Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis.

abstract：:A variety of adverse reactions to local anesthetics has been described, some of which are thought to be allergic. Different protocols of prick and intradermal skin tests as well as subcutaneous challenge tests are used to select a local anesthetic which can safely be used. Their long-term effectiveness has not yet bee...

journal_title：Allergy

authors： Wasserfallen JB,Frei PC

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils ...

journal_title：Allergy

authors： Fettelschoss-Gabriel A,Fettelschoss V,Olomski F,Birkmann K,Thoms F,Bühler M,Kummer M,Zeltins A,Kündig TM,Bachmann MF

更新日期：2019-03-01 00:00:00

abstract：:We present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). Monoclonal antibody-based immunoassays were used to quantify Der p 1, Der f 1, Der 2, Lep d 1, and Fel d 1. T...

journal_title：Allergy

authors： Echechipía S,Ventas P,Audícana M,Urrutia I,Gastaminza G,Polo F,Fernández de Corres L

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:The world's most catastrophic and deadly thunderstorm asthma epidemic struck Melbourne, Australia, on November 21, 2016. OBJECTIVE:Among thunderstorm-affected patients presenting to emergency rooms (ERs), we investigated risk factors predicting severe attacks requiring admission to hospital. METHODS:Thunde...

journal_title：Allergy

authors： Hew M,Lee J,Susanto NH,Prasad S,Bardin PG,Barnes S,Ruane L,Southcott AM,Gillman A,Young A,Rangamuwa K,O'Hehir RE,McDonald C,Sutherland M,Conron M,Matthews S,Harun NS,Lachapelle P,Douglass JA,Irving L,Langton D,M

更新日期：2019-01-01 00:00:00

abstract：:Although copper sulfate can cause systemic contact dermatitis, few such cases have been recorded among copper-releasing IUD users. Reported in this paper is a case of endometritis and urticaria-angioedema syndrome in a 32-year-old user of a copper IUD. Widespread urticaria, as well as angioedema of the eyelids and t...

journal_title：Allergy

authors： Purello D'Ambrosio F,Ricciardi L,Isola S,Gangemi S,Cilia M,Levanti C,Marcazzò A

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Specific IgE tests are sometimes difficult to interpret due to structural similarities between certain food and pollen allergens. This may be the reason why concomitant sensitization to peanut and birch pollen is frequently seen. The aim of this study was to investigate reported symptoms to peanut- and birch...

journal_title：Allergy

authors： Asarnoj A,Ostblom E,Ahlstedt S,Hedlin G,Lilja G,van Hage M,Wickman M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a multifactorial and probably multigenic inflammatory disease of the upper airways, and has been associated with the HLA class II alleles DR4 and DR7. Here we investigated possible associations with other polymorphic susceptibility/resistance genes located within the major histocompatibili...

journal_title：Allergy

authors： Aron Y,Busson M,Polla BS,Dusser D,Lockhart A,Swierczewski E,Favatier F

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The presence of anti-FcepsilonRI and anti-IgE autoantibodies in a subset of patients with chronic urticaria suggests their aetiopathogenetic role. In clinical practice, the presence of these antibodies is usually considered when the autologous serum skin test (ASST) is positive. AIMS:To evaluate if the posi...

journal_title：Allergy

authors： Fusari A,Colangelo C,Bonifazi F,Antonicelli L

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs) with stable FOXP3 expression are characterized by a specific demethylated region in the FOXP3 gene (Treg-specific demethylated region, TSDR). The aim of this study was to analyse the influence of prenatal factors on cord blood Treg numbers, as detected by changes in the TSDR demeth...

journal_title：Allergy

authors： Hinz D,Bauer M,Röder S,Olek S,Huehn J,Sack U,Borte M,Simon JC,Lehmann I,Herberth G,LINA study group.

