Cytodestructive mechanisms provoked by food antigens. II. Antibody-dependent, allergic autocytotoxicity.

abstract：BACKGROUND:The pollen-food syndrome (PFS) is an association of food allergies to fruits, nuts, and vegetables in patients with pollen allergy. Mal d 1, the major apple allergen, is one of the most commonly associated food allergens for birch pollen-allergic patients suffering from PFS. Although the reactions are due to...

journal_title：Allergy

authors： Klinglmayr E,Hauser M,Zimmermann F,Dissertori O,Lackner P,Wopfner N,Ferreira F,Wallner M

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Environmental factors, including the intrauterine environment, can influence the risk of allergy development. In the present study, we investigated whether lifestyle and parental allergen sensitization status are reflected at gene expression level in the intrauterine environment. METHODS:  mRNA expression o...

journal_title：Allergy

authors： Joerink M,Oortveld MA,Stenius F,Rindsjö E,Alm J,Scheynius A

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) may affect the expression of hundreds of genes in different cells and tissues from patients with intermittent allergic rhinitis (IAR). It is a formidable challenge to understand these complex changes by studying individual genes. In this study, we aimed to identify (i) pathways affected...

journal_title：Allergy

authors： Wang H,Chavali S,Mobini R,Muraro A,Barbon F,Boldrin D,Aberg N,Benson M

更新日期：2011-01-01 00:00:00

abstract：:Anaphylaxis is a growing paediatric clinical emergency that is difficult to diagnose because a consensus definition was lacking until recently. Many European countries have no specific guidelines for anaphylaxis. This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical g...

journal_title：Allergy

authors： Muraro A,Roberts G,Clark A,Eigenmann PA,Halken S,Lack G,Moneret-Vautrin A,Niggemann B,Rancé F,EAACI Task Force on Anaphylaxis in Children.

更新日期：2007-08-01 00:00:00

abstract：:Olea europaea (olive) pollen extract was prepared by aqueous extraction and characterized by biochemical and immunochemical methods. Two components, displaying respective mol. wt. of 17,000 and 19,000, were the most reactive allergens, being the doublet (designated Ole e I) recognized by most sera tested. The 19,000 m...

journal_title：Allergy

authors： De Cesare F,Pini C,Di Felice G,Caiaffa MF,Macchia L,Tursi A,Tinghino R,Palumbo S,Sallusto F,Federico R

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Epidemiologic evidence indicates a relevant association between atopic dermatitis (AD) and attention-deficit/hyperactivity disorder (ADHD). Underlying mechanisms and ways to best identify subgroups of AD patients at risk for ADHD are poorly understood. AIMS OF THE STUDY:To compare sociodemographic, clinical...

journal_title：Allergy

authors： Schmitt J,Buske-Kirschbaum A,Tesch F,Trikojat K,Stephan V,Abraham S,Bauer A,Nemat K,Plessow F,Roessner V

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The precise immunological mechanisms for the early clinical protection of venom immunotherapy (VIT) have not yet been explained. Our aim was to evaluate whether high-affinity IgE receptor (FcεRI) and the related basophil function have a role in the induction of short-term VIT protection. METHODS:We included...

journal_title：Allergy

authors： Čelesnik N,Vesel T,Rijavec M,Šilar M,Eržen R,Košnik M,Kloft Žitnik SE,Avčin T,Korošec P

更新日期：2012-12-01 00:00:00

abstract：:Administration of allergen-specific immunotherapy by the oral route, sublingual immunotherapy (SLIT), has been shown to be effective, with an improved safety profile compared with subcutaneous administration. However, the precise mechanisms underlying the induction of immune tolerance by SLIT remain unclear. Contact o...

journal_title：Allergy

authors： Akdis CA,Barlan IB,Bahceciler N,Akdis M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:In atopic individuals, exposure to allergens is followed by recruitment of blood eosinophils in the target tissue. We investigated whether allergen inhalation challenge could result in depletion of blood eosinophils overexpressing adhesion molecules involved in eosinophil migration. METHODS:Blood eosinophil...

journal_title：Allergy

authors： Lantero S,Spallarossa D,Silvestri M,Sabatini F,Scarso L,Crimi E,Rossi GA

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Allergic sensitisation increases the risk for asthma development. In this prospective birth cohort (Environment and Childhood Asthma) study, we hypothesized that combining quantitative measures of IgE antibodies (Sigma-IgE) and Severity score of obstructive airways disease (OAD) at 2 years of age (Severity s...

