Abstract:
:The aim of the study was to investigate whether topical application of a beta-2-adrenostimulant (fenoterol) on the mucous membrane has a clinically significant anti-allergic effect. Thirty-three patients with grass pollen hay fever completed the trial which was a double-blind, placebo-controlled cross-over design. After a run-in period the patients received two puffs of 50 micrograms fenoterol 4 times a day or placebo for 21/2 weeks before cross-over. Symptoms were scored on diary cards and there was a moderate, but significant effect of fenoterol on sneezing, but the effect on secretion and blockage was insignificant. It is concluded that beta-2-stimulating agents are not competitors to the very effective topical steroids.
journal_name
Allergyjournal_title
Allergyauthors
Borum P,Larsen FSdoi
10.1111/j.1398-9995.1987.tb02372.xsubject
Has Abstractpub_date
1987-02-01 00:00:00pages
141-5issue
2eissn
0105-4538issn
1398-9995journal_volume
42pub_type
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