Environmental and mucosal microbiota and their role in childhood asthma.

abstract：BACKGROUND:Various techniques have been tried in an attempt to reduce allergen levels in homes. This study investigated the effect of dry heat on mite, cat, and dog allergens. METHODS:Samples (50 mg) of Dermatophagoides pteronyssinus and D. farinae cultures, and of house dust rich in the major cat and dog allergens Fe...

journal_title：Allergy

authors： Cain G,Elderfield AJ,Green R,Smillie FI,Chapman MD,Custovic A,Woodcock A

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils ...

journal_title：Allergy

authors： Fettelschoss-Gabriel A,Fettelschoss V,Olomski F,Birkmann K,Thoms F,Bühler M,Kummer M,Zeltins A,Kündig TM,Bachmann MF

更新日期：2019-03-01 00:00:00

abstract：:Mast cell degranulation, and the subsequent recruitment of infiltrating inflammatory cells, such as eosinophils, into the nasal mucosa has long been considered the most important model to explain allergic rhinitis. Several studies show a decrease in the number of eosinophils and possibly also mast cells during local c...

journal_title：Allergy

authors： Godthelp T,Holm AF,Blom H,Klein-Jan A,Rijntjes E,Fokkens WJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Little is known about the diagnostic approaches for immediate hypersensitivity reactions (IHRs) due to 5-nitroimidazole antibiotics. The aim was to evaluate the usefulness of in vivo tests and basophil activation test (BAT) for the diagnosis of IHRs due to metronidazole and ornidazole and to determine possib...

journal_title：Allergy

authors： Beyaz Ş,Akdeniz N,Yılmaz A,Demir S,Öztop N,Çolakoğlu B,Büyüköztürk S,Deniz G,Gelincik A

更新日期：2020-08-05 00:00:00

abstract：:B cells are essentially described for their capacity to produce antibodies ensuring anti-infectious immunity or deleterious responses in the case of autoimmunity or allergy. However, abundant data described their ability to restrain inflammation by diverse mechanisms. In allergy, some regulatory B-cell subsets produci...

journal_title：Allergy

authors： Braza F,Chesne J,Castagnet S,Magnan A,Brouard S

更新日期：2014-11-01 00:00:00

abstract：:Identification and characterization of risk and protective factors for allergy is important for developing strategies for prevention or treatment. The prevalence of allergy is clearly higher in affluent countries than in developing countries like, e.g. Africa. Especially in urban areas of developing countries, allergy...

journal_title：Allergy

authors： van Ree R,Yazdanbakhsh M

更新日期：2007-03-01 00:00:00

abstract：:The prick test is one of the most common medical methods for diagnosing allergies, and it has been carried out in a similar and laborious manner over many decades. In an attempt to standardize the reading of the test, many researchers have tried to automate the process of measuring the allergic reactions found by deve...

journal_title：Allergy

authors： Justo X,Díaz I,Gil JJ,Gastaminza G

更新日期：2016-08-01 00:00:00

abstract：:A modified basophil degranulation test proved reliable and easily reproducible in the investigation of 50 patients with allergies to bee and/or wasp stings. Its diagnostic value is comparable to that of the RAST and it is, in addition, simpler, quicker and cheaper. Its disadvantage is that it has to be performed withi...

journal_title：Allergy

authors： Mumcuoglu Y,Wortmann F

更新日期：1980-06-01 00:00:00

abstract：:The standard treatment of allergic rhinitis and asthma consists of topical corticosteroids administered intranasally and inhaled through the mouth. Although this therapy is highly effective, and side-effects are few and mild, it may be possible further to improve the therapeutic index and patient compliance with the t...

journal_title：Allergy

authors： Pedersen W,Hjuler I,Bisgaard H,Mygind N

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：:Six children and six adults were given a single dose of a sustained release theophylline preparation (Nuelin Retard) after an overnight fast and later after a standardized breakfast. Food significantly reduced the absorption rate of theophylline whereas the extent of absorption of theophylline was unaffected by food. ...