journal_title：Allergy

authors： Lødrup Carlsen KC,Söderström L,Mowinckel P,Håland G,Pettersen M,Munthe Kaas MC,Devulapalli CS,Buchmann M,Ahlstedt S,Carlsen KH

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Aspirin, a cyclo-oxygenase (COX)-1 and COX-2 inhibitor, is the antiplatelet drug of choice to prevent serious vascular events. Adverse reactions to aspirin are frequent particularly among patients with asthma, chronic rhinosinusitis and nasal polyps. COX-1 inhibitors but not COX-2 inhibitors precipi...

journal_title：Allergy

authors： Fraj J,Valero A,Vives R,Pérez I,Borja J,Izquierdo I,Picado C

更新日期：2008-01-01 00:00:00

abstract：:A two-site immunometric assay based on monoclonal antibodies (mAb) was developed for the measurement of a 20-kDa major allergen of cow. The sensitivity of this assay was (BDA20) 1 ng/ml. It was used to measure airborne allergen concentrations in 10 Finnish cowsheds. The mean concentration of the BDA20 measured at two ...

journal_title：Allergy

authors： Ylönen J,Virtanen T,Rytkönen M,Mäntyjärvi R

更新日期：1994-10-01 00:00:00

abstract：:Phospholipase A2 (E.C. 3.1.1.4.) is a major allergen of honey bee venom. It exists in a glycosylated and an unglycosylated variant. Both forms and the glycopeptide isolated after exhaustive proteolytic digestion were tested in RAST and RAST inhibition studies. IgE from 11 of 14 bee venom allergy sera exhibited signifi...

journal_title：Allergy

authors： Weber A,Schröder H,Thalberg K,März L

更新日期：1987-08-01 00:00:00

abstract：:Although studies of families, inbred populations and twins have established that asthma has a hereditary basis, little evidence has shown that intrinsic asthma has an increased familial occurrence. To document this issue, we compared the prevalence of asthma in families of intrinsic asthmatics, extrinsic asthmatics an...

journal_title：Allergy

authors： Pirson F,Charpin D,Sansonetti M,Lanteaume A,Kulling G,Charpin J,Vervloet D

更新日期：1991-07-01 00:00:00

abstract：:Allergic rhinitis (AR) is a very common disease with over 600 million people (200 million of them with concomitant asthma) worldwide suffering from it. The majority of patients who seek medical advice are seen in primary care. Although there is a selection of guidelines focused on the management of AR, there is a pauc...

journal_title：Allergy

authors： Ryan D,van Weel C,Bousquet J,Toskala E,Ahlstedt S,Palkonen S,van den Nieuwenhof L,Zuberbier T,Wickman M,Fokkens W

更新日期：2008-08-01 00:00:00

abstract：:There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospe...

journal_title：Allergy

authors： Romano A,Gaeta F,Valluzzi RL,Zaffiro A,Caruso C,Quaratino D

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The worldwide increasing incidence of allergic diseases requires the development of new, efficient vaccination strategies, the only curative treatment with a long-lasting effect. Current allergen-specific immunotherapy protocols suffer from limited efficacy and a long treatment time. METHODS:We engineered m...

journal_title：Allergy

authors： Crameri R,Flückiger S,Daigle I,Kündig T,Rhyner C

更新日期：2007-02-01 00:00:00

abstract：:Respiratory epithelial mast cells are an expression of airway inflammatory processes. Nasal epithelial mast cells are known to be increased in allergic rhinitis and have now been examined in patients with nasal polyps. Metachromatic cell counts (mean +/- standard error) expressed as the sum of large mast cells, atypic...

journal_title：Allergy

authors： Ruhno J,Howie K,Anderson M,Andersson B,Vanzieleghem M,Hitch D,Lapp P,Denburg J,Dolovich J

更新日期：1990-07-01 00:00:00

abstract：:The efficacy and tolerability of intranasal azelastine (0.14 mg/nostril twice daily) and oral terfenadine (60 mg twice daily) were compared under double-blind conditions in two 6-week, multicenter, parallel-group studies, including 167 patients suffering from seasonal and 52 patients suffering from perennial allergic ...

