Naturally occurring human IgA autoantibodies against IgE-DES myeloma protein. Prevalence and specificity.

abstract：BACKGROUND:Improving quality of life is considered to be a major endpoint and motivation for clinical intervention in patients with perennial allergic rhinitis (PAR). In addition to classical symptoms of congestion, pruritus, and rhinorrhea, patients will often complain of not being able to sleep well at night and of f...

journal_title：Allergy

authors： Hughes K,Glass C,Ripchinski M,Gurevich F,Weaver TE,Lehman E,Fisher LH,Craig TJ

更新日期：2003-05-01 00:00:00

abstract：:This is a description of the Study of Asthma, Genes and the Environment (SAGE), a novel birth cohort created from provincial healthcare administrative records. It is a general population-based cohort, composed of children at high and low risk for asthma, living in urban and rural environments in Manitoba, Canada. The ...

journal_title：Allergy

authors： Kozyrskyj AL,HayGlass KT,Sandford AJ,Paré PD,Chan-Yeung M,Becker AB

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Genomewide association studies (GWASs) of asthma have identified single-nucleotide polymorphisms (SNPs) that modestly increase the risk for asthma. This could be due to phenotypic heterogeneity of asthma. Bronchial hyperresponsiveness (BHR) is a phenotypic hallmark of asthma. We aim to identify susceptibilit...

journal_title：Allergy

authors： Nieuwenhuis MA,Siedlinski M,van den Berge M,Granell R,Li X,Niens M,van der Vlies P,Altmüller J,Nürnberg P,Kerkhof M,van Schayck OC,Riemersma RA,van der Molen T,de Monchy JG,Bossé Y,Sandford A,Bruijnzeel-Koomen CA,Gerth

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:This paper presents the response in subjects with asthma to gaseous air-pollution levels, weather, and medicine intake as identified by principal-component analysis and neural network techniques. Pulmonary function measured by respiratory peak-flow rate in nonallergic asthmatics was associated with ambient, low-level,...

journal_title：Allergy

authors： Moseholm L,Taudorf E,Frøsig A

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The precise immunological mechanisms for the early clinical protection of venom immunotherapy (VIT) have not yet been explained. Our aim was to evaluate whether high-affinity IgE receptor (FcεRI) and the related basophil function have a role in the induction of short-term VIT protection. METHODS:We included...

journal_title：Allergy

authors： Čelesnik N,Vesel T,Rijavec M,Šilar M,Eržen R,Košnik M,Kloft Žitnik SE,Avčin T,Korošec P

更新日期：2012-12-01 00:00:00

abstract：:In analogy with findings from animal experiments, people with low glutathione-peroxidase (GSH-Px) activity could be expected to have altered sensitivities to effects of drugs, chemicals and possibly food. We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance. Ten of...

journal_title：Allergy

authors： Malmgren R,Unge G,Zetterström O,Theorell H,de Wahl K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Modulation of leukocyte recruitment through blocking of chemokine receptors has been proposed as an attractive therapeutic strategy. We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensit...

journal_title：Allergy

authors： Gupta S,Erdmann G,Schulz-Maronde S,Escher SE,Richter R,Forssmann WG,Elsner J,Forssmann U

更新日期：2008-10-01 00:00:00

abstract：:A modified basophil degranulation test proved reliable and easily reproducible in the investigation of 50 patients with allergies to bee and/or wasp stings. Its diagnostic value is comparable to that of the RAST and it is, in addition, simpler, quicker and cheaper. Its disadvantage is that it has to be performed withi...

journal_title：Allergy

authors： Mumcuoglu Y,Wortmann F

更新日期：1980-06-01 00:00:00

abstract：:The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...

journal_title：Allergy

authors： Odelram H,Björkstén B,Chan SC,Hanifin JM,Kjellman NI

更新日期：1994-09-01 00:00:00

abstract：:Subcellular sites of histamine in purified human lung mast cells and human peripheral blood basophils were determined using a newly developed enzyme-gold affinity method for ultrastructural analysis. The evolving morphologies of regulated secretion and recovery from regulated secretion in each cell showed that granule...

journal_title：Allergy

authors： Dvorak AM

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Bronchial, nasal, and conjunctival challenges are useful for clarifying discordant clinical history (Hx) and skin and/or serologic tests and in assessing semiquantitative changes in biologic sensitivity over time. The objective of this study was to determine the safety and reproducibility of repeated latex-a...

journal_title：Allergy

authors： Kurtz KM,Hamilton RG,Schaefer JA,Primeau MN,Adkinson NF Jr

更新日期：2001-09-01 00:00:00

abstract：:A variety of methods have been used to attempt to decrease the allergenicity of food products, with highly variable success. Limited knowledge of allergen and epitope structures and the factors governing their stability may explain this, and the ensuing need for an empirical approach. A combined effort from a processi...

journal_title：Allergy

authors： Soler-Rivas C,Wichers HJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In atopic individuals, exposure to allergens is followed by recruitment of blood eosinophils in the target tissue. We investigated whether allergen inhalation challenge could result in depletion of blood eosinophils overexpressing adhesion molecules involved in eosinophil migration. METHODS:Blood eosinophil...

journal_title：Allergy

authors： Lantero S,Spallarossa D,Silvestri M,Sabatini F,Scarso L,Crimi E,Rossi GA

更新日期：2002-11-01 00:00:00

abstract：:We performed immunoblotting experiments to determine specific IgE and IgG subclass responses to Candida albicans antigens in allergic bronchopulmonary aspergillosis (ABPA) patients. This is a first report describing C. albicans antigens recognized by serum IgE and IgG subclasses of ABPA patients sensitized to that yea...

