Advances and novel developments in environmental influences on the development of atopic diseases.

abstract：:In a double blind cross-over study 24 children suffering from acute bronchoconstriction were treated with either placebo, or terbutaline delivered by a pressurized aerosol with a tube spacer (TS), or salbutamol from a dry powder inhaler (Rotahaler = RO). Both active treatments resulted in a significant increase in FEV...

journal_title：Allergy

authors： Pedersen S

更新日期：1985-05-01 00:00:00

abstract：:We studied the effects of anti-asthmatic and anti-inflammatory drugs on antigen-induced bronchial anaphylactic reactions (BAR) in Sprague Dawley (SD) rats immunized with ovalbumin (OA) and alum. The animals were treated locally (intratracheal instillation (i.t.) or by aerosol) with terbutaline (TERB), disodium cromogl...

journal_title：Allergy

authors： Dahlbäck M,Brattsand R

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The nasal allergen challenge (NAC) is a useful tool for the diagnosis of allergic rhinitis (AR) and local allergic rhinitis (LAR) and might serve to design and monitor allergen immunotherapy. Nevertheless, data about its safety and reproducibility are scarce. OBJECTIVE:To investigate the safety and reproduc...

journal_title：Allergy

authors： Eguiluz-Gracia I,Testera-Montes A,González M,Pérez-Sánchez N,Ariza A,Salas M,Moreno-Aguilar C,Campo P,Torres MJ,Rondon C

更新日期：2019-06-01 00:00:00

abstract：:The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global social and economic impact, and high numbers of deaths. Many risk factors have been identified in the progression of COVID-19 into a severe and critical st...

journal_title：Allergy

authors： Gao YD,Ding M,Dong X,Zhang JJ,Kursat Azkur A,Azkur D,Gan H,Sun YL,Fu W,Li W,Liang HL,Cao YY,Yan Q,Cao C,Gao HY,Brüggen MC,van de Veen W,Sokolowska M,Akdis M,Akdis CA

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：:We studied the allergen composition in an extract of the storage mite Lepidoglyphus destructor. Monoclonal antibodies (mAbs) were raised against L. destructor by a standard hybridoma technique. In the subsequent screening, we concentrated on mAbs fulfilling three criteria. First, in ELISA, mAbs were assessed against a...

journal_title：Allergy

authors： Olsson S,Härfast B,Johansson SG,van Hage-Hamsten M

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Venom immunotherapy (VIT) is regarded as an established and efficient treatment of Hymenoptera venom allergy. Different frequencies of side-effects have been reported in the literature, depending on the hyposensitization regimen (conventional outpatient programme, rush immunotherapy, ultra rush immunotherapy...

journal_title：Allergy

authors： Wenzel J,Meissner-Kraemer M,Bauer R,Bieber T,Gerdsen R

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause. Indeed, recent evidence indicates that bacteria-derived extracellular vesicles (EV) appear to be an important causative agent of inflammatory diseases. Here, we ...

journal_title：Allergy

authors： Choi EB,Hong SW,Kim DK,Jeon SG,Kim KR,Cho SH,Gho YS,Jee YK,Kim YK

更新日期：2014-04-01 00:00:00

abstract：:Food allergies have become a significant heath burden as prevalence continues to rise, affecting 6%-13% of the global population. In the absence of drugs approved by regulatory agencies, the current standard of care remains avoidance of allergenic foods and management of acute allergic reactions with antihistamines an...

journal_title：Allergy

authors： Sampath V,Sindher SB,Alvarez Pinzon AM,Nadeau KC

更新日期：2020-06-01 00:00:00

abstract：:For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25 degrees C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60 degrees C to kill the mites, and at 0, 6, 14, 21, and ...

journal_title：Allergy

authors： Kort HS,Kniest FM

更新日期：1994-02-01 00:00:00

abstract：:Because humans breathe through the nose, the nasal mucosa becomes sensitized to inhalant allergens. Allergic rhinitis is, together with allergic conjunctivitis, the best example of a type I hypersensitivity reaction. It is an inflammation of the nasal mucosa induced by specific immune recognition of exogenous allergen...

journal_title：Allergy

authors： Van Cauwenberge PB

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Outside clinical trials, data on systemic reactions (SRs) due to allergen immunotherapy (AIT) are scarce. METHODS:A prospective, longitudinal, web-based survey of 'real-life' respiratory allergen immunotherapy (AIT) clinical practice was conducted in France, Germany and Spain. SRs were recorded and coded ac...

journal_title：Allergy

authors： Calderón MA,Vidal C,Rodríguez Del Río P,Just J,Pfaar O,Tabar AI,Sánchez-Machín I,Bubel P,Borja J,Eberle P,Reiber R,Bouvier M,Lepelliez A,Klimek L,Demoly P,EASSI Doctors' Group.

