Screening for IgE-mediated allergy.

abstract：BACKGROUND:Fluorescence-labeled MHC class II/peptide tetramer complexes are considered as optimal tools to characterize allergen-specific CD4(+) T cells, but this technique is restricted to frequently expressed HLA class II molecules and knowledge of immunodominant epitopes. In contrast, allergen-stimulated proliferati...

journal_title：Allergy

authors： Van Hemelen D,Mahler V,Fischer G,Fae I,Reichl-Leb V,Pickl W,Jutel M,Smolinska S,Ebner C,Bohle B,Jahn-Schmid B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Despite considerable efforts to develop anti dust mite strategies, surprisingly few studies have evaluated the allergen content in different types of mattresses in everyday use. This study investigated the presence of mite feces (an indicator of mite allergens) in foam and spring mattresses. METHODS:The hom...

journal_title：Allergy

authors： Schei MA,Hessen JO,Lund E

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) may affect the expression of hundreds of genes in different cells and tissues from patients with intermittent allergic rhinitis (IAR). It is a formidable challenge to understand these complex changes by studying individual genes. In this study, we aimed to identify (i) pathways affected...

journal_title：Allergy

authors： Wang H,Chavali S,Mobini R,Muraro A,Barbon F,Boldrin D,Aberg N,Benson M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Spanish population is rather homogeneous in its genetic and sociocultural characteristics, but allergen sensitization shows wide geographical variations. We aimed at assessing whether sensitization to different allergens in the diverse geographical areas induced different clinical and quality-of-life charact...

journal_title：Allergy

authors： Valero A,Quirce S,Dávila I,Delgado J,Domínguez-Ortega J

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Health-related quality of Life in patients with chronic urticaria is evaluated by mean of generic instruments or questionnaire designed for skin diseases. No disease-specific tool is now available for the assessment of chronic urticaria impact from patients' viewpoint. OBJECTIVE:The aim of our study is to d...

journal_title：Allergy

authors： Baiardini I,Pasquali M,Braido F,Fumagalli F,Guerra L,Compalati E,Braga M,Lombardi C,Fassio O,Canonica GW

更新日期：2005-08-01 00:00:00

abstract：:The association between food allergy and celiac disease (CD) is still to be clarified. We screened for CD 319 patients with severe food allergy (IgE > 85 kU/l against food proteins and a history of severe allergic reactions) who underwent specific food oral immunotherapy (OIT), together with 128 children with mild all...

journal_title：Allergy

authors： Pillon R,Ziberna F,Badina L,Ventura A,Longo G,Quaglia S,De Leo L,Vatta S,Martelossi S,Patano G,Not T,Berti I

更新日期：2015-10-01 00:00:00

abstract：:The leading priority for the Polish Presidency of the Council of the European Union was to reduce health inequalities across European societies, and, within its framework, prevention and control of respiratory diseases in children. This very important paper contain proposal of international cooperation on the preventi...

journal_title：Allergy

authors： Samoliński B,Fronczak A,Kuna P,Akdis CA,Anto JM,Bialoszewski AZ,Burney PG,Bush A,Czupryniak A,Dahl R,Flood B,Galea G,Jutel M,Kowalski ML,Palkonen S,Papadopoulos N,Raciborski F,Sienkiewicz D,Tomaszewska A,Von Mutius

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Several studies showed that calcium-binding proteins have a fixed place in the spectrum of allergenic substances. Often the binding of a calcium ion induces conformational changes and affects immunoglobulin E-binding to the allergen. Hence, the quantitative characterization of the binding to calcium is of im...

journal_title：Allergy

authors： Hebenstreit D,Ferreira F

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Differential leukocyte counts are of proven clinical value, but information about basophil counts in normal and disease conditions is scarce although basophils are regarded as key effector cells in allergy. AIMS:To establish and validate flowcytometric methods for counting basophils in peripheral human bloo...

journal_title：Allergy

authors： Ducrest S,Meier F,Tschopp C,Pavlovic R,Dahinden CA

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Date-palm (Phoenix dactylifera L.) fruits are eaten daily by most inhabitants of the Middle East and the neighboring countries. Recent reports have indicated that dates are allergenic. This study aimed to investigate the antigenic and allergenic potential of date fruits. METHODS:Date-fruit extracts from eig...

