Risks of allergic reactions to biotech proteins in foods: perception and reality.

abstract：:The association between food allergy and celiac disease (CD) is still to be clarified. We screened for CD 319 patients with severe food allergy (IgE > 85 kU/l against food proteins and a history of severe allergic reactions) who underwent specific food oral immunotherapy (OIT), together with 128 children with mild all...

journal_title：Allergy

authors： Pillon R,Ziberna F,Badina L,Ventura A,Longo G,Quaglia S,De Leo L,Vatta S,Martelossi S,Patano G,Not T,Berti I

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Allergy has at least two components - a genetic predisposition referred to as atopy and the progress from an atopic state to clinically apparent disease. Peripheral blood monocytes are circulating myeloid precursors of antigen-presenting cells. The expression of cell surface proteins on monocytes may therefo...

journal_title：Allergy

authors： von Bubnoff D,Scheler M,Hinz T,Matz H,Koch S,Bieber T

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The role of arachidonic acid metabolites in NSAID-induced hypersensitivity has been studied in depth for NSAID-exacerbated respiratory disease (NERD) and NSAID-exacerbated cutaneous disease (NECD). However, no information is available for NSAID-induced urticarial/angioedema (NIUA), despite it being the most ...

journal_title：Allergy

authors： Doña I,Jurado-Escobar R,Perkins JR,Ayuso P,Plaza-Serón MC,Pérez-Sánchez N,Campo P,Bogas-Herrera G,Bartra J,Torres MJ,Sanak M,Cornejo-García JA

更新日期：2019-06-01 00:00:00

abstract：:Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma. PubMed, Embase ...

journal_title：Allergy

authors： Agache I,Beltran J,Akdis C,Akdis M,Canelo-Aybar C,Canonica GW,Casale T,Chivato T,Corren J,Del Giacco S,Eiwegger T,Firinu D,Gern JE,Hamelmann E,Hanania N,Mäkelä M,Hernández-Martín I,Nair P,O'Mahony L,Papadopoulos NG

更新日期：2020-05-01 00:00:00

abstract：:Nonallergic non-infectious perennial rhinitis (NANIPER) is a heterogeneous disorder comprising several pathophysiological entities. The etiology of some of these disorders (e.g. drug-induced rhinitis, nonallergic rhinitis with eosinophilia syndrome [NARES], occupational rhinitis, hormonal rhinitis, emotion-induced rhi...

journal_title：Allergy

authors： Garay R

更新日期：2004-01-01 00:00:00

abstract：:The objective was to present a case of periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), summarize the medical literature on PFAPA, review the differential diagnosis and suggest a diagnostic approach to periodic fevers in children. A PubMed search was conducted for all case reports an...

journal_title：Allergy

authors： Lierl M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Levels of n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs in breast milk are associated with the development of allergic diseases up to school age. However, it is unknown whether this relationship persists when the child becomes older. We therefore studied the association between levels of n-3 PUFAs an...

journal_title：Allergy

authors： van Elten TM,van Rossem L,Wijga AH,Brunekreef B,de Jongste JC,Koppelman GH,Smit HA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Allergic asthma is usually considered to be provoked by aeroallergens. However, we have recently recognized a group of children with food allergies who also develop asthma when exposed to the aerosolized form of the food. METHODS:Between 1997 and 1999 we prospectively identified children with an immunoglobu...

journal_title：Allergy

authors： Roberts G,Golder N,Lack G

更新日期：2002-08-01 00:00:00

abstract：:Hyposmia is a common symptom in allergic rhinitis. However, little is known about differences in the olfactory function of patients with seasonal or perennial allergy. A prospective controlled study was performed on 28 patients with allergic rhinitis to grass pollen and on 47 patients with allergic rhinitis to mites. ...

journal_title：Allergy

authors： Moll B,Klimek L,Eggers G,Mann W

更新日期：1998-03-01 00:00:00

abstract：:Application of strict diagnostic criteria to celiac disease has led to the realization that there is a wide clinical spectrum within this disease. Normally there are immune reactions to dietary proteins, particularly secretory antibodies of IgA class, low titers of serum antibody and specific down-regulation of IgE an...

journal_title：Allergy

authors： Ferguson A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS:Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk ...

journal_title：Allergy

authors： Staden U,Rolinck-Werninghaus C,Brewe F,Wahn U,Niggemann B,Beyer K

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Skin biopsies promote our understanding of atopic dermatitis/AD pathomechanisms in infants/toddlers with early-onset AD, but are not feasible in pediatric populations. Tape strips are an emerging, minimally invasive alternative, but global transcriptomic profiling in early pediatric AD is lacking. We aimed t...

journal_title：Allergy

authors： Pavel AB,Renert-Yuval Y,Wu J,Del Duca E,Diaz A,Lefferdink R,Fang MM,Canter T,Rangel SM,Zhang N,Krueger JG,Paller AS,Guttman-Yassky E

更新日期：2021-01-01 00:00:00

abstract：:Ispaghula powder, which is used as a component in bulk laxatives, is known to induce allergic reactions when inhaled by occupationally exposed persons. We have tested whether nurses sensitized by inhalation could get allergic symptoms when challenged by eating ispaghula. Of six nurses tested, all developed symptoms fr...

journal_title：Allergy

authors： Machado L,Stålenheim G

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:IL-31 is a cytokine expressed by T cells following activation with cytokines or staphylococcal exotoxins. A major function of IL-31 in atopic dermatitis (AD) is the induction of pruritus in the skin via the IL-31 receptor on sensory nerve cells. However, the regulation of the IL-31 receptor and pro-inflammat...

