Profilin is a marker of severity in allergic respiratory diseases.

abstract：:Although mediators, such as lipids, cytokines, and chemokines, are related to the appearance of an IPR, there has been no reliable indicator to predict conditions for the appearance of an IPR. In this study, we adopted a proteomic approach to investigate the pathogenesis at the level of the plasma proteins and to deve...

journal_title：Allergy

authors： Rhim T,Choi YS,Nam BY,Uh ST,Park JS,Kim YH,Paik YK,Park CS

更新日期：2009-01-01 00:00:00

abstract：:In recent years, significant attention has been paid to the use of biotechnology to improve the quality and quantity of the food supply due in part to the projected growth in the world population, plus limited options available for increasing the amount of land under cultivation. Alterations in the food supply induced...

journal_title：Allergy

authors： Lehrer SB,Bannon GA

更新日期：2005-05-01 00:00:00

abstract：:A group of nine patients with respiratory symptoms after nonspecific irritating stimuli, but without any IgE-mediated allergy or demonstrable bronchial obstruction, were referred to the asthma/allergy outpatient department for evaluation of suspected asthma. In order to find a provocation model and objectively assess ...

journal_title：Allergy

authors： Millqvist E,Löwhagen O

更新日期：1996-06-01 00:00:00

abstract：:The red cell-linked antigen-antiglobulin reaction (RCLAAR) with stearoyldextran-coated erythrocytes was used to characterize the immunoglobulin (Ig) classes and IgG subclasses of dextran reactive antibodies (DRA) in 27 dextran reactors (DR) and 96 on reactors (DNR). High titres of dextran reactive IgG were regularly f...

journal_title：Allergy

authors： Kraft D,Hedin H,Richter W,Scheiner O,Rumpold H,Devey ME

更新日期：1982-10-01 00:00:00

abstract：:To determine optimal conditions for allergen preservation, we investigated the influence of different stabilizing additives and of storage temperature on the allergen activity of apple protein preparations, obtained by extraction in phosphate buffer or by precipitation in diacetone alcohol and resolubilization in phos...

journal_title：Allergy

authors： Rudeschko O,Fahlbusch B,Henzgen M,Schlenvoigt G,Herrmann D,Vieths S,Jäger L

更新日期：1995-07-01 00:00:00

abstract：:It was the aim of the study to compare the efficacy and side effects of oral antihistamine and nasal glucocorticoid therapy in seasonal allergic, rhinitis. In a double blind, double-dummy, group-comparative study, 61 adult grass pollen allergic patients were either treated with dexchlorpheniramine maleate sustained re...

journal_title：Allergy

authors： Munch EP,Søborg M,Nørreslet TT,Mygind N

更新日期：1983-10-01 00:00:00

abstract：:The diagnosis of food IgE-dependent hypersensitivity is based on the demonstration of specific IgE, completed by provocation tests. Two immunoenzymatic techniques, the Phadezym and the FAST, are compared with the Phadebas RAST, in 86 sera (23 controls, 28 from patients with a reported food allergy and 35 with a positi...

journal_title：Allergy

authors： Moneret-Vautrin DA,Gueant JL,Abdel-Ghani A,Maria Y,Nicolas JP

更新日期：1990-02-01 00:00:00

abstract：:The prevalence of allergic rhinitis (AR) has witnessed a progressive increase in China. A survey of self-reported AR using validated questionnaire-based telephone interviews in adult subjects conducted between 2004 and 2005 demonstrated that the prevalence of AR in 11 major cities across China was 11.1%1 . A subsequen...

journal_title：Allergy

authors： Xian M,Zhang L

更新日期：2020-08-02 00:00:00

abstract：BACKGROUND:The complex pathogenesis of atopic dermatitis (AD) is guided by cell surface receptor-mediated signal transduction regulated in lipid rafts. Miltefosine is a raft-modulating molecule targeting cell membranes. With this controlled clinical study, the clinical and immunomodulatory efficacy of miltefosine was i...

journal_title：Allergy

authors： Dölle S,Hoser D,Rasche C,Loddenkemper C,Maurer M,Zuberbier T,Worm M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a chronic airway inflammatory disease involving the complementary actions of innate and adaptive immune responses. Endogenously generated cannabinoids acting via CB2 receptors play important roles in both homeostatic and inflammatory processes. However, the contribution of CB2-acting eicos...