journal_title：Allergy

authors： Pedersen S,Moeller-Petersen J

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Anaphylaxis to insect venom (Hymenoptera) is most severe in patients with mastocytosis and may even lead to death. However, not all patients with mastocytosis suffer from anaphylaxis. The aim of the study was to analyze differences in gene expression between patients with indolent systemic mastocytosis (ISM)...

journal_title：Allergy

authors： Niedoszytko M,Bruinenberg M,van Doormaal JJ,de Monchy JG,Nedoszytko B,Koppelman GH,Nawijn MC,Wijmenga C,Jassem E,Elberink JN

更新日期：2011-05-01 00:00:00

abstract：:Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

journal_title：Allergy

authors： Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

更新日期：1988-08-01 00:00:00

abstract：:The clinical scoring systems of atopic dermatitis were analysed and compared. Some biological parameters that can correlate with the clinical score were also reviewed. After the definition of the disease based on validated clinical criteria, the second necessity was the availability of reliable severity scores to allo...

journal_title：Allergy

authors： Gelmetti C,Colonna C

更新日期：2004-08-01 00:00:00

abstract：:A 60-year-old man developed an anaphylactic reaction immediately after administration of intramuscular sodium cefuroxime. By means of oral controlled challenge, the reaction was reproduced with a smaller dose of cefuroxime axetil. Cross-reactivity with other betalactam antibiotics was ruled out by in vivo tests. This ...

journal_title：Allergy

authors： Marcos Bravo C,Luna Ortiz I,González Vázquez R

更新日期：1995-04-01 00:00:00

abstract：:The protective effect of terfenadine on inflammatory processes following the early phase of conjunctival provocation tests by specific allergen was assessed in 24 patients suffering from seasonal allergic rhinoconjunctivitis, in a single-blind, randomized, placebo-controlled, parallel-group study. Patients were random...

journal_title：Allergy

authors： Ciprandi G,Buscaglia S,Iudice A,Canonica GW

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinitis may be abnormally sensitive to stimulation of the ion channel transient receptor potential vanilloid-1 (TRPV1). AIM OF THE STUDY:To examine effects of various TRP ion channel activators on sensory symptoms in allergic rhinitis prior to and during seasonal allergen exposure. ...

journal_title：Allergy

authors： Alenmyr L,Högestätt ED,Zygmunt PM,Greiff L

更新日期：2009-05-01 00:00:00

abstract：:A group of nine patients with respiratory symptoms after nonspecific irritating stimuli, but without any IgE-mediated allergy or demonstrable bronchial obstruction, were referred to the asthma/allergy outpatient department for evaluation of suspected asthma. In order to find a provocation model and objectively assess ...

journal_title：Allergy

authors： Millqvist E,Löwhagen O

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:There are large differences in the prevalence of atopic disease between urban and rural areas of developing countries, without good explanation. Diet has been associated with atopic disease, but studies of specific nutrients are contradictory, cross-sectional studies often being unsupported by trials. We inv...

journal_title：Allergy

authors： Hooper R,Calvert J,Thompson RL,Deetlefs ME,Burney P

更新日期：2008-04-01 00:00:00

abstract：:Quantitative determinations of the inflammatory mediators in nasal secretions were performed and correlated with the objective nasal symptoms within 1 h after nasal allergen challenge (NAC). Twenty-six patients with seasonal allergic rhinitis were enrolled outside the pollen season. All measurements were performed bef...

journal_title：Allergy

authors： Wang D,Smitz J,Waterschoot S,Clement P

更新日期：1997-02-01 00:00:00

abstract：:The red cell-linked antigen-antiglobulin reaction (RCLAAR) with stearoyldextran-coated erythrocytes was used to characterize the immunoglobulin (Ig) classes and IgG subclasses of dextran reactive antibodies (DRA) in 27 dextran reactors (DR) and 96 on reactors (DNR). High titres of dextran reactive IgG were regularly f...

