Gastroesophageal reflux and asthma: a review of pathogenesis, diagnosis, and therapy.

abstract：:All eight production workers from a small trout-processing factory were studied because of respiratory or rhinitis symptoms when working next to the automatic gutting machine. Seven of the eight had positive histamine provocation tests. Four patients had elevated total IgE levels while one had a slightly elevated eosi...

journal_title：Allergy

authors： Sherson D,Hansen I,Sigsgaard T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to investigate the role of SLPI in patients with allergic rhinitis. From this point of view, we also examined leukocyte elastase, alpha1-antitrypsin, and albumin. SLPI is an inhibitor of serine proteases such as leukocyte elastase, cathepsin G, and mast-cell chymase. Since chymase i...

journal_title：Allergy

authors： Westin U,Lundberg E,Wihl JA,Ohlsson K

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Recent evidence indicates that Staphylococcus aureus, one of the most important human pathogens, secretes vesicles into the extracellular milieu. OBJECTIVE:To evaluate whether inhalation of S. aureus-derived extracellular vesicles (EV) is causally related to the pathogenesis of inflammatory pulmonary diseas...

journal_title：Allergy

authors： Kim MR,Hong SW,Choi EB,Lee WH,Kim YS,Jeon SG,Jang MH,Gho YS,Kim YK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Olive tree (Olea europaea) pollen is an important cause of pollinosis in the countries of the Mediterranean area. OBJECTIVE:This work aimed to study the IgE-binding frequency of Ole e 1, Ole e 2, Ole e 3, Ole e 6 and Ole e 7 from O. europaea pollen in a large population of olive pollen-allergic patients. M...

journal_title：Allergy

authors： Quiralte J,Florido F,Arias de Saavedra JM,Gómez A,Sáenz de San Pedro B,González E,Rodríguez R

更新日期：2002-01-01 00:00:00

abstract：:This is the first report on inhalative and ingestive allergy to the common edible mushroom Boletus edulis (Be) (English, edible boletus; German, Steinpilz; French, bolet; Italian, porcino or boleto) belonging to the class Basidiomycetes. Four cases observed in our allergy unit are presented, showing different clinical...

journal_title：Allergy

authors： Torricelli R,Johansson SG,Wüthrich B

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The mechanisms of late asthmatic reactions provoked in atopic asthmatics by allergen-derived T-cell peptide epitopes remain unclear. Previous studies showed no changes in airway eosinophils or mast cell products after peptide challenge. In the present study our aim was to measure calcitonin gene-related pept...

journal_title：Allergy

authors： Kay AB,Ali FR,Heaney LG,Benyahia F,Soh CP,Renz H,Lee TH,Larché M

更新日期：2007-05-01 00:00:00

abstract：:Since the pharmacological treatment of allergic diseases is used in patients with alteration of the immune response due to atopy and possible concomitant infections, we have investigated the possible effects of such drugs as cromolyn, theophylline, ketotifen, oxatomide, astemizole, fenoterol, pirenzepine, and rosapros...

journal_title：Allergy

authors： Canonica GW,Ciprandi G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Previous observational studies have implied breastmilk fatty acid composition may play a role in the development of atopic eczema or atopic sensitization in breastfed infants and toddlers. However, studies investigating associations with wheeze and asthma in later childhood are scarce and did not account for...

journal_title：Allergy

authors： Logan CA,Brandt S,Wabitsch M,Brenner H,Wiens F,Stahl B,Marosvölgyi T,Decsi T,Rothenbacher D,Genuneit J

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Physicians typically rely heavily on self-reported symptoms to make a diagnosis of exercise-induced bronchoconstriction (EIB). However, in elite sport, respiratory symptoms have poor diagnostic value. In 2009, following a change in international sports regulations, all elite athletes suspected of asthma and/...

journal_title：Allergy

authors： Ansley L,Kippelen P,Dickinson J,Hull JH

更新日期：2012-03-01 00:00:00

abstract：:The relation between platelet counts (PCT) and IgE was studied in cord blood from 136 European newborns. PCT was significantly lower (P = 0.0014) when cord-IgE was superior to 1.20 IU/ml (n = 29; 245,000/microliter) than when it was inferior to this value (n = 107; 284,080/microliter) which resulted in a significant n...

journal_title：Allergy

authors： Magnusson CG,de Weck AL

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmin, initiating and propagating danger signals resulting from tissue injury or inflammatory stimuli. The contribution of this immune sensing pathway to the development of allergic and inflammatory responses is unkn...

journal_title：Allergy

authors： Rubić-Schneider T,Carballido-Perrig N,Regairaz C,Raad L,Jost S,Rauld C,Christen B,Wieczorek G,Kreutzer R,Dawson J,Lametschwandner G,Littlewood-Evans A,Carballido JM

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The general understanding is that a blood sample for analysis of immunoglobulin (Ig) E antibodies to an allergen suspected to cause an anaphylaxis cannot be drawn until several weeks after the reaction. As this is most unpractical, the changes in IgE antibody levels during anaphylaxis were studied to evaluat...

journal_title：Allergy

authors： Guttormsen AB,Johansson SG,Oman H,Wilhelmsen V,Nopp A

更新日期：2007-11-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:While total IgE measurements are often used in clinical practice, it is unclear how they should be interpreted for the diagnosis of allergic disorders. We studied whether total IgE may be used to rule out or predict sensitization and whether there are age or gender differences. METHODS:ROC curves were asses...

journal_title：Allergy

authors： Kerkhof M,Dubois AE,Postma DS,Schouten JP,de Monchy JG

更新日期：2003-09-01 00:00:00

abstract：:CD4+ T effector lymphocytes are distinguished in different subsets on the basis of their patterns of cytokine secretion. Th1 cells, thank to IFN-γ production, are responsible for cell-mediated immunity against intracellular pathogens, Th2 cells, through the production of IL-4, provide some degree of protection against...