journal_title：Allergy

authors： Ferrini ME,Hong S,Stierle A,Stierle D,Stella N,Roberts K,Jaffar Z

更新日期：2017-06-01 00:00:00

abstract：:Species of the Cupressaceae family are a worldwide cause of respiratory allergies. We used monoclonal antibodies (mAbs) to investigate the presence and the nature of cross-reacting epitopes shared by various components within Cupressus arizonica pollen extract (CaE) or by CaE and pollen extract from C. sempervirens (C...

journal_title：Allergy

authors： Barletta B,Tinghino R,Corinti S,Afferni C,Iacovacci P,Mari A,Pini C,Di Felice G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Efficacy testing of immunotherapy in field studies is often hampered by variation of airborne allergens. Standardized allergen exposure in challenge chamber settings might be an alternative. Therefore, we developed a universal technique to create an atmosphere loaded with allergen particles of adjustable siz...

journal_title：Allergy

authors： Lueer K,Biller H,Casper A,Windt H,Mueller M,Badorrek P,Haefner D,Framke T,Koch A,Ziehr H,Krug N,Koch W,Hohlfeld JM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies about the effects of glucocorticoid on ILC2s in asthma patients. Our objective was to perform a perspective study and evaluate the ILC2 activity after glucocorticoid therapy in asthma patient...

journal_title：Allergy

authors： Yu QN,Guo YB,Li X,Li CL,Tan WP,Fan XL,Qin ZL,Chen D,Wen WP,Zheng SG,Fu QL

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Rhinitis symptoms and IgE-sensitization often mismatch. Asymptomatic sensitization is an established risk factor for later rhinitis, whereas it is not clear whether rhinitis is a risk factor for later development of IgE-sensitization. OBJECTIVE:To investigate whether nonallergic rhinitis is a risk factor fo...

journal_title：Allergy

authors： Bodtger U,Poulsen LK,Linneberg A

更新日期：2006-06-01 00:00:00

abstract：:This is a description of the Study of Asthma, Genes and the Environment (SAGE), a novel birth cohort created from provincial healthcare administrative records. It is a general population-based cohort, composed of children at high and low risk for asthma, living in urban and rural environments in Manitoba, Canada. The ...

journal_title：Allergy

authors： Kozyrskyj AL,HayGlass KT,Sandford AJ,Paré PD,Chan-Yeung M,Becker AB

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Bronchial, nasal, and conjunctival challenges are useful for clarifying discordant clinical history (Hx) and skin and/or serologic tests and in assessing semiquantitative changes in biologic sensitivity over time. The objective of this study was to determine the safety and reproducibility of repeated latex-a...

journal_title：Allergy

authors： Kurtz KM,Hamilton RG,Schaefer JA,Primeau MN,Adkinson NF Jr

更新日期：2001-09-01 00:00:00

abstract：:The aim of the study was to investigate whether topical application of a beta-2-adrenostimulant (fenoterol) on the mucous membrane has a clinically significant anti-allergic effect. Thirty-three patients with grass pollen hay fever completed the trial which was a double-blind, placebo-controlled cross-over design. Aft...

journal_title：Allergy

authors： Borum P,Larsen FS

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Endothelial (EMPs) and platelet microparticles (PMPs) have been studied as biomarkers in several inflammatory diseases and as central players in intercellular communication. METHODS:In this cross-sectional study, we aimed to assess microparticle levels in asthma. Circulating microparticles and inflammatory ...

journal_title：Allergy

authors： Duarte D,Taveira-Gomes T,Sokhatska O,Palmares C,Costa R,Negrão R,Guimarães JT,Delgado L,Soares R,Moreira A

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Mast cells have recently been shown to control neutrophil recruitment during T-cell mediated cutaneous DTH reaction in vivo through TNF-alpha and MIP-2, the functional murine analogue of human IL-8. Although the nature of signals transmitted from T cells which activate mast cells has not yet been defined, we...

journal_title：Allergy

authors： Salamon P,Shoham NG,Gavrieli R,Wolach B,Mekori YA

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. Studies with pollen allergen immunotherapy are limited to observational studies. The aim of this study was to evaluate the clinical efficacy and safety of Phleum pratense subcutaneous imm...

