Plasma protein profiles in early asthmatic responses to inhalation allergen challenge.

abstract：BACKGROUND:Dissecting complex diseases in underlying distinct traits and studying these for their genetic basis might enhance the power as well as the specificity, of detection of disease genes. These phenotypes are known as intermediate phenotypes. OBJECTIVE:We were interested in the atopic basis of asthma, and used ...

journal_title：Allergy

authors： Kurz T,Altmueller J,Strauch K,Rüschendorf F,Heinzmann A,Moffatt MF,Cookson WO,Inacio F,Nürnberg P,Stassen HH,Deichmann KA

更新日期：2005-02-01 00:00:00

abstract：:This guideline is the result of a consensus reached during a panel discussion at the 2nd International Consensus Meeting on Urticaria, Urticaria 2004, a joint initiative of the European Academy of Allergology and Clinical Immunology Dermatology Section and the European Union (EU)-funded network of excellence, GA2LEN. ...

journal_title：Allergy

authors： Zuberbier T,Bindslev-Jensen C,Canonica W,Grattan CE,Greaves MW,Henz BM,Kapp A,Kozel MM,Maurer M,Merk HF,Schäfer T,Simon D,Vena GA,Wedi B,EAACI\/GA2LEN\/EDF.

更新日期：2006-03-01 00:00:00

abstract：:Inhaled corticosteroids are recommended as first-line therapy in patients with moderate to severe asthma. The use of these agents in the milder form of asthma is controversial because of their potential adverse effects, especially in growing children. We investigated 49 asthmatic children (38 treated with beclomethaso...

journal_title：Allergy

authors： Martinati LC,Bertoldo F,Gasperi E,Fortunati P,Lo Cascio V,Boner AL

更新日期：1998-07-01 00:00:00

abstract：:Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H(1)-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only mediator involved in the inflammatory cascade. Th...

journal_title：Allergy

authors： Mullol J,Bousquet J,Bachert C,Canonica WG,Gimenez-Arnau A,Kowalski ML,Martí-Guadaño E,Maurer M,Picado C,Scadding G,Van Cauwenberge P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Hippo-Yes-associated protein (YAP) pathway plays an important role in epithelial cell proliferation and development. However, its possible role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unknown. We aim to investigate it on nasal epithelial proliferation and remodeling in CRSwNP. METHODS:T...

journal_title：Allergy

authors： Deng H,Sun Y,Wang W,Li M,Yuan T,Kong W,Huang X,Long Z,Chen Z,Wang D,Yang Q

更新日期：2019-04-01 00:00:00

abstract：:Anaphylaxis is a systemic allergic reaction, potentially life-threatening that can be due to nonoccupational or, less commonly, to occupational triggers. Occupational anaphylaxis (OcAn) could be defined as anaphylaxis arising out of triggers and conditions attributable to a particular work environment. Hymenoptera sti...

journal_title：Allergy

authors： Siracusa A,Folletti I,Gerth van Wijk R,Jeebhay MF,Moscato G,Quirce S,Raulf M,Ruëff F,Walusiak-Skorupa J,Whitaker P,Tarlo SM

更新日期：2015-02-01 00:00:00

abstract：:In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...

journal_title：Allergy

authors： Dorsch W,Ring J

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Outside clinical trials, data on systemic reactions (SRs) due to allergen immunotherapy (AIT) are scarce. METHODS:A prospective, longitudinal, web-based survey of 'real-life' respiratory allergen immunotherapy (AIT) clinical practice was conducted in France, Germany and Spain. SRs were recorded and coded ac...

journal_title：Allergy

authors： Calderón MA,Vidal C,Rodríguez Del Río P,Just J,Pfaar O,Tabar AI,Sánchez-Machín I,Bubel P,Borja J,Eberle P,Reiber R,Bouvier M,Lepelliez A,Klimek L,Demoly P,EASSI Doctors' Group.

