Respiratory symptoms in ispaghula-allergic nurses after oral challenge with ispaghula suspension.

abstract：:We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation b...

journal_title：Allergy

authors： Apostolovic D,Sánchez-Vidaurre S,Waden K,Curin M,Grundström J,Gafvelin G,Cirkovic Velickovic T,Grönlund H,Thomas WR,Valenta R,Hamsten C,van Hage M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Endothelial (EMPs) and platelet microparticles (PMPs) have been studied as biomarkers in several inflammatory diseases and as central players in intercellular communication. METHODS:In this cross-sectional study, we aimed to assess microparticle levels in asthma. Circulating microparticles and inflammatory ...

journal_title：Allergy

authors： Duarte D,Taveira-Gomes T,Sokhatska O,Palmares C,Costa R,Negrão R,Guimarães JT,Delgado L,Soares R,Moreira A

更新日期：2013-08-01 00:00:00

abstract：:The prevalence of chronic immune and metabolic disorders is increasing rapidly. In particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive pulmonary disease have become major healthcare and economic burdens worldwide. Recent advances in microbiome research have led to significant dis...

journal_title：Allergy

authors： Alemao CA,Budden KF,Gomez HM,Rehman SF,Marshall JE,Shukla SD,Donovan C,Forster SC,Yang IA,Keely S,Mann ER,El Omar EM,Belz GT,Hansbro PM

更新日期：2020-08-06 00:00:00

abstract：:During the last few years, an impressive amount of experimental studies and clinical trials have dealt with a variety of distinct topics in allergic skin diseases - especially atopic dermatitis. In this update, we discuss selected recent data that provide relevant insights into clinical and pathophysiological aspects ...

journal_title：Allergy

authors： Wollenberg A,Feichtner K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmin, initiating and propagating danger signals resulting from tissue injury or inflammatory stimuli. The contribution of this immune sensing pathway to the development of allergic and inflammatory responses is unkn...

journal_title：Allergy

authors： Rubić-Schneider T,Carballido-Perrig N,Regairaz C,Raad L,Jost S,Rauld C,Christen B,Wieczorek G,Kreutzer R,Dawson J,Lametschwandner G,Littlewood-Evans A,Carballido JM

更新日期：2017-03-01 00:00:00

abstract：:The purpose of this study was to investigate whether uncontrolled asthma was associated with healthcare outcomes among Latin American patients with asthma. We used data from 2168 patients with asthma who participated in the 2011 Latin America Asthma Insights and Management (AIM) survey. Using Global Initiative for Ast...

journal_title：Allergy

authors： Gold LS,Montealegre F,Allen-Ramey FC,Jardim J,Smith N,Sansores R,Sullivan SD

更新日期：2013-11-01 00:00:00

abstract：:The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line of defense. Apart from the well-described physical barrier and the mucociliary clearance, a variety of systems, including the airway microbiome, antimicrobial pr...

journal_title：Allergy

authors： Zhang N,Van Crombruggen K,Gevaert E,Bachert C

更新日期：2016-03-01 00:00:00

abstract：:A simple microtiter assay for eosinophil activation is described. The assay used 1000-4000 eosinophils/microtiter well, and the design allows for a separate or simultaneous quantitative assessment of eosinophil adhesion to protein-coated microtiter wells and degranulation after stimulation with eosinophil-activating f...

journal_title：Allergy

authors： Reimert CM,Skov PS,Poulsen LK

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Nasal congestion is the predominant symptom in perennial allergic rhinitis (PAR), and it seems to be mainly related to the late-phase inflammatory events. The present pilot study aimed to evaluate the therapeutic effect exerted by fexofenadine in patients with PAR due to mite allergy. METHODS:This study was...

journal_title：Allergy

authors： Ciprandi G,Cosentino C,Milanese M,Mondino C,Canonica GW

更新日期：2001-11-01 00:00:00

abstract：:It was the aim of this investigation to study the efficacy of a corticosteroid given as a depot injection in seasonal allergic rhinitis, the efficacy profile with regard to specific symptoms, and whether the injection is best given early in the season or later at the peak of the pollen count. An injection of 80 mg met...

