Abstract:
:The aim of this study was to investigate possible effects of landscape design on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy from Uzbekistan where green areas have been changed during the last two decades by a State program. Sera from two different generations of Uzbek (n=58) and, for control purposes, from two generations of Austrian (n=58) patients were analyzed for IgE reactivity to 112 different micro-arrayed allergen molecules by ImmunoCAP ISAC technology. Changes in molecular IgE sensitization profiles to pollen allergens in the young vs the middle-aged Uzbek population were associated with replanting, whereas those in the Vienna populations reflected natural changes in plant growth. Our data indicate that anthropologic as well as natural changes in the biome may have effects on IgE sensitization profiles already from one to another generation.
journal_name
Allergyjournal_title
Allergyauthors
Garib V,Wollmann E,Djambekova G,Lemell P,Kmenta M,Berger U,Zieglmayer P,Valenta Rdoi
10.1111/all.13169subject
Has Abstractpub_date
2017-10-01 00:00:00pages
1579-1582issue
10eissn
0105-4538issn
1398-9995journal_volume
72pub_type
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