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：:A total of 109 subjects reporting symptoms indicating type I hypersensitivity reactions to natural rubber latex (NRL) gloves was included in this study, and 66 of them had latex-specific IgE antibodies. They underwent provocation tests by wearing two types of NRL gloves with high (n=103) and low (n=75) allergen conten...

journal_title：Allergy

authors： Baur X,Chen Z,Allmers H,Raulf-Heimsoth M

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Venom immunotherapy (VIT) is regarded as an established and efficient treatment of Hymenoptera venom allergy. Different frequencies of side-effects have been reported in the literature, depending on the hyposensitization regimen (conventional outpatient programme, rush immunotherapy, ultra rush immunotherapy...

journal_title：Allergy

authors： Wenzel J,Meissner-Kraemer M,Bauer R,Bieber T,Gerdsen R

更新日期：2003-11-01 00:00:00

abstract：:This study investigated the relationship between the specific immunoglobulin E (IgE) profile for 40 allergens using a novel microarray technique (BioIC) and fraction of exhaled nitric oxide (FeNO) in a population sample of 1321 children. Significant positive associations were found between FeNO and sensitization to mi...

journal_title：Allergy

authors： Yao TC,Tsai HJ,Tu YL,Chang SW,Hua MC,Liao SL,Tsai MH,Chiu CY,Lai SH,Yeh KW,Huang JL,PATCH study group.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Bronchial, nasal, and conjunctival challenges are useful for clarifying discordant clinical history (Hx) and skin and/or serologic tests and in assessing semiquantitative changes in biologic sensitivity over time. The objective of this study was to determine the safety and reproducibility of repeated latex-a...

journal_title：Allergy

authors： Kurtz KM,Hamilton RG,Schaefer JA,Primeau MN,Adkinson NF Jr

更新日期：2001-09-01 00:00:00

abstract：:Several observations have indicated that house-dust mites (HDM) play an important role in allergic diseases. Thus, the primary form of treatment should aim at reducing exposure to HDM for these patients. Allergen-avoidance measures in homes have been demonstrated to be beneficial in decreasing the risk of sensitizatio...

journal_title：Allergy

authors： Kalpaklioğlu AF,Ferizli AG,Misirligil Z,Demirel YS,Gürbüz L

更新日期：1996-03-01 00:00:00

abstract：:Children with recurrent lower respiratory tract infection (RLRI) may respond poorly to polysaccharide antigens. To examine how such children respond to a polysaccharide coupled to a protein carrier, we immunized 15 children with RLRI aged 8-69 months and 15 carefully age-matched healthy controls once with a Haemophilu...

journal_title：Allergy

authors： Kristensen K,Barington T,Pressler T,Heilmann C

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Endogenous histamine-releasing factors (HRFs) are involved in 30-60% of patients with chronic urticaria (CU). Evidence for their existence comes from in vivo studies of autoreactivity with the autologous serum skin test (ASST), in vitro immunoassays demonstrating autoantibodies against the immunoglobulin E (...

journal_title：Allergy

authors： Platzer MH,Grattan CE,Poulsen LK,Skov PS

更新日期：2005-09-01 00:00:00

abstract：:The prevalence of chronic immune and metabolic disorders is increasing rapidly. In particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive pulmonary disease have become major healthcare and economic burdens worldwide. Recent advances in microbiome research have led to significant dis...

journal_title：Allergy

authors： Alemao CA,Budden KF,Gomez HM,Rehman SF,Marshall JE,Shukla SD,Donovan C,Forster SC,Yang IA,Keely S,Mann ER,El Omar EM,Belz GT,Hansbro PM

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Atopic eczema/dermatitis syndrome (AEDS) patients display immunoglobulin E (IgE) reactivity to several antigens, e.g. saprophytic yeasts as Malassezia furfur. AEDS patients also show IgE autoreactivity towards cells of their own tissue including epidermis. PURPOSE OF THE STUDY:The aim of this study was to i...

journal_title：Allergy

authors： Kortekangas-Savolainen O,Peltonen S,Pummi K,Kalimo K,Savolainen J

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Chronic respiratory diseases (CRD) are greatly underestimated. The aim of this study was to assess the burden associated with reported CRD and chronic obstructive pulmonary disease, as defined on the basis of various standardized criteria, by estimating their point prevalence in a sample of individuals atten...

journal_title：Allergy

authors： Martins P,Rosado-Pinto J,do Céu Teixeira M,Neuparth N,Silva O,Tavares H,Spencer JL,Mascarenhas D,Papoila AL,Khaltaev N,Annesi-Maesano I

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...

