Abstract:
:The recent advances in the knowledge of the basic mechanisms underlying asthmatic inflammation have significantly contributed to the delineation of new therapeutic perspectives for asthma. There are currently three main approaches to the development of novel antiasthma treatments: 1) improvement in existing classes of drugs 2) identification of new compounds able to interfere with the complex network of proinflammatory mediators, cytokines, chemokines, and adhesion molecules involved in the pathogenesis of asthma 3) utilization of new forms of immunotherapy aimed at blocking the unbalanced Th2 response which characterizes the pathophysiology of asthma. Such a remarkable expansion in available therapeutic options will probably allow us, over the next decade, to treat asthma by more selectively targeting the pathogenetic events responsible for this widespread airway disease.
journal_name
Allergyjournal_title
Allergyauthors
Pelaia G,Vatrella A,Calabrese C,Mazzarella G,Marsico SAdoi
10.1034/j.1398-9995.2000.00510.xkeywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
60-6eissn
0105-4538issn
1398-9995journal_volume
55 Suppl 61pub_type
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