Influence of hyposensitization on soluble interleukin-2 receptor, eosinophil cationic protein, in vitro lymphocyte proliferation, in vitro lymphocyte adhesion, and lymphocyte membrane markers in childhood asthma.

abstract：:PVG rats given injections of 1 microgram ovalbumin (OA) together with 10 mg Silica gel failed to provide serosal mast cells or lung tissue with the capacity to release histamine on in vitro challenge with the antigen. However, if such animals were injected i.p. with 100 mg of alum (without any further antigen addition...

journal_title：Allergy

authors： Bergstrand H,Andersson I,Nyström I,Pauwels R,Bazin H

更新日期：1983-05-01 00:00:00

abstract：:Recent advances in experimental immunologic approaches to seasonal allergic rhinitis (SAR) have led to a shift in the concepts of its pathogenesis. The conventional view of SAR as a local response to inhaled allergens has largely given way to a new view of this disorder as a systemic condition with local tissue manife...

journal_title：Allergy

authors： Bachert C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In a previous controlled study we demonstrated that preseasonal grass pollen immunotherapy for three years was effective in children. In the current study we examined the same group of patients to see if there is still a benefit six years after discontinuation of treatment. METHODS:Thirteen of 14 patients w...

journal_title：Allergy

authors： Eng PA,Reinhold M,Gnehm HP

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Exposure to acrylates may give rise to rhinitis and asthma in both industrial and domestic environments. The mechanisms underlying these respiratory conditions caused by acrylates remain largely unknown. METHODS:We studied two assembly operators exposed to cyanoacrylate glue who developed rhinitis and asthm...

journal_title：Allergy

authors： Quirce S,Baeza ML,Tornero P,Blasco A,Barranco R,Sastre J

更新日期：2001-05-01 00:00:00

abstract：:Five biologicals have been approved for severe eosinophilic asthma, a well-recognized phenotype. Systematic reviews (SR) evaluated the efficacy and safety of benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab (alphabetical order) compared to standard of care for severe eosinophilic asthma. PubMed, Embase ...

journal_title：Allergy

authors： Agache I,Beltran J,Akdis C,Akdis M,Canelo-Aybar C,Canonica GW,Casale T,Chivato T,Corren J,Del Giacco S,Eiwegger T,Firinu D,Gern JE,Hamelmann E,Hanania N,Mäkelä M,Hernández-Martín I,Nair P,O'Mahony L,Papadopoulos NG

更新日期：2020-05-01 00:00:00

abstract：:During the last few years, an impressive amount of experimental studies and clinical trials have dealt with a variety of distinct topics in allergic skin diseases - especially atopic dermatitis. In this update, we discuss selected recent data that provide relevant insights into clinical and pathophysiological aspects ...

journal_title：Allergy

authors： Wollenberg A,Feichtner K

更新日期：2013-12-01 00:00:00

abstract：:Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the approach to patients with allergic diseases encompasses novel developments in the area of personalized medicine, disease phenotyping and endotyping, and the develo...

journal_title：Allergy

authors： Breiteneder H,Peng YQ,Agache I,Diamant Z,Eiwegger T,Fokkens WJ,Traidl-Hoffmann C,Nadeau K,O'Hehir RE,O'Mahony L,Pfaar O,Torres MJ,Wang DY,Zhang L,Akdis CA

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:Efficacy testing of immunotherapy in field studies is often hampered by variation of airborne allergens. Standardized allergen exposure in challenge chamber settings might be an alternative. Therefore, we developed a universal technique to create an atmosphere loaded with allergen particles of adjustable siz...

journal_title：Allergy

authors： Lueer K,Biller H,Casper A,Windt H,Mueller M,Badorrek P,Haefner D,Framke T,Koch A,Ziehr H,Krug N,Koch W,Hohlfeld JM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is high, there is currently no specific and validated instrument to...

journal_title：Allergy

authors： Siebenhaar F,Sander B,Ho LHT,Ellrich A,Maurer M,Weller K

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire. METHODS:To validate questions used in a country-wide study among university students aged 18-25 year...

journal_title：Allergy

authors： Kilpeläinen M,Terho EO,Helenius H,Koskenvuo M

更新日期：2001-05-01 00:00:00

abstract：:An atopic girl experienced an anaphylactic reaction after eating cookies containing pecan nuts. Investigations revealed that she had developed IgE antibodies exclusively specific against allergenic determinants present in aged or heated pecan nuts, but not in fresh pecans. These neoallergenic determinants were located...

journal_title：Allergy

authors： Malanin K,Lundberg M,Johansson SG

更新日期：1995-12-01 00:00:00

abstract：:This update aimed to review the new evidence available to support or refute prior Allergic Rhinitis and its Impact on Asthma (ARIA) statements. A Medline search of publications between 2000 and 2005 was conducted, with articles selected by experts. New evidence supports previous ARIA statements, such as: (i) allergic ...

journal_title：Allergy

authors： Cruz AA,Popov T,Pawankar R,Annesi-Maesano I,Fokkens W,Kemp J,Ohta K,Price D,Bousquet J,ARIA Initiative Scientific Committee.