journal_title：Allergy

authors： Krause K,Spohr A,Zuberbier T,Church MK,Maurer M

更新日期：2013-07-01 00:00:00

abstract：:Thirty children with rhinoconjunctivitis due to birch pollinosis were treated in a double blind manner for 10 months with enteric-coated capsules containing either a birch pollen preparation (n = 14) with doses up to 1.4 X 10(6) biologic units per day or placebo (n = 16). Compared with the placebo group the actively t...

journal_title：Allergy

authors： Möller C,Dreborg S,Lanner A,Björkstén B

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:There is strong evidence that reduced exposures to microbial compounds triggering innate immune responses early in life are critical for the development of allergic illnesses. The underlying mechanisms remain unknown, but will include T-cell responses either along T helper type 1 (Th1)/Th2 pathways or via T ...

journal_title：Allergy

authors： Schaub B,Liu J,Schleich I,Höppler S,Sattler C,von Mutius E

更新日期：2008-11-01 00:00:00

abstract：:Inbred guinea pigs selected for high (IMM/S) respectively low (IMM/R) responsiveness to ovalbumin (OA) as measured by induced respiratory anaphylaxis, were investigated for atopic immune responses of their conjunctival mucosa. IMM/S animals sensitized either by inhalation of OA, or by instillation of antigen into the ...

journal_title：Allergy

authors： Lundberg L,Bertelsen C,Zavaro A,Samra Z,Sompolinsky D

更新日期：1987-05-01 00:00:00

abstract：:Mast cell activation (MCA) occurs in a number of different clinical conditions, including IgE-dependent allergies, other inflammatory reactions, and mastocytosis. MCA-related symptoms may be mild, moderate, severe, or even life-threatening. The severity of MCA depends on a number of different factors, including geneti...

journal_title：Allergy

authors： Valent P

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed. METHODS:In 18 CRS patients without nasal polyps (CRSNP(-)), 35 CRSNP(+) patients and 22 patients with nasal structural abnormalities w...

journal_title：Allergy

authors： Kirsche H,Niederführ A,Deutschle T,Fuchs C,Riechelmann H

更新日期：2010-01-01 00:00:00

abstract：:Azelastine hydrochloride, chemically known as 1(2H)-phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepine-4-yl)-, monohydrochloride, is a novel, orally effective, long-acting, antiallergic/antiasthmatic agent. The ability of azelastine and selected antiallergic drugs to inhibit SRS-A (leukotriene)...

journal_title：Allergy

authors： Chand N,Nolan K,Diamantis W,Perhach JL Jr,Sofia RD

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Aluminium (ALUM) is used as experimental and clinical adjuvant for parenteral vaccine formulation. It is also contained in anti-acid drugs like sucralfate (SUC). These anti-acids have been shown to cause sensitization to food proteins via elevation of the gastric pH. The aim of this study was to assess the o...

journal_title：Allergy

authors： Brunner R,Wallmann J,Szalai K,Karagiannis P,Altmeppen H,Riemer AB,Jensen-Jarolim E,Pali-Schöll I

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:IL-33 enhances FcεRI-induced mediator release in human basophils without inducing degranulation itself. In contrast, studies in mice suggested that in the presence of high IgE levels, IL-33 triggers degranulation and anaphylaxis of similar severity as specific allergen. Consistent with this view, sera of ato...

journal_title：Allergy

authors： Fux M,Pecaric-Petkovic T,Odermatt A,Hausmann OV,Lorentz A,Bischoff SC,Virchow JC,Dahinden CA

更新日期：2014-02-01 00:00:00

abstract：:In 77 consecutive patients with grass pollen rhinitis as the only allergic disease, treatment with sodium cromoglycate (SCG) nasal spray, hyposensitization with aluminium hydroxide adsorbed extract of grass pollen as perennial treatment, and a combination of the two was compared. Specific serum-IgE, IgG and IgG4 were ...

journal_title：Allergy

authors： Andersen NH,Jeppesen F,Schiøler T,Osterballe O

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Recent studies showed the presence of a unique dust-mite fauna in the indoor environment of Singapore. Immediate hypersensitivity to these dust mites, along with other known indoor allergens, may play a role in the pathogenesis of allergic respiratory diseases. This study evaluated the sensitization rates of...

journal_title：Allergy

authors： Chew FT,Lim SH,Goh DY,Lee BW

更新日期：1999-11-01 00:00:00