Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions.

abstract：:Cocksfoot/orchard grass (Dactylis glomerata) anther cDNA clones encoding the group II allergen Dac g II were previously isolated on the basis of immunoreactivity of human, rabbit, and murine antibodies with a 24-kDa protein expressed as a fusion protein with beta-galactosidase. Nucleotide sequencing reveals an open re...

journal_title：Allergy

authors： Roberts AM,Bevan LJ,Flora PS,Jepson I,Walker MR

更新日期：1993-11-01 00:00:00

abstract：:The prevalence and specificity of naturally occurring human IgA anti-IgE autoantibodies (a-E Ab) were studied by ELISA with anti-IgA monoclonal antibodies (mAb) and a purified myeloma IgE as solid-phase protein, i.e., IgE-DES(kappa). Such detected IgA a-E Ab were common among adults, and significantly increased geomet...

journal_title：Allergy

authors： Magnusson CG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Nasal congestion is the predominant symptom in perennial allergic rhinitis (PAR), and it seems to be mainly related to the late-phase inflammatory events. The present pilot study aimed to evaluate the therapeutic effect exerted by fexofenadine in patients with PAR due to mite allergy. METHODS:This study was...

journal_title：Allergy

authors： Ciprandi G,Cosentino C,Milanese M,Mondino C,Canonica GW

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. METHODS:We performed oral food challenges in 21 apple-allergic individuals with Elstar apples which had undergone gene ...

journal_title：Allergy

authors： Dubois AE,Pagliarani G,Brouwer RM,Kollen BJ,Dragsted LO,Eriksen FD,Callesen O,Gilissen LJ,Krens FA,Visser RG,Smulders MJ,Vlieg-Boerstra BJ,Flokstra-de Blok BJ,van de Weg WE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs) with stable FOXP3 expression are characterized by a specific demethylated region in the FOXP3 gene (Treg-specific demethylated region, TSDR). The aim of this study was to analyse the influence of prenatal factors on cord blood Treg numbers, as detected by changes in the TSDR demeth...

journal_title：Allergy

authors： Hinz D,Bauer M,Röder S,Olek S,Huehn J,Sack U,Borte M,Simon JC,Lehmann I,Herberth G,LINA study group.

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Occurrence, elicitors and treatment of severe allergic reactions are recognized and reported differently between countries. We aimed to collect standardized data throughout Europe on anaphylaxis referred for diagnosis and counselling. METHODS:Tertiary allergy, dermatology and paediatric units in 10 European...

journal_title：Allergy

authors： Worm M,Moneret-Vautrin A,Scherer K,Lang R,Fernandez-Rivas M,Cardona V,Kowalski ML,Jutel M,Poziomkowska-Gesicka I,Papadopoulos NG,Beyer K,Mustakov T,Christoff G,Bilò MB,Muraro A,Hourihane JO,Grabenhenrich LB

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Aspirin, a cyclo-oxygenase (COX)-1 and COX-2 inhibitor, is the antiplatelet drug of choice to prevent serious vascular events. Adverse reactions to aspirin are frequent particularly among patients with asthma, chronic rhinosinusitis and nasal polyps. COX-1 inhibitors but not COX-2 inhibitors precipi...

journal_title：Allergy

authors： Fraj J,Valero A,Vives R,Pérez I,Borja J,Izquierdo I,Picado C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Up to 10% of the patients in whom suspected betalactam hypersensitivity (HS) has been excluded by skin and challenge tests report suspected allergic reactions during subsequent treatments with the same or very similar betalactams. It has been suggested that the reactions may result from a resensitization ind...

journal_title：Allergy

authors： Ponvert C,Weilenmann C,Wassenberg J,Walecki P,Bourgeois ML,de Blic J,Scheinmann P

更新日期：2007-01-01 00:00:00

abstract：:A study was undertaken to see whether the principal airborne fungi in the North-East Netherlands were also found to be the most reactive in skin testing. Atmospheric samples were taken weekly with the Andersen sampler, from April 1981, up to and including, June 1983. At the same time skin tests of 833 patients referre...

