Development and validation of the mastocytosis activity score.

abstract：BACKGROUND:New therapies are necessary to address inadequate asthma control in many patients. This study sets out to investigate whether hypoxia-inducible factor (HIF) is essential for development of allergic airway inflammation (AAI) and therefore a potential novel target for asthma treatment. METHODS:Mice conditiona...

journal_title：Allergy

authors： Huerta-Yepez S,Baay-Guzman GJ,Bebenek IG,Hernandez-Pando R,Vega MI,Chi L,Riedl M,Diaz-Sanchez D,Kleerup E,Tashkin DP,Gonzalez FJ,Bonavida B,Zeidler M,Hankinson O

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Allergic asthma is usually considered to be provoked by aeroallergens. However, we have recently recognized a group of children with food allergies who also develop asthma when exposed to the aerosolized form of the food. METHODS:Between 1997 and 1999 we prospectively identified children with an immunoglobu...

journal_title：Allergy

authors： Roberts G,Golder N,Lack G

更新日期：2002-08-01 00:00:00

abstract：:Daily sensitization of SPF BNxWi/Fu rats with ovalbumin (OA) in aerosol during 2-week periods with a 4-week interval resulted after 7 weeks in IgE, IgA and IgG antibodies in serum and bronchial fluid. After cultivation of the regional, axillary, brachial and mediastinal (ABM) lymph node cells, IgE antibodies were foun...

journal_title：Allergy

authors： Ahlstedt S,Björkstén B,Hesselmar B,Nygren H,Alving K,Olaisson E

更新日期：1985-05-01 00:00:00

abstract：:Work-related asthma is the most common occupational respiratory disorder in the industrialized countries. It has been postulated that wood dust exposure may increase the risk of work-related asthma. The objective of this study was to assess, through a meta-analysis, the risk of developing work-related asthma associate...

journal_title：Allergy

authors： Pérez-Ríos M,Ruano-Ravina A,Etminan M,Takkouche B

更新日期：2010-04-01 00:00:00

abstract：:Several studies have indicated that the incidence and prevalence of allergic diseases are increasing. Such data should not be regarded as mere statistical curiosities, but should be analysed to provide information on the factors contributing to allergy and its changing epidemiology. Extensive evidence has been accumul...

journal_title：Allergy

authors： Bonini S,Magrini L,Rotiroti G,Ronchetti MP,Onorati P

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:A previous investigation of all 10 TLR genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. This study therefore searches for rare variants in the TLR8 region and ...

journal_title：Allergy

authors： Henmyr V,Lind-Halldén C,Carlberg D,Halldén C,Melén E,Wickman M,Bergström A,Säll T,Cardell LO

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:In a previous controlled study we demonstrated that preseasonal grass pollen immunotherapy for three years was effective in children. In the current study we examined the same group of patients to see if there is still a benefit six years after discontinuation of treatment. METHODS:Thirteen of 14 patients w...

journal_title：Allergy

authors： Eng PA,Reinhold M,Gnehm HP

更新日期：2002-04-01 00:00:00

abstract：:Dose- and pH- dependent carbodiimide-mediated coupling of Penicillin-G to polystyrene microtiter-plates that leaves the beta-lactam ring unchanged is described. A new ELISA method was developed using Penicillin-G coated plates. The binding of 3 different monoclonal antibodies as well as human IgG antibodies of the IgG...

journal_title：Allergy

authors： Klein GF,Stanzl U,Fritsch PO,Varga JM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The reasons for the rise in asthma and allergies remain unclear. To identify risk or protective factors, it is essential to carry out longitudinal epidemiological studies, preferably birth cohort studies. In Europe, several birth cohort studies on asthma and atopic diseases have been initiated over the last ...

journal_title：Allergy

authors： Keil T,Kulig M,Simpson A,Custovic A,Wickman M,Kull I,Lødrup Carlsen KC,Carlsen KH,Smit HA,Wijga AH,Schmid S,Berg A,Bollrath C,Eller E,Bindslev-Jensen C,Halken S,Høst A,Heinrich J,Porta D,Forastiere F,Brunekreef B

