Heat treatment modifies the allergenicity of beef and bovine serum albumin.

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The Coronavirus disease 2019 (COVID-19) has evolved as a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-)2. Allergists and other health care providers (HCPs) in the field of allergies and associated airway diseases are in the front line, taking care of ...

journal_title：Allergy

authors： Pfaar O,Klimek L,Jutel M,Akdis CA,Bousquet J,Breiteneder H,Chinthrajah S,Diamant Z,Eiwegger T,Fokkens WJ,Fritsch HW,Nadeau KC,O'Hehir RE,O'Mahony L,Rief W,Sampath V,Schedlowski M,Torres M,Traidl-Hoffmann C,Wang DY,

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Fluorescence-labeled MHC class II/peptide tetramer complexes are considered as optimal tools to characterize allergen-specific CD4(+) T cells, but this technique is restricted to frequently expressed HLA class II molecules and knowledge of immunodominant epitopes. In contrast, allergen-stimulated proliferati...

journal_title：Allergy

authors： Van Hemelen D,Mahler V,Fischer G,Fae I,Reichl-Leb V,Pickl W,Jutel M,Smolinska S,Ebner C,Bohle B,Jahn-Schmid B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The inflammation of atopic eczema (AE) is orchestrated not only by T cells predominantly but also B cells, eosinophils and dendritic cells. Recently, a role of invariant natural killer T (NKT) cells has been reported in bronchial asthma and allergy. Natural killer T cells express a restricted repertoire of T...

journal_title：Allergy

authors： Simon D,Kozlowski E,Simon H

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Patients with nonallergic asthma frequently show autoreactivity as do subjects with chronic urticaria (CU). Activation of the coagulation cascade and hyper-expression of vascular endothelial growth factor (VEGF) were recently found in CU, and there is sparse evidence that the same may occur in asthma. OBJEC...

journal_title：Allergy

authors： Asero R,Tedeschi A,Cugno M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Histamine intolerance is thought to trigger manifold clinical symptoms after ingesting histamine-rich food due to reduced activity of diamine oxidase (DAO). No study has hitherto systematically assessed daily fluctuations of histamine levels and DAO activities in symptomatic patients. The aim of the study wa...

journal_title：Allergy

authors： Pinzer TC,Tietz E,Waldmann E,Schink M,Neurath MF,Zopf Y

更新日期：2018-04-01 00:00:00

abstract：:Formoterol, a new beta 2-selective long-acting bronchodilator, was compared with terbutaline in terms of ability to inhibit dual phase skin reactions to anti-human IgE in volunteers. Anti-IgE induced an early wheal and flare reaction (WFR) followed by a progressively increasing induration, the late phase reaction (LCR...

journal_title：Allergy

authors： Grönneberg R,Zetterström O

更新日期：1990-07-01 00:00:00

abstract：:A sustained release preparation of terbutaline sulphate has been formulated (Bricanyl depot tablets) in order to extend the duration and accordingly change the dosage regimen to twice a day. This presentation gives a summary of a clinical trial performed in order to study effect and side effects of terbutaline depot t...

journal_title：Allergy

authors： Taudorf E,Bundgaard A,Fagerström PO,Weeke E,Weeke B

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the preventive potential ...

journal_title：Allergy

authors： Kratzer B,Köhler C,Hofer S,Smole U,Trapin D,Iturri J,Pum D,Kienzl P,Elbe-Bürger A,Gattinger P,Mittermann I,Linhart B,Gadermaier G,Jahn-Schmid B,Neunkirchner A,Valenta R,Pickl WF

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:There has been a world-wide increase in the prevalence of atopic diseases. These atopic diseases, including asthma, allergic rhinoconjunctivitis and atopic eczema/dermatitis, are common in childhood and create a challenge of management for physicians and parents. METHODS:MEDLINE was searched for articles re...

journal_title：Allergy

authors： O'Connell EJ

更新日期：2004-08-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a multifactorial disease of the upper airways with a high prevalence (approximately 11%) in the general population. Different immune and inflammatory mechanisms are involved in its pathogenesis. Alterations in the arachidonic acid pathway (leading to an imbalanced production of eicosano...

journal_title：Allergy

authors： Pezato R,Świerczyńska-Krępa M,Niżankowska-Mogilnicka E,Derycke L,Bachert C,Pérez-Novo CA

更新日期：2012-11-01 00:00:00

abstract：:The frequency of aspirin intolerance by history in 2,592 normal individuals was 0.3%. Although the frequency of aspirin intolerance was similar in adults and children, the bronchospastic type predominated in adults, and only the urticarial type was found in normal children. The frequency of recurrent urticaria, regar...

journal_title：Allergy

authors： Settipane RA,Constantine HP,Settipane GA

更新日期：1980-03-01 00:00:00

abstract：:Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bake...

journal_title：Allergy

authors： Revsbech P,Dueholm M

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Immunoglobulin E (IgE)-mediated allergy belongs to common chronic disorders resulting from an interaction between both genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31.1, a region that is linked to asthma and ...

journal_title：Allergy

authors： Bucková D,Hollá LI,Schüller M,Znojil V,Vácha J

更新日期：2003-10-01 00:00:00

abstract：:ELISA is increasingly used to measure antibodies in new circumstances. Recently, it has been applied to the measurement of IgG subclass antibodies against common antigens in early childhood. These studies have raised concerns about the specificity of some of these assays. This paper details the results of experiments ...

