Bronchial responsiveness to bakery-derived allergens is strongly dependent on specific skin sensitivity.

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-9, an enzyme that contributes to inflammatory responses and subsequent tissue remodelling, has recently been suggested to be a good biomarker for monitoring disease activity in patients with chronic urticaria (CU). Here, we assessed whether total MMP-9 and/or active MMP-9 plasm...

journal_title：Allergy

authors： Altrichter S,Boodstein N,Maurer M

更新日期：2009-04-01 00:00:00

abstract：:It is well established that different sites in healthy human skin are colonized by distinct microbial communities due to different physiological conditions. However, few studies have explored microbial heterogeneity between skin sites in diseased skin, such as atopic dermatitis (AD) lesions. To address this issue, we ...

journal_title：Allergy

authors： Ottman N,Barrientos-Somarribas M,Fyhrquist N,Alexander H,Wisgrill L,Olah P,Tsoka S,Greco D,Levi-Schaffer F,Soumelis V,Schröder JM,Kere J,Nestle FO,Barker J,Ranki A,Lauerma A,Homey B,Andersson B,Alenius H

更新日期：2020-10-01 00:00:00

abstract：:Inhaled corticosteroids are recommended as first-line therapy in patients with moderate to severe asthma. The use of these agents in the milder form of asthma is controversial because of their potential adverse effects, especially in growing children. We investigated 49 asthmatic children (38 treated with beclomethaso...

journal_title：Allergy

authors： Martinati LC,Bertoldo F,Gasperi E,Fortunati P,Lo Cascio V,Boner AL

更新日期：1998-07-01 00:00:00

abstract：:Although H1 antihistamine compounds (H1) are highly effective in the treatment of allergic rhinitis (AR), their role in the treatment of asthma is still controversial. Because a strong association between AR and bronchial hyperresponsiveness (BHR) has been reported, this study was designed to assess the effect of a ne...

journal_title：Allergy

authors： Aubier M,Neukirch C,Peiffer C,Melac M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Recent studies have yielded heterogeneous results regarding the relationship between vitamin D and atopic conditions. The aim of this study was to investigate the association between serum vitamin D level and the prevalence of eczema in German children and adolescents. METHODS:Data were drawn for children a...

journal_title：Allergy

authors： Heimbeck I,Wjst M,Apfelbacher CJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Blomia tropicalis is an important mite species in the tropical and sub-tropical regions of the world. Blo t 5 is the major allergen with up to 70% sensitization rates in B. tropicalis allergic populations. METHODS:Mice were immunized intramuscularly with naked plasmid DNA encoding Blo t 5 gene with in vivo ...

journal_title：Allergy

authors： Yi FC,Lee BW,Cheong N,Chua KY

更新日期：2005-01-01 00:00:00

abstract：:Elements are vital in airway mucosal physiology and pathology, but their distribution and levels in the mucosa remain unclear. This study uses the state-of-the-art nuclear microscopy facility to map and quantify multiple elements in the histology sections of nasal mucosa from patients with nasal polyps or inverted pap...

journal_title：Allergy

authors： Ren MQ,Zhou YT,Chen HX,Li TY,Vajandar SK,Osipowicz T,Watt F,Li CW

更新日期：2018-03-01 00:00:00

abstract：:We have evaluated the in vitro leukocyte histamine release tests for the diagnosis of allergy to muscle relaxant drugs in 40 patients (Group A) and a control group of 44 subjects with negative leukocyte histamine release (Group B). Non-IgE dependent histamine release, expressed as a percentage of the total blood hista...

journal_title：Allergy

authors： Mata E,Guéant JL,Moneret-Vautrin DA,Bermejo N,Gérard P,Nicolas JP,Laxenaire MC

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Airway epithelial injury is a crucial component of acute and severe asthma pathogenesis and a promising target for treatment of refractory asthma. However, the underlying mechanism of epithelial injury remains poorly explored. Although high levels of polyamines, mainly spermine, have been found in asthma and...

journal_title：Allergy

authors： Jain V,Raina S,Gheware AP,Singh R,Rehman R,Negi V,Murray Stewart T,Mabalirajan U,Mishra AK,Casero RA Jr,Agrawal A,Ghosh B

更新日期：2018-10-01 00:00:00

abstract：:Quantitative risk assessment (QRA) for food allergens has made considerable progress in recent years, yet acceptability of its outcomes remains stymied because of the limited extent to which it has been possible to incorporate severity as a variable. Reaction severity, particularly following accidental exposure, depen...