journal_title：Allergy

authors： Borum P,Grønborg H,Mygind N

更新日期：1987-01-01 00:00:00

abstract：:The bronchial epithelium acts as a physical barrier to the ingress of airborne irritants and plays an active role in the airways immune response, reacting to a range of environmental stimuli to enable interaction with immune and inflammatory cells. It is well established that mucosal damage and epithelial cell sheddin...

journal_title：Allergy

authors： Davies DE,Polosa R,Puddicombe SM,Richter A,Holgate ST

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Various techniques have been tried in an attempt to reduce allergen levels in homes. This study investigated the effect of dry heat on mite, cat, and dog allergens. METHODS:Samples (50 mg) of Dermatophagoides pteronyssinus and D. farinae cultures, and of house dust rich in the major cat and dog allergens Fe...

journal_title：Allergy

authors： Cain G,Elderfield AJ,Green R,Smillie FI,Chapman MD,Custovic A,Woodcock A

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Physicians typically rely heavily on self-reported symptoms to make a diagnosis of exercise-induced bronchoconstriction (EIB). However, in elite sport, respiratory symptoms have poor diagnostic value. In 2009, following a change in international sports regulations, all elite athletes suspected of asthma and/...

journal_title：Allergy

authors： Ansley L,Kippelen P,Dickinson J,Hull JH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Environmental factors, including the intrauterine environment, can influence the risk of allergy development. In the present study, we investigated whether lifestyle and parental allergen sensitization status are reflected at gene expression level in the intrauterine environment. METHODS:  mRNA expression o...

journal_title：Allergy

authors： Joerink M,Oortveld MA,Stenius F,Rindsjö E,Alm J,Scheynius A

更新日期：2010-10-01 00:00:00

abstract：:Although studies of families, inbred populations and twins have established that asthma has a hereditary basis, little evidence has shown that intrinsic asthma has an increased familial occurrence. To document this issue, we compared the prevalence of asthma in families of intrinsic asthmatics, extrinsic asthmatics an...

journal_title：Allergy

authors： Pirson F,Charpin D,Sansonetti M,Lanteaume A,Kulling G,Charpin J,Vervloet D

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific in...

journal_title：Allergy

authors： Pignatti P,Perfetti L,Galdi E,Pozzi V,Bossi A,Biale C,Moscato G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig) A represents a first-line defence mechanism in the airways, but little is known regarding its implication in upper airway disorders. This study aimed to address the hypothesis that polymeric Ig receptor (pIgR)-mediated secretory IgA immunity could be impaired in chronic upper airway disea...

journal_title：Allergy

authors： Hupin C,Rombaux P,Bowen H,Gould H,Lecocq M,Pilette C

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains unclear. METHODS:FLG mutations R501X, 2282del4 and R2447X were genotyped in the Prevention and Incidence of Asthma and Mite Allergy birth cohort (n = 934) to evalu...

journal_title：Allergy

authors： Schuttelaar ML,Kerkhof M,Jonkman MF,Koppelman GH,Brunekreef B,de Jongste JC,Wijga A,McLean WH,Postma DS

更新日期：2009-12-01 00:00:00

abstract：:There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

journal_title：Allergy

authors： Panush RS,Veloso ML,Weiss S,Bielory L

更新日期：1995-01-01 00:00:00

abstract：:Delayed hypersensitivity to rubber chemicals is well known, but there are only a limited number of case reports on an immediate type of hypersensitivity inducing contact urticaria. We have recently seen several patients with rubber glove-induced contact urticaria who have had both positive skin prick tests and positiv...

journal_title：Allergy

authors： Axelsson JG,Johansson SG,Wrangsjö K

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Artemisia annua is an important autumnal pollen allergen for seasonal allergic rhinitis (SAR) in northern China. To date, no study has investigated allergen immunotherapy with A annua. We aimed to investigate the efficacy and mechanisms underlying A annua-sublingual immunotherapy (SLIT). METHODS:This was a ...

journal_title：Allergy

authors： Lou H,Huang Y,Ouyang Y,Zhang Y,Xi L,Chu X,Wang Y,Wang C,Zhang L

更新日期：2020-08-01 00:00:00

abstract：:A study was undertaken to see whether the principal airborne fungi in the North-East Netherlands were also found to be the most reactive in skin testing. Atmospheric samples were taken weekly with the Andersen sampler, from April 1981, up to and including, June 1983. At the same time skin tests of 833 patients referre...