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Two-flow cytometry methods for quantification of degranulated basophil after allergen-specific activation were discussed. The methods are discerned by used membrane receptors--FcepsilonRI or IL-3Ralpha Our goal was to evaluate the diagnostic potential of the methods and to correlate them to allergen-specific...

journal_title：Allergy

authors： Michova A,Abugalia M,Ivanova Ts,Nikolov G,Taskov H,Petrunov B

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Mustard IgE-mediated allergy is supposed to be a rare cause of food allergy, and its clinical features and cross-reactivities have not been fully elucidated. METHODS:A prospective study was carried out, recruiting mustard allergic patients, and paired control subjects. A clinical questionnaire was administe...

journal_title：Allergy

authors： Figueroa J,Blanco C,Dumpiérrez AG,Almeida L,Ortega N,Castillo R,Navarro L,Pérez E,Gallego MD,Carrillo T

更新日期：2005-01-01 00:00:00

abstract：:Sera from 425 patients were analysed with Phadebas RAST reagents against a panel of 19 allergens and the most commonly positive results were to grass pollen, Dermatophagoides pteronyssinus and cat epithelium. Of the 275 sera RAST-positive to any allergen, 261 were positive by a RAST technique which used a mixture of t...

journal_title：Allergy

authors： Merrett TG,Pantin CF,Dimond AH,Merrett J

更新日期：1980-09-01 00:00:00

abstract：:A one-day intensive educational course on allergy and immunology theory and diagnostic procedure significantly increased the competency of allergy and immunology fellows-in-training. ...

journal_title：Allergy

authors： Elizalde A,Perez EE,Sriaroon P,Nguyen D,Lockey RF,Dorsey MJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Allergic diseases are more common in Finland than in Estonia, which-according to the biodiversity hypothesis-could relate to differences in early microbial exposures. METHODS:We aimed at defining possible microbial perturbations preceding early atopic sensitization. Stool, nasal and skin samples of 6-month-...

journal_title：Allergy

authors： Ruokolainen L,Parkkola A,Karkman A,Sinkko H,Peet A,Hämäläinen AM,von Hertzen L,Tillmann V,Koski K,Virtanen SM,Niemelä O,Haahtela T,Knip M

更新日期：2020-09-01 00:00:00

abstract：:Antigenic extracts prepared from pollen samples collected at weekly intervals during the same season did not exhibit significant variation in protein concentration. Stored pollen samples from different years, however, showed highly significant variations in protein concentration. The protein content of samples from di...

journal_title：Allergy

authors： Malik P,Singh AB,Gangal SV,Babu CR

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:A cross-sectional retrospective study suggested a link between allergic diseases and Parkinson's disease. However, the temporal association between asthma and Parkinson's disease remains unknown. METHODS:From the Taiwan National Health Insurance Research Database, 10 455 patients who were diagnosed with ast...

journal_title：Allergy

authors： Cheng CM,Wu YH,Tsai SJ,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Tsai CF,Yang AC,Lin WC,Pan TL,Chang WH,Chen TJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Patients with allergic rhinitis may be abnormally sensitive to stimulation of the ion channel transient receptor potential vanilloid-1 (TRPV1). AIM OF THE STUDY:To examine effects of various TRP ion channel activators on sensory symptoms in allergic rhinitis prior to and during seasonal allergen exposure. ...

journal_title：Allergy

authors： Alenmyr L,Högestätt ED,Zygmunt PM,Greiff L

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Sequential human herpes virus (HHV) reactivation is well known in drug reaction with eosinophilia and systemic symptom (DRESS), but such a phenomenon has seldom studied in other types of cutaneous adverse drug reactions (cADRs). Moreover, the association between viral reactivations and cytokine or chemokine ...

journal_title：Allergy

authors： Chen YC,Chiang HH,Cho YT,Chang CY,Chen KL,Yang CW,Lee YH,Chu CY

更新日期：2015-05-01 00:00:00

abstract：:The protective effect of terfenadine on inflammatory processes following the early phase of conjunctival provocation tests by specific allergen was assessed in 24 patients suffering from seasonal allergic rhinoconjunctivitis, in a single-blind, randomized, placebo-controlled, parallel-group study. Patients were random...

