Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis.

abstract：BACKGROUND:Whereas recent studies underlie the fundamental importance of the CC chemokine receptor 3 (CCR3) for the recruitment of eosinophils in allergic diseases, controversial data exist about the relevance of CCR1 on eosinophils. Therefore, the purpose of this study was to investigate the expression and regulation ...

journal_title：Allergy

authors： Elsner J,Dulkys Y,Gupta S,Escher SE,Forssmann WG,Kapp A,Forssmann U

更新日期：2005-11-01 00:00:00

abstract：:It is debatable whether beta 2-receptor agonists produce antiallergic effects in human airways. This question has been addressed in the present study by examination of both mast-cell indices and the physiologic response to allergen challenge in human nasal airways. Twelve asymptomatic patients with seasonal allergic r...

journal_title：Allergy

authors： Svensson C,Greiff L,Andersson M,Alkner U,Grönneberg R,Persson CG

更新日期：1995-11-01 00:00:00

abstract：:Overproduction of periostin, an IL-13-inducible matricellular protein, despite corticosteroid treatment is thought to be involved in the chronicity of allergic inflammation seen in corticosteroid-refractory tissue fibrosis. Therefore, we hypothesized that some tissue cells must produce periostin in a corticosteroid-in...

journal_title：Allergy

authors： Shoda T,Futamura K,Kobayashi F,Saito H,Matsumoto K,Matsuda A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Children with spina bifida (SB) are exposed to latex soon after birth during bladder catheterization, rectal disimpaction, and multiple surgical procedures. IgE-mediated latex-allergic reactions have been reported recently in these children. Our study was designed to assess the prevalence of allergic reactio...

journal_title：Allergy

authors： Kattan H,Harfi HA,Tipirneni P

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Abnormalities, including bronchiectasis, that are detectable on high-resolution computed tomography (HRCT) have been associated with severe asthma. Bronchiectasis is associated with the diagnosis of allergic bronchopulmonary aspergillosis (ABPA), which also occurs in patients with severe asthma. We sought to...

journal_title：Allergy

authors： Menzies D,Holmes L,McCumesky G,Prys-Picard C,Niven R

更新日期：2011-05-01 00:00:00

abstract：:Dose- and pH- dependent carbodiimide-mediated coupling of Penicillin-G to polystyrene microtiter-plates that leaves the beta-lactam ring unchanged is described. A new ELISA method was developed using Penicillin-G coated plates. The binding of 3 different monoclonal antibodies as well as human IgG antibodies of the IgG...

journal_title：Allergy

authors： Klein GF,Stanzl U,Fritsch PO,Varga JM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：:Application of strict diagnostic criteria to celiac disease has led to the realization that there is a wide clinical spectrum within this disease. Normally there are immune reactions to dietary proteins, particularly secretory antibodies of IgA class, low titers of serum antibody and specific down-regulation of IgE an...

journal_title：Allergy

authors： Ferguson A

更新日期：1995-01-01 00:00:00

abstract：:In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily. The post-exercise percentage fall in FEV1 after SCG but not after ketotifen was significantly smaller than after placebo. A 1-week treatme...

journal_title：Allergy

authors： Tan WC,Lim TK

更新日期：1987-05-01 00:00:00

abstract：:We challenged in a double-blind manner 46 pollen-allergic patients with 30 g of honey and another 32 patients with a placebo (30 g of syrup). Minor, mostly subjective, symptoms were seen in or reported by 26% of those challenged with honey and 41% of those challenged with placebo. In no case could the symptoms with ce...

journal_title：Allergy

authors： Kiistala R,Hannuksela M,Mäkinen-Kiljunen S,Niinimäki A,Haahtela T

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Kiwifruit is an important cause of food allergy. A high amount of a protein with a molecular mass compatible with that of Bet v 1 was observed in the kiwifruit extract. OBJECTIVE:To identify and characterize kirola, the 17-kDa protein of green kiwifruit (Act d 11). METHODS:Act d 11 was purified from green ...

journal_title：Allergy

authors： D'Avino R,Bernardi ML,Wallner M,Palazzo P,Camardella L,Tuppo L,Alessandri C,Breiteneder H,Ferreira F,Ciardiello MA,Mari A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:There are large differences in the prevalence of atopic disease between urban and rural areas of developing countries, without good explanation. Diet has been associated with atopic disease, but studies of specific nutrients are contradictory, cross-sectional studies often being unsupported by trials. We inv...

journal_title：Allergy

authors： Hooper R,Calvert J,Thompson RL,Deetlefs ME,Burney P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire. METHODS:To validate questions used in a country-wide study among university students aged 18-25 year...

journal_title：Allergy

authors： Kilpeläinen M,Terho EO,Helenius H,Koskenvuo M

更新日期：2001-05-01 00:00:00

abstract：:A shared approach to decision-making framework has been suggested for chronic disease management especially where multiple treatment options exist. Shared decision-making (SDM) requires that both physician and patients are actively engaged in the decision-making process, including information exchange; expressing trea...

journal_title：Allergy

authors： Pollard S,Bansback N,FitzGerld JM,Bryan S

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs) with stable FOXP3 expression are characterized by a specific demethylated region in the FOXP3 gene (Treg-specific demethylated region, TSDR). The aim of this study was to analyse the influence of prenatal factors on cord blood Treg numbers, as detected by changes in the TSDR demeth...

journal_title：Allergy

authors： Hinz D,Bauer M,Röder S,Olek S,Huehn J,Sack U,Borte M,Simon JC,Lehmann I,Herberth G,LINA study group.

