Molecular cloning, purification, and IgE-binding of a recombinant class I chitinase from Hevea brasiliensis leaves (rHev b 11.0102).

abstract：:Delayed-type, T cell-mediated, drug hypersensitivity reactions are a serious unwanted manifestation of drug exposure that develops in a small percentage of the human population. Drugs and drug metabolites are known to interact directly and indirectly (through irreversible protein binding and processing to the derived ...

journal_title：Allergy

authors： Naisbitt DJ,Olsson-Brown A,Gibson A,Meng X,Ogese MO,Tailor A,Thomson P

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Blomia tropicalis is an important mite species in the tropical and sub-tropical regions of the world. Blo t 5 is the major allergen with up to 70% sensitization rates in B. tropicalis allergic populations. METHODS:Mice were immunized intramuscularly with naked plasmid DNA encoding Blo t 5 gene with in vivo ...

journal_title：Allergy

authors： Yi FC,Lee BW,Cheong N,Chua KY

更新日期：2005-01-01 00:00:00

abstract：:The protective effect of terfenadine on inflammatory processes following the early phase of conjunctival provocation tests by specific allergen was assessed in 24 patients suffering from seasonal allergic rhinoconjunctivitis, in a single-blind, randomized, placebo-controlled, parallel-group study. Patients were random...

journal_title：Allergy

authors： Ciprandi G,Buscaglia S,Iudice A,Canonica GW

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Quantitative ELISA kits used for the measurement of indoor allergens are time-consuming. Therefore, an immunodot assay (Dustscreen) has been introduced, so that results can be obtained within 4 h. In order to assess the potential applications of the new method, we compared quantitative ELISA methods and Dust...

journal_title：Allergy

authors： Lau S,Schulz G,Sommerfeld C,Wahn U

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Modulation of leukocyte recruitment through blocking of chemokine receptors has been proposed as an attractive therapeutic strategy. We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensit...

journal_title：Allergy

authors： Gupta S,Erdmann G,Schulz-Maronde S,Escher SE,Richter R,Forssmann WG,Elsner J,Forssmann U

更新日期：2008-10-01 00:00:00

abstract：:The objective was to present a case of periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), summarize the medical literature on PFAPA, review the differential diagnosis and suggest a diagnostic approach to periodic fevers in children. A PubMed search was conducted for all case reports an...

journal_title：Allergy

authors： Lierl M

更新日期：2007-12-01 00:00:00

abstract：:PVG rats given injections of 1 microgram ovalbumin (OA) together with 10 mg Silica gel failed to provide serosal mast cells or lung tissue with the capacity to release histamine on in vitro challenge with the antigen. However, if such animals were injected i.p. with 100 mg of alum (without any further antigen addition...

journal_title：Allergy

authors： Bergstrand H,Andersson I,Nyström I,Pauwels R,Bazin H

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Synthetic bedding has been associated with increased child wheeze and also higher allergen levels in several studies. We aimed to examine whether the association between synthetic bedding and adverse respiratory outcomes was more evident among skin-prick test (SPT) positive children. METHODS:A cross-section...

journal_title：Allergy

authors： Ponsonby AL,Gatenby P,Glasgow N,Mullins R,Hurwitz M,McDonald T

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Specific allergen immunotherapy (SIT) and nasal steroids (NS) are considered effective anti-inflammatory treatments for allergic rhinitis, although their mechanism of action differs. OBJECTIVE:The aim of this study was to examine the effect of treatment with NS and SIT on different populations of inflammato...

journal_title：Allergy

authors： Rak S,Heinrich C,Scheynius A

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The identification of 'unknown' allergic sensitizations may determine the prognosis and treatment of patients with respiratory airway disease. Currently, the presence in homes of 'exotic' animals as pets is increasing. In this article the Siberian hamster or dwarf hamster (Phodopus sungorus) was identified a...

journal_title：Allergy

authors： Bertó JM,Peláez A,Fernández E,Lombardero M,Ferrer M

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs) with stable FOXP3 expression are characterized by a specific demethylated region in the FOXP3 gene (Treg-specific demethylated region, TSDR). The aim of this study was to analyse the influence of prenatal factors on cord blood Treg numbers, as detected by changes in the TSDR demeth...

journal_title：Allergy

authors： Hinz D,Bauer M,Röder S,Olek S,Huehn J,Sack U,Borte M,Simon JC,Lehmann I,Herberth G,LINA study group.

