Abstract:
:Basophilocytes from patients with rheumatoid arthritis (RA) responded to leukocyte nuclei from normal persons with histamine release; a similar histamine release induced by the nuclear components RNA and DNA has been demonstrated previously. A role of histamine in RA is also supported by the findings of clinical improvement during treatment with H1 and H2 antihistamines in six of 12 patients with RA in active phase, whereas four showed definite deterioration.
journal_name
Allergyjournal_title
Allergyauthors
Permin H,Skov PS,Norn S,Geisler A,Klysner R,Andersen V,Wiik A,Manthorpe R,Nielsen H,Petersen Jdoi
10.1111/j.1398-9995.1981.tb01852.xsubject
Has Abstractpub_date
1981-08-01 00:00:00pages
435-6issue
6eissn
0105-4538issn
1398-9995journal_volume
36pub_type
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