更新日期：2012-03-01 00:00:00

abstract：:Ketotifen is marketed throughout the world as an antiallergy drug, but whether it affects infiltration of inflammatory cells into airway mucosa is not known. We studied the effects of ketotifen on symptoms, pulmonary function, and airway inflammation in 25 patients with atopic asthma. Patients took ketotifen (1 mg twi...

journal_title：Allergy

authors： Hoshino M,Nakamura Y,Shin Z,Fukushima Y

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

journal_title：Allergy

authors： Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

更新日期：2020-04-01 00:00:00

abstract：:The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...

journal_title：Allergy

authors： Odelram H,Björkstén B,Chan SC,Hanifin JM,Kjellman NI

更新日期：1994-09-01 00:00:00

abstract：:In studies on atopic dermatitis (AD), different scoring systems are used to evaluate the severity of the disease. The objective of this study was to investigate agreement between observers in the assessment of the overall severity of AD, and interobserver variation in the assessment of severity of AD for each scoring ...

journal_title：Allergy

authors： Sprikkelman AB,Tupker RA,Burgerhof H,Schouten JP,Brand PL,Heymans HS,van Aalderen WM

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:We report on a 21-year-old atopic woman who developed urticaria, angioedema of the face, and wheezy dyspnea shortly after drinking beer and after eating a corn-made snack. METHODS:Skin prick tests and specific IgE determinations to beer ingredients and cereal extracts were performed. Immunoblotting inhibiti...

journal_title：Allergy

authors： Figueredo E,Quirce S,del Amo A,Cuesta J,Arrieta I,Lahoz C,Sastre J

更新日期：1999-06-01 00:00:00

abstract：:Daily sensitization of SPF BNxWi/Fu rats with ovalbumin (OA) in aerosol during 2-week periods with a 4-week interval resulted after 7 weeks in IgE, IgA and IgG antibodies in serum and bronchial fluid. After cultivation of the regional, axillary, brachial and mediastinal (ABM) lymph node cells, IgE antibodies were foun...

journal_title：Allergy

authors： Ahlstedt S,Björkstén B,Hesselmar B,Nygren H,Alving K,Olaisson E

更新日期：1985-05-01 00:00:00

abstract：:We investigated whether exine-free pollen allergen particles exist together with the intact pollen grains of Japanese cedar (Cryptomeria japonica) in the air during the pollen season in Yamagata City. First, we separated the allergen particles in an Andersen multi-stage air-sampler according to their aerodynamic diame...

journal_title：Allergy

authors： Takahashi Y,Sakaguchi M,Inouye S,Miyazawa H,Imaoka K,Katagiri S

更新日期：1991-11-01 00:00:00

abstract：:Basophil histamine release was studied in leukocyte suspensions from normal individuals and from patients allergic to house dust mite or birch pollen. Mediator release caused by IgE-mediated reactions was examined by stimulating the cells with anti-IgE or specific antigens, and the calcium ionophore A23187 was used fo...

journal_title：Allergy

authors： Clementsen P,Norn S,Kristensen KS,Hannoun C

更新日期：1990-08-01 00:00:00

abstract：:The aim of this study was to assess the ability of the H1-receptor antagonist loratadine to modify anti-IgE-induced cutaneous wheal-and-flare and late-phase reactions (WFR and LPR), as well as histamine release and leukocyte accumulation in skin chambers. For this purpose, 10 atopics with allergic rhinitis were entere...

journal_title：Allergy

authors： Roquet A,Raud J,Halldén G,van Hage-Hamsten M,Hed J,Hansson LO,Zetterström O,Grönneberg R

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The precise immunological mechanisms for the early clinical protection of venom immunotherapy (VIT) have not yet been explained. Our aim was to evaluate whether high-affinity IgE receptor (FcεRI) and the related basophil function have a role in the induction of short-term VIT protection. METHODS:We included...

journal_title：Allergy

authors： Čelesnik N,Vesel T,Rijavec M,Šilar M,Eržen R,Košnik M,Kloft Žitnik SE,Avčin T,Korošec P

更新日期：2012-12-01 00:00:00

abstract：:This study was conducted to evaluate how bronchial responsiveness to direct and indirect stimuli relate to nitric oxide producing airway inflammation, and whether the relationship differs between atopic and nonatopic patients with various degrees of bronchial hyperresponsiveness and airway inflammation in a group of o...

journal_title：Allergy

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Sovijärvi AR

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：:Oral immunotherapy (IT) was evaluated in a pilot study in two centres in children aged 8-15 years with allergic rhinoconjunctivitis. High doses (up to 20 X 10(6) BU monthly) of a defined freeze-dried birch pollen extract administered in enteric-coated gelatine capsules were given either daily for seven consecutive day...

journal_title：Allergy

authors： Björkstén B,Möller C,Broberger U,Ahlstedt S,Dreborg S,Johansson SG,Juto P,Lanner A

更新日期：1986-05-01 00:00:00

abstract：:Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma. PubMed, Embase ...

journal_title：Allergy

authors： Agache I,Beltran J,Akdis C,Akdis M,Canelo-Aybar C,Canonica GW,Casale T,Chivato T,Corren J,Del Giacco S,Eiwegger T,Firinu D,Gern JE,Hamelmann E,Hanania N,Mäkelä M,Hernández-Martín I,Nair P,O'Mahony L,Papadopoulos NG

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Partial mattress encasing was found to be effective in reducing exposure to mite allergen in our previous investigation. We aimed to compare the short-term efficacy of partial and complete mattress encasing and to study mite-allergen levels within these mattresses. METHODS:Thirty-one mattresses with high mi...

journal_title：Allergy

authors： Vichyanond P,Uthaisangsook S,Ruangruk S,Malainual N

更新日期：1999-07-01 00:00:00