更新日期：2007-01-01 00:00:00

abstract：:The clinical effects in asthma of corticosteroids can be ascribed to their strong anti-inflammatory action. The pathophysiology of asthma is complex. A diversity of mediators and interactions between mediators and between mediators and various cell types enhances and maintains the inflammatory process in the airways r...

journal_title：Allergy

authors： Norn S,Clementsen P

更新日期：1988-08-01 00:00:00

abstract：:This study investigated the relationship between the specific immunoglobulin E (IgE) profile for 40 allergens using a novel microarray technique (BioIC) and fraction of exhaled nitric oxide (FeNO) in a population sample of 1321 children. Significant positive associations were found between FeNO and sensitization to mi...

journal_title：Allergy

authors： Yao TC,Tsai HJ,Tu YL,Chang SW,Hua MC,Liao SL,Tsai MH,Chiu CY,Lai SH,Yeh KW,Huang JL,PATCH study group.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：:In immunotherapy of grass pollen allergy, an extract of rye (Secale cereale) is often included. The aim of this study was to investigate by skin prick test (SPT) and immunochemical methods whether rye pollen contains specific allergens justifying the use of this extract separately. Twenty grass pollen allergic patient...

journal_title：Allergy

authors： Løwenstein H,Wihl JA,Bache Billesbølle K,Bøwadt H

更新日期：1984-08-01 00:00:00

abstract：:In recent years, significant attention has been paid to the use of biotechnology to improve the quality and quantity of the food supply due in part to the projected growth in the world population, plus limited options available for increasing the amount of land under cultivation. Alterations in the food supply induced...

journal_title：Allergy

authors： Lehrer SB,Bannon GA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Alkaline serine proteases from six prevalent airborne Penicillium and Aspergillus species have been identified as a group of major allergens (group 13). After entering human airways, the allergens are in initial contacts with respiratory epithelial cells. The purpose of this study is to investigate interacti...

journal_title：Allergy

authors： Tai HY,Tam MF,Chou H,Peng HJ,Su SN,Perng DW,Shen HD

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Previous observational studies have implied breastmilk fatty acid composition may play a role in the development of atopic eczema or atopic sensitization in breastfed infants and toddlers. However, studies investigating associations with wheeze and asthma in later childhood are scarce and did not account for...

journal_title：Allergy

authors： Logan CA,Brandt S,Wabitsch M,Brenner H,Wiens F,Stahl B,Marosvölgyi T,Decsi T,Rothenbacher D,Genuneit J

更新日期：2017-09-01 00:00:00

abstract：:Pityrosporum orbiculare and Candida albicans extracts were separated by SDS-PAGE, and IgE binding was detected by immunoblotting with 21 patient sera that were RAST positive to both yeasts. Cross-wise inhibition was performed of IgE binding of a serum pool containing IgE antibodies to both yeasts. The pool was mixed w...

journal_title：Allergy

authors： Huang X,Johansson SG,Zargari A,Nordvall SL

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Pollutants may affect pollen allergenicity and thus the prevalence of allergies. Although a few studies are available in literature, the connection between pollution and the allergenic potential of pollen has yet to be clearly defined. The objective of this study was to evaluate the effect of traffic-related...

journal_title：Allergy

authors： Ghiani A,Aina R,Asero R,Bellotto E,Citterio S

更新日期：2012-07-01 00:00:00

abstract：:Because humans breathe through the nose, the nasal mucosa becomes sensitized to inhalant allergens. Allergic rhinitis is, together with allergic conjunctivitis, the best example of a type I hypersensitivity reaction. It is an inflammation of the nasal mucosa induced by specific immune recognition of exogenous allergen...

journal_title：Allergy

authors： Van Cauwenberge PB

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Patients with nonallergic asthma frequently show autoreactivity as do subjects with chronic urticaria (CU). Activation of the coagulation cascade and hyper-expression of vascular endothelial growth factor (VEGF) were recently found in CU, and there is sparse evidence that the same may occur in asthma. OBJEC...

journal_title：Allergy

authors： Asero R,Tedeschi A,Cugno M

更新日期：2011-10-01 00:00:00

abstract：:Several observations have indicated that house-dust mites (HDM) play an important role in allergic diseases. Thus, the primary form of treatment should aim at reducing exposure to HDM for these patients. Allergen-avoidance measures in homes have been demonstrated to be beneficial in decreasing the risk of sensitizatio...

journal_title：Allergy

authors： Kalpaklioğlu AF,Ferizli AG,Misirligil Z,Demirel YS,Gürbüz L

更新日期：1996-03-01 00:00:00

abstract：:Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

journal_title：Allergy

authors： Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Occupational allergy forms an attractive model to study the development of allergic responses, as in some occupations it has a high incidence and develops quickly. In a cohort of starting laboratory animal workers, we previously found 20% sensitization to animal allergens within 2 years. METHODS:We compared...

journal_title：Allergy

authors： Krop EJ,van de Pol MA,Lutter R,Heederik DJ,Aalberse RC,van der Zee JS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Allergic asthma is associated with airway inflammation and dysfunction of pulmonary surfactant. Because surfactant proteins (SP) account for immunomodulatory functions as well as biophysical functions, we hypothesized that the allergic response in asthma might be accompanied by a dysregulation of SPs. METHO...

journal_title：Allergy

authors： Erpenbeck VJ,Schmidt R,Günther A,Krug N,Hohlfeld JM

更新日期：2006-05-01 00:00:00

abstract：:: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

journal_title：Allergy

authors： Sørensen P

更新日期：2011-07-01 00:00:00

abstract：:Intramuscular adrenaline is the gold standard treatment for anaphylaxis. Intramuscular injection provides more rapid and higher plasma concentrations than subcutaneous routes. Given the increasing epidemic of obesity patients are at increased risk of subcutaneous delivery, we therefore assessed the depth of subcutaneo...

journal_title：Allergy

authors： Johnstone J,Hobbins S,Parekh D,O'Hickey S

更新日期：2015-06-01 00:00:00