更新日期：2012-03-01 00:00:00

abstract：:In this study, we investigated the role of calcium and phospholipid-dependent protein kinase (protein kinase C, PKC) in the modulation of histamine release from human basophils. A novel and potent inhibitor of PKC, K-252a, inhibited the release of histamine induced by anti-IgE in a dose-dependent manner with ID50 (the...

journal_title：Allergy

authors： Morita Y,Takaishi T,Honda Z,Miyamoto T

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Despite considerable efforts to develop anti dust mite strategies, surprisingly few studies have evaluated the allergen content in different types of mattresses in everyday use. This study investigated the presence of mite feces (an indicator of mite allergens) in foam and spring mattresses. METHODS:The hom...

journal_title：Allergy

authors： Schei MA,Hessen JO,Lund E

更新日期：2002-06-01 00:00:00

abstract：:Ketotifen is marketed throughout the world as an antiallergy drug, but whether it affects infiltration of inflammatory cells into airway mucosa is not known. We studied the effects of ketotifen on symptoms, pulmonary function, and airway inflammation in 25 patients with atopic asthma. Patients took ketotifen (1 mg twi...

journal_title：Allergy

authors： Hoshino M,Nakamura Y,Shin Z,Fukushima Y

更新日期：1997-08-01 00:00:00

abstract：:Hypophysectomized (Hypo-X) rats did not develop contact dermatitis in response to dinitrochlorobenzene (DNCB). Syngeneic pituitary grafts placed under the kidney capsule or daily treatment with prolactin restored the DNCB-reactivity of Hypo-X animals. Combined treatment with other pituitary hormones was ineffective. T...

journal_title：Allergy

authors： Nagy E,Berczi I

更新日期：1981-08-01 00:00:00

abstract：:Slow-reacting substance of anaphylaxis (SRS-A) is an important factor mediating bronchoconstriction in asthma. We developed a guinea pig model for SRS-A mediated bronchoconstriction induced by antigen inhalation. Using this model, we investigated the effect of inhaled WP871, a new anti-allergic drug, on bronchoconstri...

journal_title：Allergy

authors： Kurashima K,Fujimura M,Saito M,Sakamoto S,Miyake Y,Nishi K,Matsuda T

更新日期：1990-05-01 00:00:00

abstract：:: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

journal_title：Allergy

authors： Sørensen P

更新日期：2011-07-01 00:00:00

abstract：:It was the aim of this investigation to study the efficacy of a corticosteroid given as a depot injection in seasonal allergic rhinitis, the efficacy profile with regard to specific symptoms, and whether the injection is best given early in the season or later at the peak of the pollen count. An injection of 80 mg met...

journal_title：Allergy

authors： Borum P,Grønborg H,Mygind N

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Early-life sensitization to indoor allergens predicts asthma development. The aim of this study was to compare allergen concentrations in day-care centers (DCC) with those in private homes. METHODS:Settled airborne dust was collected 4 times a year from 20 German DCC (620 samples) and from the homes of chil...

journal_title：Allergy

authors： Sander I,Lotz A,Neumann HD,Czibor C,Flagge A,Zahradnik E,Raulf M

更新日期：2018-06-01 00:00:00

abstract：:House dust mites (HDMs) are sources of an extensive repertoire of allergens responsible for a range of allergic conditions. Technological advances have accelerated the identification of these allergens and characterized their putative roles within HDMs. Understanding their functional bioactivities is illuminating how ...

