CB2 receptors regulate natural killer cells that limit allergic airway inflammation in a murine model of asthma.

abstract：:We performed immunoblotting experiments to determine specific IgE and IgG subclass responses to Candida albicans antigens in allergic bronchopulmonary aspergillosis (ABPA) patients. This is a first report describing C. albicans antigens recognized by serum IgE and IgG subclasses of ABPA patients sensitized to that yea...

journal_title：Allergy

authors： Roig E,Malo JL,Montplaisir S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Histamine intolerance is thought to trigger manifold clinical symptoms after ingesting histamine-rich food due to reduced activity of diamine oxidase (DAO). No study has hitherto systematically assessed daily fluctuations of histamine levels and DAO activities in symptomatic patients. The aim of the study wa...

journal_title：Allergy

authors： Pinzer TC,Tietz E,Waldmann E,Schink M,Neurath MF,Zopf Y

更新日期：2018-04-01 00:00:00

abstract：:Micro-organisms constantly invade the human body and may form a threat to our health. Traditionally, concepts of defence mechanisms have included a protective outer layer of epithelia and a vigilant immune system searching for areas where the integrity of the outer layer may be compromised. Instead of considering thes...

journal_title：Allergy

authors： van Tongeren J,Reinartz SM,Fokkens WJ,de Jong EC,van Drunen CM

更新日期：2008-09-01 00:00:00

abstract：:A young woman (26 years old), with gastrointestinal candidosis of 8 months duration, was hospitalized in our department to study her cell immunity. Five minutes after an id injection of PHA (bactophytohaemoagglutinin M, Difco, 1 mg), mix monilieae, mix tricophyton and PPD Berna, she showed an extensive wheal and flare...

journal_title：Allergy

authors： Schiavino D,Nucera E,Murzilli F,Schinco G,Papa G,Fais G,Patriarca G

更新日期：1992-04-01 00:00:00

abstract：:A common feature of environmental irritants is their ability to cause local inflammation which could alter airway function. The principal targets of such injury are the epithelial cells lining the airway passages and the lower respiratory gas-exchange areas. While host atopy is a recognized risk factor for airway infl...

journal_title：Allergy

authors： Spiteri MA,Bianco A,Strange RC,Fryer AA

更新日期：2000-01-01 00:00:00

abstract：:The relation between platelet counts (PCT) and IgE was studied in cord blood from 136 European newborns. PCT was significantly lower (P = 0.0014) when cord-IgE was superior to 1.20 IU/ml (n = 29; 245,000/microliter) than when it was inferior to this value (n = 107; 284,080/microliter) which resulted in a significant n...

journal_title：Allergy

authors： Magnusson CG,de Weck AL

更新日期：1989-02-01 00:00:00

abstract：:A simple microtiter assay for eosinophil activation is described. The assay used 1000-4000 eosinophils/microtiter well, and the design allows for a separate or simultaneous quantitative assessment of eosinophil adhesion to protein-coated microtiter wells and degranulation after stimulation with eosinophil-activating f...

journal_title：Allergy

authors： Reimert CM,Skov PS,Poulsen LK

更新日期：1998-02-01 00:00:00

abstract：:The aim of biological standardization (BS) is to equilibrate the activity (potency) of allergen extracts from different source materials. This was done by performing skin prick tests (SPT) on patients who were sensitive to one of the following 10 allergens: Birch, alder, hazel, timothy, rye grass, velvet grass, cultiv...

journal_title：Allergy

authors： Dreborg S,Belin L,Eriksson NE,Grimmer O,Kunkel G,Malling HJ,Nilsson G,Sjögren I,Zetterström O

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The nasal allergen challenge (NAC) is a useful tool for the diagnosis of allergic rhinitis (AR) and local allergic rhinitis (LAR) and might serve to design and monitor allergen immunotherapy. Nevertheless, data about its safety and reproducibility are scarce. OBJECTIVE:To investigate the safety and reproduc...

journal_title：Allergy

authors： Eguiluz-Gracia I,Testera-Montes A,González M,Pérez-Sánchez N,Ariza A,Salas M,Moreno-Aguilar C,Campo P,Torres MJ,Rondon C

