Allergy to jackfruit: a novel example of Bet v 1-related food allergy.

Abstract:

BACKGROUND:Jackfruit allergy has been reported just once. It is unknown whether this food allergy is caused by direct sensitization or cross-sensitization to pollen allergens. OBJECTIVE:Establish whether jackfruit allergy is linked to birchpollen allergy. METHODS:Two jackfruit allergic patients and five patients with birchpollen-related apple allergy were recruited. Sensitization to pollen and plant foods was assessed by skin prick test (SPT), radio-allergosorbent test (RAST) and immunoblot. RAST analysis was performed for Bet v 1 and Mal d 1. Cross-reactivity was evaluated by RAST and immunoblot-inhibition. Biological activity of immunoglobulin E (IgE) was measured by basophil histamine release. Allergy to jackfruit was evaluated by double-blind placebo-controlled food challenge (DBPCFC) or open challenge (OC). RESULTS:In both patients DBPCFC confirmed the reported jackfruit allergy. SPT was 41 and 27 mm2 and specific IgE to jackfruit was 5.9 and 0.8 IU/ml, respectively. Immunoblot analysis revealed IgE reactivity at Mr of approximately 17 kDa. The Bet v 1-related nature of this allergen in jackfruit was demonstrated by RAST and immunoblot inhibition. To assess whether jackfruit allergy might be common in patients with combined birchpollen-fruit allergy, five such patients underwent an OC with jackfruit. All five had OA-like symptoms. CONCLUSIONS:Jackfruit allergy can be added to the list of birchpollen-related food allergies. Increased consumption of this fruit will result in a rise in allergic reactions.

journal_name

Allergy

journal_title

Allergy

authors

Bolhaar ST,Ree R,Bruijnzeel-Koomen CA,Knulst AC,Zuidmeer L

doi

10.1111/j.1398-9995.2004.00544.x

keywords:

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

1187-92

issue

11

eissn

0105-4538

issn

1398-9995

pii

ALL544

journal_volume

59

pub_type

杂志文章

相关文献

ALLERGY文献大全
  • Level of asthma control and healthcare utilization in Latin America.

    abstract::The purpose of this study was to investigate whether uncontrolled asthma was associated with healthcare outcomes among Latin American patients with asthma. We used data from 2168 patients with asthma who participated in the 2011 Latin America Asthma Insights and Management (AIM) survey. Using Global Initiative for Ast...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12237

    authors: Gold LS,Montealegre F,Allen-Ramey FC,Jardim J,Smith N,Sansores R,Sullivan SD

    更新日期:2013-11-01 00:00:00

  • Small-bowel capsule endoscopy in patients with gastrointestinal food allergy.

    abstract:BACKGROUND:Food allergy may present with a plethora of gastrointestinal and extraintestinal symptoms such as abdominal pain, diarrhea, cardiocirculatory symptoms, cutaneous reactions, or rhinitis. Macropathological lesions like lymphofollicular hyperplasia and erosive or ulcerative lesions have seldom been described in...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2011.02738.x

    authors: Hagel AF,de Rossi TM,Zopf Y,Lindner AS,Dauth W,Neurath MF,Raithel M

    更新日期:2012-02-01 00:00:00

  • Major allergens of date palm (Phoenix dactylifera L.) pollen. Identification of IgE-binding components by ELISA and immunoblot analysis.

    abstract::The IgE-binding components of date palm (Phoenix dactylifera L.) pollen were determined by ELISA and Western blotting in atopic patients in order to identify its major allergens. From a pool of previously identified allergenic fractions and sera from 15 skin-test-positive, atopic subjects, four components of 12, 14.4,...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1993.tb01107.x

    authors: Kwaasi AA,Parhar RS,Tipirneni P,Harfi H,al-Sedairy ST

    更新日期:1993-10-01 00:00:00

  • Farm animal feeders: another group affected by cereal flour asthma.

    abstract::Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1988.tb00909.x

    authors: Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

    更新日期:1988-08-01 00:00:00

  • The size of the disease relevant IgE antibody fraction in relation to 'total-IgE' predicts the efficacy of anti-IgE (Xolair) treatment.

    abstract:BACKGROUND:Some patients with allergic asthma treated with anti-IgE (Xolair) do not become symptom free. Better criteria for response assessment than allergy skin tests or IgE determination are needed. The impact of the size of the disease relevant allergen-specific IgE antibody fraction, i.e. the percentage of IgE ant...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2009.02051.x

    authors: Johansson SG,Nopp A,Oman H,Ankerst J,Cardell LO,Grönneberg R,Matsols H,Rudblad S,Strand V,Stålenheim G