journal_title：Allergy

authors： Dubois AEJ,Turner PJ,Hourihane J,Ballmer-Weber B,Beyer K,Chan CH,Gowland MH,O'Hagan S,Regent L,Remington B,Schnadt S,Stroheker T,Crevel RWR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergen exposure time periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end...

journal_title：Allergy

authors： Karatzas K,Katsifarakis N,Riga M,Werchan B,Werchan M,Berger U,Pfaar O,Bergmann KC

更新日期：2018-09-01 00:00:00

abstract：:The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...

journal_title：Allergy

authors： Odelram H,Björkstén B,Chan SC,Hanifin JM,Kjellman NI

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Recent evidence indicates that Staphylococcus aureus, one of the most important human pathogens, secretes vesicles into the extracellular milieu. OBJECTIVE:To evaluate whether inhalation of S. aureus-derived extracellular vesicles (EV) is causally related to the pathogenesis of inflammatory pulmonary diseas...

journal_title：Allergy

authors： Kim MR,Hong SW,Choi EB,Lee WH,Kim YS,Jeon SG,Jang MH,Gho YS,Kim YK

更新日期：2012-10-01 00:00:00

abstract：:The aim of this systematic review was to summarize and assess the quality of asthma intervention health economic studies from 2002 to 2007, compare the study findings with clinical management guidelines, and suggest avenues for future improvement of asthma health economic studies. Forty of the 177 studies met our incl...

journal_title：Allergy

authors： Campbell JD,Spackman DE,Sullivan SD

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Allergic diseases have become a major public health problem in developed countries; yet, no reliable, safe and consistently effective treatment is available. DNA immunization has been shown to prevent and balance established allergic responses, however, the high dose of conventional DNA vaccines necessary fo...

journal_title：Allergy

authors： Scheiblhofer S,Gabler M,Leitner WW,Bauer R,Zoegg T,Ferreira F,Thalhamer J,Weiss R

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to investigate the role of SLPI in patients with allergic rhinitis. From this point of view, we also examined leukocyte elastase, alpha1-antitrypsin, and albumin. SLPI is an inhibitor of serine proteases such as leukocyte elastase, cathepsin G, and mast-cell chymase. Since chymase i...

journal_title：Allergy

authors： Westin U,Lundberg E,Wihl JA,Ohlsson K

更新日期：1999-08-01 00:00:00

abstract：:A double-blind parallel trial of astemizole, pheniramine and placebo was carried out in 51 patients with hay fever. Astemizole is a new potent H1-antihistamine with long duration of action but devoid of central activity. Evaluation criteria were daily symptom- and side effect score cards, daily nasal peak flow measure...

journal_title：Allergy

authors： Malmberg H,Holopainen E,Grahne B,Binder E,Savolainen S,Sundberg S

更新日期：1983-05-01 00:00:00

abstract：:MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidemiological, clinical and basic research using a stepwise, large-scale ...

journal_title：Allergy

authors： Bousquet J,Anto JM,Akdis M,Auffray C,Keil T,Momas I,Postma DS,Valenta R,Wickman M,Cambon-Thomsen A,Haahtela T,Lambrecht BN,Lodrup Carlsen KC,Koppelman GH,Sunyer J,Zuberbier T,Annesi-Maesano I,Arno A,Bindslev-Jensen C

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Systemic allergic reactions are a risk for allergen immunotherapy that utilizes intact allergen preparations. We evaluated the safety, efficacy and immune mechanisms of short-course treatment with adjuvant-free Lolium perenne peptides (LPP) following a 6-week dose-escalation protocol. METHODS:In a prospecti...

journal_title：Allergy

authors： Mösges R,Koch AF,Raskopf E,Singh J,Shah-Hosseini K,Astvatsatourov A,Hauswald B,Yarin Y,Corazza F,Haazen L,Pirotton S,Allekotte S,Zadoyan G,Legon T,Durham SR,Shamji MH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Information about the influence of housing and occupant characteristics on mite allergen concentrations is crucial to determine which methods could be used to decrease exposure of susceptible subjects. OBJECTIVES:To identify housing and occupant characteristics that are associated with mite allergen concent...

journal_title：Allergy

authors： van Strien RT,Gehring U,Belanger K,Triche E,Gent J,Bracken MB,Leaderer BP