更新日期：2019-06-01 00:00:00

abstract：:Pharmacologic intervention in the management of allergic conjunctivitis was evaluated with different topical ocular agents in man. Their effect can be precisely assessed with the conjunctival provocation test (CPT). A potent specific H1-receptor antagonist, 0.05% mequitazine eye-drops, was tested in a double-blind ran...

journal_title：Allergy

authors： Persi L,Dupin O,Arnaud B,Trinquand C,Michel FB,Bousquet J

更新日期：1997-04-01 00:00:00

abstract：:The levels of peripheral-blood, naturally occurring aliphatic polyamines, such as putrescine, spermidine, and spermine, from 21 bronchial asthmatic patients (11 atopics and 10 nonatopics) were measured by postcolumn derivatization high-performance liquid chromatography analysis. None of the patients, except the 44-yea...

journal_title：Allergy

authors： Kurosawa M,Shimizu Y,Tsukagoshi H,Ueki M

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total serum IgE l...

journal_title：Allergy

authors： Tewfik MA,Bossé Y,Lemire M,Hudson TJ,Vallée-Smejda S,Al-Shemari H,Laprise C,Desrosiers M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

journal_title：Allergy

authors： Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The house dust mite (HDM) Dermatophagoides pteronyssinus is a major allergen source eliciting allergic asthma. The aim of the study was to identify new important HDM allergens associated with allergic asthma. METHODS:A cDNA coding for a new mite allergen, designated Der p 21, was isolated using immunoglobul...

journal_title：Allergy

authors： Weghofer M,Dall'Antonia Y,Grote M,Stöcklinger A,Kneidinger M,Balic N,Krauth MT,Fernández-Caldas E,Thomas WR,van Hage M,Vieths S,Spitzauer S,Horak F,Svergun DI,Konarev PV,Valent P,Thalhamer J,Keller W,Valenta R,Vrtal

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Venom immunotherapy (VIT) is regarded as an established and efficient treatment of Hymenoptera venom allergy. Different frequencies of side-effects have been reported in the literature, depending on the hyposensitization regimen (conventional outpatient programme, rush immunotherapy, ultra rush immunotherapy...

journal_title：Allergy

authors： Wenzel J,Meissner-Kraemer M,Bauer R,Bieber T,Gerdsen R

更新日期：2003-11-01 00:00:00

abstract：:The prevalence and specificity of naturally occurring human IgA anti-IgE autoantibodies (a-E Ab) were studied by ELISA with anti-IgA monoclonal antibodies (mAb) and a purified myeloma IgE as solid-phase protein, i.e., IgE-DES(kappa). Such detected IgA a-E Ab were common among adults, and significantly increased geomet...

journal_title：Allergy

authors： Magnusson CG

更新日期：1994-12-01 00:00:00

abstract：:Formoterol, a new beta 2-selective long-acting bronchodilator, was compared with terbutaline in terms of ability to inhibit dual phase skin reactions to anti-human IgE in volunteers. Anti-IgE induced an early wheal and flare reaction (WFR) followed by a progressively increasing induration, the late phase reaction (LCR...

journal_title：Allergy

authors： Grönneberg R,Zetterström O

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Recurrent angioedema (RecA) is a frequent clinical problem characterized by suddenly occurring cutaneous and/or mucosal swellings. Depending on their location, RecA may be painful, hindering, disfiguring, or even life-threatening. The assessment of disease activity in affected patients is important to guide ...

journal_title：Allergy

authors： Weller K,Groffik A,Magerl M,Tohme N,Martus P,Krause K,Metz M,Staubach P,Maurer M

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Dupilumab, a fully human monoclonal antibody that binds IL-4Rα and inhibits signaling of both IL-4 and IL-13, has shown efficacy across multiple diseases with underlying type 2 signatures and is approved for treatment of asthma, atopic dermatitis, and chronic sinusitis with nasal polyposis. We sought to prov...