journal_title：Allergy

authors： Kwaasi AA,Harfi HA,Parhar RS,Al-Sedairy ST,Collison KS,Panzani RC,Al-Mohanna FA

更新日期：1999-12-01 00:00:00

abstract：:House-dust mites are a major source of allergens. Beds are often heavily infested. It is conceivable that, during the winter period in temperate climates, the ambient indoor air is too dry for their survival, but that mites can still survive in beds where the humidity is raised when the bed is occupied. To investigate...

journal_title：Allergy

authors： de Boer R,Kuller K

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Food atopy patch tests (APTs) are considered a useful tool for the diagnosis of food allergy. Hypersensitivity to peanuts has not been investigated by means of APTs so far. METHODS:APTs and skin prick tests (SPTs) with peanuts were performed in 136 atopic dermatitis (AD) patients. Relevance of positive and ...

journal_title：Allergy

authors： Seidenari S,Giusti F,Bertoni L,Mantovani L

更新日期：2003-06-01 00:00:00

abstract：:Effects of a thromboxane synthetase inhibitor (OKY-046) and a cyclooxygenase inhibitor (indomethacin) on bronchial hyperresponsiveness induced by subthreshold concentration of aerosolized thromboxane A2 analogue (STA2) were investigated in anesthetized, artificially ventilated guinea pigs in order to examine the role ...

journal_title：Allergy

authors： Saito M,Fujimura M,Sakamoto S,Miyake Y,Shintani H,Yasui M,Matsuda T

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause. Indeed, recent evidence indicates that bacteria-derived extracellular vesicles (EV) appear to be an important causative agent of inflammatory diseases. Here, we ...

journal_title：Allergy

authors： Choi EB,Hong SW,Kim DK,Jeon SG,Kim KR,Cho SH,Gho YS,Jee YK,Kim YK

更新日期：2014-04-01 00:00:00

abstract：:Atopic dermatitis (AD) is a common inflammatory skin condition that has traditionally been considered a paradigmatic type 2 immunity (T2)-driven disease. Interleukin (IL)-4 and IL-13 are both pivotal cytokines involved in the generation of allergic diseases. Currently, besides dupilumab, which blocks the binding of bo...

journal_title：Allergy

authors： Bieber T

更新日期：2020-01-01 00:00:00

abstract：:Dialysed extracts of alder (Alnus glutinosa) and hazel (Corylus avellana) pollens were characterized by immunochemical methods. The alder pollen extract contained at least 33 distinct antigens of which one, antigen 5, was classified as a major allergen, three, antigens 4, 10, and 17, were classified as intermediate al...

journal_title：Allergy

authors： Ipsen H,Bøwadt H,Janniche H,Nüchel Petersen B,Munch EP,Wihl JA,Løwenstein H

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:  Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP). However, the mechanism of inflammation in CRS has still not been fully elucidated. The aim of the s...

journal_title：Allergy

authors： Keswani A,Chustz RT,Suh L,Carter R,Peters AT,Tan BK,Chandra R,Kim SH,Azam T,Dinarello CA,Kern RC,Schleimer RP,Kato A

更新日期：2012-01-01 00:00:00

abstract：:Fourteen adults and 10 children with active atopic dermatitis entered this double blind cross-over study of oral disodium cromoglycate (DSCG) (adults 200 mg qid, children 100 mg qid) compared with placebo. Oral DSCG and placebo were given for 6 weeks in random order. According to the investigators' assessments of ecze...

journal_title：Allergy

authors： Lindskov R,Knudsen L

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:We report on a 37-year-old man without history of previous allergic disease who developed an aseptic intolerance reaction to a chromium-cobalt alloy, with local discomfort, loosening, and absence of fracture healing. Both in vivo and in vitro allergoimmunologic diagnostic tests were performed. METHODS:Patch...

journal_title：Allergy

authors： Thomas P,Summer B,Sander CA,Przybilla B,Thomas M,Naumann T

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the preventive potential ...

