Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features.

abstract：:Basophilocytes from patients with rheumatoid arthritis (RA) responded to leukocyte nuclei from normal persons with histamine release; a similar histamine release induced by the nuclear components RNA and DNA has been demonstrated previously. A role of histamine in RA is also supported by the findings of clinical impro...

journal_title：Allergy

authors： Permin H,Skov PS,Norn S,Geisler A,Klysner R,Andersen V,Wiik A,Manthorpe R,Nielsen H,Petersen J

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Sensitization to atopens is an early phenomenon that overlaps with the onset of atopic dermatitis (AD) in infancy. Early epidermal barrier impairment may facilitate the epicutaneous penetration of atopens. OBJECTIVE:To correlate transepidermal water loss (TEWL) and aeroallergen sensitization in infants with...

journal_title：Allergy

authors： Boralevi F,Hubiche T,Léauté-Labrèze C,Saubusse E,Fayon M,Roul S,Maurice-Tison S,Taïeb A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Venom immunotherapy (VIT) is regarded as an established and efficient treatment of Hymenoptera venom allergy. Different frequencies of side-effects have been reported in the literature, depending on the hyposensitization regimen (conventional outpatient programme, rush immunotherapy, ultra rush immunotherapy...

journal_title：Allergy

authors： Wenzel J,Meissner-Kraemer M,Bauer R,Bieber T,Gerdsen R

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：:: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

journal_title：Allergy

authors： Sørensen P

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed. METHODS:In 18 CRS patients without nasal polyps (CRSNP(-)), 35 CRSNP(+) patients and 22 patients with nasal structural abnormalities w...

journal_title：Allergy

authors： Kirsche H,Niederführ A,Deutschle T,Fuchs C,Riechelmann H

更新日期：2010-01-01 00:00:00

abstract：:Pharmacologic intervention in the management of allergic conjunctivitis was evaluated with different topical ocular agents in man. Their effect can be precisely assessed with the conjunctival provocation test (CPT). A potent specific H1-receptor antagonist, 0.05% mequitazine eye-drops, was tested in a double-blind ran...

journal_title：Allergy

authors： Persi L,Dupin O,Arnaud B,Trinquand C,Michel FB,Bousquet J

更新日期：1997-04-01 00:00:00

abstract：:This multicentre, randomized, double-blind, parallel-group study was designed to compare the efficacy and tolerability of fluticasone propionate aqueous nasal spray 200 micrograms once daily (FPANS 200 micrograms od) with FPANS 200 micrograms twice daily (bd) in patients whose seasonal rhinitis symptoms were not compl...

journal_title：Allergy

authors： Pedersen B,Dahl R,Richards DH,Jacques LA,Larsen BB,Pichler W,Nykanen KN

更新日期：1995-10-01 00:00:00

abstract：:Atopic dermatitis (AD) is a complex inflammatory disorder with multiple interactions between genetic, immune and external factors. The sum of external factors that an individual is exposed to throughout their lifetime is termed the exposome. The exposome spans multiple domains from population to molecular levels and, ...

journal_title：Allergy

authors： Stefanovic N,Flohr C,Irvine AD

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Analyses of exhaled volatile organic compounds (VOCs) have shown promising results when distinguishing individuals with asthma. Currently, there are no biomarkers for uncontrolled asthma. Therefore, we aimed to assess, in a real-life clinical setting, the ability of the exhaled VOC analysis, using an electro...

journal_title：Allergy

authors： Farraia M,Cavaleiro Rufo J,Paciência I,Castro Mendes F,Rodolfo A,Rama T,Rocha SM,Delgado L,Brinkman P,Moreira A

更新日期：2020-07-01 00:00:00

abstract：:A study was undertaken to see whether the principal airborne fungi in the North-East Netherlands were also found to be the most reactive in skin testing. Atmospheric samples were taken weekly with the Andersen sampler, from April 1981, up to and including, June 1983. At the same time skin tests of 833 patients referre...