更新日期：2012-03-01 00:00:00

abstract：:The aim of this study was to investigate possible effects of landscape design on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy from Uzbekistan where green areas have been changed during the last two decades by a State program. Sera from two different generations of Uzbek ...

journal_title：Allergy

authors： Garib V,Wollmann E,Djambekova G,Lemell P,Kmenta M,Berger U,Zieglmayer P,Valenta R

更新日期：2017-10-01 00:00:00

abstract：:The cellular immunity to Yersinia enterocolitica serotype 3 and crude human thyroid extract in 64 patients with thyroid diseases and 25 controls was studied by the leucocyte migration test. In the patient group as a whole and in patients with Graves' disease and nontoxic diffuse goitre a significantly reduced leucocyt...

journal_title：Allergy

authors： Bech K,Clemmensen O,Larsen JH,Thyme S,Bendixen G

更新日期：1978-04-01 00:00:00

abstract：:Cocksfoot/orchard grass (Dactylis glomerata) anther cDNA clones encoding the group II allergen Dac g II were previously isolated on the basis of immunoreactivity of human, rabbit, and murine antibodies with a 24-kDa protein expressed as a fusion protein with beta-galactosidase. Nucleotide sequencing reveals an open re...

journal_title：Allergy

authors： Roberts AM,Bevan LJ,Flora PS,Jepson I,Walker MR

更新日期：1993-11-01 00:00:00

abstract：:An affinity chromatography method for preparation of patient-related antigens from commercially available allergen extracts has been investigated. IgG1,2,4 from a patient previously hyposensitized with dog hair and dandruff allergen was bound to protein A-sepharose. Secondly, commercial allergen extract was applied to...

journal_title：Allergy

authors： Poulsen LK,Søndergaard I,Weeke B

更新日期：1988-11-01 00:00:00

abstract：:Two hundred and seventy patients with asthma and/or rhinitis (162 or 60% allergic, 108 or 40% non-allergic) were studied for sinus pathology by means of standard X-rays and tomograms. Sinus pathology was defined as abnormal sinus X-rays, either on standard or tomography. Fifty-four percent of the X-rays were classifie...

journal_title：Allergy

authors： De Cleyn KM,Kersschot EA,De Clerck LS,Ortmanns PM,De Schepper AM,Van Bever HP,Stevens WJ

更新日期：1986-07-01 00:00:00

abstract：:In analogy with findings from animal experiments, people with low glutathione-peroxidase (GSH-Px) activity could be expected to have altered sensitivities to effects of drugs, chemicals and possibly food. We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance. Ten of...

journal_title：Allergy

authors： Malmgren R,Unge G,Zetterström O,Theorell H,de Wahl K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:There has been no study for evaluating the associations of human leukocyte antigen (HLA) class I and II alleles with toluene diisocyanate (TDI)-induced asthma in an Asian population. OBJECTIVE:The aim of this study was to investigate a susceptible or protective marker of HLA class I and II alleles in TDI-in...

journal_title：Allergy

authors： Kim SH,Oh HB,Lee KW,Shin ES,Kim CW,Hong CS,Nahm DH,Park HS

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:WHO guidelines advocate breastfeeding for 6 months, and EAACI guideline recommends exclusive breastfeeding for 4-6 months. However, evidence for breastfeeding to prevent asthma and allergic disease is conflicting. We examined whether following recommended breastfeeding guidelines alters the long-term risks o...

journal_title：Allergy

authors： Bion V,Lockett GA,Soto-Ramírez N,Zhang H,Venter C,Karmaus W,Holloway JW,Arshad SH

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:In atopic individuals, exposure to allergens is followed by recruitment of blood eosinophils in the target tissue. We investigated whether allergen inhalation challenge could result in depletion of blood eosinophils overexpressing adhesion molecules involved in eosinophil migration. METHODS:Blood eosinophil...

journal_title：Allergy

authors： Lantero S,Spallarossa D,Silvestri M,Sabatini F,Scarso L,Crimi E,Rossi GA

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be defined. Established animal models assessing the role(s) of eosinophils as contributors and/or causative agents of disease have relied on congenitally deficient mice w...

journal_title：Allergy

authors： Jacobsen EA,Lesuer WE,Willetts L,Zellner KR,Mazzolini K,Antonios N,Beck B,Protheroe C,Ochkur SI,Colbert D,Lacy P,Moqbel R,Appleton J,Lee NA,Lee JJ

