Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics.

abstract：:This study was conducted to evaluate how bronchial responsiveness to direct and indirect stimuli relate to nitric oxide producing airway inflammation, and whether the relationship differs between atopic and nonatopic patients with various degrees of bronchial hyperresponsiveness and airway inflammation in a group of o...

journal_title：Allergy

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Sovijärvi AR

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Eosinophils develop from hematopoietic CD34(+) progenitor cells in the bone marrow (BM) under the influence of Interleukin-5 (IL-5). The primary source of IL-5 is T-lymphocytes, although other sources may exist. The aims of this study were to determine whether CD34(+) cells from human peripheral blood (PB) a...

journal_title：Allergy

authors： Bossios A,Sjöstrand M,Dahlborn AK,Samitas K,Malmhäll C,Gaga M,Lötvall J

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the occurrence of immunoglobulin E sensitization to common environmental allergens (atopy) and new allergic diseases among schoolchildren after starting school in a water-damaged school building. The staff and pupils of a Finnish elementary school with visible water da...

journal_title：Allergy

authors： Savilahti R,Uitti J,Roto P,Laippala P,Husman T

更新日期：2001-02-01 00:00:00

abstract：:A safe food supply is a legitimate expectation of consumers, which the food industry must meet. Allergic reactions to food are recognised as a significant public health problem. Protecting allergic consumers against such reactions, while minimising the impact of food allergy on their quality of life, poses a challenge...

journal_title：Allergy

authors： Crevel RW

更新日期：2001-01-01 00:00:00

abstract：:A simple microtiter assay for eosinophil activation is described. The assay used 1000-4000 eosinophils/microtiter well, and the design allows for a separate or simultaneous quantitative assessment of eosinophil adhesion to protein-coated microtiter wells and degranulation after stimulation with eosinophil-activating f...

journal_title：Allergy

authors： Reimert CM,Skov PS,Poulsen LK

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Little is known about the diagnostic approaches for immediate hypersensitivity reactions (IHRs) due to 5-nitroimidazole antibiotics. The aim was to evaluate the usefulness of in vivo tests and basophil activation test (BAT) for the diagnosis of IHRs due to metronidazole and ornidazole and to determine possib...

journal_title：Allergy

authors： Beyaz Ş,Akdeniz N,Yılmaz A,Demir S,Öztop N,Çolakoğlu B,Büyüköztürk S,Deniz G,Gelincik A

更新日期：2020-08-05 00:00:00

abstract：:Antibody-dependent, allergic autocytotoxicity (ACT) is an in vitro process through which WBC from patients and/or controls, passively sensitized with RAST positive serum, are damaged in the presence of corresponding food antigens. Studies among 13 patients, sensitive to cow milk, corn and wheat, and 13 asymptomatic co...

journal_title：Allergy

authors： Podleski WK

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Gliadins have been implicated in immunoglobulin E (IgE)-mediated allergy to ingested wheat and omega-5-gliadin is known to represent a major allergen in wheat-dependent exercise-induced anaphylaxis. Less known is whether omega-5-gliadin is a clinically relevant allergen in children with immediate allergy to ...

journal_title：Allergy

authors： Ito K,Futamura M,Borres MP,Takaoka Y,Dahlstrom J,Sakamoto T,Tanaka A,Kohno K,Matsuo H,Morita E

更新日期：2008-11-01 00:00:00

abstract：:For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25 degrees C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60 degrees C to kill the mites, and at 0, 6, 14, 21, and ...

journal_title：Allergy

authors： Kort HS,Kniest FM

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：:A young woman (26 years old), with gastrointestinal candidosis of 8 months duration, was hospitalized in our department to study her cell immunity. Five minutes after an id injection of PHA (bactophytohaemoagglutinin M, Difco, 1 mg), mix monilieae, mix tricophyton and PPD Berna, she showed an extensive wheal and flare...

journal_title：Allergy

authors： Schiavino D,Nucera E,Murzilli F,Schinco G,Papa G,Fais G,Patriarca G

更新日期：1992-04-01 00:00:00

abstract：:Recent advances in experimental immunologic approaches to seasonal allergic rhinitis (SAR) have led to a shift in the concepts of its pathogenesis. The conventional view of SAR as a local response to inhaled allergens has largely given way to a new view of this disorder as a systemic condition with local tissue manife...

