Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice.

abstract：:In 77 consecutive patients with grass pollen rhinitis as the only allergic disease, treatment with sodium cromoglycate (SCG) nasal spray, hyposensitization with aluminium hydroxide adsorbed extract of grass pollen as perennial treatment, and a combination of the two was compared. Specific serum-IgE, IgG and IgG4 were ...

journal_title：Allergy

authors： Andersen NH,Jeppesen F,Schiøler T,Osterballe O

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...

journal_title：Allergy

authors： Krause K,Spohr A,Zuberbier T,Church MK,Maurer M

更新日期：2013-07-01 00:00:00

abstract：:A young woman (26 years old), with gastrointestinal candidosis of 8 months duration, was hospitalized in our department to study her cell immunity. Five minutes after an id injection of PHA (bactophytohaemoagglutinin M, Difco, 1 mg), mix monilieae, mix tricophyton and PPD Berna, she showed an extensive wheal and flare...

journal_title：Allergy

authors： Schiavino D,Nucera E,Murzilli F,Schinco G,Papa G,Fais G,Patriarca G

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:As in vitro diagnosis of wasp venom sensitization by specific serum IgE has a sensitivity of only 60-80%, additional in vitro tests are desirable. Basophil activation is associated with the expression of CD63 and its measurement has been proposed as a novel in vitro test for immediate-type allergy. Furthermo...

journal_title：Allergy

authors： Erdmann SM,Sachs B,Kwiecien R,Moll-Slodowy S,Sauer I,Merk HF

更新日期：2004-10-01 00:00:00

abstract：:Overproduction of periostin, an IL-13-inducible matricellular protein, despite corticosteroid treatment is thought to be involved in the chronicity of allergic inflammation seen in corticosteroid-refractory tissue fibrosis. Therefore, we hypothesized that some tissue cells must produce periostin in a corticosteroid-in...

journal_title：Allergy

authors： Shoda T,Futamura K,Kobayashi F,Saito H,Matsumoto K,Matsuda A

更新日期：2013-11-01 00:00:00

abstract：:The nasal mucociliary clearance is an important defense mechanism of the upper respiratory tract. It is known to be influenced by many pharmacologic substances. We investigated the effects of three topical intranasal antiallergic formulations containing disodium cromoglycate (DNCG), dimethindene maleate (DMM), and aze...

journal_title：Allergy

authors： Alberty J,Stoll W

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Variable airflow obstruction and airway hyperresponsiveness (AHR) are features of asthma, which are absent in nonasthmatic eosinophilic bronchitis (EB). Airway remodelling is characteristic of both conditions suggesting that remodelling and airway dysfunction are disassociated, but whether the airway geometr...

journal_title：Allergy

authors： Siddiqui S,Gupta S,Cruse G,Haldar P,Entwisle J,Mcdonald S,Whithers PJ,Hainsworth SV,Coxson HO,Brightling C

更新日期：2009-06-01 00:00:00

abstract：:The increase in prevalence and burden of atopic diseases, i.e. eczema, rhinitis, and asthma over the past decades was paralleled by a worldwide increase in attention-deficit/hyperactivity disorder (ADHD) diagnoses. We systematically reviewed epidemiologic studies investigating the relationship between atopic diseases ...

journal_title：Allergy

authors： Schmitt J,Buske-Kirschbaum A,Roessner V

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Since 1988, numerous allergen immunotherapy guidelines (AIT-GLs) have been developed by national and international organizations to guide physicians in AIT. Even so, AIT is still severely underused. OBJECTIVE:To evaluate AIT-GLs with AGREE-II, developed in 2010 by McMaster University methodologists to compr...

journal_title：Allergy

authors： Larenas-Linnemann DES,Antolín-Amérigo D,Parisi C,Nakonechna A,Luna-Pech JA,Wedi B,Davila I,Gómez M,Levin M,Ortega Martell JA,Klimek L,Rosario N,Muraro AM,Agache I,Bousquet J,Sheikh A,EAACI International Societies Council.

