Mutational spectrum and phenotypes in Danish families with hereditary angioedema because of C1 inhibitor deficiency.

abstract：:The use of recombinant DNA techniques for the study of allergenicity of proteins is a viable, and in many ways a preferred, alternative to the traditional procedures of protein purification, digestion and analysis of peptides for both allergenicity and amino acid sequence. The process of protein purification can be di...

journal_title：Allergy

authors： Baldo BA,Donovan GR

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis is commonly divided into seasonal and perennial rhinitis. The recent Allergic Rhinitis and its Impact on Asthma (ARIA) workshop proposes to replace these terms by intermittent vs persistent rhinitis. METHODS:In order to test the new ARIA classification against the classical one used in med...

journal_title：Allergy

authors： Demoly P,Allaert FA,Lecasble M,Bousquet J,PRAGMA.

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Although airway hyperresponsiveness (AHR) is a characteristic feature of asthma, it is also frequently present in allergic rhinitis (AR). However, the pathogenesis of AHR is unclear and the roles of cytokines in the airway have not been well established in AR. We sought to compare cytokine mRNA levels in the...

journal_title：Allergy

authors： Sohn SW,Lee HS,Park HW,Chang YS,Kim YK,Cho SH,Kim YY,Min KU

更新日期：2008-03-01 00:00:00

abstract：:The bioavailability of three different theophylline tablets (microcrystallinic theophylline, Theolair, Nuelin, 3M Riker), choline theophyllinate as a new film-coated tablet (Teovent, Ferrosan, Sweden) and theophyllaminopropanol (Oxyphylline, Draco, Sweden) was investigated in eight adult asthmatics and a randomized, d...

journal_title：Allergy

authors： Svedmyr K,Mellstrand T,Svedmyr N

更新日期：1982-02-01 00:00:00

abstract：:The red cell-linked antigen-antiglobulin reaction (RCLAAR) with stearoyldextran-coated erythrocytes was used to characterize the immunoglobulin (Ig) classes and IgG subclasses of dextran reactive antibodies (DRA) in 27 dextran reactors (DR) and 96 on reactors (DNR). High titres of dextran reactive IgG were regularly f...

journal_title：Allergy

authors： Kraft D,Hedin H,Richter W,Scheiner O,Rumpold H,Devey ME

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause. Indeed, recent evidence indicates that bacteria-derived extracellular vesicles (EV) appear to be an important causative agent of inflammatory diseases. Here, we ...

journal_title：Allergy

authors： Choi EB,Hong SW,Kim DK,Jeon SG,Kim KR,Cho SH,Gho YS,Jee YK,Kim YK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:We report on a 21-year-old atopic woman who developed urticaria, angioedema of the face, and wheezy dyspnea shortly after drinking beer and after eating a corn-made snack. METHODS:Skin prick tests and specific IgE determinations to beer ingredients and cereal extracts were performed. Immunoblotting inhibiti...

journal_title：Allergy

authors： Figueredo E,Quirce S,del Amo A,Cuesta J,Arrieta I,Lahoz C,Sastre J

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Little is known about the diagnostic accuracy of atopy patch tests (APT) in the clinical practice of pediatric gastroenterology. Moreover, APTs containing purified food extracts have recently become available, but their diagnostic accuracy is largely undefined. PATIENTS AND METHODS:We evaluated the diagnost...

journal_title：Allergy

authors： Canani RB,Ruotolo S,Auricchio L,Caldore M,Porcaro F,Manguso F,Terrin G,Troncone R

更新日期：2007-07-01 00:00:00

abstract：:Quantiative immunoelectrophoresis used for the analysis of a dialysed, centrifuged and freeze-dried extract from cow hair and dander revealed 17 antigens. Five of these were identified as serum proteins. Partial identity to antigens of serum and extract from hair and dander of goat, sheep, swine, horse, dog, cat and g...

journal_title：Allergy

authors： Prahl P,Weeke B,Løwenstein H

更新日期：1978-10-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：:The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

journal_title：Allergy

authors： Wüthrich B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Management of atopic dermatitis (AD) requires judging the symptoms of local skin lesions and prescribing a suitable treatment. However, no method has been established in which objective measures can be used to evaluate the severity of local symptoms. We established a method for measuring thymus and activatio...

journal_title：Allergy

authors： Morita E,Takahashi H,Niihara H,Dekio I,Sumikawa Y,Murakami Y,Matsunaka H

更新日期：2010-09-01 00:00:00

abstract：:A variety of methods have been used to attempt to decrease the allergenicity of food products, with highly variable success. Limited knowledge of allergen and epitope structures and the factors governing their stability may explain this, and the ensuing need for an empirical approach. A combined effort from a processi...

journal_title：Allergy

authors： Soler-Rivas C,Wichers HJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappaB (NF-kappaB) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappaB suppression in dendritic cells by adenoviral gene transfer of a novel mutated ...

journal_title：Allergy

authors： Zhou LF,Zhang MS,Hu AH,Zhu Z,Yin KS

更新日期：2008-05-01 00:00:00

abstract：:A simple microtiter assay for eosinophil activation is described. The assay used 1000-4000 eosinophils/microtiter well, and the design allows for a separate or simultaneous quantitative assessment of eosinophil adhesion to protein-coated microtiter wells and degranulation after stimulation with eosinophil-activating f...

journal_title：Allergy

authors： Reimert CM,Skov PS,Poulsen LK

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:The worldwide increasing incidence of allergic diseases requires the development of new, efficient vaccination strategies, the only curative treatment with a long-lasting effect. Current allergen-specific immunotherapy protocols suffer from limited efficacy and a long treatment time. METHODS:We engineered m...

