construction of keys and the reliable, reproducible identification of dust mites for ecologic purposes and other studies. Details are given of nomenclatorial conventions in taxonomy as applied to dust mites, and taxonomically problematic entities ar...

journal_title：Allergy

authors： Colloff MJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be defined. Established animal models assessing the role(s) of eosinophils as contributors and/or causative agents of disease have relied on congenitally deficient mice w...

journal_title：Allergy

authors： Jacobsen EA,Lesuer WE,Willetts L,Zellner KR,Mazzolini K,Antonios N,Beck B,Protheroe C,Ochkur SI,Colbert D,Lacy P,Moqbel R,Appleton J,Lee NA,Lee JJ

更新日期：2014-03-01 00:00:00

abstract：:ELISA is increasingly used to measure antibodies in new circumstances. Recently, it has been applied to the measurement of IgG subclass antibodies against common antigens in early childhood. These studies have raised concerns about the specificity of some of these assays. This paper details the results of experiments ...

journal_title：Allergy

authors： Ruiz RG,Price JF,Kemeny DM

更新日期：1994-10-01 00:00:00

abstract：:We describe two uncommon cases of oral allergy syndrome (OAS) after eating pistachio nuts (p.n.) in subjects (a 54-year-old man and a 3-year-old girl) with exclusive skin prick test (SPT) positivity to Parietaria (P.) and pistachio nut (p.n.) allergens. Serologic P.- and p.n.-specific IgE determinations were also carr...

journal_title：Allergy

authors： Liccardi G,Mistrello G,Noschese P,Falagiani P,D'Amato M,D'Amato G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Chitotriosidase (chitinase 1, Chit1), a major true chitinase in humans, is induced in childhood asthma and has been implicated in the pathogenesis of a variety of inflammatory and tissue remodeling responses. However, the role and the mechanisms that underlie these contributions to the diseases have not been...

journal_title：Allergy

authors： Hong JY,Kim M,Sol IS,Kim KW,Lee CM,Elias JA,Sohn MH,Lee CG

更新日期：2018-08-01 00:00:00

abstract：:Although nasal hyperreactivity (NHR) is a common feature in patients suffering from allergic and nonallergic rhinitis, it is widely neglected during history taking, underdiagnosed in the majority of patients with rhinitis and rhinosinusitis, not considered as an outcome parameter in clinical trials on novel treatments...

journal_title：Allergy

authors： Van Gerven L,Steelant B,Hellings PW

更新日期：2018-09-01 00:00:00

abstract：:In this study, we investigated the role of calcium and phospholipid-dependent protein kinase (protein kinase C, PKC) in the modulation of histamine release from human basophils. A novel and potent inhibitor of PKC, K-252a, inhibited the release of histamine induced by anti-IgE in a dose-dependent manner with ID50 (the...

journal_title：Allergy

authors： Morita Y,Takaishi T,Honda Z,Miyamoto T

更新日期：1988-02-01 00:00:00

abstract：:Respiratory epithelial mast cells are an expression of airway inflammatory processes. Nasal epithelial mast cells are known to be increased in allergic rhinitis and have now been examined in patients with nasal polyps. Metachromatic cell counts (mean +/- standard error) expressed as the sum of large mast cells, atypic...

journal_title：Allergy

authors： Ruhno J,Howie K,Anderson M,Andersson B,Vanzieleghem M,Hitch D,Lapp P,Denburg J,Dolovich J

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Strategies to prevent children from developing allergy have been elaborated on the basis of state-of-the-art reviews of the scientific literature regarding pets and allergies, building dampness and health, and building ventilation and health. A similar multidisciplinary review of infant feeding mode in relat...

journal_title：Allergy

authors： van Odijk J,Kull I,Borres MP,Brandtzaeg P,Edberg U,Hanson LA,Høst A,Kuitunen M,Olsen SF,Skerfving S,Sundell J,Wille S

更新日期：2003-09-01 00:00:00

abstract：:Climate therapy has been used for decades in the treatment of atopic dermatitis (AD), but evidence of its effectiveness has not yet been assessed systematically. A systematic literature search in Medline, Embase, and the Cochrane library was performed to identify all original studies concerning alpine climate treatmen...

journal_title：Allergy

authors： Fieten KB,Weststrate AC,van Zuuren EJ,Bruijnzeel-Koomen CA,Pasmans SG

更新日期：2015-01-01 00:00:00

abstract：:An egg protein, lysozyme, is a still unlabeled additive currently used in cheese preparation. Furthermore, the WHO-FAO committee considers it innocuous. However, 31% of children and 8% of adults with food allergies are allergic to eggs. This work aimed to determine the percentage of patients sensitized to lysozyme fro...

journal_title：Allergy

authors： Frémont S,Kanny G,Nicolas JP,Moneret-Vautrin DA

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Pollutants may affect pollen allergenicity and thus the prevalence of allergies. Although a few studies are available in literature, the connection between pollution and the allergenic potential of pollen has yet to be clearly defined. The objective of this study was to evaluate the effect of traffic-related...

journal_title：Allergy

authors： Ghiani A,Aina R,Asero R,Bellotto E,Citterio S

更新日期：2012-07-01 00:00:00

abstract：:For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25 degrees C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60 degrees C to kill the mites, and at 0, 6, 14, 21, and ...

journal_title：Allergy

authors： Kort HS,Kniest FM

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Venom immunotherapy (VIT) is regarded as an established and efficient treatment of Hymenoptera venom allergy. Different frequencies of side-effects have been reported in the literature, depending on the hyposensitization regimen (conventional outpatient programme, rush immunotherapy, ultra rush immunotherapy...

journal_title：Allergy

authors： Wenzel J,Meissner-Kraemer M,Bauer R,Bieber T,Gerdsen R

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Recurrent angioedema (RecA) is a frequent clinical problem characterized by suddenly occurring cutaneous and/or mucosal swellings. Depending on their location, RecA may be painful, hindering, disfiguring, or even life-threatening. The assessment of disease activity in affected patients is important to guide ...

journal_title：Allergy

authors： Weller K,Groffik A,Magerl M,Tohme N,Martus P,Krause K,Metz M,Staubach P,Maurer M

更新日期：2013-09-01 00:00:00