Heat-labile Escherichia coli toxin enhances the induction of allergen-specific IgG antibodies in epicutaneous patch vaccination.

abstract：:A variety of methods have been used to attempt to decrease the allergenicity of food products, with highly variable success. Limited knowledge of allergen and epitope structures and the factors governing their stability may explain this, and the ensuing need for an empirical approach. A combined effort from a processi...

journal_title：Allergy

authors： Soler-Rivas C,Wichers HJ

更新日期：2001-01-01 00:00:00

abstract：:Effects of a thromboxane synthetase inhibitor (OKY-046) and a cyclooxygenase inhibitor (indomethacin) on bronchial hyperresponsiveness induced by subthreshold concentration of aerosolized thromboxane A2 analogue (STA2) were investigated in anesthetized, artificially ventilated guinea pigs in order to examine the role ...

journal_title：Allergy

authors： Saito M,Fujimura M,Sakamoto S,Miyake Y,Shintani H,Yasui M,Matsuda T

更新日期：1992-04-01 00:00:00

abstract：:There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

journal_title：Allergy

authors： Panush RS,Veloso ML,Weiss S,Bielory L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Allergic sensitisation increases the risk for asthma development. In this prospective birth cohort (Environment and Childhood Asthma) study, we hypothesized that combining quantitative measures of IgE antibodies (Sigma-IgE) and Severity score of obstructive airways disease (OAD) at 2 years of age (Severity s...

journal_title：Allergy

authors： Lødrup Carlsen KC,Söderström L,Mowinckel P,Håland G,Pettersen M,Munthe Kaas MC,Devulapalli CS,Buchmann M,Ahlstedt S,Carlsen KH

更新日期：2010-09-01 00:00:00

abstract：:A one-day intensive educational course on allergy and immunology theory and diagnostic procedure significantly increased the competency of allergy and immunology fellows-in-training. ...

journal_title：Allergy

authors： Elizalde A,Perez EE,Sriaroon P,Nguyen D,Lockey RF,Dorsey MJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:The mechanisms of late asthmatic reactions provoked in atopic asthmatics by allergen-derived T-cell peptide epitopes remain unclear. Previous studies showed no changes in airway eosinophils or mast cell products after peptide challenge. In the present study our aim was to measure calcitonin gene-related pept...

journal_title：Allergy

authors： Kay AB,Ali FR,Heaney LG,Benyahia F,Soh CP,Renz H,Lee TH,Larché M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In this study, we examined T cell responses and HLA class II alleles in children with moderate-severe asthma. METHODS:Ninety-six children with moderate-severe asthma w...

journal_title：Allergy

authors： Knutsen AP,Vijay HM,Kumar V,Kariuki B,Santiago LA,Graff R,Wofford JD,Shah MR

更新日期：2010-11-01 00:00:00

abstract：:The efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double-blind, placebo-controlled trials (N = 1871) comparing the efficacy and safety of the SQ-standardized grass allergy immunotherapy...

journal_title：Allergy

authors： Nelson H,Blaiss M,Nolte H,Würtz SØ,Andersen JS,Durham SR

更新日期：2013-02-01 00:00:00

abstract：:This update aimed to review the new evidence available to support or refute prior Allergic Rhinitis and its Impact on Asthma (ARIA) statements. A Medline search of publications between 2000 and 2005 was conducted, with articles selected by experts. New evidence supports previous ARIA statements, such as: (i) allergic ...

journal_title：Allergy

authors： Cruz AA,Popov T,Pawankar R,Annesi-Maesano I,Fokkens W,Kemp J,Ohta K,Price D,Bousquet J,ARIA Initiative Scientific Committee.