journal_title：Allergy

authors： Beaumont F,Kauffman HF,de Monchy JG,Sluiter HJ,de Vries K

更新日期：1985-04-01 00:00:00

abstract：:Intramuscular adrenaline is the gold standard treatment for anaphylaxis. Intramuscular injection provides more rapid and higher plasma concentrations than subcutaneous routes. Given the increasing epidemic of obesity patients are at increased risk of subcutaneous delivery, we therefore assessed the depth of subcutaneo...

journal_title：Allergy

authors： Johnstone J,Hobbins S,Parekh D,O'Hickey S

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:It is commonly acknowledged that asthma is exacerbated by viral infections. On the other hand, basophil infiltration of lung tissues has been evidenced postmortem in cases of fatal disease, raising the question of a possible link between these two observations. OBJECTIVES:Herein, we addressed the relationsh...

journal_title：Allergy

authors： Ramadan A,Pham Van L,Machavoine F,Dietrich C,Alkan M,Karasuyama H,Schneider E,Dy M,Thieblemont N

更新日期：2013-06-01 00:00:00

abstract：:Specific Immunotherapy for respiratory allergy is used since about one century and there is now solid documentation of its efficacy. Nevertheless, the methods and experimental designs used in clinical trials are quite heterogeneous and there is no unanimously accepted methodological standard. Many studies are planned ...

journal_title：Allergy

authors： Canonica GW,Baena-Cagnani CE,Bousquet J,Bousquet PJ,Lockey RF,Malling HJ,Passalacqua G,Potter P,Valovirta E

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Type-I-allergy to natural rubber latex (NRL) has been shown to be more prevalent among certain groups of patients. Children suffering from chronic renal failure (CRF) could be a suspected risk group because of their intense exposure to latex through catheters, gloves and anesthetic equipment during frequent ...

journal_title：Allergy

authors： Dehlink E,Prandstetter C,Eiwegger T,Putschögl B,Urbanek R,Szépfalusi Z

更新日期：2004-07-01 00:00:00

abstract：:Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rh...

journal_title：Allergy

authors： Bousquet J,Schunemann HJ,Fonseca J,Samolinski B,Bachert C,Canonica GW,Casale T,Cruz AA,Demoly P,Hellings P,Valiulis A,Wickman M,Zuberbier T,Bosnic-Anticevitch S,Bedbrook A,Bergmann KC,Caimmi D,Dahl R,Fokkens WJ,Gris

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Signal transducer and activator of transcription 1 (STAT1), an intracellular signal transducer and activator of transcription centrally involved in many inflammatory pathways, was recently suggested to play an important role in allergy related immune responses. AIM:Thus, we investigated the effect of polymo...

journal_title：Allergy

authors： Pinto LA,Steudemann L,Depner M,Klopp N,Illig T,Weiland SK,von Mutius E,Kabesch M

更新日期：2007-12-01 00:00:00

abstract：:This guideline is the result of a consensus reached during a panel discussion at the 2nd International Consensus Meeting on Urticaria, Urticaria 2004, a joint initiative of the European Academy of Allergology and Clinical Immunology Dermatology Section and the European Union (EU)-funded network of excellence, GA2LEN. ...

journal_title：Allergy

authors： Zuberbier T,Bindslev-Jensen C,Canonica W,Grattan CE,Greaves MW,Henz BM,Kapp A,Kozel MM,Maurer M,Merk HF,Schäfer T,Simon D,Vena GA,Wedi B,EAACI\/GA2LEN\/EDF.

更新日期：2006-03-01 00:00:00

abstract：:On rare occasions, exposure to methacrylates (MAs) may induce mucosal symptoms. Three patients, two dental laboratory workers and one hearing aid laboratory worker, are presented. All three had allergic contact dermatitis from MAs which disappeared after avoidance of contact with uncured MA compounds. Two of the patie...

journal_title：Allergy

authors： Estlander T,Kanerva L,Kari O,Jolanki R,Mölsä K

更新日期：1996-01-01 00:00:00

abstract：:Application of strict diagnostic criteria to celiac disease has led to the realization that there is a wide clinical spectrum within this disease. Normally there are immune reactions to dietary proteins, particularly secretory antibodies of IgA class, low titers of serum antibody and specific down-regulation of IgE an...