journal_title：Allergy

authors： Beaumont F,Kauffman HF,de Monchy JG,Sluiter HJ,de Vries K

更新日期：1985-04-01 00:00:00

abstract：:Dose- and pH- dependent carbodiimide-mediated coupling of Penicillin-G to polystyrene microtiter-plates that leaves the beta-lactam ring unchanged is described. A new ELISA method was developed using Penicillin-G coated plates. The binding of 3 different monoclonal antibodies as well as human IgG antibodies of the IgG...

journal_title：Allergy

authors： Klein GF,Stanzl U,Fritsch PO,Varga JM

更新日期：1993-04-01 00:00:00

abstract：:Antigen-presenting cells (APCs) of the human gut are heterogeneous, including both macrophages, a variety of dendritic cells and B cells. They are found both in gut-associated lymphoid tissue and in the mucosal lamina propria, especially beneath the surface epithelium. APCs have diverse phenotypes and therefore probab...

journal_title：Allergy

authors： Brandtzaeg P

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:While immediate-type clinical reactions to food can quite easily be identified by history or measurement of specific IgE in combination with positive oral food challenges, the evaluation of food allergy in the absence of immediate clinical reactions still presents diagnostic difficulties--particularly in chi...

journal_title：Allergy

authors： Niggemann B,Reibel S,Wahn U

更新日期：2000-03-01 00:00:00

abstract：:Two hundred and seventy patients with asthma and/or rhinitis (162 or 60% allergic, 108 or 40% non-allergic) were studied for sinus pathology by means of standard X-rays and tomograms. Sinus pathology was defined as abnormal sinus X-rays, either on standard or tomography. Fifty-four percent of the X-rays were classifie...

journal_title：Allergy

authors： De Cleyn KM,Kersschot EA,De Clerck LS,Ortmanns PM,De Schepper AM,Van Bever HP,Stevens WJ

更新日期：1986-07-01 00:00:00

abstract：:Since the pharmacological treatment of allergic diseases is used in patients with alteration of the immune response due to atopy and possible concomitant infections, we have investigated the possible effects of such drugs as cromolyn, theophylline, ketotifen, oxatomide, astemizole, fenoterol, pirenzepine, and rosapros...

journal_title：Allergy

authors： Canonica GW,Ciprandi G

更新日期：1989-01-01 00:00:00

abstract：:Anaphylaxis is a growing paediatric clinical emergency that is difficult to diagnose because a consensus definition was lacking until recently. Many European countries have no specific guidelines for anaphylaxis. This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical g...

journal_title：Allergy

authors： Muraro A,Roberts G,Clark A,Eigenmann PA,Halken S,Lack G,Moneret-Vautrin A,Niggemann B,Rancé F,EAACI Task Force on Anaphylaxis in Children.

更新日期：2007-08-01 00:00:00

abstract：:Inhaled corticosteroids are recommended as first-line therapy in patients with moderate to severe asthma. The use of these agents in the milder form of asthma is controversial because of their potential adverse effects, especially in growing children. We investigated 49 asthmatic children (38 treated with beclomethaso...

journal_title：Allergy

authors： Martinati LC,Bertoldo F,Gasperi E,Fortunati P,Lo Cascio V,Boner AL

更新日期：1998-07-01 00:00:00

abstract：:Regulatory approaches for allergen immunotherapy (AIT) products and the availability of high-quality AIT products are inherently linked to each other. While allergen products are available in many countries across the globe, their regulation is very heterogeneous. First, we describe the regulatory systems applicable f...

journal_title：Allergy

authors： Bonertz A,Roberts GC,Hoefnagel M,Timon M,Slater JE,Rabin RL,Bridgewater J,Pini C,Pfaar O,Akdis C,Goldstein J,Poulsen LK,van Ree R,Rhyner C,Barber D,Palomares O,Sheikh A,Pawankar R,Hamerlijnk D,Klimek L,Agache I,

更新日期：2018-01-01 00:00:00