journal_title：Allergy

authors： Ruiz RG,Price JF,Kemeny DM

更新日期：1994-10-01 00:00:00

abstract：:Viruses cause asthmatic exacerbations in schoolchildren. We tested the hypothesis that children who wheezed with viral respiratory tract infections secrete higher levels of the type 1 cytokine interferon-gamma (IFN-gamma) in the peripheral circulation than children who had never wheezed. Blood was taken from 13 childr...

journal_title：Allergy

authors： Leech SC,Price JF,Holmes BJ,Kemeny DM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Allergic asthma is associated with airway inflammation and dysfunction of pulmonary surfactant. Because surfactant proteins (SP) account for immunomodulatory functions as well as biophysical functions, we hypothesized that the allergic response in asthma might be accompanied by a dysregulation of SPs. METHO...

journal_title：Allergy

authors： Erpenbeck VJ,Schmidt R,Günther A,Krug N,Hohlfeld JM

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:While total IgE measurements are often used in clinical practice, it is unclear how they should be interpreted for the diagnosis of allergic disorders. We studied whether total IgE may be used to rule out or predict sensitization and whether there are age or gender differences. METHODS:ROC curves were asses...

journal_title：Allergy

authors： Kerkhof M,Dubois AE,Postma DS,Schouten JP,de Monchy JG

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific in...

journal_title：Allergy

authors： Pignatti P,Perfetti L,Galdi E,Pozzi V,Bossi A,Biale C,Moscato G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

journal_title：Allergy

authors： Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. OBJECTIVES:To investigate the role of RV infections in preschool asthma: (i) susceptibility factors, (ii) clinical cou...

journal_title：Allergy

authors： Jartti T,Liimatainen U,Xepapadaki P,Vahlberg T,Bachert C,Finotto S,Kowalski ML,Sobanska A,Lukkarinen H,Pasioti M,Vuorinen T,Zhang N,Zimmermann T,Papadopoulos NG

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Class I chitinase in natural rubber latex (NRL) has been assumed to be an important allergen, especially concerning its cross-reactivity with fruits like avocado and banana. OBJECTIVES:The present study aimed to produce a recombinant latex class I chitinase from Hevea brasiliensis leaves and to study its im...

journal_title：Allergy

authors： Rihs HP,Dumont B,Rozynek P,Lundberg M,Cremer R,Brüning T,Raulf-Heimsoth M

更新日期：2003-03-01 00:00:00

abstract：:Basophils are evolutionarily conserved in many animal species, in spite of the fact that they account for <1% of peripheral blood leukocyte. This suggests that basophils have an indispensable and nonredundant role in vivo, even though they show some phenotypic similarity with tissue-resident mast cells. However, their...

journal_title：Allergy

authors： Karasuyama H,Obata K,Wada T,Tsujimura Y,Mukai K

更新日期：2011-09-01 00:00:00

abstract：:We describe two uncommon cases of oral allergy syndrome (OAS) after eating pistachio nuts (p.n.) in subjects (a 54-year-old man and a 3-year-old girl) with exclusive skin prick test (SPT) positivity to Parietaria (P.) and pistachio nut (p.n.) allergens. Serologic P.- and p.n.-specific IgE determinations were also carr...

journal_title：Allergy

authors： Liccardi G,Mistrello G,Noschese P,Falagiani P,D'Amato M,D'Amato G

更新日期：1996-12-01 00:00:00

abstract：:Innate immunity is a pivotal defence system of higher organisms. Based on a limited number of receptors, it is capable of recognizing pathogens and to initiate immune responses. Major components of these innate immunity pathogen recognition receptors are the toll-like receptors (TLRs), a family of 11 in humans. They a...

journal_title：Allergy

authors： Tesse R,Pandey RC,Kabesch M

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Signal transduction pathways mediated by various receptors expressed on mast cells are thought to be complex, and inhibitory signals that turn off activating signals are not known. METHODS:Upstream signaling cascades mediated by several known receptors in bone marrow-derived mast cells that lead to degranul...

journal_title：Allergy

authors： Chang HW,Kanegasaki S,Jin F,Deng Y,You Z,Chang JH,Kim DY,Timilshina M,Kim JR,Lee YJ,Toyama-Sorimachi N,Tsuchiya T

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The measurement of peak nasal inspiratory flow (PNIF) provides a simple, cheap, fast and readily available tool for determining the extent of nasal airway patency. However, there are questions regarding its repeatability when used to assess the degree of nasal obstruction in large populations. Therefore, thi...

journal_title：Allergy

authors： Starling-Schwanz R,Peake HL,Salome CM,Toelle BG,Ng KW,Marks GB,Lean ML,Rimmer SJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Chitotriosidase (chitinase 1, Chit1), a major true chitinase in humans, is induced in childhood asthma and has been implicated in the pathogenesis of a variety of inflammatory and tissue remodeling responses. However, the role and the mechanisms that underlie these contributions to the diseases have not been...

journal_title：Allergy

authors： Hong JY,Kim M,Sol IS,Kim KW,Lee CM,Elias JA,Sohn MH,Lee CG

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In this study, we examined T cell responses and HLA class II alleles in children with moderate-severe asthma. METHODS:Ninety-six children with moderate-severe asthma w...

journal_title：Allergy

authors： Knutsen AP,Vijay HM,Kumar V,Kariuki B,Santiago LA,Graff R,Wofford JD,Shah MR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:A previous investigation of all 10 TLR genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. This study therefore searches for rare variants in the TLR8 region and ...

journal_title：Allergy

authors： Henmyr V,Lind-Halldén C,Carlberg D,Halldén C,Melén E,Wickman M,Bergström A,Säll T,Cardell LO

更新日期：2016-03-01 00:00:00