Health economics of asthma: assessing the value of asthma interventions.

abstract：:In analogy with findings from animal experiments, people with low glutathione-peroxidase (GSH-Px) activity could be expected to have altered sensitivities to effects of drugs, chemicals and possibly food. We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance. Ten of...

journal_title：Allergy

authors： Malmgren R,Unge G,Zetterström O,Theorell H,de Wahl K

更新日期：1986-01-01 00:00:00

abstract：:The aim of the study was to develop and evaluate different methods of double-blind, placebo-controlled food challenge (DBPCFC) with apple. Three different DBPCFC models were evaluated: fresh apple juice, freshly grated apple, and freeze-dried apple powder. All challenges were performed outside the pollen season and to...

journal_title：Allergy

authors： Skamstrup Hansen K,Vestergaard H,Stahl Skov P,Søndergaard Khinchi M,Vieths S,Poulsen LK,Bindslev-Jensen C

更新日期：2001-02-01 00:00:00

abstract：:This study is an extended follow-up for 24 months of a 12-week trial to study the long-term clinical efficacy of low-dose inhaled budesonide (BUD) once or twice daily in children with mild asthma. A total of 122 children (mean age 9.7 years, girls/boys; 42/80) with mild asthma (FEV1 103.7% of predicted, reversibility ...

journal_title：Allergy

authors： Jónasson G,Carlsen KH,Jonasson C,Mowinckel P

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Immunoglobulin E (IgE)-mediated allergy belongs to common chronic disorders resulting from an interaction between both genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31.1, a region that is linked to asthma and ...

journal_title：Allergy

authors： Bucková D,Hollá LI,Schüller M,Znojil V,Vácha J

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Date-palm (Phoenix dactylifera L.) fruits are eaten daily by most inhabitants of the Middle East and the neighboring countries. Recent reports have indicated that dates are allergenic. This study aimed to investigate the antigenic and allergenic potential of date fruits. METHODS:Date-fruit extracts from eig...

journal_title：Allergy

authors： Kwaasi AA,Harfi HA,Parhar RS,Al-Sedairy ST,Collison KS,Panzani RC,Al-Mohanna FA

更新日期：1999-12-01 00:00:00

abstract：:Two methods of relating daily pollen counts to patients' symptom scores in clinical trials of hyposensitisation in hay fever are described. The problems involved in comparing results from different centres and years of a trial are discussed with particular reference to symptoms which are not pollen related. The Normal...

journal_title：Allergy

authors： Wilkinson P,Taudorf E

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Bakery workers may develop IgE-mediated allergy to liquid and aerosolized hen's egg proteins that are commonly used in the baking and confectionery industries. METHODS:We studied four bakery workers who had work-related allergic respiratory symptoms upon exposure to egg aerosols. The causative role of egg p...

journal_title：Allergy

authors： Escudero C,Quirce S,Fernández-Nieto M,Miguel J,Cuesta J,Sastre J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Mustard IgE-mediated allergy is supposed to be a rare cause of food allergy, and its clinical features and cross-reactivities have not been fully elucidated. METHODS:A prospective study was carried out, recruiting mustard allergic patients, and paired control subjects. A clinical questionnaire was administe...

journal_title：Allergy

authors： Figueroa J,Blanco C,Dumpiérrez AG,Almeida L,Ortega N,Castillo R,Navarro L,Pérez E,Gallego MD,Carrillo T

更新日期：2005-01-01 00:00:00

abstract：:Mast cell activation (MCA) occurs in a number of different clinical conditions, including IgE-dependent allergies, other inflammatory reactions, and mastocytosis. MCA-related symptoms may be mild, moderate, severe, or even life-threatening. The severity of MCA depends on a number of different factors, including geneti...

journal_title：Allergy

authors： Valent P

更新日期：2013-04-01 00:00:00

abstract：:Histamine is a key mediator in the development of allergy symptoms, and oral H(1)-antihistamines are among the most widely used treatments for symptomatic relief in conditions such as allergic rhinitis and chronic urticaria. Ebastine is a second-generation antihistamine which has been shown to be an effective treatmen...