journal_title：Allergy

authors： Ciprandi G,Buscaglia S,Iudice A,Canonica GW

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Anaphylaxis is an acute systemic allergic reaction, which can be life-threatening. H(1)-antihistamines are commonly used as an adjuvant therapy in the treatment of anaphylaxis. We sought to assess the benefits and harm of H(1)-antihistamines in the treatment of anaphylaxis. METHODS:We searched the Cochrane ...

journal_title：Allergy

authors： Sheikh A,Ten Broek V,Brown SG,Simons FE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total serum IgE l...

journal_title：Allergy

authors： Tewfik MA,Bossé Y,Lemire M,Hudson TJ,Vallée-Smejda S,Al-Shemari H,Laprise C,Desrosiers M

更新日期：2009-05-01 00:00:00

abstract：:The use of recombinant DNA techniques for the study of allergenicity of proteins is a viable, and in many ways a preferred, alternative to the traditional procedures of protein purification, digestion and analysis of peptides for both allergenicity and amino acid sequence. The process of protein purification can be di...

journal_title：Allergy

authors： Baldo BA,Donovan GR

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:We report on a 37-year-old man without history of previous allergic disease who developed an aseptic intolerance reaction to a chromium-cobalt alloy, with local discomfort, loosening, and absence of fracture healing. Both in vivo and in vitro allergoimmunologic diagnostic tests were performed. METHODS:Patch...

journal_title：Allergy

authors： Thomas P,Summer B,Sander CA,Przybilla B,Thomas M,Naumann T

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Allergic asthma is associated with airway inflammation and dysfunction of pulmonary surfactant. Because surfactant proteins (SP) account for immunomodulatory functions as well as biophysical functions, we hypothesized that the allergic response in asthma might be accompanied by a dysregulation of SPs. METHO...

journal_title：Allergy

authors： Erpenbeck VJ,Schmidt R,Günther A,Krug N,Hohlfeld JM

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Endogenous histamine-releasing factors (HRFs) are involved in 30-60% of patients with chronic urticaria (CU). Evidence for their existence comes from in vivo studies of autoreactivity with the autologous serum skin test (ASST), in vitro immunoassays demonstrating autoantibodies against the immunoglobulin E (...

journal_title：Allergy

authors： Platzer MH,Grattan CE,Poulsen LK,Skov PS

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Early-life sensitization to indoor allergens predicts asthma development. The aim of this study was to compare allergen concentrations in day-care centers (DCC) with those in private homes. METHODS:Settled airborne dust was collected 4 times a year from 20 German DCC (620 samples) and from the homes of chil...

journal_title：Allergy

authors： Sander I,Lotz A,Neumann HD,Czibor C,Flagge A,Zahradnik E,Raulf M

更新日期：2018-06-01 00:00:00

abstract：:Epicutaneous allergen-specific immunotherapy (EPIT) is proposed as an alternative route for allergen-specific immunotherapy (AIT). The induction of allergen-specific blocking IgG antibodies represents an important mechanism underlying AIT, but has not been investigated for EPIT. Here, we compared the induction of alle...

journal_title：Allergy

authors： Cabauatan CR,Campana R,Niespodziana K,Reinisch C,Lundberg U,Meinke A,Henning R,Neubauer A,Valenta R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Specific allergen immunotherapy (SIT) and nasal steroids (NS) are considered effective anti-inflammatory treatments for allergic rhinitis, although their mechanism of action differs. OBJECTIVE:The aim of this study was to examine the effect of treatment with NS and SIT on different populations of inflammato...

journal_title：Allergy

authors： Rak S,Heinrich C,Scheynius A

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Aluminium (ALUM) is used as experimental and clinical adjuvant for parenteral vaccine formulation. It is also contained in anti-acid drugs like sucralfate (SUC). These anti-acids have been shown to cause sensitization to food proteins via elevation of the gastric pH. The aim of this study was to assess the o...

journal_title：Allergy

authors： Brunner R,Wallmann J,Szalai K,Karagiannis P,Altmeppen H,Riemer AB,Jensen-Jarolim E,Pali-Schöll I

更新日期：2009-06-01 00:00:00