journal_title：Allergy

authors： Kratzer B,Köhler C,Hofer S,Smole U,Trapin D,Iturri J,Pum D,Kienzl P,Elbe-Bürger A,Gattinger P,Mittermann I,Linhart B,Gadermaier G,Jahn-Schmid B,Neunkirchner A,Valenta R,Pickl WF

更新日期：2019-02-01 00:00:00

abstract：:Pityrosporum orbiculare and Candida albicans extracts were separated by SDS-PAGE, and IgE binding was detected by immunoblotting with 21 patient sera that were RAST positive to both yeasts. Cross-wise inhibition was performed of IgE binding of a serum pool containing IgE antibodies to both yeasts. The pool was mixed w...

journal_title：Allergy

authors： Huang X,Johansson SG,Zargari A,Nordvall SL

更新日期：1995-08-01 00:00:00

abstract：:The eosinophilic granulocyte is commonly associated with allergic inflammation. Although blood eosinophilia frequently accompanies atopic dermatitis, accumulation of tissue eosinophils is not prominent. Recent studies have elucidated the structure, content, and activities of the eosinophil. In addition, immunofluoresc...

journal_title：Allergy

authors： Leiferman KM

更新日期：1989-01-01 00:00:00

abstract：:The phenotypes and receptors of the intraepithelial lymphocytes which are a major component of the mucosal immune system are of considerable interest. Intraepithelial lymphocytes, especially those of the intestines, are well documented. The nasal intraepithelial lymphocytes probably play a key role in the immune defen...

journal_title：Allergy

authors： Pawankar R,Okuda M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Clinical tools for predicting poor outcomes in asthma patients are lacking. This study investigated the association of asthma control and subsequent severe asthma-related healthcare events in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. METHODS:The extent of...

journal_title：Allergy

authors： Sullivan SD,Wenzel SE,Bresnahan BW,Zheng B,Lee JH,Pritchard M,Kamath TV,Weiss ST,TENOR Study Group.

更新日期：2007-06-01 00:00:00

abstract：:The background of this study is the finding of several studies that the frequency of respiratory allergies was significantly higher in the former West Germany than the former East Germany. The present study investigated the levels of allergens of house-dust mite (Der p 1 and Der f 1), cat (Fel d 1), and cockroach (Bla...

journal_title：Allergy

authors： Fahlbusch B,Heinrich J,Gross I,Jäger L,Richter K,Wichmann HE

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:New therapies are necessary to address inadequate asthma control in many patients. This study sets out to investigate whether hypoxia-inducible factor (HIF) is essential for development of allergic airway inflammation (AAI) and therefore a potential novel target for asthma treatment. METHODS:Mice conditiona...

journal_title：Allergy

authors： Huerta-Yepez S,Baay-Guzman GJ,Bebenek IG,Hernandez-Pando R,Vega MI,Chi L,Riedl M,Diaz-Sanchez D,Kleerup E,Tashkin DP,Gonzalez FJ,Bonavida B,Zeidler M,Hankinson O

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Vernal keratoconjunctivitis (VKC) is a severe ocular allergy with pathogenic mechanism poorly understood and no efficacious treatment. The aims of the study were to determine quantities and distribution of Hsp chaperones in the conjunctiva of VKC patients and assess their levels in conjunctival epithelial an...

journal_title：Allergy

authors： Leonardi A,Tarricone E,Corrao S,Alaibac M,Corso AJ,Zavan B,Venier P,Conway de Macario E,Macario AJ,Di Stefano A,Cappello F,Brun P

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:In sublingual immunotherapy, optimal doses are a key factor for therapeutic outcomes. The aim of this study with tablets containing carbamylated monomeric house dust mite allergoids was to determine the most effective and safe dose. METHODS:In this double-blind, placebo-controlled dose-finding study, 131 pa...

journal_title：Allergy

authors： Hüser C,Dieterich P,Singh J,Shah-Hosseini K,Allekotte S,Lehmacher W,Compalati E,Mösges R

更新日期：2017-01-01 00:00:00