Abstract:
BACKGROUND:Food allergy may present with a plethora of gastrointestinal and extraintestinal symptoms such as abdominal pain, diarrhea, cardiocirculatory symptoms, cutaneous reactions, or rhinitis. Macropathological lesions like lymphofollicular hyperplasia and erosive or ulcerative lesions have seldom been described in gastroscopy and colonoscopy previously. METHODS:Fifteen patients presenting with unspecific abdominal symptoms in which food allergy was detected in due course were included. During the examination process, those patients showed various indications for small-bowel capsule endoscopy, such as weight loss and anemia. RESULTS:Fourteen (93.3%) of the 15 small-bowel capsule endoscopies could be assessed, showing nonerosive lesions such as erythema, swelling, and lymphoid hyperplasia in 8 patients (57.1%) and erosive lesions such as aphthoid lesions, erosions, and petechiae in 4 patients (28.6%) with food allergy. CONCLUSION:In 15 patients with confirmed food allergy and after exclusion of other diseases, 12 (85.7%) showed various unspecific nonerosive or erosive mucosal lesions within the small bowel, resulting, however, partially in grave consequences such as anemia. Lymphoid hyperplasia was the most prominent finding in 7 patients (50%), albeit infectious disease had been excluded. Anemia improved within 1 year after adequate antiallergic treatment.
journal_name
Allergyjournal_title
Allergyauthors
Hagel AF,de Rossi TM,Zopf Y,Lindner AS,Dauth W,Neurath MF,Raithel Mdoi
10.1111/j.1398-9995.2011.02738.xsubject
Has Abstractpub_date
2012-02-01 00:00:00pages
286-92issue
2eissn
0105-4538issn
1398-9995journal_volume
67pub_type
杂志文章,随机对照试验相关文献
ALLERGY文献大全abstract::This is the first report on inhalative and ingestive allergy to the common edible mushroom Boletus edulis (Be) (English, edible boletus; German, Steinpilz; French, bolet; Italian, porcino or boleto) belonging to the class Basidiomycetes. Four cases observed in our allergy unit are presented, showing different clinical...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1997.tb01232.x
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:The presence of anti-FcepsilonRI and anti-IgE autoantibodies in a subset of patients with chronic urticaria suggests their aetiopathogenetic role. In clinical practice, the presence of these antibodies is usually considered when the autologous serum skin test (ASST) is positive. AIMS:To evaluate if the posi...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2005.00673.x
更新日期:2005-02-01 00:00:00
abstract::Leukotrienes are a recently discovered group of arachidonic acid-derived lipid mediators. Using radioimmunoassay and high pressure liquid chromatography (HPLC), we have identified the SRS-A sulphidopeptide leukotrienes (LTC4, LTD4 and LTE4) in nasal washings from patients with allergic rhinitis who underwent nasal cha...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1985.tb04147.x
更新日期:1985-01-01 00:00:00
abstract::We observed two cases of maculopapular eruption occurring 12-72 h after the administration of aminocaproic acid (ACA). Patch tests performed with ACA were positive. Clinical and allergologic patterns suggest the type IV mechanism of hypersensitivity. We present what we believe are the first two cases described of hype...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1995.tb01217.x
更新日期:1995-09-01 00:00:00
abstract::Inhalation and nasal aspirin challenge has been investigated in asthma patients with co-existing rhinitis. Eight of 39 asthma patients were diagnosed as aspirin-sensitive on the basis of inhalation challenge. Seven aspirin-sensitive asthmatics were subjected to nasal aspirin provocation. During nasal challenge, all se...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1991.tb04218.x
更新日期:1991-08-01 00:00:00
abstract::A variety of methods have been used to attempt to decrease the allergenicity of food products, with highly variable success. Limited knowledge of allergen and epitope structures and the factors governing their stability may explain this, and the ensuing need for an empirical approach. A combined effort from a processi...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2001.00917.x
更新日期:2001-01-01 00:00:00
abstract::In recent years, patients allergic to amoxicillin (AX) but with good tolerance of penicillin G (PG) have been described. It has been suggested that the epitope implicated in this type of sensitization might be located on the side-chain of the AX molecule. Thus, cross-reactivity between AX and cephadroxil (CEPH), a cep...