journal_title：Allergy

authors： Beaumont F,Kauffman HF,de Monchy JG,Sluiter HJ,de Vries K

更新日期：1985-04-01 00:00:00

abstract：:The estimation of exposure to molds and their products in the indoor environment, which may lead to the occurrence of allergies or respiratory complaints, by means of enumeration of viable parts is inadequate. Therefore, other methods must be developed. When grown under various circumstances (22 degrees C and 30 degre...

journal_title：Allergy

authors： Wijnands LM,Deisz WD,van Leusden FM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：:This guideline is the result of a consensus reached during a panel discussion at the 2nd International Consensus Meeting on Urticaria, Urticaria 2004, a joint initiative of the European Academy of Allergology and Clinical Immunology Dermatology Section and the European Union (EU)-funded network of excellence, GA2LEN. ...

journal_title：Allergy

authors： Zuberbier T,Bindslev-Jensen C,Canonica W,Grattan CE,Greaves MW,Henz BM,Kapp A,Kozel MM,Maurer M,Merk HF,Schäfer T,Simon D,Vena GA,Wedi B,EAACI\/GA2LEN\/EDF.

更新日期：2006-03-01 00:00:00

abstract：:The parents of 3649 Finnish children and adolescents were interviewed in 1980 to evaluate the prevalence of bronchial asthma, allergic rhinitis and atopic dermatitis. The same group was interviewed 6 years later to determine the incidence of new cases of bronchial asthma in the 1980s. Age- and sex-matched samples were...

journal_title：Allergy

authors： Pöysä L,Korppi M,Pietikäinen M,Remes K,Juntunen-Backman K

更新日期：1991-04-01 00:00:00

abstract：:A sustained release preparation of terbutaline sulphate has been formulated (Bricanyl depot tablets) in order to extend the duration and accordingly change the dosage regimen to twice a day. This presentation gives a summary of a clinical trial performed in order to study effect and side effects of terbutaline depot t...

journal_title：Allergy

authors： Taudorf E,Bundgaard A,Fagerström PO,Weeke E,Weeke B

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Hippo-Yes-associated protein (YAP) pathway plays an important role in epithelial cell proliferation and development. However, its possible role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unknown. We aim to investigate it on nasal epithelial proliferation and remodeling in CRSwNP. METHODS:T...

journal_title：Allergy

authors： Deng H,Sun Y,Wang W,Li M,Yuan T,Kong W,Huang X,Long Z,Chen Z,Wang D,Yang Q

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Aluminium (ALUM) is used as experimental and clinical adjuvant for parenteral vaccine formulation. It is also contained in anti-acid drugs like sucralfate (SUC). These anti-acids have been shown to cause sensitization to food proteins via elevation of the gastric pH. The aim of this study was to assess the o...

journal_title：Allergy

authors： Brunner R,Wallmann J,Szalai K,Karagiannis P,Altmeppen H,Riemer AB,Jensen-Jarolim E,Pali-Schöll I

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Hereditary angioedema (HAE), type I and II, is an autosomal dominant disease with deficiency of functional C1 inhibitor protein causing episodic swellings of skin, mucosa and viscera. HAE is a genetically heterogeneous disease with more than 200 different mutations in the SERPING1 gene. A genotype-phenotype ...

journal_title：Allergy

authors： Bygum A,Fagerberg CR,Ponard D,Monnier N,Lunardi J,Drouet C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:With the current increasing incidence of allergies worldwide, new treatments showing efficacy and long term safety are needed for chronic conditions such as persistent allergic rhinitis (PER). New generation H1-antihistamines have demonstrated anti-allergic properties, which could possibly enhance their effe...

journal_title：Allergy

authors： Fantin S,Maspero J,Bisbal C,Agache I,Donado E,Borja J,Mola O,Izquierdo I,international Rupatadine study group.