journal_title：Allergy

authors： Crameri R,Flückiger S,Daigle I,Kündig T,Rhyner C

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Intradermal skin testing of the clinically important antibiotics ciprofloxacin, clarithromycin, and rifampicin in the case of suspected allergies to antibiotics is poorly standardized. For clinical practice, standardized procedures and protocols are desired. METHODS:Fifteen healthy volunteers were tested wi...

journal_title：Allergy

authors： Brož P,Harr T,Hecking C,Grize L,Scherer K,Jaeger KA,Bircher AJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：:The aim of the study was to develop and evaluate different methods of double-blind, placebo-controlled food challenge (DBPCFC) with apple. Three different DBPCFC models were evaluated: fresh apple juice, freshly grated apple, and freeze-dried apple powder. All challenges were performed outside the pollen season and to...

journal_title：Allergy

authors： Skamstrup Hansen K,Vestergaard H,Stahl Skov P,Søndergaard Khinchi M,Vieths S,Poulsen LK,Bindslev-Jensen C

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:CD40 and OX40 Ligand (OX40L) are cell-surface molecules expressed on airway smooth muscle (ASM) that can enhance inflammatory cell activation and survival. The aim of this study was to examine the effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on ASM CD40 and OX40L expres...

journal_title：Allergy

authors： Krimmer DI,Loseli M,Hughes JM,Oliver BG,Moir LM,Hunt NH,Black JL,Burgess JK

更新日期：2009-07-01 00:00:00

abstract：:The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line of defense. Apart from the well-described physical barrier and the mucociliary clearance, a variety of systems, including the airway microbiome, antimicrobial pr...

journal_title：Allergy

authors： Zhang N,Van Crombruggen K,Gevaert E,Bachert C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:A cross-sectional retrospective study suggested a link between allergic diseases and Parkinson's disease. However, the temporal association between asthma and Parkinson's disease remains unknown. METHODS:From the Taiwan National Health Insurance Research Database, 10 455 patients who were diagnosed with ast...

journal_title：Allergy

authors： Cheng CM,Wu YH,Tsai SJ,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Tsai CF,Yang AC,Lin WC,Pan TL,Chang WH,Chen TJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：:The aim of this systematic review was to summarize and assess the quality of asthma intervention health economic studies from 2002 to 2007, compare the study findings with clinical management guidelines, and suggest avenues for future improvement of asthma health economic studies. Forty of the 177 studies met our incl...

journal_title：Allergy

authors： Campbell JD,Spackman DE,Sullivan SD

更新日期：2008-12-01 00:00:00

abstract：:The yeast Pityrosporum orbiculare (P. orbiculare) is a member of the normal human cutaneous flora, but it is also associated with several clinical manifestations of the skin. We have previously observed IgE-binding components in P. orbiculare extracts, using sera from patients with atopic dermatitis. In the present st...

journal_title：Allergy

authors： Zargari A,Härfast B,Johansson S,Johansson SG,Scheynius A

更新日期：1994-01-01 00:00:00

abstract：:There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

journal_title：Allergy

authors： Panush RS,Veloso ML,Weiss S,Bielory L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Systemic allergic reactions are a risk for allergen immunotherapy that utilizes intact allergen preparations. We evaluated the safety, efficacy and immune mechanisms of short-course treatment with adjuvant-free Lolium perenne peptides (LPP) following a 6-week dose-escalation protocol. METHODS:In a prospecti...

journal_title：Allergy

authors： Mösges R,Koch AF,Raskopf E,Singh J,Shah-Hosseini K,Astvatsatourov A,Hauswald B,Yarin Y,Corazza F,Haazen L,Pirotton S,Allekotte S,Zadoyan G,Legon T,Durham SR,Shamji MH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Nasopharynx-associated lymphoid tissue (NALT) serves as an important inductive site for mucosal immunity in the upper respiratory tract. Despite its importance in the mucosal immune system, little is known regarding the role of NALT in airway allergic immune responses. We aimed to elucidate the role of NALT ...

journal_title：Allergy

authors： Kim DY,Fukuyama S,Nagatake T,Takamura K,Kong IG,Yokota Y,Lee CH,Kiyono H

更新日期：2012-04-01 00:00:00

abstract：:The aim of this study was to investigate possible effects of landscape design on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy from Uzbekistan where green areas have been changed during the last two decades by a State program. Sera from two different generations of Uzbek ...

journal_title：Allergy

authors： Garib V,Wollmann E,Djambekova G,Lemell P,Kmenta M,Berger U,Zieglmayer P,Valenta R

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the preventive potential ...

journal_title：Allergy

authors： Kratzer B,Köhler C,Hofer S,Smole U,Trapin D,Iturri J,Pum D,Kienzl P,Elbe-Bürger A,Gattinger P,Mittermann I,Linhart B,Gadermaier G,Jahn-Schmid B,Neunkirchner A,Valenta R,Pickl WF

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Chronic urticaria (CU) is a common skin disorder that causes a substantial burden on patients' quality-of-life (QoL). The aim of this work was to generate and validate a German version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q(2)oL) and to provide reference assessments of QoL. METHODS:The...

journal_title：Allergy

authors： Młynek A,Magerl M,Hanna M,Lhachimi S,Baiardini I,Canonica GW,Brzoza Z,Kasperska-Zajac A,Rogala B,Zalewska-Janowska A,Zuberbier T,Maurer M

更新日期：2009-06-01 00:00:00