journal_title：Allergy

authors： Bachert C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Artemisia annua is an important autumnal pollen allergen for seasonal allergic rhinitis (SAR) in northern China. To date, no study has investigated allergen immunotherapy with A annua. We aimed to investigate the efficacy and mechanisms underlying A annua-sublingual immunotherapy (SLIT). METHODS:This was a ...

journal_title：Allergy

authors： Lou H,Huang Y,Ouyang Y,Zhang Y,Xi L,Chu X,Wang Y,Wang C,Zhang L

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Mould-attributed symptoms have included features which overlap with unexplained syndromes such as sick building syndrome. OBJECTIVES:We describe questionnaire and chart review findings in patients following exposure to moulds which include Stachybotrys and compare responses with two control groups. METHODS...

journal_title：Allergy

authors： Al-Ahmad M,Manno M,Ng V,Ribeiro M,Liss GM,Tarlo SM

更新日期：2010-02-01 00:00:00

abstract：:In recent years, patients allergic to amoxicillin (AX) but with good tolerance of penicillin G (PG) have been described. It has been suggested that the epitope implicated in this type of sensitization might be located on the side-chain of the AX molecule. Thus, cross-reactivity between AX and cephadroxil (CEPH), a cep...

journal_title：Allergy

authors： Sastre J,Quijano LD,Novalbos A,Hernandez G,Cuesta J,de las Heras M,Lluch M,Fernandez M

更新日期：1996-06-01 00:00:00

abstract：:With an indirect immunofluorescence technique 77% of 96 patients with type I allergy and 40% of 20 patients with intrinsic bronchial asthma showed positive reactions for IgG anti-IgG antibodies in serum. They were present partly in an aggregated state not directly detectable before treatment with dithiothreitol. The a...

journal_title：Allergy

authors： Egeskjold EM,Permin H,Nielsen I,Sørensen HJ,Osterballe O,Kallerup HE

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Information about the influence of housing and occupant characteristics on mite allergen concentrations is crucial to determine which methods could be used to decrease exposure of susceptible subjects. OBJECTIVES:To identify housing and occupant characteristics that are associated with mite allergen concent...

journal_title：Allergy

authors： van Strien RT,Gehring U,Belanger K,Triche E,Gent J,Bracken MB,Leaderer BP

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a multifactorial and probably multigenic inflammatory disease of the upper airways, and has been associated with the HLA class II alleles DR4 and DR7. Here we investigated possible associations with other polymorphic susceptibility/resistance genes located within the major histocompatibili...

journal_title：Allergy

authors： Aron Y,Busson M,Polla BS,Dusser D,Lockhart A,Swierczewski E,Favatier F

更新日期：1999-02-01 00:00:00

abstract：:Application of strict diagnostic criteria to celiac disease has led to the realization that there is a wide clinical spectrum within this disease. Normally there are immune reactions to dietary proteins, particularly secretory antibodies of IgA class, low titers of serum antibody and specific down-regulation of IgE an...

journal_title：Allergy

authors： Ferguson A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:IgG to galactose-α-1,3-galactose (α-gal) are highly abundant natural antibodies (Ab) in humans. α-Gal-specific IgE Ab cause a special form of meat allergy characterized by severe systemic reactions 3-7 h after consumption of red meat. We investigated 20 patients who experienced such reactions and characteriz...

journal_title：Allergy

authors： Kollmann D,Nagl B,Ebner C,Emminger W,Wöhrl S,Kitzmüller C,Vrtala S,Mangold A,Ankersmit HJ,Bohle B

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Dupilumab, a fully human monoclonal antibody that binds IL-4Rα and inhibits signaling of both IL-4 and IL-13, has shown efficacy across multiple diseases with underlying type 2 signatures and is approved for treatment of asthma, atopic dermatitis, and chronic sinusitis with nasal polyposis. We sought to prov...