journal_title:Allergy
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::The bronchial epithelium acts as a physical barrier to the ingress of airborne irritants and plays an active role in the airways immune response, reacting to a range of environmental stimuli to enable interaction with immune and inflammatory cells. It is well established that mucosal damage and epithelial cell sheddin...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:
更新日期:1999-08-01 00:00:00
abstract::Various biological assays are used for qualitative and quantitative measurements of interleukin 1 (IL-1) in supernatants from cell cultures. The purpose of the present study was to compare the specificity and variability of three cellular IL-1 bioassays: the PHA co-stimulatory human T lymphocyte proliferation assay, t...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1991.tb00544.x
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has been identified as the major birch pollen allergen. However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 and other components of the birch pollen extract, remain incompletely understoo...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.13948
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Reasons for asthma hospitalizations are dynamic and complex. Comorbid conditions are important contributors to most chronic diseases today. We aim to characterize and describe risk factors associated with hospitalizations due to asthma in the Languedoc-Roussillon region (France) in 2009. METHODS:Programme d...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.12137
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Allergic asthma is usually considered to be provoked by aeroallergens. However, we have recently recognized a group of children with food allergies who also develop asthma when exposed to the aerosolized form of the food. METHODS:Between 1997 and 1999 we prospectively identified children with an immunoglobu...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1034/j.1398-9995.2002.03366.x
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:There is theoretical evidence that specific airway conductance (SGaw) could be more reliable than forced expiratory volume in 1 s (FEV1) for assessing changes in airway calibre. We investigated the changes in FEV1 and SGaw when assessing bronchial responses to occupational agents. METHODS:SGaw and FEV1 were...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1046/j.1398-9995.2003.00313.x
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies about the effects of glucocorticoid on ILC2s in asthma patients. Our objective was to perform a perspective study and evaluate the ILC2 activity after glucocorticoid therapy in asthma patient...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.13438
更新日期:2018-09-01 00:00:00
abstract::The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1994.tb00141.x
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Subjective symptoms after food challenges are difficult to interpret and no standard is available. We discuss a strategy for how to interpret a diary. Furthermore, the interobserver reliability is evaluated. METHODS:Diaries for 32 patients with subjective symptoms were used. The diaries were re-evaluated wi...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2003.00437.x
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire. METHODS:To validate questions used in a country-wide study among university students aged 18-25 year...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1034/j.1398-9995.2001.056005377.x
更新日期:2001-05-01 00:00:00
abstract::Basophils are evolutionarily conserved in many animal species, in spite of the fact that they account for <1% of peripheral blood leukocyte. This suggests that basophils have an indispensable and nonredundant role in vivo, even though they show some phenotypic similarity with tissue-resident mast cells. However, their...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2011.02613.x
更新日期:2011-09-01 00:00:00
abstract::Although H1 antihistamine compounds (H1) are highly effective in the treatment of allergic rhinitis (AR), their role in the treatment of asthma is still controversial. Because a strong association between AR and bronchial hyperresponsiveness (BHR) has been reported, this study was designed to assess the effect of a ne...
journal_title:Allergy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1398-9995.2001.00629.x
更新日期:2001-01-01 00:00:00
abstract::Sublingual immunotherapy has been shown in some clinical studies to modulate allergen-specific antibody responses [with a decrease in the immunoglobulin E/immunoglobulin G4 (IgE/IgG4) ratio] and to reduce the recruitment and activation of proinflammatory cells in target mucosa. Whereas a central paradigm for successfu...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2006.01002.x
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Nasal congestion is the predominant symptom in perennial allergic rhinitis (PAR), and it seems to be mainly related to the late-phase inflammatory events. The present pilot study aimed to evaluate the therapeutic effect exerted by fexofenadine in patients with PAR due to mite allergy. METHODS:This study was...
journal_title:Allergy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1398-9995.2001.00191.x
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Retrospective studies provide evidence that rhinitis is associated with more severe asthma. The aim of this study was to evaluate prospectively whether rhinitis is a predictor of increased asthma severity. METHODS:Five hundred and fifty-seven patients with severe asthma were enrolled. During 1 year of follo...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2007.01624.x
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Clinical tools for predicting poor outcomes in asthma patients are lacking. This study investigated the association of asthma control and subsequent severe asthma-related healthcare events in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. METHODS:The extent of...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2007.01383.x
更新日期:2007-06-01 00:00:00
abstract::Effects of a thromboxane synthetase inhibitor (OKY-046) and a cyclooxygenase inhibitor (indomethacin) on bronchial hyperresponsiveness induced by subthreshold concentration of aerosolized thromboxane A2 analogue (STA2) were investigated in anesthetized, artificially ventilated guinea pigs in order to examine the role ...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1992.tb00961.x
更新日期:1992-04-01 00:00:00
abstract::An egg protein, lysozyme, is a still unlabeled additive currently used in cheese preparation. Furthermore, the WHO-FAO committee considers it innocuous. However, 31% of children and 8% of adults with food allergies are allergic to eggs. This work aimed to determine the percentage of patients sensitized to lysozyme fro...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1997.tb00980.x
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:The world's most catastrophic and deadly thunderstorm asthma epidemic struck Melbourne, Australia, on November 21, 2016. OBJECTIVE:Among thunderstorm-affected patients presenting to emergency rooms (ERs), we investigated risk factors predicting severe attacks requiring admission to hospital. METHODS:Thunde...
journal_title:Allergy
pub_type: 杂志文章,多中心研究
doi:10.1111/all.13609
更新日期:2019-01-01 00:00:00
abstract:RATIONALE:The European Position Paper on Sinusitis (EPOS) guidelines provide composite criteria to evaluate chronic rhinosinusitis (CRS) control, taking into consideration the severity of patients' symptoms, aspect of nasal mucosa and medical intake as parameters of CRS control. OBJECTIVES:To study the degree of CRS c...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.12983
更新日期:2017-02-01 00:00:00
abstract::The relation between platelet counts (PCT) and IgE was studied in cord blood from 136 European newborns. PCT was significantly lower (P = 0.0014) when cord-IgE was superior to 1.20 IU/ml (n = 29; 245,000/microliter) than when it was inferior to this value (n = 107; 284,080/microliter) which resulted in a significant n...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1989.tb02237.x
更新日期:1989-02-01 00:00:00
abstract::Using monoclonal anti-human IgE antibodies recognizing the D epsilon 1 or D epsilon 2 epitope, we have developed a sandwich radioimmunoassay (RIA) to determine IgE in human cell cultures. With the help of this assay, various methods of measuring an actual de novo IgE synthesis were compared. It was necessary to subtra...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1986.tb00327.x
更新日期:1986-08-01 00:00:00
abstract::Sera from 425 patients were analysed with Phadebas RAST reagents against a panel of 19 allergens and the most commonly positive results were to grass pollen, Dermatophagoides pteronyssinus and cat epithelium. Of the 275 sera RAST-positive to any allergen, 261 were positive by a RAST technique which used a mixture of t...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1980.tb01796.x
更新日期:1980-09-01 00:00:00