更新日期：2017-03-01 00:00:00

abstract：:The xenotransplantation research is driven by the increasing gap between the number of patients with end-stage organ failure on waiting lists for transplantation and the supply of allografts. The lack of success in developing suitable artificial organs for permanent treatment of organ failure has further strengthened ...

journal_title：Allergy

authors： Mollnes TE,Fiane AE

更新日期：2002-01-01 00:00:00

abstract：:Epicutaneous allergen-specific immunotherapy (EPIT) is proposed as an alternative route for allergen-specific immunotherapy (AIT). The induction of allergen-specific blocking IgG antibodies represents an important mechanism underlying AIT, but has not been investigated for EPIT. Here, we compared the induction of alle...

journal_title：Allergy

authors： Cabauatan CR,Campana R,Niespodziana K,Reinisch C,Lundberg U,Meinke A,Henning R,Neubauer A,Valenta R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Modulation of leukocyte recruitment through blocking of chemokine receptors has been proposed as an attractive therapeutic strategy. We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensit...

journal_title：Allergy

authors： Gupta S,Erdmann G,Schulz-Maronde S,Escher SE,Richter R,Forssmann WG,Elsner J,Forssmann U

更新日期：2008-10-01 00:00:00

abstract：:Type I allergy against some common microorganisms was investigated in 14 patients with AIDS and 11 human immunodeficiency virus (HIV) antibody-positive homosexual men, and in a control group consisting of 13 heterosexual men without HIV antibodies. Basophil histamine release technique was used as a sensitive method to...

journal_title：Allergy

authors： Pedersen M,Permin H,Jensen C,Stahl Skov P,Norn S,Faber V

更新日期：1987-05-01 00:00:00

abstract：:Occupational respiratory allergy to green coffee beans in coffee roastery workers is well established. I now report on a 50-year-old female atopic patient sensitized to the coffee plant used for indoor decoration. The symptoms were rhinitis and conjunctivitis on exposure to the plant. Investigation showed a positive s...

journal_title：Allergy

authors： Axelsson IG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Synthetic bedding has been associated with increased child wheeze and also higher allergen levels in several studies. We aimed to examine whether the association between synthetic bedding and adverse respiratory outcomes was more evident among skin-prick test (SPT) positive children. METHODS:A cross-section...

journal_title：Allergy

authors： Ponsonby AL,Gatenby P,Glasgow N,Mullins R,Hurwitz M,McDonald T

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Several studies showed that calcium-binding proteins have a fixed place in the spectrum of allergenic substances. Often the binding of a calcium ion induces conformational changes and affects immunoglobulin E-binding to the allergen. Hence, the quantitative characterization of the binding to calcium is of im...

journal_title：Allergy

authors： Hebenstreit D,Ferreira F

更新日期：2005-09-01 00:00:00

abstract：:Recent advances in experimental immunologic approaches to seasonal allergic rhinitis (SAR) have led to a shift in the concepts of its pathogenesis. The conventional view of SAR as a local response to inhaled allergens has largely given way to a new view of this disorder as a systemic condition with local tissue manife...

journal_title：Allergy

authors： Bachert C

更新日期：2001-01-01 00:00:00

abstract：:Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both activated human and mouse basophils can form extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins. In this report, we provide eviden...

journal_title：Allergy

authors： Yousefi S,Morshed M,Amini P,Stojkov D,Simon D,von Gunten S,Kaufmann T,Simon HU

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Early-life sensitization to indoor allergens predicts asthma development. The aim of this study was to compare allergen concentrations in day-care centers (DCC) with those in private homes. METHODS:Settled airborne dust was collected 4 times a year from 20 German DCC (620 samples) and from the homes of chil...

journal_title：Allergy

authors： Sander I,Lotz A,Neumann HD,Czibor C,Flagge A,Zahradnik E,Raulf M

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Fluorescence-labeled MHC class II/peptide tetramer complexes are considered as optimal tools to characterize allergen-specific CD4(+) T cells, but this technique is restricted to frequently expressed HLA class II molecules and knowledge of immunodominant epitopes. In contrast, allergen-stimulated proliferati...

journal_title：Allergy

authors： Van Hemelen D,Mahler V,Fischer G,Fae I,Reichl-Leb V,Pickl W,Jutel M,Smolinska S,Ebner C,Bohle B,Jahn-Schmid B

更新日期：2015-01-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:Twenty patients with severe or medium severe asthma were given atenolol (Atenol ICI-Pharma) and/or metoprolol (Seloken Hässle) for tachycardia, hyperkinetic tremor, arterial hypertension or symptoms of angina pectoris. These cardioselective beta-blocking drugs caused only a very slight decrease in PF values. There was...

journal_title：Allergy

authors： Carlson C,Järvinen KA

更新日期：1978-06-01 00:00:00

abstract：:Women's work has traditionally been considered less hazardous to health in comparison with men's work. The increased women's participation in the workforce has led to an increased attention to women's working conditions. Women and men are unequally represented in individual professions or sectors (horizontal segregati...

journal_title：Allergy

authors： Moscato G,Apfelbacher C,Brockow K,Eberle C,Genuneit J,Mortz CG,Quecchia C,Quirce S,Siracusa A,Tarlo SM,van Kampen V,Walusiak-Skorupa J,Raulf M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...

journal_title：Allergy

authors： Krause K,Spohr A,Zuberbier T,Church MK,Maurer M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Systemic allergic reactions are a risk for allergen immunotherapy that utilizes intact allergen preparations. We evaluated the safety, efficacy and immune mechanisms of short-course treatment with adjuvant-free Lolium perenne peptides (LPP) following a 6-week dose-escalation protocol. METHODS:In a prospecti...

journal_title：Allergy

authors： Mösges R,Koch AF,Raskopf E,Singh J,Shah-Hosseini K,Astvatsatourov A,Hauswald B,Yarin Y,Corazza F,Haazen L,Pirotton S,Allekotte S,Zadoyan G,Legon T,Durham SR,Shamji MH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The prevalence of allergic rhinoconjunctivitis has increased significantly over the past decades with grass pollen being a common trigger. The impact of allergy on patient's quality of life is substantial. AIM:To investigate the sustained effect on quality of life during the grass pollen season 1 year after...

journal_title：Allergy

authors： Frølund L,Durham SR,Calderon M,Emminger W,Andersen JS,Rask P,Dahl R

更新日期：2010-06-01 00:00:00