更新日期：2007-01-01 00:00:00

abstract：:The association between food allergy and celiac disease (CD) is still to be clarified. We screened for CD 319 patients with severe food allergy (IgE > 85 kU/l against food proteins and a history of severe allergic reactions) who underwent specific food oral immunotherapy (OIT), together with 128 children with mild all...

journal_title：Allergy

authors： Pillon R,Ziberna F,Badina L,Ventura A,Longo G,Quaglia S,De Leo L,Vatta S,Martelossi S,Patano G,Not T,Berti I

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergen exposure time periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end...

journal_title：Allergy

authors： Karatzas K,Katsifarakis N,Riga M,Werchan B,Werchan M,Berger U,Pfaar O,Bergmann KC

更新日期：2018-09-01 00:00:00

abstract：:A study was performed in 43 workers exposed to methyltetrahydrophthalic anhydride (MTHPA) used as a hardener in an epoxy resin system. Ten workers sensitized to MTHPA (group SS; presence of serum IgE antibodies against a conjugate of MTHPA and human serum albumin (HSA) detected by RAST) had significantly higher levels...

journal_title：Allergy

authors： Nielsen J,Welinder H,Bensryd I,Andersson P,Skerfving S

更新日期：1994-04-01 00:00:00

abstract：:Viruses cause asthmatic exacerbations in schoolchildren. We tested the hypothesis that children who wheezed with viral respiratory tract infections secrete higher levels of the type 1 cytokine interferon-gamma (IFN-gamma) in the peripheral circulation than children who had never wheezed. Blood was taken from 13 childr...

journal_title：Allergy

authors： Leech SC,Price JF,Holmes BJ,Kemeny DM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Daily intensive exercise by elite athletes can result in exercise-induced asthma especially in elite swimmers and this may be linked to epithelial damage. OBJECTIVE:To study airway epithelial damage and release of damage-associated molecular patterns (DAMPs) after intensive exercise in elite athletes and co...

journal_title：Allergy

authors： Seys SF,Hox V,Van Gerven L,Dilissen E,Marijsse G,Peeters E,Dekimpe E,Kasran A,Aertgeerts S,Troosters T,Vanbelle V,Peers K,Ceuppens JL,Hellings PW,Dupont LJ,Bullens DM

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Few time-series studies, and none lasting longer than 4 years, have investigated the etiology of treated seasonal allergic rhinoconjunctivitis (SAR) on the basis of anti-allergic medication prescriptions. The aim of this article was to study the short-term relationship between pollen exposure and drug-treate...

journal_title：Allergy

authors： Caillaud DM,Martin S,Ségala C,Vidal P,Lecadet J,Pellier S,Rouzaire P,Tridon A,Evrard B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Workplace exposure to trimellitic anhydride (TMA) can elicit TMA-specific IgE (sIgE), which may lead to occupational asthma (OA). An occupational immunosurveillance program (OISP) has been implemented to monitor TMA exposure and immunologic outcomes. The purpose of this study was to determine whether TMA-spe...

journal_title：Allergy

authors： Ghosh D,Clay C,Bernstein JA

更新日期：2018-05-01 00:00:00

abstract：:This paper gives an overview of placebo-controlled studies of the effect of corticosteroid treatment on nasal blockage, based on objective measurements of nasal airway patency. A few studies of perennial rhinitis have indicated that pretreatment with an intranasal corticosteroid has a moderate effect on nasal hyperres...

journal_title：Allergy

authors： Mygind N,Dahl R,Nielsen LP,Hilberg O,Bjerke T

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. METHODS:We performed oral food challenges in 21 apple-allergic individuals with Elstar apples which had undergone gene ...

journal_title：Allergy

authors： Dubois AE,Pagliarani G,Brouwer RM,Kollen BJ,Dragsted LO,Eriksen FD,Callesen O,Gilissen LJ,Krens FA,Visser RG,Smulders MJ,Vlieg-Boerstra BJ,Flokstra-de Blok BJ,van de Weg WE

更新日期：2015-11-01 00:00:00

abstract：:The concentration of house-dust mites (Dermatophagoides pteronyssinus) was investigated in 96 Danish homes with one or more members suffering from asthma. The air-exchange rates, humidity, and temperature were measured in all the homes. A positive correlation was found between indoor air humidity and mite concentratio...