更新日期：2004-06-01 00:00:00

abstract：:We describe two uncommon cases of oral allergy syndrome (OAS) after eating pistachio nuts (p.n.) in subjects (a 54-year-old man and a 3-year-old girl) with exclusive skin prick test (SPT) positivity to Parietaria (P.) and pistachio nut (p.n.) allergens. Serologic P.- and p.n.-specific IgE determinations were also carr...

journal_title：Allergy

authors： Liccardi G,Mistrello G,Noschese P,Falagiani P,D'Amato M,D'Amato G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Two-flow cytometry methods for quantification of degranulated basophil after allergen-specific activation were discussed. The methods are discerned by used membrane receptors--FcepsilonRI or IL-3Ralpha Our goal was to evaluate the diagnostic potential of the methods and to correlate them to allergen-specific...

journal_title：Allergy

authors： Michova A,Abugalia M,Ivanova Ts,Nikolov G,Taskov H,Petrunov B

更新日期：2006-09-01 00:00:00

abstract：UNLABELLED:Aspirin-induced asthma (AIA) is a clinical syndrome characterized by acute airway reaction to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS). The most recent etiological hypothesises is that an overexpression of the enzyme LTC(4) synthase occurs in AIA, with the consequent production of sulf...

journal_title：Allergy

authors： Micheletto C,Tognella S,Visconti M,Pomari C,Trevisan F,Dal Negro RW

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinitis may be abnormally sensitive to stimulation of the ion channel transient receptor potential vanilloid-1 (TRPV1). AIM OF THE STUDY:To examine effects of various TRP ion channel activators on sensory symptoms in allergic rhinitis prior to and during seasonal allergen exposure. ...

journal_title：Allergy

authors： Alenmyr L,Högestätt ED,Zygmunt PM,Greiff L

更新日期：2009-05-01 00:00:00

abstract：:A total of 139 workers (71% of the available work force) in four grain elevator stores in Aalborg, Denmark, participated in a cross-sectional study on the prevalence of storage mite allergy among grain elevator workers. All underwent interview, prick test with a standard panel of allergens and the storage mites Acarus...

journal_title：Allergy

authors： Revsbech P,Andersen G

更新日期：1987-08-01 00:00:00

abstract：:The cellular immunity to Yersinia enterocolitica serotype 3 and crude human thyroid extract in 64 patients with thyroid diseases and 25 controls was studied by the leucocyte migration test. In the patient group as a whole and in patients with Graves' disease and nontoxic diffuse goitre a significantly reduced leucocyt...

journal_title：Allergy

authors： Bech K,Clemmensen O,Larsen JH,Thyme S,Bendixen G

更新日期：1978-04-01 00:00:00

abstract：:Respiratory allergies and subclinical sensitization to aeroallergens were investigated in 129 rural and in 222 urban probands. The incidence of respiratory allergies was not significantly higher in the urban residents. Sensitization to aeroallergens was investigated with Phadezym RAST (house dust mite, Cladosporium, o...

journal_title：Allergy

authors： Popp W,Zwick H,Steyrer K,Rauscher H,Wanke T

更新日期：1989-11-01 00:00:00

abstract：RATIONALE:Nasal allergen provocations may be useful in investigating the pathophysiology of allergic rhinitis and effects of treatments. OBJECTIVE:To use grass pollen nasal allergen challenge (NAC) to investigate the effects of allergen immunotherapy in a cross-sectional study. METHODS:We studied nasal and cutaneous ...

journal_title：Allergy

authors： Scadding GW,Eifan AO,Lao-Araya M,Penagos M,Poon SY,Steveling E,Yan R,Switzer A,Phippard D,Togias A,Shamji MH,Durham SR

更新日期：2015-06-01 00:00:00

abstract：:Hypophysectomized (Hypo-X) rats did not develop contact dermatitis in response to dinitrochlorobenzene (DNCB). Syngeneic pituitary grafts placed under the kidney capsule or daily treatment with prolactin restored the DNCB-reactivity of Hypo-X animals. Combined treatment with other pituitary hormones was ineffective. T...

journal_title：Allergy

authors： Nagy E,Berczi I

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Lesions of bullous pemphigoid (BP), an autoimmune subepidermal blistering disease characterized by the presence of tissue-bound and circulating autoantibodies to hemidesmosomal antigens, harbor a mixed inflammatory cellular infiltrate. In various models, neutrophils, eosinophils, mast cells, monocytes as wel...

journal_title：Allergy

authors： de Graauw E,Sitaru C,Horn MP,Borradori L,Yousefi S,Simon D,Simon HU

更新日期：2018-05-01 00:00:00