Astemizole in the treatment of hay fever.

abstract：:Sera from 425 patients were analysed with Phadebas RAST reagents against a panel of 19 allergens and the most commonly positive results were to grass pollen, Dermatophagoides pteronyssinus and cat epithelium. Of the 275 sera RAST-positive to any allergen, 261 were positive by a RAST technique which used a mixture of t...

journal_title：Allergy

authors： Merrett TG,Pantin CF,Dimond AH,Merrett J

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Synthetic bedding has been associated with increased child wheeze and also higher allergen levels in several studies. We aimed to examine whether the association between synthetic bedding and adverse respiratory outcomes was more evident among skin-prick test (SPT) positive children. METHODS:A cross-section...

journal_title：Allergy

authors： Ponsonby AL,Gatenby P,Glasgow N,Mullins R,Hurwitz M,McDonald T

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Quantitative ELISA kits used for the measurement of indoor allergens are time-consuming. Therefore, an immunodot assay (Dustscreen) has been introduced, so that results can be obtained within 4 h. In order to assess the potential applications of the new method, we compared quantitative ELISA methods and Dust...

journal_title：Allergy

authors： Lau S,Schulz G,Sommerfeld C,Wahn U

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Hen's egg (HE) allergy is a common disease in childhood. HE-specific serum IgE has been correlated with the outcome of oral food challenge tests, and diagnostic decision points have been described as helpful but still not sufficient to reduce the requirement for oral food challenges. The aim of the study was...

journal_title：Allergy

authors： Ahrens B,Lopes de Oliveira LC,Schulz G,Borres MP,Niggemann B,Wahn U,Beyer K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Patch testing is the standard clinical procedure to prove contact sensitization. It is a common practice to attach multiple patch tests at the same time. However, synchronous reactions to unrelated allergens may not be completely unassociated. If so, the reaction in a given test field might be influenced by ...

journal_title：Allergy

authors： Brasch J,Geier J,Schnuch A,Uter W,German Contact Dermatitis Research Group (DKG).,Information Network of Departments of Dermatology (IVDK).

更新日期：2006-12-01 00:00:00

abstract：:Although mediators, such as lipids, cytokines, and chemokines, are related to the appearance of an IPR, there has been no reliable indicator to predict conditions for the appearance of an IPR. In this study, we adopted a proteomic approach to investigate the pathogenesis at the level of the plasma proteins and to deve...

journal_title：Allergy

authors： Rhim T,Choi YS,Nam BY,Uh ST,Park JS,Kim YH,Paik YK,Park CS

更新日期：2009-01-01 00:00:00

abstract：:This paper presents the response in subjects with asthma to gaseous air-pollution levels, weather, and medicine intake as identified by principal-component analysis and neural network techniques. Pulmonary function measured by respiratory peak-flow rate in nonallergic asthmatics was associated with ambient, low-level,...

journal_title：Allergy

authors： Moseholm L,Taudorf E,Frøsig A

更新日期：1993-07-01 00:00:00

abstract：:Leukotrienes are a recently discovered group of arachidonic acid-derived lipid mediators. Using radioimmunoassay and high pressure liquid chromatography (HPLC), we have identified the SRS-A sulphidopeptide leukotrienes (LTC4, LTD4 and LTE4) in nasal washings from patients with allergic rhinitis who underwent nasal cha...

journal_title：Allergy

authors： Shaw RJ,Fitzharris P,Cromwell O,Wardlaw AJ,Kay AB

更新日期：1985-01-01 00:00:00

abstract：:The present study revealed that 73% of surveyed apartments in Moscow whose residents included children with the atopic form of bronchial asthma and sensitization to Dermatophagoides pteronyssinus allergens were infested with the pyroglyphid mites D. pteronyssinus and D. farinae. The number of mites in the surveyed apa...

journal_title：Allergy

authors： Zheltikova TM,Ovsyannikova IG,Gervazieva VB,Platts-Mills TA,Chapman MD,Petrova-Nikitina AD,Stepanova GN

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:The beta-lactam allergic work-up is mostly standardized. However, the negative predictive value of drug provocation tests is not yet well established. METHOD:A historical-prospective multicentre cohort study was conducted in four centres (one in France, one in Portugal, two in Italy) to assess the negative ...