journal_title：Allergy

authors： Sastre J

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

journal_title：Allergy

authors： Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Immune-modulation such as tolerance induction appears to be an upcoming concept to prevent development of atopic diseases. Pregnancy might present a critical period for preventing allergic sensitization of the progeny. We investigated the effect of maternal allergen exposures during pregnancy on allergen-ind...

journal_title：Allergy

authors： Gerhold K,Avagyan A,Reichert E,Seib C,Van DV,Luger EO,Hutloff A,Hamelmann E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The capacity of inflammatory cells to adhere involves an array of adhesion molecules, and is critical to the inflammatory responses seen in childhood asthma. We aimed to determine the changes of intercellular adhesion molecule-1 (ICAM-1) and L-selectin expressed on peripheral blood (PB) T lymphocytes and nat...

journal_title：Allergy

authors： Lin SJ,Chang LY,Yan DC,Huang YJ,Lin TJ,Lin TY

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Polcalcins are pollen-specific allergens with two EF-hand calcium-binding sites that exhibit strong cross-reactivity. Our objective was to isolate and express the cDNA coding of the EF-hand calcium-binding allergen from lilac pollen and to study cross-reactivity with other polcalcins from related and nonrela...

journal_title：Allergy

authors： Ledesma A,Barderas R,Westritschnig K,Quiralte J,Pascual CY,Valenta R,Villalba M,Rodríguez R

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Food allergy affects approximately 5% of children and is the leading cause of hospitalization for anaphylactic reactions in westernized countries. The mucosal adjuvant cholera toxin induces allergic sensitization to co-administered proteins in mice, while feeding the protein alone induces oral tolerance. Int...

journal_title：Allergy

authors： Bol-Schoenmakers M,Marcondes Rezende M,Bleumink R,Boon L,Man S,Hassing I,Fiechter D,Pieters RH,Smit JJ

更新日期：2011-03-01 00:00:00

abstract：:The hypothesis that increased reactivity to polymyxin B in asthmatic patients is not limited to the bronchi but also exists in basophils was investigated in 26 atopic asthmatic subjects. Quantification of basophil degranulation induced by polymyxin B was performed using a flow-cytometric method. Significant degranulat...

journal_title：Allergy

authors： Górski P,Rozniecki J,Kuźmińska B,Grzegorczyk J

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The function of skin mast cells has been well documented in IgE-mediated allergic reactions, whereas other mast cell functions are poorly defined. This study aimed at identifying novel mast cell proteins by proteome analysis of primary human skin mast cells. METHODS:The proteome of skin mast cells was compa...

journal_title：Allergy

authors： Gschwandtner M,Paulitschke V,Mildner M,Brunner PM,Hacker S,Eisenwort G,Sperr WR,Valent P,Gerner C,Tschachler E

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Histamine plays an important role in allergic inflammation. Histamine levels are regulated by histamine N-methyltransferase (HNMT). OBJECTIVE:To investigate the functional variability of HNMT gene in relation to genetic polymorphisms in patients with aspirin intolerant chronic urticaria (AICU). METHODS:Two...

journal_title：Allergy

authors： Kim SH,Kang YM,Kim SH,Cho BY,Ye YM,Hur GY,Park HS

更新日期：2009-02-01 00:00:00

abstract：:The efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double-blind, placebo-controlled trials (N = 1871) comparing the efficacy and safety of the SQ-standardized grass allergy immunotherapy...

journal_title：Allergy

authors： Nelson H,Blaiss M,Nolte H,Würtz SØ,Andersen JS,Durham SR

更新日期：2013-02-01 00:00:00

abstract：:The aim of the study was to investigate whether topical application of a beta-2-adrenostimulant (fenoterol) on the mucous membrane has a clinically significant anti-allergic effect. Thirty-three patients with grass pollen hay fever completed the trial which was a double-blind, placebo-controlled cross-over design. Aft...

journal_title：Allergy

authors： Borum P,Larsen FS

更新日期：1987-02-01 00:00:00

abstract：:Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-1 and IL-18, and is considered to be important for host defense against nematodes by inducing Th2 cytokine production via the IL-33 receptor. IL-33 receptor is a heterodimer of IL-1 receptor-like 1 (IL-1RL1; also called ST2, T1, Der4, an...

