Possible effect of landscape design on IgE recognition profiles of two generations revealed with micro-arrayed allergens.

Abstract:

:The aim of this study was to investigate possible effects of landscape design on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy from Uzbekistan where green areas have been changed during the last two decades by a State program. Sera from two different generations of Uzbek (n=58) and, for control purposes, from two generations of Austrian (n=58) patients were analyzed for IgE reactivity to 112 different micro-arrayed allergen molecules by ImmunoCAP ISAC technology. Changes in molecular IgE sensitization profiles to pollen allergens in the young vs the middle-aged Uzbek population were associated with replanting, whereas those in the Vienna populations reflected natural changes in plant growth. Our data indicate that anthropologic as well as natural changes in the biome may have effects on IgE sensitization profiles already from one to another generation.

journal_name

Allergy

journal_title

Allergy

authors

Garib V,Wollmann E,Djambekova G,Lemell P,Kmenta M,Berger U,Zieglmayer P,Valenta R

doi

10.1111/all.13169

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

1579-1582

issue

10

eissn

0105-4538

issn

1398-9995

journal_volume

72

pub_type

杂志文章

相关文献

ALLERGY文献大全
  • Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis.

    abstract:BACKGROUND:Retrospective studies provide evidence that rhinitis is associated with more severe asthma. The aim of this study was to evaluate prospectively whether rhinitis is a predictor of increased asthma severity. METHODS:Five hundred and fifty-seven patients with severe asthma were enrolled. During 1 year of follo...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2007.01624.x

    authors: Ponte EV,Franco R,Nascimento HF,Souza-Machado A,Cunha S,Barreto ML,Naspitz C,Cruz AA

    更新日期:2008-05-01 00:00:00

  • Short-term venom immunotherapy induces desensitization of FcεRI-mediated basophil response.

    abstract:BACKGROUND:The precise immunological mechanisms for the early clinical protection of venom immunotherapy (VIT) have not yet been explained. Our aim was to evaluate whether high-affinity IgE receptor (FcεRI) and the related basophil function have a role in the induction of short-term VIT protection. METHODS:We included...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12044

    authors: Čelesnik N,Vesel T,Rijavec M,Šilar M,Eržen R,Košnik M,Kloft Žitnik SE,Avčin T,Korošec P

    更新日期:2012-12-01 00:00:00

  • Lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level.

    abstract:BACKGROUND:Environmental factors, including the intrauterine environment, can influence the risk of allergy development. In the present study, we investigated whether lifestyle and parental allergen sensitization status are reflected at gene expression level in the intrauterine environment. METHODS:  mRNA expression o...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2010.02328.x

    authors: Joerink M,Oortveld MA,Stenius F,Rindsjö E,Alm J,Scheynius A

    更新日期:2010-10-01 00:00:00

  • Food allergy endotype with high risk of severe anaphylaxis in children-Monosensitization to cashew 2S albumin Ana o 3.

    abstract:BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13810

    authors: Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

    更新日期:2019-10-01 00:00:00

  • Up-dosing with bilastine results in improved effectiveness in cold contact urticaria.

    abstract:BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/all.12171

    authors: Krause K,Spohr A,Zuberbier T,Church MK,Maurer M

    更新日期:2013-07-01 00:00:00

  • The non-specific enhancement of allergy. II. Precipitation of anaphylactic in vitro response capacity and serum IgE and IgG2a antibody synthesis in primed but non-responding rats by injection of alum.

    abstract::PVG rats given injections of 1 microgram ovalbumin (OA) together with 10 mg Silica gel failed to provide serosal mast cells or lung tissue with the capacity to release histamine on in vitro challenge with the antigen. However, if such animals were injected i.p. with 100 mg of alum (without any further antigen addition...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1983.tb01618.x

    authors: Bergstrand H,Andersson I,Nyström I,Pauwels R,Bazin H

    更新日期:1983-05-01 00:00:00

  • Full automation in allergy testing: measurement of specific IgE by the ENEA System.