journal_title：Allergy

authors： Demoly P,Romano A,Botelho C,Bousquet-Rouanet L,Gaeta F,Silva R,Rumi G,Rodrigues Cernadas J,Bousquet PJ

更新日期：2010-03-01 00:00:00

abstract：:In this study, we investigated the role of calcium and phospholipid-dependent protein kinase (protein kinase C, PKC) in the modulation of histamine release from human basophils. A novel and potent inhibitor of PKC, K-252a, inhibited the release of histamine induced by anti-IgE in a dose-dependent manner with ID50 (the...

journal_title：Allergy

authors： Morita Y,Takaishi T,Honda Z,Miyamoto T

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-9, an enzyme that contributes to inflammatory responses and subsequent tissue remodelling, has recently been suggested to be a good biomarker for monitoring disease activity in patients with chronic urticaria (CU). Here, we assessed whether total MMP-9 and/or active MMP-9 plasm...

journal_title：Allergy

authors： Altrichter S,Boodstein N,Maurer M

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

journal_title：Allergy

authors： Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

更新日期：2020-04-01 00:00:00

abstract：:The cellular immunity to Yersinia enterocolitica serotype 3 and crude human thyroid extract in 64 patients with thyroid diseases and 25 controls was studied by the leucocyte migration test. In the patient group as a whole and in patients with Graves' disease and nontoxic diffuse goitre a significantly reduced leucocyt...

journal_title：Allergy

authors： Bech K,Clemmensen O,Larsen JH,Thyme S,Bendixen G

更新日期：1978-04-01 00:00:00

abstract：:Ketotifen is marketed throughout the world as an antiallergy drug, but whether it affects infiltration of inflammatory cells into airway mucosa is not known. We studied the effects of ketotifen on symptoms, pulmonary function, and airway inflammation in 25 patients with atopic asthma. Patients took ketotifen (1 mg twi...

journal_title：Allergy

authors： Hoshino M,Nakamura Y,Shin Z,Fukushima Y

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:The measurement of peak nasal inspiratory flow (PNIF) provides a simple, cheap, fast and readily available tool for determining the extent of nasal airway patency. However, there are questions regarding its repeatability when used to assess the degree of nasal obstruction in large populations. Therefore, thi...

journal_title：Allergy

authors： Starling-Schwanz R,Peake HL,Salome CM,Toelle BG,Ng KW,Marks GB,Lean ML,Rimmer SJ

更新日期：2005-06-01 00:00:00

abstract：:We present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). Monoclonal antibody-based immunoassays were used to quantify Der p 1, Der f 1, Der 2, Lep d 1, and Fel d 1. T...

journal_title：Allergy

authors： Echechipía S,Ventas P,Audícana M,Urrutia I,Gastaminza G,Polo F,Fernández de Corres L

更新日期：1995-06-01 00:00:00

abstract：:The phenotypes and receptors of the intraepithelial lymphocytes which are a major component of the mucosal immune system are of considerable interest. Intraepithelial lymphocytes, especially those of the intestines, are well documented. The nasal intraepithelial lymphocytes probably play a key role in the immune defen...

journal_title：Allergy

authors： Pawankar R,Okuda M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:IgE-independent (pseudoallergic) reactions to food and food ingredients are common in a subgroup of adult patients with chronic urticaria, who have daily spontaneous occurrence of wheals. However, for children with chronic urticaria (duration longer than 6 weeks, no physical influence), no data on the import...

journal_title：Allergy

authors： Ehlers I,Niggemann B,Binder C,Zuberbier T

更新日期：1998-11-01 00:00:00

abstract：:Environmental exposures in pregnancy and the early postnatal period affect early immune development. Early immune function and future allergy susceptibility appear to result from a combination of maternal phenotype, infant genotype, and environmental exposures in utero that affect early gene expression. Furthermore, e...

journal_title：Allergy

authors： Prescott SL

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Patients with a previous history of hypersensitivity reaction (HSR) to iodinated contrast media (ICM) are at high risk of the development of HSR to ICM. Many studies have tried to evaluate the diagnostic potential of skin tests in this population but have not yet reached a common conclusion. We investigated ...