journal_title：Allergy

authors： Le Floc'h A,Allinne J,Nagashima K,Scott G,Birchard D,Asrat S,Bai Y,Lim WK,Martin J,Huang T,Potocky TB,Kim JH,Rafique A,Papadopoulos NJ,Stahl N,Yancopoulos GD,Murphy AJ,Sleeman MA,Orengo JM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Staphylococcus aureus (S. aureus) is frequently detected in the skin of patients with atopic dermatitis (AD), and involved in the flare of AD. There are some evidence-specific strains of S. aureus affect the severity of AD. However, the mechanism of predominant colonization and the aggravation of dermatitis ...

journal_title：Allergy

authors： Moriwaki M,Iwamoto K,Niitsu Y,Matsushima A,Yanase Y,Hisatsune J,Sugai M,Hide M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Nasopharynx-associated lymphoid tissue (NALT) serves as an important inductive site for mucosal immunity in the upper respiratory tract. Despite its importance in the mucosal immune system, little is known regarding the role of NALT in airway allergic immune responses. We aimed to elucidate the role of NALT ...

journal_title：Allergy

authors： Kim DY,Fukuyama S,Nagatake T,Takamura K,Kong IG,Yokota Y,Lee CH,Kiyono H

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:In high-risk populations, allergen-specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the preventive potential ...

journal_title：Allergy

authors： Kratzer B,Köhler C,Hofer S,Smole U,Trapin D,Iturri J,Pum D,Kienzl P,Elbe-Bürger A,Gattinger P,Mittermann I,Linhart B,Gadermaier G,Jahn-Schmid B,Neunkirchner A,Valenta R,Pickl WF

更新日期：2019-02-01 00:00:00

abstract：:Because humans breathe through the nose, the nasal mucosa becomes sensitized to inhalant allergens. Allergic rhinitis is, together with allergic conjunctivitis, the best example of a type I hypersensitivity reaction. It is an inflammation of the nasal mucosa induced by specific immune recognition of exogenous allergen...

journal_title：Allergy

authors： Van Cauwenberge PB

更新日期：1997-01-01 00:00:00

abstract：:We describe eight patients suffering from Mercurochrome allergy. Patch and prick tests were carried out with the following organic and inorganic mercury compounds: thimerosal, Mercurochrome, phenylmercuric acetate, phenylmercuric nitrate, metallic mercury, and mercuric chloride, and with sodium fluorescein. Two patien...

journal_title：Allergy

authors： Galindo PA,Feo F,García R,Gómez E,Borja J,Fernández F

更新日期：1997-11-01 00:00:00

abstract：:PVG rats given injections of 1 microgram ovalbumin (OA) together with 10 mg Silica gel failed to provide serosal mast cells or lung tissue with the capacity to release histamine on in vitro challenge with the antigen. However, if such animals were injected i.p. with 100 mg of alum (without any further antigen addition...

journal_title：Allergy

authors： Bergstrand H,Andersson I,Nyström I,Pauwels R,Bazin H

更新日期：1983-05-01 00:00:00

abstract：:Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the approach to patients with allergic diseases encompasses novel developments in the area of personalized medicine, disease phenotyping and endotyping, and the develo...

journal_title：Allergy

authors： Breiteneder H,Peng YQ,Agache I,Diamant Z,Eiwegger T,Fokkens WJ,Traidl-Hoffmann C,Nadeau K,O'Hehir RE,O'Mahony L,Pfaar O,Torres MJ,Wang DY,Zhang L,Akdis CA

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:Bronchial asthma is common in Kuwait, a desert country, but the sensitizing allergens are uncertain. This study investigated the sensitizing allergens in Kuwaiti patients with extrinsic asthma. METHODS:A total of 553 asthmatics (male:female ratio: 1.4; mean age: 31.7 years [range 3-76 years]) and 112 matche...

journal_title：Allergy

authors： Ezeamuzie CI,Thomson MS,Al-Ali S,Dowaisan A,Khan M,Hijazi Z

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：:In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...

journal_title：Allergy

authors： Dorsch W,Ring J

更新日期：1984-01-01 00:00:00