journal_title：Allergy

authors： Cosmi L,Liotta F,Maggi E,Romagnani S,Annunziato F

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:It is currently believed that most fungal exposure occurs external to the home. AIMS:To enumerate the fungal flora of used synthetic and feather pillows and the dust vacuumed from them, in the UK. METHODS:10 pillows aged between 1.5 and >20 years in regular use were collected and quantitatively cultured fo...

journal_title：Allergy

authors： Woodcock AA,Steel N,Moore CB,Howard SJ,Custovic A,Denning DW

更新日期：2006-01-01 00:00:00

abstract：:Standardized bronchial allergen provocation with the same individual allergen dose was performed 3-9 times in 20 symptomless adult asthmatic patients at intervals of 1 week or more during 1/2-22 months in order to study variations in bronchial response. The immediate type reaction was recorded by monitoring FEV1, FVC,...

journal_title：Allergy

authors： Loẅhagen O,Lindholm NB

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Several studies have shown that allergy to natural rubber latex is associated with cross-reactivity to certain foods such as tomato and potato. The objective was to investigate the clinical and immunologic differences between a group of patients with clinical allergy to tomato and latex and another which had...

journal_title：Allergy

authors： Reche M,Pascual CY,Vicente J,Caballero T,Martín-Muñoz F,Sanchez S,Martín-Esteban M

更新日期：2001-12-01 00:00:00

abstract：:In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...

journal_title：Allergy

authors： Dorsch W,Ring J

更新日期：1984-01-01 00:00:00

abstract：:Cat flea sensitivity is considered one of the most important skin diseases in cats and dogs. Cat fleas, however, are also a growing allergen problem for humans. Cat flea-specific IgE antibodies were studied in serum samples from 70 patients with suspected cat allergy, using RAST-based techniques and the nitrocellulose...

journal_title：Allergy

authors： Rolfsen W,Schröder H,Tibell C,Tibell M

更新日期：1987-04-01 00:00:00

abstract：:Elements are vital in airway mucosal physiology and pathology, but their distribution and levels in the mucosa remain unclear. This study uses the state-of-the-art nuclear microscopy facility to map and quantify multiple elements in the histology sections of nasal mucosa from patients with nasal polyps or inverted pap...

journal_title：Allergy

authors： Ren MQ,Zhou YT,Chen HX,Li TY,Vajandar SK,Osipowicz T,Watt F,Li CW

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Adolescents have the highest risk for food allergy-related fatalities. Our main aim was to investigate the level of risk in everyday social situations as perceived by adolescents/young adults with peanut allergy, their families, and their friends. METHODS:The web-based 'Colours Of Risks' (COR) questionnaire...

journal_title：Allergy

authors： Stensgaard A,DunnGalvin A,Nielsen D,Munch M,Bindslev-Jensen C

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The cysteinyl leukotrienes (cysLTs) play a key role in the pathophysiology of asthma. In addition to functioning as potent bronchoconstrictors, cysLTs contribute to airway inflammation through eosinophil and neutrophil chemotaxis, plasma exudation, and mucus secretion. We tested the activity of the dual cysL...

journal_title：Allergy

authors： Gauvreau GM,Boulet LP,FitzGerald JM,Cockcroft DW,Davis BE,Leigh R,Tanaka M,Fourre JA,Tanaka M,Nabata T,O'Byrne PM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The inflammation of atopic eczema (AE) is orchestrated not only by T cells predominantly but also B cells, eosinophils and dendritic cells. Recently, a role of invariant natural killer T (NKT) cells has been reported in bronchial asthma and allergy. Natural killer T cells express a restricted repertoire of T...

journal_title：Allergy

authors： Simon D,Kozlowski E,Simon H

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils ...

journal_title：Allergy

authors： Fettelschoss-Gabriel A,Fettelschoss V,Olomski F,Birkmann K,Thoms F,Bühler M,Kummer M,Zeltins A,Kündig TM,Bachmann MF

更新日期：2019-03-01 00:00:00

abstract：:Occupational respiratory allergy to green coffee beans in coffee roastery workers is well established. I now report on a 50-year-old female atopic patient sensitized to the coffee plant used for indoor decoration. The symptoms were rhinitis and conjunctivitis on exposure to the plant. Investigation showed a positive s...

journal_title：Allergy

authors： Axelsson IG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Signal transducer and activator of transcription 1 (STAT1), an intracellular signal transducer and activator of transcription centrally involved in many inflammatory pathways, was recently suggested to play an important role in allergy related immune responses. AIM:Thus, we investigated the effect of polymo...

journal_title：Allergy

authors： Pinto LA,Steudemann L,Depner M,Klopp N,Illig T,Weiland SK,von Mutius E,Kabesch M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：:Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma. PubMed, Embase ...

journal_title：Allergy

authors： Agache I,Beltran J,Akdis C,Akdis M,Canelo-Aybar C,Canonica GW,Casale T,Chivato T,Corren J,Del Giacco S,Eiwegger T,Firinu D,Gern JE,Hamelmann E,Hanania N,Mäkelä M,Hernández-Martín I,Nair P,O'Mahony L,Papadopoulos NG

更新日期：2020-05-01 00:00:00

abstract：:Tiaramide hydrochloride (THC) is a new basic, non-steroidal, anti-flammatory drug. Its anti-anaphylactic action has been investigated using rat mast cells. It was found that THC exerts a strong inhibitory action on antigen-induced and compound 48/80-induced histamine release from rat peritoneal mast cells in a fluorom...

journal_title：Allergy

authors： Renoux ML,Weill BJ,Wallach D,Chwetzoff E

更新日期：1978-04-01 00:00:00