journal_title：Allergy

authors： Harving H,Korsgaard J,Dahl R

更新日期：1993-02-01 00:00:00

abstract：:Atopic dermatitis (AD) is a complex inflammatory disorder with multiple interactions between genetic, immune and external factors. The sum of external factors that an individual is exposed to throughout their lifetime is termed the exposome. The exposome spans multiple domains from population to molecular levels and, ...

journal_title：Allergy

authors： Stefanovic N,Flohr C,Irvine AD

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Effective methods of reducing dog allergen are required to help alleviate symptoms in asthmatic patients sensitized to dog who refuse to part with their pet. The aim of this study was to investigate the use of the high efficiency particulate air (HEPA) filter air cleaner to reduce airborne Can f 1 in homes w...

journal_title：Allergy

authors： Green R,Simpson A,Custovic A,Faragher B,Chapman M,Woodcock A

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappaB (NF-kappaB) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappaB suppression in dendritic cells by adenoviral gene transfer of a novel mutated ...

journal_title：Allergy

authors： Zhou LF,Zhang MS,Hu AH,Zhu Z,Yin KS

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The prevalence of allergic rhinoconjunctivitis has increased significantly over the past decades with grass pollen being a common trigger. The impact of allergy on patient's quality of life is substantial. AIM:To investigate the sustained effect on quality of life during the grass pollen season 1 year after...

journal_title：Allergy

authors： Frølund L,Durham SR,Calderon M,Emminger W,Andersen JS,Rask P,Dahl R

更新日期：2010-06-01 00:00:00

abstract：:The relationship between asthma and obesity appears to be quite complex. The aim of this study was to assess the effect of excess weight on asthma control evolution in a cohort of asthmatics. A prospective database was set up, which enrolled adult asthmatics with persistent (mild, moderate or severe) asthma. The contr...

journal_title：Allergy

authors： Saint-Pierre P,Bourdin A,Chanez P,Daures JP,Godard P

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to investigate whether uncontrolled asthma was associated with healthcare outcomes among Latin American patients with asthma. We used data from 2168 patients with asthma who participated in the 2011 Latin America Asthma Insights and Management (AIM) survey. Using Global Initiative for Ast...

journal_title：Allergy

authors： Gold LS,Montealegre F,Allen-Ramey FC,Jardim J,Smith N,Sansores R,Sullivan SD

更新日期：2013-11-01 00:00:00

abstract：:On rare occasions, exposure to methacrylates (MAs) may induce mucosal symptoms. Three patients, two dental laboratory workers and one hearing aid laboratory worker, are presented. All three had allergic contact dermatitis from MAs which disappeared after avoidance of contact with uncured MA compounds. Two of the patie...

journal_title：Allergy

authors： Estlander T,Kanerva L,Kari O,Jolanki R,Mölsä K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Histamine intolerance is thought to trigger manifold clinical symptoms after ingesting histamine-rich food due to reduced activity of diamine oxidase (DAO). No study has hitherto systematically assessed daily fluctuations of histamine levels and DAO activities in symptomatic patients. The aim of the study wa...

journal_title：Allergy

authors： Pinzer TC,Tietz E,Waldmann E,Schink M,Neurath MF,Zopf Y

更新日期：2018-04-01 00:00:00

abstract：:Basophils are evolutionarily conserved in many animal species, in spite of the fact that they account for <1% of peripheral blood leukocyte. This suggests that basophils have an indispensable and nonredundant role in vivo, even though they show some phenotypic similarity with tissue-resident mast cells. However, their...

journal_title：Allergy

authors： Karasuyama H,Obata K,Wada T,Tsujimura Y,Mukai K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:High microbial diversity in the environment has been associated with lower asthma risk, particularly in children exposed to farming. It remains unclear whether this effect operates through an altered microbiome of the mucosal surfaces of the airways. METHODS:DNA from mattress dust and nasal samples of 86 sc...

journal_title：Allergy

authors： Birzele LT,Depner M,Ege MJ,Engel M,Kublik S,Bernau C,Loss GJ,Genuneit J,Horak E,Schloter M,Braun-Fahrländer C,Danielewicz H,Heederik D,von Mutius E,Legatzki A

更新日期：2017-01-01 00:00:00