journal_title：Allergy

authors： Roig E,Malo JL,Montplaisir S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total serum IgE l...

journal_title：Allergy

authors： Tewfik MA,Bossé Y,Lemire M,Hudson TJ,Vallée-Smejda S,Al-Shemari H,Laprise C,Desrosiers M

更新日期：2009-05-01 00:00:00

abstract：:This study investigated the relationship between the specific immunoglobulin E (IgE) profile for 40 allergens using a novel microarray technique (BioIC) and fraction of exhaled nitric oxide (FeNO) in a population sample of 1321 children. Significant positive associations were found between FeNO and sensitization to mi...

journal_title：Allergy

authors： Yao TC,Tsai HJ,Tu YL,Chang SW,Hua MC,Liao SL,Tsai MH,Chiu CY,Lai SH,Yeh KW,Huang JL,PATCH study group.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：:Busereline acetate is an LH-RH agonist that was found to induce local reactions at the injection site or generalized minor skin reactions in some patients. Since these reactions may represent the first reaction of systemic anaphylaxis, we tested the non-specific histamine releasing activity of this drug by intradermal...

journal_title：Allergy

authors： Bousquet J,Hédon B,Hejjaoui A,Chanal I,Michel FB

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Patients with nonallergic asthma frequently show autoreactivity as do subjects with chronic urticaria (CU). Activation of the coagulation cascade and hyper-expression of vascular endothelial growth factor (VEGF) were recently found in CU, and there is sparse evidence that the same may occur in asthma. OBJEC...

journal_title：Allergy

authors： Asero R,Tedeschi A,Cugno M

更新日期：2011-10-01 00:00:00

abstract：:The prevalence of allergic rhinitis (AR) has witnessed a progressive increase in China. A survey of self-reported AR using validated questionnaire-based telephone interviews in adult subjects conducted between 2004 and 2005 demonstrated that the prevalence of AR in 11 major cities across China was 11.1%1 . A subsequen...

journal_title：Allergy

authors： Xian M,Zhang L

更新日期：2020-08-02 00:00:00

abstract：BACKGROUND:With the current increasing incidence of allergies worldwide, new treatments showing efficacy and long term safety are needed for chronic conditions such as persistent allergic rhinitis (PER). New generation H1-antihistamines have demonstrated anti-allergic properties, which could possibly enhance their effe...

journal_title：Allergy

authors： Fantin S,Maspero J,Bisbal C,Agache I,Donado E,Borja J,Mola O,Izquierdo I,international Rupatadine study group.

更新日期：2008-07-01 00:00:00

abstract：:There are several reasons for considering the hypothesis that food hypersensitivity might relate to rheumatic diseases. Food can evoke immune responses. Food can cause immunologically mediated symptoms. Immunological mechanisms are important in the pathogenesis of rheumatic diseases. Antigens triggering rheumatic resp...

journal_title：Allergy

authors： Panush RS,Veloso ML,Weiss S,Bielory L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Asthma is a complex disorder, which is known to be affected by interactions between genetic and environmental factors. The human Eotaxin 1 and CCR3 attract eosinophils and Th2-lymphocytes to migrate to the inflammatory foci that could represent a key mechanism in allergy and asthma. OBJECTIVE:We hypothesize...

journal_title：Allergy

authors： Wang TN,Chiang W,Tseng HI,Chu YT,Chen WY,Shih NH,Ko YC

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Levels of n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs in breast milk are associated with the development of allergic diseases up to school age. However, it is unknown whether this relationship persists when the child becomes older. We therefore studied the association between levels of n-3 PUFAs an...

journal_title：Allergy

authors： van Elten TM,van Rossem L,Wijga AH,Brunekreef B,de Jongste JC,Koppelman GH,Smit HA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the ocular surface disease in atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC) has not been fully understood. We tried to clarify the differences in the ocular surface status in patients with AKC, VKC, and healthy control subjects. METHODS:Twenty-four eyes of 12 AK...

journal_title：Allergy

authors： Hu Y,Matsumoto Y,Dogru M,Okada N,Igarashi A,Fukagawa K,Tsubota K,Fujishima H

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Immunotherapy with Hymenoptera venoms is highly effective but causes allergic side-effects frequently, especially when honeybee venom is used. Therefore, our objective was to investigate the effect of pretreatment with the antihistamine fexofenadine on the incidence of allergic side-effects during ultrarush ...

journal_title：Allergy

authors： Reimers A,Hari Y,Müller U

更新日期：2000-05-01 00:00:00

abstract：:A two-site immunometric assay based on monoclonal antibodies (mAb) was developed for the measurement of a 20-kDa major allergen of cow. The sensitivity of this assay was (BDA20) 1 ng/ml. It was used to measure airborne allergen concentrations in 10 Finnish cowsheds. The mean concentration of the BDA20 measured at two ...

journal_title：Allergy

authors： Ylönen J,Virtanen T,Rytkönen M,Mäntyjärvi R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) epidemiology has been largely studied using symptom-based case definitions, without assessment of objective sinus findings. OBJECTIVE:To describe radiologic sinus opacification and the prevalence of CRS, defined by the co-occurrence of symptoms and sinus opacification, in a gene...

journal_title：Allergy

authors： Hirsch AG,Nordberg C,Bandeen-Roche K,Tan BK,Schleimer RP,Kern RC,Sundaresan A,Pinto JM,Kennedy TL,Greene JS,Kuiper JR,Schwartz BS

更新日期：2020-04-01 00:00:00