    更新日期:2009-10-01 00:00:00

  • Breast milk fatty acid composition has a long-term effect on the risk of asthma, eczema, and sensitization.

    abstract:BACKGROUND:Levels of n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs in breast milk are associated with the development of allergic diseases up to school age. However, it is unknown whether this relationship persists when the child becomes older. We therefore studied the association between levels of n-3 PUFAs an...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12703

    authors: van Elten TM,van Rossem L,Wijga AH,Brunekreef B,de Jongste JC,Koppelman GH,Smit HA

    更新日期:2015-11-01 00:00:00

  • Lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level.

    abstract:BACKGROUND:Environmental factors, including the intrauterine environment, can influence the risk of allergy development. In the present study, we investigated whether lifestyle and parental allergen sensitization status are reflected at gene expression level in the intrauterine environment. METHODS:  mRNA expression o...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2010.02328.x

    authors: Joerink M,Oortveld MA,Stenius F,Rindsjö E,Alm J,Scheynius A

    更新日期:2010-10-01 00:00:00

  • Risks of allergic reactions to biotech proteins in foods: perception and reality.

    abstract::In recent years, significant attention has been paid to the use of biotechnology to improve the quality and quantity of the food supply due in part to the projected growth in the world population, plus limited options available for increasing the amount of land under cultivation. Alterations in the food supply induced...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.2005.00704.x

    authors: Lehrer SB,Bannon GA

    更新日期:2005-05-01 00:00:00

  • Regulatory functions of B cells in allergic diseases.

    abstract::B cells are essentially described for their capacity to produce antibodies ensuring anti-infectious immunity or deleterious responses in the case of autoimmunity or allergy. However, abundant data described their ability to restrain inflammation by diverse mechanisms. In allergy, some regulatory B-cell subsets produci...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.12490

    authors: Braza F,Chesne J,Castagnet S,Magnan A,Brouard S

    更新日期:2014-11-01 00:00:00

  • Storage mite allergy among bakers.

    abstract::Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bake...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1990.tb00484.x

    authors: Revsbech P,Dueholm M

    更新日期:1990-04-01 00:00:00

  • Management of ocular allergy.

    abstract::The treatment and management of ocular allergy (OA) remain a major concern for different specialties, including allergists, ophthalmologists, primary care physicians, rhinologists, pediatricians, dermatologists, clinical immunologists, and pharmacists. We performed a systematic review of all relevant publications in M...

    journal_title:Allergy

    pub_type: 杂志文章,meta分析

    doi:10.1111/all.13786

    authors: Leonardi A,Silva D,Perez Formigo D,Bozkurt B,Sharma V,Allegri P,Rondon C,Calder V,Ryan D,Kowalski ML,Delgado L,Doan S,Fauquert JL

    更新日期:2019-09-01 00:00:00

  • New European Academy of Allergy and Clinical Immunology definition on pollen season mirrors symptom load for grass and birch pollen-induced allergic rhinitis.

    abstract:BACKGROUND:The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergen exposure time periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13487

    authors: Karatzas K,Katsifarakis N,Riga M,Werchan B,Werchan M,Berger U,Pfaar O,Bergmann KC

    更新日期:2018-09-01 00:00:00

  • Clinical correlates of rhinovirus infection in preschool asthma.

    abstract:BACKGROUND:Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. OBJECTIVES:To investigate the role of RV infections in preschool asthma: (i) susceptibility factors, (ii) clinical cou...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.14479

    authors: Jartti T,Liimatainen U,Xepapadaki P,Vahlberg T,Bachert C,Finotto S,Kowalski ML,Sobanska A,Lukkarinen H,Pasioti M,Vuorinen T,Zhang N,Zimmermann T,Papadopoulos NG

    更新日期:2021-01-01 00:00:00

  • Longitudinal evaluation of bone mass in asthmatic children treated with inhaled beclomethasone dipropionate or cromolyn sodium.

    abstract::Inhaled corticosteroids are recommended as first-line therapy in patients with moderate to severe asthma. The use of these agents in the milder form of asthma is controversial because of their potential adverse effects, especially in growing children. We investigated 49 asthmatic children (38 treated with beclomethaso...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1998.tb03957.x

    authors: Martinati LC,Bertoldo F,Gasperi E,Fortunati P,Lo Cascio V,Boner AL

    更新日期:1998-07-01 00:00:00

  • Green, Yellow, and Red risk perception in everyday life - a communication tool.