journal_title：Allergy

authors： Kasraie S,Niebuhr M,Werfel T

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:A previous investigation of all 10 TLR genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. This study therefore searches for rare variants in the TLR8 region and ...

journal_title：Allergy

authors： Henmyr V,Lind-Halldén C,Carlberg D,Halldén C,Melén E,Wickman M,Bergström A,Säll T,Cardell LO

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Recent studies have yielded heterogeneous results regarding the relationship between vitamin D and atopic conditions. The aim of this study was to investigate the association between serum vitamin D level and the prevalence of eczema in German children and adolescents. METHODS:Data were drawn for children a...

journal_title：Allergy

authors： Heimbeck I,Wjst M,Apfelbacher CJ

更新日期：2013-07-01 00:00:00

abstract：:Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

journal_title：Allergy

authors： Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Food atopy patch tests (APTs) are considered a useful tool for the diagnosis of food allergy. Hypersensitivity to peanuts has not been investigated by means of APTs so far. METHODS:APTs and skin prick tests (SPTs) with peanuts were performed in 136 atopic dermatitis (AD) patients. Relevance of positive and ...

journal_title：Allergy

authors： Seidenari S,Giusti F,Bertoni L,Mantovani L

更新日期：2003-06-01 00:00:00

abstract：:MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidemiological, clinical and basic research using a stepwise, large-scale ...

journal_title：Allergy

authors： Bousquet J,Anto JM,Akdis M,Auffray C,Keil T,Momas I,Postma DS,Valenta R,Wickman M,Cambon-Thomsen A,Haahtela T,Lambrecht BN,Lodrup Carlsen KC,Koppelman GH,Sunyer J,Zuberbier T,Annesi-Maesano I,Arno A,Bindslev-Jensen C

更新日期：2016-11-01 00:00:00

abstract：:The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

journal_title：Allergy

authors： Wüthrich B

更新日期：1998-01-01 00:00:00

abstract：:Standardized bronchial allergen provocation with the same individual allergen dose was performed 3-9 times in 20 symptomless adult asthmatic patients at intervals of 1 week or more during 1/2-22 months in order to study variations in bronchial response. The immediate type reaction was recorded by monitoring FEV1, FVC,...

journal_title：Allergy

authors： Loẅhagen O,Lindholm NB

更新日期：1980-06-01 00:00:00

abstract：:Specific Immunotherapy for respiratory allergy is used since about one century and there is now solid documentation of its efficacy. Nevertheless, the methods and experimental designs used in clinical trials are quite heterogeneous and there is no unanimously accepted methodological standard. Many studies are planned ...

journal_title：Allergy

authors： Canonica GW,Baena-Cagnani CE,Bousquet J,Bousquet PJ,Lockey RF,Malling HJ,Passalacqua G,Potter P,Valovirta E

更新日期：2007-03-01 00:00:00

abstract：:The diagnosis of food IgE-dependent hypersensitivity is based on the demonstration of specific IgE, completed by provocation tests. Two immunoenzymatic techniques, the Phadezym and the FAST, are compared with the Phadebas RAST, in 86 sera (23 controls, 28 from patients with a reported food allergy and 35 with a positi...

journal_title：Allergy

authors： Moneret-Vautrin DA,Gueant JL,Abdel-Ghani A,Maria Y,Nicolas JP

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:While immediate-type clinical reactions to food can quite easily be identified by history or measurement of specific IgE in combination with positive oral food challenges, the evaluation of food allergy in the absence of immediate clinical reactions still presents diagnostic difficulties--particularly in chi...

journal_title：Allergy

authors： Niggemann B,Reibel S,Wahn U

更新日期：2000-03-01 00:00:00

abstract：:Climate therapy has been used for decades in the treatment of atopic dermatitis (AD), but evidence of its effectiveness has not yet been assessed systematically. A systematic literature search in Medline, Embase, and the Cochrane library was performed to identify all original studies concerning alpine climate treatmen...

journal_title：Allergy

authors： Fieten KB,Weststrate AC,van Zuuren EJ,Bruijnzeel-Koomen CA,Pasmans SG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-9, an enzyme that contributes to inflammatory responses and subsequent tissue remodelling, has recently been suggested to be a good biomarker for monitoring disease activity in patients with chronic urticaria (CU). Here, we assessed whether total MMP-9 and/or active MMP-9 plasm...

journal_title：Allergy

authors： Altrichter S,Boodstein N,Maurer M

更新日期：2009-04-01 00:00:00

abstract：:The efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double-blind, placebo-controlled trials (N = 1871) comparing the efficacy and safety of the SQ-standardized grass allergy immunotherapy...

journal_title：Allergy

authors： Nelson H,Blaiss M,Nolte H,Würtz SØ,Andersen JS,Durham SR

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Measurement of exposure to the dust mite allergen Der p 1 is important in asthma research and is potentially useful in managing asthma. As no single measure can capture all characteristics of an exposure, it is important to recognize differences in the available methods of measuring exposure to Der p 1. MET...

journal_title：Allergy

authors： Tovey ER,Mitakakis TZ,Sercombe JK,Vanlaar CH,Marks GB

更新日期：2003-08-01 00:00:00

abstract：:Busereline acetate is an LH-RH agonist that was found to induce local reactions at the injection site or generalized minor skin reactions in some patients. Since these reactions may represent the first reaction of systemic anaphylaxis, we tested the non-specific histamine releasing activity of this drug by intradermal...

journal_title：Allergy

authors： Bousquet J,Hédon B,Hejjaoui A,Chanal I,Michel FB

更新日期：1988-10-01 00:00:00