更新日期：2018-03-01 00:00:00

abstract：:We examined the effects of glucocorticosteroids (GCS) on antigen-induced bronchial anaphylactic reactions (BAR) in SD rats immunized with ovalbumin (OA) and alum. The animals were treated with vehicle, budesonide (BUD), dexamethasone (DEX), or hydrocortisone (HC) at various times before intravenous (i.v.) antigen chal...

journal_title：Allergy

authors： Dahlbäck M,Bergstrand H,Brattsand R

更新日期：1986-04-01 00:00:00

abstract：:It is well established that different sites in healthy human skin are colonized by distinct microbial communities due to different physiological conditions. However, few studies have explored microbial heterogeneity between skin sites in diseased skin, such as atopic dermatitis (AD) lesions. To address this issue, we ...

journal_title：Allergy

authors： Ottman N,Barrientos-Somarribas M,Fyhrquist N,Alexander H,Wisgrill L,Olah P,Tsoka S,Greco D,Levi-Schaffer F,Soumelis V,Schröder JM,Kere J,Nestle FO,Barker J,Ranki A,Lauerma A,Homey B,Andersson B,Alenius H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The mechanisms driving glucocorticoid (GC) insensitivity in patients with severe asthma are still unknown. Recent evidence suggests the existence of GC-insensitive pathways in airway smooth muscle (ASM) caused by a defect in GC receptor (GRα) function. We examined whether other mechanisms could potentially e...

journal_title：Allergy

authors： Chachi L,Abbasian M,Gavrila A,Alzahrani A,Tliba O,Bradding P,Wardlaw AJ,Brightling C,Amrani Y

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:New therapies are necessary to address inadequate asthma control in many patients. This study sets out to investigate whether hypoxia-inducible factor (HIF) is essential for development of allergic airway inflammation (AAI) and therefore a potential novel target for asthma treatment. METHODS:Mice conditiona...

journal_title：Allergy

authors： Huerta-Yepez S,Baay-Guzman GJ,Bebenek IG,Hernandez-Pando R,Vega MI,Chi L,Riedl M,Diaz-Sanchez D,Kleerup E,Tashkin DP,Gonzalez FJ,Bonavida B,Zeidler M,Hankinson O

更新日期：2011-07-01 00:00:00

abstract：:Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma. PubMed, Embase ...

journal_title：Allergy

authors： Agache I,Beltran J,Akdis C,Akdis M,Canelo-Aybar C,Canonica GW,Casale T,Chivato T,Corren J,Del Giacco S,Eiwegger T,Firinu D,Gern JE,Hamelmann E,Hanania N,Mäkelä M,Hernández-Martín I,Nair P,O'Mahony L,Papadopoulos NG

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The house dust mite (HDM) Dermatophagoides pteronyssinus is a major allergen source eliciting allergic asthma. The aim of the study was to identify new important HDM allergens associated with allergic asthma. METHODS:A cDNA coding for a new mite allergen, designated Der p 21, was isolated using immunoglobul...

journal_title：Allergy

authors： Weghofer M,Dall'Antonia Y,Grote M,Stöcklinger A,Kneidinger M,Balic N,Krauth MT,Fernández-Caldas E,Thomas WR,van Hage M,Vieths S,Spitzauer S,Horak F,Svergun DI,Konarev PV,Valent P,Thalhamer J,Keller W,Valenta R,Vrtal

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:The cellular immunity to Yersinia enterocolitica serotype 3 and crude human thyroid extract in 64 patients with thyroid diseases and 25 controls was studied by the leucocyte migration test. In the patient group as a whole and in patients with Graves' disease and nontoxic diffuse goitre a significantly reduced leucocyt...

journal_title：Allergy

authors： Bech K,Clemmensen O,Larsen JH,Thyme S,Bendixen G

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Asthma and obesity are chronic multifactorial conditions that are associated with gene-environment interaction and immune function. Although the data are not fully consistent, it seems that obesity increases the risk of asthma and compromises asthma control. OBJECTIVE:To investigate the impact that weight c...

journal_title：Allergy

authors： Moreira A,Bonini M,Garcia-Larsen V,Bonini S,Del Giacco SR,Agache I,Fonseca J,Papadopoulos NG,Carlsen KH,Delgado L,Haahtela T

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Specific IgE tests are sometimes difficult to interpret due to structural similarities between certain food and pollen allergens. This may be the reason why concomitant sensitization to peanut and birch pollen is frequently seen. The aim of this study was to investigate reported symptoms to peanut- and birch...

journal_title：Allergy

authors： Asarnoj A,Ostblom E,Ahlstedt S,Hedlin G,Lilja G,van Hage M,Wickman M

更新日期：2010-02-01 00:00:00

abstract：:The prevalence of chronic immune and metabolic disorders is increasing rapidly. In particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive pulmonary disease have become major healthcare and economic burdens worldwide. Recent advances in microbiome research have led to significant dis...

