Abstract:
:Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both activated human and mouse basophils can form extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins. In this report, we provide evidence that, in spite of an apparent lack of phagocytic activity, basophils can kill bacteria through BET formation.
journal_name
Allergyjournal_title
Allergyauthors
Yousefi S,Morshed M,Amini P,Stojkov D,Simon D,von Gunten S,Kaufmann T,Simon HUdoi
10.1111/all.12662subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1184-8issue
9eissn
0105-4538issn
1398-9995journal_volume
70pub_type
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