journal_title：Allergy

authors： Yoon SH,Lee SY,Kang HR,Kim JY,Hahn S,Park CM,Chang YS,Goo JM,Cho SH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Chronic urticaria (CU) is a frequent skin disease characterized by relapsing appearance of pruritic hives. While clinical symptoms are due to the release of histamine by cutaneous mast cells, the underlying pathophysiology is still unknown. However, previous studies indicate that basophils might be of releva...

journal_title：Allergy

authors： Rauber MM,Pickert J,Holiangu L,Möbs C,Pfützner W

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to investigate the role of SLPI in patients with allergic rhinitis. From this point of view, we also examined leukocyte elastase, alpha1-antitrypsin, and albumin. SLPI is an inhibitor of serine proteases such as leukocyte elastase, cathepsin G, and mast-cell chymase. Since chymase i...

journal_title：Allergy

authors： Westin U,Lundberg E,Wihl JA,Ohlsson K

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Chronic idiopathic urticaria (CIU) impairs quality of life (QoL). Currently, no consensus exists regarding how second-generation H(1)-antihistamines (proven to control CIU symptoms) should be taken long-term: as daily treatment or only when symptoms return (PRN). We sought to determine which regimen improves...

journal_title：Allergy

authors： Grob JJ,Auquier P,Dreyfus I,Ortonne JP

更新日期：2009-04-01 00:00:00

abstract：:This study evaluated the risk factors for developing allergic reactions to alternative drugs such as acetaminophen and nimesulide in 367 patients intolerant of nonsteroidal anti-inflammatory drugs (NSAID) compared to 243 healthy controls. All subjects were given test doses (TD) of acetaminophen and nimesulide, and age...

journal_title：Allergy

authors： Pastorello EA,Zara C,Riario-Sforza GG,Pravettoni V,Incorvaia C

更新日期：1998-09-01 00:00:00

abstract：:The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global social and economic impact, and high numbers of deaths. Many risk factors have been identified in the progression of COVID-19 into a severe and critical st...

journal_title：Allergy

authors： Gao YD,Ding M,Dong X,Zhang JJ,Kursat Azkur A,Azkur D,Gan H,Sun YL,Fu W,Li W,Liang HL,Cao YY,Yan Q,Cao C,Gao HY,Brüggen MC,van de Veen W,Sokolowska M,Akdis M,Akdis CA

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Clinically effective allergen-specific immunotherapy correlates with decreased circulating allergen-specific IL-4+ T cells but increased IFN-gamma+ cells at sites of allergen challenge. Whether immunotherapy promotes trafficking of IFN-gamma+ T cells to peripheral tissues is unknown. As aeroallergen is admin...

journal_title：Allergy

authors： Gardner LM,Spyroglou L,O'Hehir RE,Rolland JM

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:New routes of administering immunotherapy in respiratory allergy are being studied as an alternative to conventional injective immunotherapy. We carried out a study to evaluate the clinical efficacy and effects of sublingual immunotherapy in patients with Parietaria judaica-induced respiratory allergy. METH...

journal_title：Allergy

authors： Purello-D'Ambrosio F,Gangemi S,Isola S,La Motta N,Puccinelli P,Parmiani S,Savi E,Ricciardi L

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Specific allergen immunotherapy (SIT) and nasal steroids (NS) are considered effective anti-inflammatory treatments for allergic rhinitis, although their mechanism of action differs. OBJECTIVE:The aim of this study was to examine the effect of treatment with NS and SIT on different populations of inflammato...

journal_title：Allergy

authors： Rak S,Heinrich C,Scheynius A

更新日期：2005-05-01 00:00:00

abstract：:The presence of viable mold propagules in house dust was investigated by 10 different analytic methods, in order to determine to what extent different results are obtained when different analytic methods are used. Moreover, the value of this measurement as an estimator of the potential exposure to fungi in epidemiolog...

journal_title：Allergy

authors： Verhoeff AP,van Reenen-Hoekstra ES,Samson RA,Brunekreef B,van Wijnen JH

更新日期：1994-08-01 00:00:00