journal_title：Allergy

authors： Ferguson A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:Leukotrienes are a recently discovered group of arachidonic acid-derived lipid mediators. Using radioimmunoassay and high pressure liquid chromatography (HPLC), we have identified the SRS-A sulphidopeptide leukotrienes (LTC4, LTD4 and LTE4) in nasal washings from patients with allergic rhinitis who underwent nasal cha...

journal_title：Allergy

authors： Shaw RJ,Fitzharris P,Cromwell O,Wardlaw AJ,Kay AB

更新日期：1985-01-01 00:00:00

abstract：:Busereline acetate is an LH-RH agonist that was found to induce local reactions at the injection site or generalized minor skin reactions in some patients. Since these reactions may represent the first reaction of systemic anaphylaxis, we tested the non-specific histamine releasing activity of this drug by intradermal...

journal_title：Allergy

authors： Bousquet J,Hédon B,Hejjaoui A,Chanal I,Michel FB

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Patients with a previous history of hypersensitivity reaction (HSR) to iodinated contrast media (ICM) are at high risk of the development of HSR to ICM. Many studies have tried to evaluate the diagnostic potential of skin tests in this population but have not yet reached a common conclusion. We investigated ...

journal_title：Allergy

authors： Yoon SH,Lee SY,Kang HR,Kim JY,Hahn S,Park CM,Chang YS,Goo JM,Cho SH

更新日期：2015-06-01 00:00:00

abstract：:Climate therapy has been used for decades in the treatment of atopic dermatitis (AD), but evidence of its effectiveness has not yet been assessed systematically. A systematic literature search in Medline, Embase, and the Cochrane library was performed to identify all original studies concerning alpine climate treatmen...

journal_title：Allergy

authors： Fieten KB,Weststrate AC,van Zuuren EJ,Bruijnzeel-Koomen CA,Pasmans SG

更新日期：2015-01-01 00:00:00

abstract：:The effect of heat on the allergenicity of beef and bovine serum albumin was investigated among 10 toddlers skin prick test (SPT)-positive to raw and cooked beef. The meat-allergy diagnosis was confirmed during double-blind, placebo-controlled food challenge (DBPCFC) with 180 g of beef cooked for 5 min at 100 degrees ...

journal_title：Allergy

authors： Fiocchi A,Restani P,Riva E,Mirri GP,Santini I,Bernardo L,Galli CL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:The prevalence of allergic rhinoconjunctivitis has increased significantly over the past decades with grass pollen being a common trigger. The impact of allergy on patient's quality of life is substantial. AIM:To investigate the sustained effect on quality of life during the grass pollen season 1 year after...

journal_title：Allergy

authors： Frølund L,Durham SR,Calderon M,Emminger W,Andersen JS,Rask P,Dahl R

更新日期：2010-06-01 00:00:00

abstract：:Anaphylaxis is a growing paediatric clinical emergency that is difficult to diagnose because a consensus definition was lacking until recently. Many European countries have no specific guidelines for anaphylaxis. This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical g...

journal_title：Allergy

authors： Muraro A,Roberts G,Clark A,Eigenmann PA,Halken S,Lack G,Moneret-Vautrin A,Niggemann B,Rancé F,EAACI Task Force on Anaphylaxis in Children.

更新日期：2007-08-01 00:00:00

abstract：:This is the first report on inhalative and ingestive allergy to the common edible mushroom Boletus edulis (Be) (English, edible boletus; German, Steinpilz; French, bolet; Italian, porcino or boleto) belonging to the class Basidiomycetes. Four cases observed in our allergy unit are presented, showing different clinical...

journal_title：Allergy

authors： Torricelli R,Johansson SG,Wüthrich B

更新日期：1997-07-01 00:00:00

abstract：:The efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double-blind, placebo-controlled trials (N = 1871) comparing the efficacy and safety of the SQ-standardized grass allergy immunotherapy...

journal_title：Allergy

authors： Nelson H,Blaiss M,Nolte H,Würtz SØ,Andersen JS,Durham SR

更新日期：2013-02-01 00:00:00