    abstract:UNLABELLED:We evaluated the ENEA System, a fully automated instrument for the measurement of specific IgE antibodies. The instrument dispenses sera and reagents, incubates, washes, and reads and prints results automatically. The "core" of the instrument is the reactive unit called ACE (Allergy Chamber Enzymatic), which...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb01139.x

    authors: Plebani M,Faggian D,Borghesan F

    更新日期:1995-03-01 00:00:00

  • Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure.

    abstract:BACKGROUND:Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains unclear. METHODS:FLG mutations R501X, 2282del4 and R2447X were genotyped in the Prevention and Incidence of Asthma and Mite Allergy birth cohort (n = 934) to evalu...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2009.02080.x

    authors: Schuttelaar ML,Kerkhof M,Jonkman MF,Koppelman GH,Brunekreef B,de Jongste JC,Wijga A,McLean WH,Postma DS

    更新日期:2009-12-01 00:00:00

  • Level of asthma control and healthcare utilization in Latin America.

    abstract::The purpose of this study was to investigate whether uncontrolled asthma was associated with healthcare outcomes among Latin American patients with asthma. We used data from 2168 patients with asthma who participated in the 2011 Latin America Asthma Insights and Management (AIM) survey. Using Global Initiative for Ast...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12237

    authors: Gold LS,Montealegre F,Allen-Ramey FC,Jardim J,Smith N,Sansores R,Sullivan SD

    更新日期:2013-11-01 00:00:00

  • Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions.

    abstract::Delayed-type, T cell-mediated, drug hypersensitivity reactions are a serious unwanted manifestation of drug exposure that develops in a small percentage of the human population. Drugs and drug metabolites are known to interact directly and indirectly (through irreversible protein binding and processing to the derived ...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.14127

    authors: Naisbitt DJ,Olsson-Brown A,Gibson A,Meng X,Ogese MO,Tailor A,Thomson P

    更新日期:2020-04-01 00:00:00

  • New perspectives in asthma treatment.

    abstract::The recent advances in the knowledge of the basic mechanisms underlying asthmatic inflammation have significantly contributed to the delineation of new therapeutic perspectives for asthma. There are currently three main approaches to the development of novel antiasthma treatments: 1) improvement in existing classes of...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1034/j.1398-9995.2000.00510.x

    authors: Pelaia G,Vatrella A,Calabrese C,Mazzarella G,Marsico SA

    更新日期:2000-01-01 00:00:00

  • National clinical practice guidelines for allergen immunotherapy: An international assessment applying AGREE-II.

    abstract:BACKGROUND:Since 1988, numerous allergen immunotherapy guidelines (AIT-GLs) have been developed by national and international organizations to guide physicians in AIT. Even so, AIT is still severely underused. OBJECTIVE:To evaluate AIT-GLs with AGREE-II, developed in 2010 by McMaster University methodologists to compr...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13316

    authors: Larenas-Linnemann DES,Antolín-Amérigo D,Parisi C,Nakonechna A,Luna-Pech JA,Wedi B,Davila I,Gómez M,Levin M,Ortega Martell JA,Klimek L,Rosario N,Muraro AM,Agache I,Bousquet J,Sheikh A,EAACI International Societies Council.

    更新日期:2018-03-01 00:00:00

  • Lowered glutathione-peroxidase activity in asthmatic patients with food and aspirin intolerance.

    abstract::In analogy with findings from animal experiments, people with low glutathione-peroxidase (GSH-Px) activity could be expected to have altered sensitivities to effects of drugs, chemicals and possibly food. We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance. Ten of...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1986.tb00273.x

    authors: Malmgren R,Unge G,Zetterström O,Theorell H,de Wahl K

    更新日期:1986-01-01 00:00:00

  • The axis of the receptor for advanced glycation endproducts in asthma and allergic airway disease.

    abstract::Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of variable severity, which share a common complication of reversible airflow obstruction. Asthma is estimated to affect almost 400 million people worldwide, and nearly ten percent of asthmatics have what is considered "severe" disea...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.14600

    authors: Perkins TN,Donnell ML,Oury TD

    更新日期:2020-09-25 00:00:00

  • Effect of a bronchial provocation test with house-dust mite on blood eosinophilia, eosinophil cationic protein, soluble interleukin-2 receptor, and interleukin-6 in asthmatic children.

    abstract::Eighteen children with perennial asthma and allergy to house-dust mite (HDM) underwent a bronchial challenge with HDM. Before and 24 h after the test, a venous blood sample was taken to determine levels of eosinophils, eosinophil cationic protein (ECP), soluble interleukin-2 receptor (IL-2R), and interleukin-6 (IL-6)....