journal_title：Allergy

authors： Jacquet A,Robinson C

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The effectiveness of acaricides in homes is controversial. OBJECTIVE:To determine whether disodium octaborate tetrahydrate (DOT) combined with vacuuming lowers dust mite numbers and their allergens in carpets and sofas. METHODS:A 6-month study was carried out with 93 homes, which were randomized into three...

journal_title：Allergy

authors： Codina R,Lockey RF,Diwadkar R,Mobly LL,Godfrey S

更新日期：2003-04-01 00:00:00

abstract：:Basophilocytes from patients with rheumatoid arthritis (RA) responded to leukocyte nuclei from normal persons with histamine release; a similar histamine release induced by the nuclear components RNA and DNA has been demonstrated previously. A role of histamine in RA is also supported by the findings of clinical impro...

journal_title：Allergy

authors： Permin H,Skov PS,Norn S,Geisler A,Klysner R,Andersen V,Wiik A,Manthorpe R,Nielsen H,Petersen J

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed. METHODS:In 18 CRS patients without nasal polyps (CRSNP(-)), 35 CRSNP(+) patients and 22 patients with nasal structural abnormalities w...

journal_title：Allergy

authors： Kirsche H,Niederführ A,Deutschle T,Fuchs C,Riechelmann H

更新日期：2010-01-01 00:00:00

abstract：:The role of cytokines in the accumulation of eosinophil granulocytes in inflamed tissue has been studied extensively during recent years, and these molecules have been found to participate throughout the whole process of eosinophil recruitment. Haematopoietic cytokines such as IL-3, IL-5 and GM-CSF stimulate the proli...

journal_title：Allergy

authors： Lampinen M,Carlson M,Håkansson LD,Venge P

更新日期：2004-08-01 00:00:00

abstract：:Regulatory approaches for allergen immunotherapy (AIT) products and the availability of high-quality AIT products are inherently linked to each other. While allergen products are available in many countries across the globe, their regulation is very heterogeneous. First, we describe the regulatory systems applicable f...

journal_title：Allergy

authors： Bonertz A,Roberts GC,Hoefnagel M,Timon M,Slater JE,Rabin RL,Bridgewater J,Pini C,Pfaar O,Akdis C,Goldstein J,Poulsen LK,van Ree R,Rhyner C,Barber D,Palomares O,Sheikh A,Pawankar R,Hamerlijnk D,Klimek L,Agache I,

更新日期：2018-01-01 00:00:00

abstract：:The phenotypes and receptors of the intraepithelial lymphocytes which are a major component of the mucosal immune system are of considerable interest. Intraepithelial lymphocytes, especially those of the intestines, are well documented. The nasal intraepithelial lymphocytes probably play a key role in the immune defen...

journal_title：Allergy

authors： Pawankar R,Okuda M

更新日期：1993-02-01 00:00:00

abstract：:There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

journal_title：Allergy

authors： Panush RS,Veloso ML,Weiss S,Bielory L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The contribution of B-cell subsets and T-B cell interaction to the pathogenesis of allergic rhinitis (AR) and mechanisms of allergen immunotherapy (AIT) remain poorly understood. This study aimed to outline circulating B-cell signature, the underlying mechanism, and its association with clinical response to ...

journal_title：Allergy

authors： Yao Y,Wang N,Chen CL,Pan L,Wang ZC,Yunis J,Chen ZA,Zhang Y,Hu ST,Xu XY,Zhu RF,Yu D,Liu Z

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Mustard IgE-mediated allergy is supposed to be a rare cause of food allergy, and its clinical features and cross-reactivities have not been fully elucidated. METHODS:A prospective study was carried out, recruiting mustard allergic patients, and paired control subjects. A clinical questionnaire was administe...

journal_title：Allergy

authors： Figueroa J,Blanco C,Dumpiérrez AG,Almeida L,Ortega N,Castillo R,Navarro L,Pérez E,Gallego MD,Carrillo T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is high, there is currently no specific and validated instrument to...

journal_title：Allergy

authors： Siebenhaar F,Sander B,Ho LHT,Ellrich A,Maurer M,Weller K

更新日期：2018-07-01 00:00:00