journal_title：Allergy

authors： Ohno T,Morita H,Arae K,Matsumoto K,Nakae S

更新日期：2012-10-01 00:00:00

abstract：:Two hundred and seventy patients with asthma and/or rhinitis (162 or 60% allergic, 108 or 40% non-allergic) were studied for sinus pathology by means of standard X-rays and tomograms. Sinus pathology was defined as abnormal sinus X-rays, either on standard or tomography. Fifty-four percent of the X-rays were classifie...

journal_title：Allergy

authors： De Cleyn KM,Kersschot EA,De Clerck LS,Ortmanns PM,De Schepper AM,Van Bever HP,Stevens WJ

更新日期：1986-07-01 00:00:00

abstract：:Subcellular sites of histamine in purified human lung mast cells and human peripheral blood basophils were determined using a newly developed enzyme-gold affinity method for ultrastructural analysis. The evolving morphologies of regulated secretion and recovery from regulated secretion in each cell showed that granule...

journal_title：Allergy

authors： Dvorak AM

更新日期：1997-01-01 00:00:00

abstract：:Several observations have indicated that house-dust mites (HDM) play an important role in allergic diseases. Thus, the primary form of treatment should aim at reducing exposure to HDM for these patients. Allergen-avoidance measures in homes have been demonstrated to be beneficial in decreasing the risk of sensitizatio...

journal_title：Allergy

authors： Kalpaklioğlu AF,Ferizli AG,Misirligil Z,Demirel YS,Gürbüz L

更新日期：1996-03-01 00:00:00

abstract：:IgG-binding to the surface of Langerhans cells (LC) is a feature of primary Sjögren's syndrome and might be associated with qualitative and quantitative defects in LC. Fifteen patients with primary Sjögren's syndrome and 15 healthy controls had a punch biopsy performed from clinically unaffected skin. LC were enumerat...

journal_title：Allergy

authors： Oxholm P,Oxholm A,Manthorpe R

更新日期：1986-08-01 00:00:00

abstract：:Chip pile workers are exposed to high concentrations of airborne mould spores. Few sporadic cases of allergic alveolitis have been reported in Finland. Eight non-smoking workers, six on chip piles and two on bark piles, were examined to study the immunological and clinical response to continuous mould spore exposure. ...

journal_title：Allergy

authors： Jäppinen P,Haahtela T,Liira J

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:The nasal allergen challenge (NAC) is a useful tool for the diagnosis of allergic rhinitis (AR) and local allergic rhinitis (LAR) and might serve to design and monitor allergen immunotherapy. Nevertheless, data about its safety and reproducibility are scarce. OBJECTIVE:To investigate the safety and reproduc...

journal_title：Allergy

authors： Eguiluz-Gracia I,Testera-Montes A,González M,Pérez-Sánchez N,Ariza A,Salas M,Moreno-Aguilar C,Campo P,Torres MJ,Rondon C

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The presence of anti-FcepsilonRI and anti-IgE autoantibodies in a subset of patients with chronic urticaria suggests their aetiopathogenetic role. In clinical practice, the presence of these antibodies is usually considered when the autologous serum skin test (ASST) is positive. AIMS:To evaluate if the posi...

journal_title：Allergy

authors： Fusari A,Colangelo C,Bonifazi F,Antonicelli L

更新日期：2005-02-01 00:00:00

abstract：:Screening of total IgE in 2814 cord blood samples was analysed by Phadebas IgE PRIST in 2 1-year birth cohorts (1983-1984 and 1985-1986) in Denmark (n = 1189 + 1625). 48.6% of the sera contained less IgE than the detection limit 0.1 kU/l. Cord blood IgE values greater than or equal to 0.5 kU/l were regarded as elevate...

journal_title：Allergy

authors： Hansen LG,Høst A,Halken S,Holmskov A,Husby S,Lassen LB,Storm K,Osterballe O

更新日期：1992-08-01 00:00:00

abstract：:Hypophysectomized (Hypo-X) rats did not develop contact dermatitis in response to dinitrochlorobenzene (DNCB). Syngeneic pituitary grafts placed under the kidney capsule or daily treatment with prolactin restored the DNCB-reactivity of Hypo-X animals. Combined treatment with other pituitary hormones was ineffective. T...

journal_title：Allergy

authors： Nagy E,Berczi I

更新日期：1981-08-01 00:00:00