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1993.tb00742.x

    authors: Van Bever HP,Moens MM,Bridts CH,De Clerck LS,Mertens AV,Bosmans E,Stevens WJ

    更新日期:1993-08-01 00:00:00

  • Allergy to latex condoms.

    abstract::This study delineates the prevalence of reactions to condoms among latex-allergic patients seen in allergy consultation services since 1987. Questionnaires were mailed to 374 patients previously found to have clinically significant allergy to latex. Of these, only 238 completed the questionnaire. The respondents we...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1998.tb03827.x

    authors: Levy DA,Khouader S,Leynadier F

    更新日期:1998-11-01 00:00:00

  • Management of ocular allergy.

    abstract::The treatment and management of ocular allergy (OA) remain a major concern for different specialties, including allergists, ophthalmologists, primary care physicians, rhinologists, pediatricians, dermatologists, clinical immunologists, and pharmacists. We performed a systematic review of all relevant publications in M...

    journal_title:Allergy

    pub_type: 杂志文章,meta分析

    doi:10.1111/all.13786

    authors: Leonardi A,Silva D,Perez Formigo D,Bozkurt B,Sharma V,Allegri P,Rondon C,Calder V,Ryan D,Kowalski ML,Delgado L,Doan S,Fauquert JL

    更新日期:2019-09-01 00:00:00

  • Is the hygiene hypothesis still a viable explanation for the increased prevalence of asthma?

    abstract::The hygiene hypothesis states that a reduced exposure to allergens in early life is solely implicated in the growing propensity for allergy sensitization. Important elements of the hypothesis include helminth infection, exposure to endotoxins, exposure to pets and growing up on a farm. However, the hygiene hypothesis ...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.2005.00854.x

    authors: Platts-Mills TA,Erwin E,Heymann P,Woodfolk J

    更新日期:2005-01-01 00:00:00

  • Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults.

    abstract::In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily. The post-exercise percentage fall in FEV1 after SCG but not after ketotifen was significantly smaller than after placebo. A 1-week treatme...

    journal_title:Allergy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.1987.tb02215.x

    authors: Tan WC,Lim TK

    更新日期:1987-05-01 00:00:00

  • Phthalates suppress type I interferon in human plasmacytoid dendritic cells via epigenetic regulation.

    abstract:BACKGROUND:Exposure to environmental endocrine-disrupting chemicals (EDCs) is associated with allergy, chronic inflammation, and immunodeficiency. Phthalates, the common EDCs used in plastic industry, may act as adjuvants to disrupt immune system and enhance allergy. Plasmacytoid DCs (pDCs) are predominant cells secret...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12162

    authors: Kuo CH,Hsieh CC,Kuo HF,Huang MY,Yang SN,Chen LC,Huang SK,Hung CH

    更新日期:2013-07-01 00:00:00

  • Streptomycin-induced anaphylactic reaction during in vitro fertilization (IVF).

    abstract::Indications for in vitro fertilization (IVF) have been cautiously extended over the years. IVF is usually considered to be a technically complex method with only minimal side-effects. We report the case of a woman who developed an anaphylactic reaction during IVF immediately after the embryo transfer. ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1994.tb02288.x

    authors: Abeck D,Kuwert C,Segnini-Torres M,Przybilla B,Ring J

    更新日期:1994-05-01 00:00:00

  • Asthma prediction in school children; the value of combined IgE-antibodies and obstructive airways disease severity score.

    abstract:BACKGROUND:Allergic sensitisation increases the risk for asthma development. In this prospective birth cohort (Environment and Childhood Asthma) study, we hypothesized that combining quantitative measures of IgE antibodies (Sigma-IgE) and Severity score of obstructive airways disease (OAD) at 2 years of age (Severity s...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2010.02344.x

    authors: Lødrup Carlsen KC,Söderström L,Mowinckel P,Håland G,Pettersen M,Munthe Kaas MC,Devulapalli CS,Buchmann M,Ahlstedt S,Carlsen KH