journal_title：Allergy

authors： Le Floc'h A,Allinne J,Nagashima K,Scott G,Birchard D,Asrat S,Bai Y,Lim WK,Martin J,Huang T,Potocky TB,Kim JH,Rafique A,Papadopoulos NJ,Stahl N,Yancopoulos GD,Murphy AJ,Sleeman MA,Orengo JM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Patients with a previous history of hypersensitivity reaction (HSR) to iodinated contrast media (ICM) are at high risk of the development of HSR to ICM. Many studies have tried to evaluate the diagnostic potential of skin tests in this population but have not yet reached a common conclusion. We investigated ...

journal_title：Allergy

authors： Yoon SH,Lee SY,Kang HR,Kim JY,Hahn S,Park CM,Chang YS,Goo JM,Cho SH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Nasopharynx-associated lymphoid tissue (NALT) serves as an important inductive site for mucosal immunity in the upper respiratory tract. Despite its importance in the mucosal immune system, little is known regarding the role of NALT in airway allergic immune responses. We aimed to elucidate the role of NALT ...

journal_title：Allergy

authors： Kim DY,Fukuyama S,Nagatake T,Takamura K,Kong IG,Yokota Y,Lee CH,Kiyono H

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:New routes of administering immunotherapy in respiratory allergy are being studied as an alternative to conventional injective immunotherapy. We carried out a study to evaluate the clinical efficacy and effects of sublingual immunotherapy in patients with Parietaria judaica-induced respiratory allergy. METH...

journal_title：Allergy

authors： Purello-D'Ambrosio F,Gangemi S,Isola S,La Motta N,Puccinelli P,Parmiani S,Savi E,Ricciardi L

更新日期：1999-09-01 00:00:00

abstract：:The nasal mucociliary clearance is an important defense mechanism of the upper respiratory tract. It is known to be influenced by many pharmacologic substances. We investigated the effects of three topical intranasal antiallergic formulations containing disodium cromoglycate (DNCG), dimethindene maleate (DMM), and aze...

journal_title：Allergy

authors： Alberty J,Stoll W

更新日期：1998-10-01 00:00:00

abstract：:The prick test is one of the most common medical methods for diagnosing allergies, and it has been carried out in a similar and laborious manner over many decades. In an attempt to standardize the reading of the test, many researchers have tried to automate the process of measuring the allergic reactions found by deve...

journal_title：Allergy

authors： Justo X,Díaz I,Gil JJ,Gastaminza G

更新日期：2016-08-01 00:00:00

abstract：:Mast cell degranulation, and the subsequent recruitment of infiltrating inflammatory cells, such as eosinophils, into the nasal mucosa has long been considered the most important model to explain allergic rhinitis. Several studies show a decrease in the number of eosinophils and possibly also mast cells during local c...

journal_title：Allergy

authors： Godthelp T,Holm AF,Blom H,Klein-Jan A,Rijntjes E,Fokkens WJ

更新日期：1995-01-01 00:00:00

abstract：:The concentration of house-dust mites (Dermatophagoides pteronyssinus) was investigated in 96 Danish homes with one or more members suffering from asthma. The air-exchange rates, humidity, and temperature were measured in all the homes. A positive correlation was found between indoor air humidity and mite concentratio...

journal_title：Allergy

authors： Harving H,Korsgaard J,Dahl R

更新日期：1993-02-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) occurs in up to one-third of the adult US population. Most affected individuals are either unaware of their condition or do not seek medical help, relying on nonprescription acid suppressants and antacids for relief. GERD, a common disorder of infancy, old age, and pregnancy, is ...

journal_title：Allergy

authors： Theodoropoulos DS,Lockey RF,Boyce HW Jr,Bukantz SC

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:In sublingual immunotherapy, optimal doses are a key factor for therapeutic outcomes. The aim of this study with tablets containing carbamylated monomeric house dust mite allergoids was to determine the most effective and safe dose. METHODS:In this double-blind, placebo-controlled dose-finding study, 131 pa...

journal_title：Allergy

authors： Hüser C,Dieterich P,Singh J,Shah-Hosseini K,Allekotte S,Lehmacher W,Compalati E,Mösges R

更新日期：2017-01-01 00:00:00