The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.

abstract：BACKGROUND:Workplace exposure to trimellitic anhydride (TMA) can elicit TMA-specific IgE (sIgE), which may lead to occupational asthma (OA). An occupational immunosurveillance program (OISP) has been implemented to monitor TMA exposure and immunologic outcomes. The purpose of this study was to determine whether TMA-spe...

journal_title：Allergy

authors： Ghosh D,Clay C,Bernstein JA

更新日期：2018-05-01 00:00:00

abstract：:We present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). Monoclonal antibody-based immunoassays were used to quantify Der p 1, Der f 1, Der 2, Lep d 1, and Fel d 1. T...

journal_title：Allergy

authors： Echechipía S,Ventas P,Audícana M,Urrutia I,Gastaminza G,Polo F,Fernández de Corres L

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappaB (NF-kappaB) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappaB suppression in dendritic cells by adenoviral gene transfer of a novel mutated ...

journal_title：Allergy

authors： Zhou LF,Zhang MS,Hu AH,Zhu Z,Yin KS

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Involvement of paranasal sinuses has been suggested in allergic rhinitis but not clearly demonstrated. AIMS:To investigate the relationship between intermittent allergic rhinitis and computerized tomography (CT). METHODS:Twenty patients with intermittent rhinitis and sensitized to cypress pollens underwent...

journal_title：Allergy

authors： Piette V,Bousquet C,Kvedariene V,Dhivert-Donnadieu H,Crampette L,Senac JP,Bousquet J,Demoly P

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Recurrent angioedema (RecA) is a frequent clinical problem characterized by suddenly occurring cutaneous and/or mucosal swellings. Depending on their location, RecA may be painful, hindering, disfiguring, or even life-threatening. The assessment of disease activity in affected patients is important to guide ...

journal_title：Allergy

authors： Weller K,Groffik A,Magerl M,Tohme N,Martus P,Krause K,Metz M,Staubach P,Maurer M

更新日期：2013-09-01 00:00:00

abstract：:We developed an antigen- and isotype-specific ELISA for the rapid detection of native serum immune complexes (IC). It is a sandwich assay, in which a solid phase antigen-specific capture antibody selectively binds the antigen-specific IC via the antigen. The isotype of the bound IC is then identified using an enzyme-l...

journal_title：Allergy

authors： Bell SJ,Potter PC

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Specific IgE tests are sometimes difficult to interpret due to structural similarities between certain food and pollen allergens. This may be the reason why concomitant sensitization to peanut and birch pollen is frequently seen. The aim of this study was to investigate reported symptoms to peanut- and birch...

journal_title：Allergy

authors： Asarnoj A,Ostblom E,Ahlstedt S,Hedlin G,Lilja G,van Hage M,Wickman M

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Chronic cough, one of the most frequent causes for a patient to consult a medical practitioner, limits the course of normal activities in everyday life of the patient affected (work, physical activities, social relations, night sleep). By now, there are few validated questionnaires for the evaluation of th...

journal_title：Allergy

authors： Baiardini I,Braido F,Fassio O,Tarantini F,Pasquali M,Tarchino F,Berlendis A,Canonica GW

更新日期：2005-04-01 00:00:00

abstract：RATIONALE:The European Position Paper on Sinusitis (EPOS) guidelines provide composite criteria to evaluate chronic rhinosinusitis (CRS) control, taking into consideration the severity of patients' symptoms, aspect of nasal mucosa and medical intake as parameters of CRS control. OBJECTIVES:To study the degree of CRS c...

journal_title：Allergy

authors： van der Veen J,Seys SF,Timmermans M,Levie P,Jorissen M,Fokkens WJ,Hellings PW

更新日期：2017-02-01 00:00:00

abstract：:Eighteen children with perennial asthma and allergy to house-dust mite (HDM) underwent a bronchial challenge with HDM. Before and 24 h after the test, a venous blood sample was taken to determine levels of eosinophils, eosinophil cationic protein (ECP), soluble interleukin-2 receptor (IL-2R), and interleukin-6 (IL-6)....