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is common in Kuwait, a desert country, but the sensitizing allergens are uncertain. This study investigated the sensitizing allergens in Kuwaiti patients with extrinsic asthma. METHODS:A total of 553 asthmatics (male:female ratio: 1.4; mean age: 31.7 years [range 3-76 years]) and 112 matche...

journal_title：Allergy

authors： Ezeamuzie CI,Thomson MS,Al-Ali S,Dowaisan A,Khan M,Hijazi Z

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Occupational allergy forms an attractive model to study the development of allergic responses, as in some occupations it has a high incidence and develops quickly. In a cohort of starting laboratory animal workers, we previously found 20% sensitization to animal allergens within 2 years. METHODS:We compared...

journal_title：Allergy

authors： Krop EJ,van de Pol MA,Lutter R,Heederik DJ,Aalberse RC,van der Zee JS

更新日期：2010-10-01 00:00:00

abstract：:It is suggested that eosinophils (Eos) play an important role in the pathogenesis of bronchial asthma by releasing cytotoxic cationic eosinophil granule proteins and damaging bronchial epithelial cells. However, the exact nature of the actual inducer of eosinophil degranulation in vivo is unclear. We examined eosinoph...

journal_title：Allergy

authors： Takafuji S,Tadokoro K,Ito K

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:We hypothesized that, in south-west Poland, a 'rural' protective effect on atopy and respiratory allergies would be most pronounced among children but that at all ages would be stronger among those with a rural background. METHODS:A cross-sectional survey of the inhabitants (age >5 years, n = 1657) of Sobot...

journal_title：Allergy

authors： Sozanska B,Macneill SJ,Kajderowicz-Kowalik M,Danielewicz H,Wheatley M,Newman Taylor AJ,Boznanski A,Cullinan P

更新日期：2007-04-01 00:00:00

abstract：:708 unselected adolescents 15-17 years old were studied. They were physically examined, interviewed and skin prick tested with 12 common allergens. Questionnaires were distributed to the adolescents and their parents to investigate past and present symptoms and environmental influences. Emphasis was on the first year ...

journal_title：Allergy

authors： Suoniemi I,Björkstén F,Haahtela T

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:A cross-sectional retrospective study suggested a link between allergic diseases and Parkinson's disease. However, the temporal association between asthma and Parkinson's disease remains unknown. METHODS:From the Taiwan National Health Insurance Research Database, 10 455 patients who were diagnosed with ast...

journal_title：Allergy

authors： Cheng CM,Wu YH,Tsai SJ,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Tsai CF,Yang AC,Lin WC,Pan TL,Chang WH,Chen TJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The role of fibrocytes in chronic obstructive pulmonary disease (COPD) is unknown. We sought to enumerate blood and tissue fibrocytes in COPD and determine the association of blood fibrocytes with clinical features of disease. METHODS:Utilizing flow cytometry to identify circulating, collagen type 1+ cells,...

journal_title：Allergy

authors： Wright AK,Newby C,Hartley RA,Mistry V,Gupta S,Berair R,Roach KM,Saunders R,Thornton T,Shelley M,Edwards K,Barker B,Brightling CE

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains unclear. METHODS:FLG mutations R501X, 2282del4 and R2447X were genotyped in the Prevention and Incidence of Asthma and Mite Allergy birth cohort (n = 934) to evalu...

journal_title：Allergy

authors： Schuttelaar ML,Kerkhof M,Jonkman MF,Koppelman GH,Brunekreef B,de Jongste JC,Wijga A,McLean WH,Postma DS

更新日期：2009-12-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) occurs in up to one-third of the adult US population. Most affected individuals are either unaware of their condition or do not seek medical help, relying on nonprescription acid suppressants and antacids for relief. GERD, a common disorder of infancy, old age, and pregnancy, is ...

journal_title：Allergy

authors： Theodoropoulos DS,Lockey RF,Boyce HW Jr,Bukantz SC

更新日期：1999-07-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：:Occupational respiratory allergy to green coffee beans in coffee roastery workers is well established. I now report on a 50-year-old female atopic patient sensitized to the coffee plant used for indoor decoration. The symptoms were rhinitis and conjunctivitis on exposure to the plant. Investigation showed a positive s...

journal_title：Allergy

authors： Axelsson IG

更新日期：1994-12-01 00:00:00