更新日期：2008-07-01 00:00:00

abstract：:This update aimed to review the new evidence available to support or refute prior Allergic Rhinitis and its Impact on Asthma (ARIA) statements. A Medline search of publications between 2000 and 2005 was conducted, with articles selected by experts. New evidence supports previous ARIA statements, such as: (i) allergic ...

journal_title：Allergy

authors： Cruz AA,Popov T,Pawankar R,Annesi-Maesano I,Fokkens W,Kemp J,Ohta K,Price D,Bousquet J,ARIA Initiative Scientific Committee.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Subjective symptoms after food challenges are difficult to interpret and no standard is available. We discuss a strategy for how to interpret a diary. Furthermore, the interobserver reliability is evaluated. METHODS:Diaries for 32 patients with subjective symptoms were used. The diaries were re-evaluated wi...

journal_title：Allergy

authors： Gellerstedt M,Magnusson J,Gråjö U,Ahlstedt S,Bengtsson U

更新日期：2004-03-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) occurs in up to one-third of the adult US population. Most affected individuals are either unaware of their condition or do not seek medical help, relying on nonprescription acid suppressants and antacids for relief. GERD, a common disorder of infancy, old age, and pregnancy, is ...

journal_title：Allergy

authors： Theodoropoulos DS,Lockey RF,Boyce HW Jr,Bukantz SC

更新日期：1999-07-01 00:00:00

abstract：:The objective was to present a case of periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), summarize the medical literature on PFAPA, review the differential diagnosis and suggest a diagnostic approach to periodic fevers in children. A PubMed search was conducted for all case reports an...

journal_title：Allergy

authors： Lierl M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:  Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP). However, the mechanism of inflammation in CRS has still not been fully elucidated. The aim of the s...

journal_title：Allergy

authors： Keswani A,Chustz RT,Suh L,Carter R,Peters AT,Tan BK,Chandra R,Kim SH,Azam T,Dinarello CA,Kern RC,Schleimer RP,Kato A

更新日期：2012-01-01 00:00:00

abstract：:Administration of allergen-specific immunotherapy by the oral route, sublingual immunotherapy (SLIT), has been shown to be effective, with an improved safety profile compared with subcutaneous administration. However, the precise mechanisms underlying the induction of immune tolerance by SLIT remain unclear. Contact o...

journal_title：Allergy

authors： Akdis CA,Barlan IB,Bahceciler N,Akdis M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:IgE-independent (pseudoallergic) reactions to food and food ingredients are common in a subgroup of adult patients with chronic urticaria, who have daily spontaneous occurrence of wheals. However, for children with chronic urticaria (duration longer than 6 weeks, no physical influence), no data on the import...

journal_title：Allergy

authors： Ehlers I,Niggemann B,Binder C,Zuberbier T

更新日期：1998-11-01 00:00:00

abstract：:The yeast Pityrosporum orbiculare (P. orbiculare) is a member of the normal human cutaneous flora, but it is also associated with several clinical manifestations of the skin. We have previously observed IgE-binding components in P. orbiculare extracts, using sera from patients with atopic dermatitis. In the present st...

journal_title：Allergy

authors： Zargari A,Härfast B,Johansson S,Johansson SG,Scheynius A

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The effectiveness of acaricides in homes is controversial. OBJECTIVE:To determine whether disodium octaborate tetrahydrate (DOT) combined with vacuuming lowers dust mite numbers and their allergens in carpets and sofas. METHODS:A 6-month study was carried out with 93 homes, which were randomized into three...

journal_title：Allergy

authors： Codina R,Lockey RF,Diwadkar R,Mobly LL,Godfrey S

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The diagnosis of allergic reactions to drugs is difficult. Most skin tests are not standardized, and in vitro tests are needed to avoid provocation tests. Cross-linking of IgE on basophils is known to cause the release of both cysteinyl leukotriene (Cys-LT) and histamine. We aimed to evaluate the diagnostic ...

journal_title：Allergy

authors： Lebel B,Messaad D,Kvedariene V,Rongier M,Bousquet J,Demoly P

更新日期：2001-07-01 00:00:00

abstract：:This study evaluated the risk factors for developing allergic reactions to alternative drugs such as acetaminophen and nimesulide in 367 patients intolerant of nonsteroidal anti-inflammatory drugs (NSAID) compared to 243 healthy controls. All subjects were given test doses (TD) of acetaminophen and nimesulide, and age...

journal_title：Allergy

authors： Pastorello EA,Zara C,Riario-Sforza GG,Pravettoni V,Incorvaia C

更新日期：1998-09-01 00:00:00