journal_title：Allergy

authors： Gastpar H,Nolte D,Aurich R,Brendt P,Enzmann H,Giesemann G,Kunkel G,Petzold U,Renz W,Schata M

更新日期：1994-03-01 00:00:00

abstract：:In summary, beta 2-adrenergic agonists and corticosteroids can interact to produce beneficial effects on airway function. The regular use of short-acting, beta 2-adrenergic agonists as relief therapy is safe and effective; however, some degree of caution may be required with the use of very high doses. Long-acting bet...

journal_title：Allergy

authors： Chung KF

更新日期：1998-01-01 00:00:00

abstract：:Six children and six adults were given a single dose of a sustained release theophylline preparation (Nuelin Retard) after an overnight fast and later after a standardized breakfast. Food significantly reduced the absorption rate of theophylline whereas the extent of absorption of theophylline was unaffected by food. ...

journal_title：Allergy

authors： Pedersen S,Moeller-Petersen J

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:This paper reports a study on the concentrations of the pro-inflammatory cytokines IL-18 and IL-1beta in nasal secretions of allergic rhinitis patients in relation to ECP and nasal symptoms. METHODS:We measured IL-18 and IL-1beta concentrations using ELISA, and eosinophilic cationic protein (ECP) using the ...

journal_title：Allergy

authors： Verhaeghe B,Gevaert P,Holtappels G,Lukat KF,Lange B,Van Cauwenberge P,Bachert C

更新日期：2002-09-01 00:00:00

abstract：:Asthma deaths are uncommon, but have recently increased in some countries due to problems in the management of the disease. Morbidity rates show large variations, which can be attributed to differences in defining the disease, but also to genuine variations, with a trend towards less asthma in northern Europe. It has ...

journal_title：Allergy

authors： Charpin D,Vervloet D,Charpin J

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:The role of arachidonic acid metabolites in NSAID-induced hypersensitivity has been studied in depth for NSAID-exacerbated respiratory disease (NERD) and NSAID-exacerbated cutaneous disease (NECD). However, no information is available for NSAID-induced urticarial/angioedema (NIUA), despite it being the most ...

journal_title：Allergy

authors： Doña I,Jurado-Escobar R,Perkins JR,Ayuso P,Plaza-Serón MC,Pérez-Sánchez N,Campo P,Bogas-Herrera G,Bartra J,Torres MJ,Sanak M,Cornejo-García JA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Alkaline serine proteases from six prevalent airborne Penicillium and Aspergillus species have been identified as a group of major allergens (group 13). After entering human airways, the allergens are in initial contacts with respiratory epithelial cells. The purpose of this study is to investigate interacti...

journal_title：Allergy

authors： Tai HY,Tam MF,Chou H,Peng HJ,Su SN,Perng DW,Shen HD

更新日期：2006-03-01 00:00:00

abstract：:The connective tissue disorders (also called collagen vascular diseases) represent an heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs. The respiratory system may be involved in all its components: airways, vessels, parenchyma, pleura, res...

journal_title：Allergy

authors： Crestani B

更新日期：2005-06-01 00:00:00

abstract：:The aim of the study was to investigate whether topical application of a beta-2-adrenostimulant (fenoterol) on the mucous membrane has a clinically significant anti-allergic effect. Thirty-three patients with grass pollen hay fever completed the trial which was a double-blind, placebo-controlled cross-over design. Aft...

journal_title：Allergy

authors： Borum P,Larsen FS

更新日期：1987-02-01 00:00:00

abstract：:The treatment and management of ocular allergy (OA) remain a major concern for different specialties, including allergists, ophthalmologists, primary care physicians, rhinologists, pediatricians, dermatologists, clinical immunologists, and pharmacists. We performed a systematic review of all relevant publications in M...

journal_title：Allergy

authors： Leonardi A,Silva D,Perez Formigo D,Bozkurt B,Sharma V,Allegri P,Rondon C,Calder V,Ryan D,Kowalski ML,Delgado L,Doan S,Fauquert JL

更新日期：2019-09-01 00:00:00

abstract：:Delayed hypersensitivity to rubber chemicals is well known, but there are only a limited number of case reports on an immediate type of hypersensitivity inducing contact urticaria. We have recently seen several patients with rubber glove-induced contact urticaria who have had both positive skin prick tests and positiv...

journal_title：Allergy

authors： Axelsson JG,Johansson SG,Wrangsjö K

更新日期：1987-01-01 00:00:00