    abstract:BACKGROUND:Adolescents have the highest risk for food allergy-related fatalities. Our main aim was to investigate the level of risk in everyday social situations as perceived by adolescents/young adults with peanut allergy, their families, and their friends. METHODS:The web-based 'Colours Of Risks' (COR) questionnaire...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13095

    authors: Stensgaard A,DunnGalvin A,Nielsen D,Munch M,Bindslev-Jensen C

    更新日期:2017-07-01 00:00:00

  • Chaperone patterns in vernal keratoconjunctivitis are distinctive of cell and Hsp type and are modified by inflammatory stimuli.

    abstract:BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12814

    authors: Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

    更新日期:2016-03-01 00:00:00

  • Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of local treatment with anti-asthmatic drugs.

    abstract::We studied the effects of anti-asthmatic and anti-inflammatory drugs on antigen-induced bronchial anaphylactic reactions (BAR) in Sprague Dawley (SD) rats immunized with ovalbumin (OA) and alum. The animals were treated locally (intratracheal instillation (i.t.) or by aerosol) with terbutaline (TERB), disodium cromogl...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1986.tb00352.x

    authors: Dahlbäck M,Brattsand R

    更新日期:1986-11-01 00:00:00

  • Omega 3 and 6 oils for primary prevention of allergic disease: systematic review and meta-analysis.

    abstract:BACKGROUND:There is conflicting evidence on the use of omega 3 and omega 6 supplementation for the prevention of allergic diseases. We conducted a systematic review evaluating the effectiveness of omega 3 and 6 oils for the primary prevention of sensitization and development of allergic disorders. METHODS:We searched ...

    journal_title:Allergy

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1398-9995.2009.02042.x

    authors: Anandan C,Nurmatov U,Sheikh A

    更新日期:2009-06-01 00:00:00

  • Purification and fine characterization of a major allergen from Olea europaea pollen extract.

    abstract::Olea europaea (olive) pollen extract was prepared by aqueous extraction and characterized by biochemical and immunochemical methods. Two components, displaying respective mol. wt. of 17,000 and 19,000, were the most reactive allergens, being the doublet (designated Ole e I) recognized by most sera tested. The 19,000 m...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1993.tb00724.x

    authors: De Cesare F,Pini C,Di Felice G,Caiaffa MF,Macchia L,Tursi A,Tinghino R,Palumbo S,Sallusto F,Federico R

    更新日期:1993-05-01 00:00:00

  • The future of specific immunotherapy: strategies and challenges for the next generation of allergy vaccines.

    abstract::: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2011.02644.x

    authors: Sørensen P

    更新日期:2011-07-01 00:00:00

  • Biological assays for interleukin 1 detection. Comparison of human T lymphocyte, murine thymocyte and NOB-1 assays.

    abstract::Various biological assays are used for qualitative and quantitative measurements of interleukin 1 (IL-1) in supernatants from cell cultures. The purpose of the present study was to compare the specificity and variability of three cellular IL-1 bioassays: the PHA co-stimulatory human T lymphocyte proliferation assay, t...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1991.tb00544.x

    authors: Remvig L,Vibe-Petersen J,Svenson M,Enk C,Bendtzen K

    更新日期:1991-01-01 00:00:00

  • Influence of hyposensitization on soluble interleukin-2 receptor, eosinophil cationic protein, in vitro lymphocyte proliferation, in vitro lymphocyte adhesion, and lymphocyte membrane markers in childhood asthma.

    abstract::Soluble interleukin-2 receptor (sIL-2R), eosinophil cationic protein (ECP), the lymphoproliferative response to house-dust mite (HDM), adhesion to human umbilical vein endothelial cells (HUVEC), and lymphocyte membrane markers were studied in three groups of children: healthy children, asthmatic children without hypos...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1994.tb00135.x

    authors: Moens MM,Van Bever HP,Stevens WJ,Mertens AV,Bridts CH,De Clerck LS

    更新日期:1994-09-01 00:00:00

  • Antiallergic actions of high topical doses of terbutaline in human nasal airways.

