Interpretation of subjective symptoms in double-blind placebo-controlled food challenges - interobserver reliability.

Abstract:

BACKGROUND:Subjective symptoms after food challenges are difficult to interpret and no standard is available. We discuss a strategy for how to interpret a diary. Furthermore, the interobserver reliability is evaluated. METHODS:Diaries for 32 patients with subjective symptoms were used. The diaries were re-evaluated with a predefined strategy by three independent observers. RESULTS:The proportion of positives was 21.9% among the old diagnoses, according to the new approach 34.4% (observers I and II) and 37.5% (observer III) were positive. The new approach had high interobserver reliability (97 and 100%). CONCLUSIONS:The proportion of positives depends on how subjective symptoms are interpreted. Interpretations of subjective symptoms in diaries could be made with high interobserver reliability.

journal_name

Allergy

journal_title

Allergy

authors

Gellerstedt M,Magnusson J,Gråjö U,Ahlstedt S,Bengtsson U

doi

10.1111/j.1398-9995.2003.00437.x

keywords:

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

354-6

issue

3

eissn

0105-4538

issn

1398-9995

pii

ALL437

journal_volume

59

pub_type

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