journal_title：Allergy

authors： Van Bever HP,Moens MM,Bridts CH,De Clerck LS,Mertens AV,Bosmans E,Stevens WJ

更新日期：1993-08-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：:An egg protein, lysozyme, is a still unlabeled additive currently used in cheese preparation. Furthermore, the WHO-FAO committee considers it innocuous. However, 31% of children and 8% of adults with food allergies are allergic to eggs. This work aimed to determine the percentage of patients sensitized to lysozyme fro...

journal_title：Allergy

authors： Frémont S,Kanny G,Nicolas JP,Moneret-Vautrin DA

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The capacity of profilin to induce allergic symptoms in patients with respiratory allergy has been questioned. In this sense, the aim of this study was to investigate the correlation between profilin exposure and induction of symptoms in a prospective case-control study. METHODS:The concentration of profili...

journal_title：Allergy

authors： Ruiz-Hornillos J,López-Matas MA,Berges Jimeno P,Henríquez A,Blanco S,Seoane-Rodríguez M,Mahíllo I,Carnés J

更新日期：2020-04-01 00:00:00

abstract：:Drug-induced erythema multiforme is reported with many antimicrobial and antipyretic medications. We present one patient who experienced erythema multiforme and urticaria after administration of pyrazinamide for treatment of cutaneous tuberculosis. The side-effects of pyrazinamide include hepatic or dermatologic disor...

journal_title：Allergy

authors： Perdu D,Lavaud F,Prévost A,Deschamps F,Cambie MP,Bongrain E,Barhoum K,Kalis B

更新日期：1996-05-01 00:00:00

abstract：:A study was performed in 43 workers exposed to methyltetrahydrophthalic anhydride (MTHPA) used as a hardener in an epoxy resin system. Ten workers sensitized to MTHPA (group SS; presence of serum IgE antibodies against a conjugate of MTHPA and human serum albumin (HSA) detected by RAST) had significantly higher levels...

journal_title：Allergy

authors： Nielsen J,Welinder H,Bensryd I,Andersson P,Skerfving S

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is common in Kuwait, a desert country, but the sensitizing allergens are uncertain. This study investigated the sensitizing allergens in Kuwaiti patients with extrinsic asthma. METHODS:A total of 553 asthmatics (male:female ratio: 1.4; mean age: 31.7 years [range 3-76 years]) and 112 matche...

journal_title：Allergy

authors： Ezeamuzie CI,Thomson MS,Al-Ali S,Dowaisan A,Khan M,Hijazi Z

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Associations between vitamin D status and childhood asthma are increasingly reported, but direct causation and mechanisms underlying an effect remain unknown. We investigated the effect of early-life vitamin D deficiency on the development of murine neonatal allergic airways disease (AAD). METHODS:In utero ...

journal_title：Allergy

authors： Vasiliou JE,Lui S,Walker SA,Chohan V,Xystrakis E,Bush A,Hawrylowicz CM,Saglani S,Lloyd CM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The cytokine network is thought to be essential in orchestrating airway inflammation in asthma. Although evidence has accumulated to suggest that atopic asthma is a Th2 disease, much less is known about nonatopic asthma. METHODS:We have compared the production of IL-4, IL-6, IFN-gamma, and TNF-alpha from pe...

journal_title：Allergy

authors： Bettiol J,Bartsch P,Louis R,De Groote D,Gevaerts Y,Louis E,Malaise M

更新日期：2000-12-01 00:00:00

abstract：:Topical corticosteroids have proved to be effective in the treatment of allergic rhinitis. The symptomatology of allergic rhinitis is considered to be the result of the accumulation and activation of inflammatory cells and cytokine release and hence the efficacy of corticosteroids is associated with their anti-inflamm...

journal_title：Allergy

authors： Fokkens WJ,Godthelp T,Holm AF,Blom H,Klein-Jan A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Quantitative relationships between immunological reactivity, non-specific bronchial responsiveness and bronchial responsiveness to allergens have scarcely been investigated in occupational asthma. METHODS:We assessed the above relationships in 24 subjects with baker's asthma. The skin endpoint titration to ...