    更新日期:2010-09-01 00:00:00

  • Food-induced cutaneous adverse reactions.

    abstract::The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.1998.tb04983.x

    authors: Wüthrich B

    更新日期:1998-01-01 00:00:00

  • Systemic contact dermatitis to copper-containing IUD.

    abstract::Although copper sulfate can cause systemic contact dermatitis, few such cases have been recorded among copper-releasing IUD users. Reported in this paper is a case of endometritis and urticaria-angioedema syndrome in a 32-year-old user of a copper IUD. Widespread urticaria, as well as angioedema of the eyelids and t...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1996.tb04688.x

    authors: Purello D'Ambrosio F,Ricciardi L,Isola S,Gangemi S,Cilia M,Levanti C,Marcazzò A

    更新日期:1996-09-01 00:00:00

  • Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma.

    abstract::Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the approach to patients with allergic diseases encompasses novel developments in the area of personalized medicine, disease phenotyping and endotyping, and the develo...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.14582

    authors: Breiteneder H,Peng YQ,Agache I,Diamant Z,Eiwegger T,Fokkens WJ,Traidl-Hoffmann C,Nadeau K,O'Hehir RE,O'Mahony L,Pfaar O,Torres MJ,Wang DY,Zhang L,Akdis CA

    更新日期:2020-09-07 00:00:00

  • Non-specific histamine release activity of busereline, LH-releasing hormone.

    abstract::Busereline acetate is an LH-RH agonist that was found to induce local reactions at the injection site or generalized minor skin reactions in some patients. Since these reactions may represent the first reaction of systemic anaphylaxis, we tested the non-specific histamine releasing activity of this drug by intradermal...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1988.tb01634.x

    authors: Bousquet J,Hédon B,Hejjaoui A,Chanal I,Michel FB

    更新日期:1988-10-01 00:00:00

  • Hypersensitivity to cefuroxime with good tolerance to other betalactams.

    abstract::A 60-year-old man developed an anaphylactic reaction immediately after administration of intramuscular sodium cefuroxime. By means of oral controlled challenge, the reaction was reproduced with a smaller dose of cefuroxime axetil. Cross-reactivity with other betalactam antibiotics was ruled out by in vivo tests. This ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb01160.x

    authors: Marcos Bravo C,Luna Ortiz I,González Vázquez R

    更新日期:1995-04-01 00:00:00

  • Evidence for an asthma risk locus on chromosome Xp: a replication linkage study.

    abstract:BACKGROUND:Asthma is a complex genetic disorder characterized by chronic inflammation in the airways. Identification of genetic risk factors for asthma has been complicated due to genetic heterogeneity and influence from environmental risk factors. Despite the fact that multiple genetic linkage studies have been carrie...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2008.01699.x

    authors: Brasch-Andersen C,Møller MU,Haagerup A,Vestbo J,Kruse TA

    更新日期:2008-09-01 00:00:00

  • Marker antigens to assess exposure to molds and their allergens. II. Alternaria alternata.

    abstract::The estimation of exposure to molds and their products in the indoor environment, which may lead to the occurrence of allergies or respiratory complaints, by means of enumeration of viable parts is inadequate. Therefore, other methods must be developed. When grown under various circumstances (22 degrees C and 30 degre...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:

    authors: Wijnands LM,Deisz WD,van Leusden FM

    更新日期:2000-09-01 00:00:00

  • Elevated levels of peripheral-blood, naturally occurring aliphatic polyamines in bronchial asthmatic patients with active symptoms.

    abstract::The levels of peripheral-blood, naturally occurring aliphatic polyamines, such as putrescine, spermidine, and spermine, from 21 bronchial asthmatic patients (11 atopics and 10 nonatopics) were measured by postcolumn derivatization high-performance liquid chromatography analysis. None of the patients, except the 44-yea...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1992.tb02388.x

    authors: Kurosawa M,Shimizu Y,Tsukagoshi H,Ueki M

    更新日期:1992-12-01 00:00:00