    abstract::It is debatable whether beta 2-receptor agonists produce antiallergic effects in human airways. This question has been addressed in the present study by examination of both mast-cell indices and the physiologic response to allergen challenge in human nasal airways. Twelve asymptomatic patients with seasonal allergic r...

    journal_title:Allergy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.1995.tb02494.x

    authors: Svensson C,Greiff L,Andersson M,Alkner U,Grönneberg R,Persson CG

    更新日期:1995-11-01 00:00:00

  • Regulatory T cells and type 2 innate lymphoid cell-dependent asthma.

    abstract::Group 2 innate lymphoid cells (ILC2s) are a recently identified group of cells with the potent capability to produce Th2-type cytokines such as interleukin (IL)-5 and IL-13. Several studies suggest that ILC2s play an important role in the development of allergic diseases and asthma. Activation of pulmonary ILC2s in mu...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.13139

    authors: Aron JL,Akbari O

    更新日期:2017-08-01 00:00:00

  • Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases.

    abstract:BACKGROUND AND AIMS:Aspirin, a cyclo-oxygenase (COX)-1 and COX-2 inhibitor, is the antiplatelet drug of choice to prevent serious vascular events. Adverse reactions to aspirin are frequent particularly among patients with asthma, chronic rhinosinusitis and nasal polyps. COX-1 inhibitors but not COX-2 inhibitors precipi...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2007.01473.x

    authors: Fraj J,Valero A,Vives R,Pérez I,Borja J,Izquierdo I,Picado C

    更新日期:2008-01-01 00:00:00

  • Monitoring of mite Dermatophagoides farinae allergen-specific IgG and IgG subclass distribution in patients on immunotherapy.

    abstract::House dust mite D. farinae and Der f II-specific IgG and IgG subclass responses were evaluated in 32 adults with perennial rhinitis undergoing immunotherapy for 1 year by means of IgG-RAST and ELISA. The ELISA method, which is based on subclass-specific monoclonal antibodies, could detect 0.5-1.5 ng/ml of specific ant...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1992.tb05092.x

    authors: Einarsson R,Dreborg S,Hammarström L,Löfkvist T,Smith CI,Svensson G

    更新日期:1992-04-01 00:00:00

  • Cord blood IgE. I. IgE screening in 2814 newborn children.

    abstract::Screening of total IgE in 2814 cord blood samples was analysed by Phadebas IgE PRIST in 2 1-year birth cohorts (1983-1984 and 1985-1986) in Denmark (n = 1189 + 1625). 48.6% of the sera contained less IgE than the detection limit 0.1 kU/l. Cord blood IgE values greater than or equal to 0.5 kU/l were regarded as elevate...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1992.tb02078.x

    authors: Hansen LG,Høst A,Halken S,Holmskov A,Husby S,Lassen LB,Storm K,Osterballe O

    更新日期:1992-08-01 00:00:00

  • Incidence and natural history of hen's egg allergy in the first 2 years of life-the EuroPrevall birth cohort study.

    abstract:BACKGROUND:Parents and health staff perceive hen's egg allergy (HEA) as a common food allergy in early childhood, but the true incidence is unclear because population-based studies with gold-standard diagnostic criteria are lacking. OBJECTIVE:To establish the incidence and course of challenge-confirmed HEA in children...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12801

    authors: Xepapadaki P,Fiocchi A,Grabenhenrich L,Roberts G,Grimshaw KE,Fiandor A,Larco JI,Sigurdardottir S,Clausen M,Papadopoulos NG,Dahdah L,Mackie A,Sprikkelman AB,Schoemaker AA,Dubakiene R,Butiene I,Kowalski ML,Zeman K,Gavri

    更新日期:2016-03-01 00:00:00

  • Sub-lethal exposure of cockroaches to boric acid pesticide contributes to increased Bla g 2 excretion.

    abstract:BACKGROUND:Several epidemiology studies have found an increase in the major cockroach allergen Bla g 2 with reported pesticide use. AIMS OF THE STUDY:Our aim was to investigate the effect on the excretion of Bla g 1 and Bla g 2 allergens by cockroaches exposed to sub-lethal doses of the pesticides, boric acid and hydr...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00814.x

    authors: Zhang YC,Perzanowski MS,Chew GL

    更新日期:2005-07-01 00:00:00

  • Mechanisms in adverse reactions to food. The joints and muscles.

    abstract::There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:

    authors: Panush RS,Veloso ML,Weiss S,Bielory L

    更新日期:1995-01-01 00:00:00