Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites.

abstract：BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

journal_title：Allergy

authors： Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:There has been a world-wide increase in the prevalence of atopic diseases. These atopic diseases, including asthma, allergic rhinoconjunctivitis and atopic eczema/dermatitis, are common in childhood and create a challenge of management for physicians and parents. METHODS:MEDLINE was searched for articles re...

journal_title：Allergy

authors： O'Connell EJ

更新日期：2004-08-01 00:00:00

abstract：:The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

journal_title：Allergy

authors： Wüthrich B

更新日期：1998-01-01 00:00:00

abstract：:Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA). Starting with the smallest ASA doses eliciting bronchial obstruction (threshold doses) we doubled the doses on subsequent days and finally achieved good tolerance of 600 mg ASA per day in 27 patien...

journal_title：Allergy

authors： Kowalski ML,Grzelewska-Rzymowska I,Rozniecki J,Szmidt M

更新日期：1984-04-01 00:00:00

abstract：:An egg protein, lysozyme, is a still unlabeled additive currently used in cheese preparation. Furthermore, the WHO-FAO committee considers it innocuous. However, 31% of children and 8% of adults with food allergies are allergic to eggs. This work aimed to determine the percentage of patients sensitized to lysozyme fro...

journal_title：Allergy

authors： Frémont S,Kanny G,Nicolas JP,Moneret-Vautrin DA

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Mannitol-induced bronchoconstriction in subjects with exercise-induced asthma is associated with increased urinary excretion of 9alpha, 11beta-PGF(2), a metabolite of prostaglandin D(2) (PGD(2)) serving as a mast cell marker. It has however been questioned whether or not human mast cells release PGD(2) and l...

journal_title：Allergy

authors： Gulliksson M,Palmberg L,Nilsson G,Ahlstedt S,Kumlin M

更新日期：2006-12-01 00:00:00

abstract：:The diagnosis of allergic reactions in clinical practice is based on both clinical history and the determination of specific immunoglobulin E (IgE), either in the serum or on skin mast cells. However, for various reasons, identification of the causative factors is not possible in all the cases. Moreover, not all aller...

journal_title：Allergy

authors： Demoly P,Lebel B,Arnoux B

更新日期：2003-07-01 00:00:00

abstract：:For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25 degrees C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60 degrees C to kill the mites, and at 0, 6, 14, 21, and ...

journal_title：Allergy

authors： Kort HS,Kniest FM

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:A one-day intensive educational course on allergy and immunology theory and diagnostic procedure significantly increased the competency of allergy and immunology fellows-in-training. ...

journal_title：Allergy

authors： Elizalde A,Perez EE,Sriaroon P,Nguyen D,Lockey RF,Dorsey MJ

更新日期：2012-09-01 00:00:00

abstract：RATIONALE:Nasal allergen provocations may be useful in investigating the pathophysiology of allergic rhinitis and effects of treatments. OBJECTIVE:To use grass pollen nasal allergen challenge (NAC) to investigate the effects of allergen immunotherapy in a cross-sectional study. METHODS:We studied nasal and cutaneous ...

journal_title：Allergy

authors： Scadding GW,Eifan AO,Lao-Araya M,Penagos M,Poon SY,Steveling E,Yan R,Switzer A,Phippard D,Togias A,Shamji MH,Durham SR

更新日期：2015-06-01 00:00:00

abstract：:Because humans breathe through the nose, the nasal mucosa becomes sensitized to inhalant allergens. Allergic rhinitis is, together with allergic conjunctivitis, the best example of a type I hypersensitivity reaction. It is an inflammation of the nasal mucosa induced by specific immune recognition of exogenous allergen...

journal_title：Allergy

authors： Van Cauwenberge PB

更新日期：1997-01-01 00:00:00

abstract：:A two-site immunometric assay based on monoclonal antibodies (mAb) was developed for the measurement of a 20-kDa major allergen of cow. The sensitivity of this assay was (BDA20) 1 ng/ml. It was used to measure airborne allergen concentrations in 10 Finnish cowsheds. The mean concentration of the BDA20 measured at two ...

journal_title：Allergy

authors： Ylönen J,Virtanen T,Rytkönen M,Mäntyjärvi R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Immunoglobulin E (IgE)-mediated allergy belongs to common chronic disorders resulting from an interaction between both genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31.1, a region that is linked to asthma and ...

journal_title：Allergy

authors： Bucková D,Hollá LI,Schüller M,Znojil V,Vácha J

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The general understanding is that a blood sample for analysis of immunoglobulin (Ig) E antibodies to an allergen suspected to cause an anaphylaxis cannot be drawn until several weeks after the reaction. As this is most unpractical, the changes in IgE antibody levels during anaphylaxis were studied to evaluat...

journal_title：Allergy

authors： Guttormsen AB,Johansson SG,Oman H,Wilhelmsen V,Nopp A

更新日期：2007-11-01 00:00:00

abstract：:The aim of the present investigation was to study the dose response relationship of allergen, histamine and histamine releasers in skin prick test (SPT) and the precision of the SPT method. In one experiment timothy allergen, histamine HCl, rabbit anti-human-IgE and compound 48/80 were studied in seven patients. In a ...

journal_title：Allergy

authors： Dreborg S,Holgersson M,Nilsson G,Zetterström O

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Buckwheat flour (BF) is known as a potent food allergen. Sensitization to it usually occurs by ingestion but also by inhalation in occupational or domestic exposure. Buckwheat chaff-stuffed pillows (BCP) can be contaminated with BF during the process of pilling, and many Korean children and adults use BCP fo...