journal_title：Allergy

authors： Alemao CA,Budden KF,Gomez HM,Rehman SF,Marshall JE,Shukla SD,Donovan C,Forster SC,Yang IA,Keely S,Mann ER,El Omar EM,Belz GT,Hansbro PM

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:The precise immunological mechanisms for the early clinical protection of venom immunotherapy (VIT) have not yet been explained. Our aim was to evaluate whether high-affinity IgE receptor (FcεRI) and the related basophil function have a role in the induction of short-term VIT protection. METHODS:We included...

journal_title：Allergy

authors： Čelesnik N,Vesel T,Rijavec M,Šilar M,Eržen R,Košnik M,Kloft Žitnik SE,Avčin T,Korošec P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Alkaline serine proteases from six prevalent airborne Penicillium and Aspergillus species have been identified as a group of major allergens (group 13). After entering human airways, the allergens are in initial contacts with respiratory epithelial cells. The purpose of this study is to investigate interacti...

journal_title：Allergy

authors： Tai HY,Tam MF,Chou H,Peng HJ,Su SN,Perng DW,Shen HD

更新日期：2006-03-01 00:00:00

abstract：:Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-1 and IL-18, and is considered to be important for host defense against nematodes by inducing Th2 cytokine production via the IL-33 receptor. IL-33 receptor is a heterodimer of IL-1 receptor-like 1 (IL-1RL1; also called ST2, T1, Der4, an...

journal_title：Allergy

authors： Ohno T,Morita H,Arae K,Matsumoto K,Nakae S

更新日期：2012-10-01 00:00:00

abstract：:Ispaghula powder, which is used as a component in bulk laxatives, is known to induce allergic reactions when inhaled by occupationally exposed persons. We have tested whether nurses sensitized by inhalation could get allergic symptoms when challenged by eating ispaghula. Of six nurses tested, all developed symptoms fr...

journal_title：Allergy

authors： Machado L,Stålenheim G

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) may affect the expression of hundreds of genes in different cells and tissues from patients with intermittent allergic rhinitis (IAR). It is a formidable challenge to understand these complex changes by studying individual genes. In this study, we aimed to identify (i) pathways affected...

journal_title：Allergy

authors： Wang H,Chavali S,Mobini R,Muraro A,Barbon F,Boldrin D,Aberg N,Benson M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Food allergy may present with a plethora of gastrointestinal and extraintestinal symptoms such as abdominal pain, diarrhea, cardiocirculatory symptoms, cutaneous reactions, or rhinitis. Macropathological lesions like lymphofollicular hyperplasia and erosive or ulcerative lesions have seldom been described in...

journal_title：Allergy

authors： Hagel AF,de Rossi TM,Zopf Y,Lindner AS,Dauth W,Neurath MF,Raithel M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Budesonide/formoterol (Symbicort) Maintenance and Reliever Therapy (SMART) is an effective asthma-management approach that treats symptoms with rapid increases in budesonide/formoterol. The cost-effectiveness of SMART vs higher fixed-dose budesonide/formoterol or salmeterol/fluticasone is unknown. METHODS:T...

journal_title：Allergy

authors： Price D,Wirén A,Kuna P

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Reasons for asthma hospitalizations are dynamic and complex. Comorbid conditions are important contributors to most chronic diseases today. We aim to characterize and describe risk factors associated with hospitalizations due to asthma in the Languedoc-Roussillon region (France) in 2009. METHODS:Programme d...

journal_title：Allergy

authors： Aubas C,Bourdin A,Aubas P,Gamez AS,Halimi L,Vachier I,Malafaye N,Chanez P,Molinari N

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The beta-lactam allergic work-up is mostly standardized. However, the negative predictive value of drug provocation tests is not yet well established. METHOD:A historical-prospective multicentre cohort study was conducted in four centres (one in France, one in Portugal, two in Italy) to assess the negative ...

journal_title：Allergy

authors： Demoly P,Romano A,Botelho C,Bousquet-Rouanet L,Gaeta F,Silva R,Rumi G,Rodrigues Cernadas J,Bousquet PJ

更新日期：2010-03-01 00:00:00

abstract：:Thirty children with rhinoconjunctivitis due to birch pollinosis were treated in a double blind manner for 10 months with enteric-coated capsules containing either a birch pollen preparation (n = 14) with doses up to 1.4 X 10(6) biologic units per day or placebo (n = 16). Compared with the placebo group the actively t...

journal_title：Allergy

authors： Möller C,Dreborg S,Lanner A,Björkstén B

更新日期：1986-05-01 00:00:00