journal_title：Allergy

authors： Kraft D,Hedin H,Richter W,Scheiner O,Rumpold H,Devey ME

更新日期：1982-10-01 00:00:00

abstract：:To determine optimal conditions for allergen preservation, we investigated the influence of different stabilizing additives and of storage temperature on the allergen activity of apple protein preparations, obtained by extraction in phosphate buffer or by precipitation in diacetone alcohol and resolubilization in phos...

journal_title：Allergy

authors： Rudeschko O,Fahlbusch B,Henzgen M,Schlenvoigt G,Herrmann D,Vieths S,Jäger L

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Skin biopsies promote our understanding of atopic dermatitis/AD pathomechanisms in infants/toddlers with early-onset AD, but are not feasible in pediatric populations. Tape strips are an emerging, minimally invasive alternative, but global transcriptomic profiling in early pediatric AD is lacking. We aimed t...

journal_title：Allergy

authors： Pavel AB,Renert-Yuval Y,Wu J,Del Duca E,Diaz A,Lefferdink R,Fang MM,Canter T,Rangel SM,Zhang N,Krueger JG,Paller AS,Guttman-Yassky E

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Hen's egg (HE) allergy is a common disease in childhood. HE-specific serum IgE has been correlated with the outcome of oral food challenge tests, and diagnostic decision points have been described as helpful but still not sufficient to reduce the requirement for oral food challenges. The aim of the study was...

journal_title：Allergy

authors： Ahrens B,Lopes de Oliveira LC,Schulz G,Borres MP,Niggemann B,Wahn U,Beyer K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Allergic sensitisation increases the risk for asthma development. In this prospective birth cohort (Environment and Childhood Asthma) study, we hypothesized that combining quantitative measures of IgE antibodies (Sigma-IgE) and Severity score of obstructive airways disease (OAD) at 2 years of age (Severity s...

journal_title：Allergy

authors： Lødrup Carlsen KC,Söderström L,Mowinckel P,Håland G,Pettersen M,Munthe Kaas MC,Devulapalli CS,Buchmann M,Ahlstedt S,Carlsen KH

更新日期：2010-09-01 00:00:00

abstract：:In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...

journal_title：Allergy

authors： Dorsch W,Ring J

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Nasopharynx-associated lymphoid tissue (NALT) serves as an important inductive site for mucosal immunity in the upper respiratory tract. Despite its importance in the mucosal immune system, little is known regarding the role of NALT in airway allergic immune responses. We aimed to elucidate the role of NALT ...

journal_title：Allergy

authors： Kim DY,Fukuyama S,Nagatake T,Takamura K,Kong IG,Yokota Y,Lee CH,Kiyono H

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Variable airflow obstruction and airway hyperresponsiveness (AHR) are features of asthma, which are absent in nonasthmatic eosinophilic bronchitis (EB). Airway remodelling is characteristic of both conditions suggesting that remodelling and airway dysfunction are disassociated, but whether the airway geometr...

journal_title：Allergy

authors： Siddiqui S,Gupta S,Cruse G,Haldar P,Entwisle J,Mcdonald S,Whithers PJ,Hainsworth SV,Coxson HO,Brightling C

更新日期：2009-06-01 00:00:00

abstract：:Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA). Starting with the smallest ASA doses eliciting bronchial obstruction (threshold doses) we doubled the doses on subsequent days and finally achieved good tolerance of 600 mg ASA per day in 27 patien...

journal_title：Allergy

authors： Kowalski ML,Grzelewska-Rzymowska I,Rozniecki J,Szmidt M

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Intradermal skin testing of the clinically important antibiotics ciprofloxacin, clarithromycin, and rifampicin in the case of suspected allergies to antibiotics is poorly standardized. For clinical practice, standardized procedures and protocols are desired. METHODS:Fifteen healthy volunteers were tested wi...

journal_title：Allergy

authors： Brož P,Harr T,Hecking C,Grize L,Scherer K,Jaeger KA,Bircher AJ

更新日期：2012-05-01 00:00:00