journal_title：Allergy

authors： Lee SY,Lee KS,Hong CH,Lee KY

更新日期：2001-08-01 00:00:00

abstract：:On rare occasions, exposure to methacrylates (MAs) may induce mucosal symptoms. Three patients, two dental laboratory workers and one hearing aid laboratory worker, are presented. All three had allergic contact dermatitis from MAs which disappeared after avoidance of contact with uncured MA compounds. Two of the patie...

journal_title：Allergy

authors： Estlander T,Kanerva L,Kari O,Jolanki R,Mölsä K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Histamine plays an important role in allergic inflammation. Histamine levels are regulated by histamine N-methyltransferase (HNMT). OBJECTIVE:To investigate the functional variability of HNMT gene in relation to genetic polymorphisms in patients with aspirin intolerant chronic urticaria (AICU). METHODS:Two...

journal_title：Allergy

authors： Kim SH,Kang YM,Kim SH,Cho BY,Ye YM,Hur GY,Park HS

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：:Application of strict diagnostic criteria to celiac disease has led to the realization that there is a wide clinical spectrum within this disease. Normally there are immune reactions to dietary proteins, particularly secretory antibodies of IgA class, low titers of serum antibody and specific down-regulation of IgE an...

journal_title：Allergy

authors： Ferguson A

更新日期：1995-01-01 00:00:00

abstract：:The prevalence of chronic immune and metabolic disorders is increasing rapidly. In particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive pulmonary disease have become major healthcare and economic burdens worldwide. Recent advances in microbiome research have led to significant dis...

journal_title：Allergy

authors： Alemao CA,Budden KF,Gomez HM,Rehman SF,Marshall JE,Shukla SD,Donovan C,Forster SC,Yang IA,Keely S,Mann ER,El Omar EM,Belz GT,Hansbro PM

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Improving quality of life is considered to be a major endpoint and motivation for clinical intervention in patients with perennial allergic rhinitis (PAR). In addition to classical symptoms of congestion, pruritus, and rhinorrhea, patients will often complain of not being able to sleep well at night and of f...

journal_title：Allergy

authors： Hughes K,Glass C,Ripchinski M,Gurevich F,Weaver TE,Lehman E,Fisher LH,Craig TJ

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Exposure to environmental endocrine-disrupting chemicals (EDCs) is associated with allergy, chronic inflammation, and immunodeficiency. Phthalates, the common EDCs used in plastic industry, may act as adjuvants to disrupt immune system and enhance allergy. Plasmacytoid DCs (pDCs) are predominant cells secret...

journal_title：Allergy

authors： Kuo CH,Hsieh CC,Kuo HF,Huang MY,Yang SN,Chen LC,Huang SK,Hung CH

更新日期：2013-07-01 00:00:00

abstract：:In recent years, significant attention has been paid to the use of biotechnology to improve the quality and quantity of the food supply due in part to the projected growth in the world population, plus limited options available for increasing the amount of land under cultivation. Alterations in the food supply induced...

journal_title：Allergy

authors： Lehrer SB,Bannon GA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The role of arachidonic acid metabolites in NSAID-induced hypersensitivity has been studied in depth for NSAID-exacerbated respiratory disease (NERD) and NSAID-exacerbated cutaneous disease (NECD). However, no information is available for NSAID-induced urticarial/angioedema (NIUA), despite it being the most ...

journal_title：Allergy

authors： Doña I,Jurado-Escobar R,Perkins JR,Ayuso P,Plaza-Serón MC,Pérez-Sánchez N,Campo P,Bogas-Herrera G,Bartra J,Torres MJ,Sanak M,Cornejo-García JA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In this study, we examined T cell responses and HLA class II alleles in children with moderate-severe asthma. METHODS:Ninety-six children with moderate-severe asthma w...

journal_title：Allergy

authors： Knutsen AP,Vijay HM,Kumar V,Kariuki B,Santiago LA,Graff R,Wofford JD,Shah MR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Various techniques have been tried in an attempt to reduce allergen levels in homes. This study investigated the effect of dry heat on mite, cat, and dog allergens. METHODS:Samples (50 mg) of Dermatophagoides pteronyssinus and D. farinae cultures, and of house dust rich in the major cat and dog allergens Fe...

journal_title：Allergy

authors： Cain G,Elderfield AJ,Green R,Smillie FI,Chapman MD,Custovic A,Woodcock A

更新日期：1998-12-01 00:00:00

abstract：:The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line of defense. Apart from the well-described physical barrier and the mucociliary clearance, a variety of systems, including the airway microbiome, antimicrobial pr...

journal_title：Allergy

authors： Zhang N,Van Crombruggen K,Gevaert E,Bachert C

更新日期：2016-03-01 00:00:00

abstract：:With an indirect immunofluorescence technique 77% of 96 patients with type I allergy and 40% of 20 patients with intrinsic bronchial asthma showed positive reactions for IgG anti-IgG antibodies in serum. They were present partly in an aggregated state not directly detectable before treatment with dithiothreitol. The a...

journal_title：Allergy

authors： Egeskjold EM,Permin H,Nielsen I,Sørensen HJ,Osterballe O,Kallerup HE

更新日期：1981-11-01 00:00:00