journal_title：Allergy

authors： Rondón C,Blanca-López N,Campo P,Mayorga C,Jurado-Escobar R,Torres MJ,Canto G,Blanca M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:New therapies are necessary to address inadequate asthma control in many patients. This study sets out to investigate whether hypoxia-inducible factor (HIF) is essential for development of allergic airway inflammation (AAI) and therefore a potential novel target for asthma treatment. METHODS:Mice conditiona...

journal_title：Allergy

authors： Huerta-Yepez S,Baay-Guzman GJ,Bebenek IG,Hernandez-Pando R,Vega MI,Chi L,Riedl M,Diaz-Sanchez D,Kleerup E,Tashkin DP,Gonzalez FJ,Bonavida B,Zeidler M,Hankinson O

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Type-I-allergy to natural rubber latex (NRL) has been shown to be more prevalent among certain groups of patients. Children suffering from chronic renal failure (CRF) could be a suspected risk group because of their intense exposure to latex through catheters, gloves and anesthetic equipment during frequent ...

journal_title：Allergy

authors： Dehlink E,Prandstetter C,Eiwegger T,Putschögl B,Urbanek R,Szépfalusi Z

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：:Ketotifen is marketed throughout the world as an antiallergy drug, but whether it affects infiltration of inflammatory cells into airway mucosa is not known. We studied the effects of ketotifen on symptoms, pulmonary function, and airway inflammation in 25 patients with atopic asthma. Patients took ketotifen (1 mg twi...

journal_title：Allergy

authors： Hoshino M,Nakamura Y,Shin Z,Fukushima Y

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Information about the influence of housing and occupant characteristics on mite allergen concentrations is crucial to determine which methods could be used to decrease exposure of susceptible subjects. OBJECTIVES:To identify housing and occupant characteristics that are associated with mite allergen concent...

journal_title：Allergy

authors： van Strien RT,Gehring U,Belanger K,Triche E,Gent J,Bracken MB,Leaderer BP

更新日期：2004-06-01 00:00:00

abstract：:The role of cytokines in the accumulation of eosinophil granulocytes in inflamed tissue has been studied extensively during recent years, and these molecules have been found to participate throughout the whole process of eosinophil recruitment. Haematopoietic cytokines such as IL-3, IL-5 and GM-CSF stimulate the proli...

journal_title：Allergy

authors： Lampinen M,Carlson M,Håkansson LD,Venge P

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:IgG to galactose-α-1,3-galactose (α-gal) are highly abundant natural antibodies (Ab) in humans. α-Gal-specific IgE Ab cause a special form of meat allergy characterized by severe systemic reactions 3-7 h after consumption of red meat. We investigated 20 patients who experienced such reactions and characteriz...

journal_title：Allergy

authors： Kollmann D,Nagl B,Ebner C,Emminger W,Wöhrl S,Kitzmüller C,Vrtala S,Mangold A,Ankersmit HJ,Bohle B

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Undernotification is well recognized as a key challenge to the study of anaphylaxis mortality, but it is seldom mentioned that one of its reasons is the difficult coding of the condition under the tenth revision of the international classification of diseases (ICD-10), given that there are no anaphylaxis-spe...

journal_title：Allergy

authors： Tanno LK,Ganem F,Demoly P,Toscano CM,Bierrenbach AL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Characterization of uncontrolled asthma burden in a natural treatment setting can influence treatment recommendations and clinical practice. The objective was to characterize and compare the economic burden of severe or difficult-to-treat asthma in uncontrolled and controlled patients. METHODS:Baseline pati...

journal_title：Allergy

authors： Sullivan SD,Rasouliyan L,Russo PA,Kamath T,Chipps BE,TENOR Study Group.

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:As in vitro diagnosis of wasp venom sensitization by specific serum IgE has a sensitivity of only 60-80%, additional in vitro tests are desirable. Basophil activation is associated with the expression of CD63 and its measurement has been proposed as a novel in vitro test for immediate-type allergy. Furthermo...

journal_title：Allergy

authors： Erdmann SM,Sachs B,Kwiecien R,Moll-Slodowy S,Sauer I,Merk HF

更新日期：2004-10-01 00:00:00