journal_title：Allergy

authors： Quirce S,Fernández-Nieto M,Escudero C,Cuesta J,de Las Heras M,Sastre J

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. OBJECTIVES:To investigate the role of RV infections in preschool asthma: (i) susceptibility factors, (ii) clinical cou...

journal_title：Allergy

authors： Jartti T,Liimatainen U,Xepapadaki P,Vahlberg T,Bachert C,Finotto S,Kowalski ML,Sobanska A,Lukkarinen H,Pasioti M,Vuorinen T,Zhang N,Zimmermann T,Papadopoulos NG

更新日期：2021-01-01 00:00:00

abstract：:Thirty children with rhinoconjunctivitis due to birch pollinosis were treated in a double blind manner for 10 months with enteric-coated capsules containing either a birch pollen preparation (n = 14) with doses up to 1.4 X 10(6) biologic units per day or placebo (n = 16). Compared with the placebo group the actively t...

journal_title：Allergy

authors： Möller C,Dreborg S,Lanner A,Björkstén B

更新日期：1986-05-01 00:00:00

abstract：:We studied the effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL-2H3) cells. Among tea polyphenols, (-)- epigallocatechin gallate (EGCG) most strongly and dose-dependently inhibited histamine release from cells stimulated with a calcium ionophore, A23187. (-)-Epigallocatechin (EGC) and (...

journal_title：Allergy

authors： Matsuo N,Yamada K,Shoji K,Mori M,Sugano M

更新日期：1997-01-01 00:00:00

abstract：:The role of cytokines in the accumulation of eosinophil granulocytes in inflamed tissue has been studied extensively during recent years, and these molecules have been found to participate throughout the whole process of eosinophil recruitment. Haematopoietic cytokines such as IL-3, IL-5 and GM-CSF stimulate the proli...

journal_title：Allergy

authors： Lampinen M,Carlson M,Håkansson LD,Venge P

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a chronic airway inflammatory disease involving the complementary actions of innate and adaptive immune responses. Endogenously generated cannabinoids acting via CB2 receptors play important roles in both homeostatic and inflammatory processes. However, the contribution of CB2-acting eicos...

journal_title：Allergy

authors： Ferrini ME,Hong S,Stierle A,Stierle D,Stella N,Roberts K,Jaffar Z

更新日期：2017-06-01 00:00:00

abstract：:Respiratory epithelial mast cells are an expression of airway inflammatory processes. Nasal epithelial mast cells are known to be increased in allergic rhinitis and have now been examined in patients with nasal polyps. Metachromatic cell counts (mean +/- standard error) expressed as the sum of large mast cells, atypic...

journal_title：Allergy

authors： Ruhno J,Howie K,Anderson M,Andersson B,Vanzieleghem M,Hitch D,Lapp P,Denburg J,Dolovich J

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:IgE is the central antibody isotype in TH2-biased immunity and allergic diseases. The structure of intact IgE and the impact of IgE-targeting molecules on IgE however remain elusive. In order to obtain insights into IgE biology and the clinical impact, we aimed for structure determination of IgE and the comp...

journal_title：Allergy

authors： Jensen RK,Jabs F,Miehe M,Mølgaard B,Pfützner W,Möbs C,Spillner E,Andersen GR

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Signal transduction pathways mediated by various receptors expressed on mast cells are thought to be complex, and inhibitory signals that turn off activating signals are not known. METHODS:Upstream signaling cascades mediated by several known receptors in bone marrow-derived mast cells that lead to degranul...

journal_title：Allergy

authors： Chang HW,Kanegasaki S,Jin F,Deng Y,You Z,Chang JH,Kim DY,Timilshina M,Kim JR,Lee YJ,Toyama-Sorimachi N,Tsuchiya T

更新日期：2020-06-01 00:00:00

abstract：:Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bake...

journal_title：Allergy

authors： Revsbech P,Dueholm M

更新日期：1990-04-01 00:00:00