ILC2 frequency and activity are inhibited by glucocorticoid treatment via STAT pathway in patients with asthma.

abstract：:Although copper sulfate can cause systemic contact dermatitis, few such cases have been recorded among copper-releasing IUD users. Reported in this paper is a case of endometritis and urticaria-angioedema syndrome in a 32-year-old user of a copper IUD. Widespread urticaria, as well as angioedema of the eyelids and t...

journal_title：Allergy

authors： Purello D'Ambrosio F,Ricciardi L,Isola S,Gangemi S,Cilia M,Levanti C,Marcazzò A

更新日期：1996-09-01 00:00:00

abstract：:Overproduction of periostin, an IL-13-inducible matricellular protein, despite corticosteroid treatment is thought to be involved in the chronicity of allergic inflammation seen in corticosteroid-refractory tissue fibrosis. Therefore, we hypothesized that some tissue cells must produce periostin in a corticosteroid-in...

journal_title：Allergy

authors： Shoda T,Futamura K,Kobayashi F,Saito H,Matsumoto K,Matsuda A

更新日期：2013-11-01 00:00:00

abstract：:In a study conducted 1 year ago, we found that Th1 immune enhancement following Bacille Calmette-Guérin (BCG) vaccination effectively suppressed human asthma. To investigate whether revaccination would further improve lung function, BCG vaccine was given again. Current lung function tended to improve in the Repeated B...

journal_title：Allergy

authors： Choi IS,Koh YI

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a multifactorial and probably multigenic inflammatory disease of the upper airways, and has been associated with the HLA class II alleles DR4 and DR7. Here we investigated possible associations with other polymorphic susceptibility/resistance genes located within the major histocompatibili...

journal_title：Allergy

authors： Aron Y,Busson M,Polla BS,Dusser D,Lockhart A,Swierczewski E,Favatier F

更新日期：1999-02-01 00:00:00

abstract：:A 17-year-old man was occupationally exposed to pyromellitic acid dianhydride dust during the production of epoxy resin in a chemical factory. He was clinically diagnosed as having acute hemorrhagic alveolitis associated with anemia. The serologic analysis revealed a high concentration of IgG antibodies against pyrome...

journal_title：Allergy

authors： Czuppon AB,Kaplan V,Speich R,Baur X

更新日期：1994-05-01 00:00:00

abstract：:The prevalence and specificity of naturally occurring human IgA anti-IgE autoantibodies (a-E Ab) were studied by ELISA with anti-IgA monoclonal antibodies (mAb) and a purified myeloma IgE as solid-phase protein, i.e., IgE-DES(kappa). Such detected IgA a-E Ab were common among adults, and significantly increased geomet...

journal_title：Allergy

authors： Magnusson CG

更新日期：1994-12-01 00:00:00

abstract：:The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

journal_title：Allergy

authors： Wüthrich B

更新日期：1998-01-01 00:00:00

abstract：:The diagnosis of food IgE-dependent hypersensitivity is based on the demonstration of specific IgE, completed by provocation tests. Two immunoenzymatic techniques, the Phadezym and the FAST, are compared with the Phadebas RAST, in 86 sera (23 controls, 28 from patients with a reported food allergy and 35 with a positi...

journal_title：Allergy

authors： Moneret-Vautrin DA,Gueant JL,Abdel-Ghani A,Maria Y,Nicolas JP

更新日期：1990-02-01 00:00:00

abstract：:Fourteen adults and 10 children with active atopic dermatitis entered this double blind cross-over study of oral disodium cromoglycate (DSCG) (adults 200 mg qid, children 100 mg qid) compared with placebo. Oral DSCG and placebo were given for 6 weeks in random order. According to the investigators' assessments of ecze...

journal_title：Allergy

authors： Lindskov R,Knudsen L

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Exposure to environmental endocrine-disrupting chemicals (EDCs) is associated with allergy, chronic inflammation, and immunodeficiency. Phthalates, the common EDCs used in plastic industry, may act as adjuvants to disrupt immune system and enhance allergy. Plasmacytoid DCs (pDCs) are predominant cells secret...

journal_title：Allergy

authors： Kuo CH,Hsieh CC,Kuo HF,Huang MY,Yang SN,Chen LC,Huang SK,Hung CH

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Undernotification is well recognized as a key challenge to the study of anaphylaxis mortality, but it is seldom mentioned that one of its reasons is the difficult coding of the condition under the tenth revision of the international classification of diseases (ICD-10), given that there are no anaphylaxis-spe...

journal_title：Allergy

authors： Tanno LK,Ganem F,Demoly P,Toscano CM,Bierrenbach AL

更新日期：2012-06-01 00:00:00

abstract：:In studies on atopic dermatitis (AD), different scoring systems are used to evaluate the severity of the disease. The objective of this study was to investigate agreement between observers in the assessment of the overall severity of AD, and interobserver variation in the assessment of severity of AD for each scoring ...

journal_title：Allergy

authors： Sprikkelman AB,Tupker RA,Burgerhof H,Schouten JP,Brand PL,Heymans HS,van Aalderen WM

更新日期：1997-09-01 00:00:00

abstract：:In a study of 770 patients with allergic rhinitis, anamnestic data were collected by means of a questionnaire. 484 (63%) of the patients were women and 286 (37%) men. 45.5% of the patients had perennial symptoms, 33.5% had seasonal symptoms only, and 21% had predominantly seasonal but also some perennial symptoms. Mor...

journal_title：Allergy

authors： Binder E,Holopainen E,Malmberg H,Salo O

更新日期：1982-08-01 00:00:00

abstract：:To determine optimal conditions for allergen preservation, we investigated the influence of different stabilizing additives and of storage temperature on the allergen activity of apple protein preparations, obtained by extraction in phosphate buffer or by precipitation in diacetone alcohol and resolubilization in phos...

journal_title：Allergy

authors： Rudeschko O,Fahlbusch B,Henzgen M,Schlenvoigt G,Herrmann D,Vieths S,Jäger L

更新日期：1995-07-01 00:00:00

abstract：:Dose- and pH- dependent carbodiimide-mediated coupling of Penicillin-G to polystyrene microtiter-plates that leaves the beta-lactam ring unchanged is described. A new ELISA method was developed using Penicillin-G coated plates. The binding of 3 different monoclonal antibodies as well as human IgG antibodies of the IgG...

journal_title：Allergy

authors： Klein GF,Stanzl U,Fritsch PO,Varga JM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Measurement of exposure to the dust mite allergen Der p 1 is important in asthma research and is potentially useful in managing asthma. As no single measure can capture all characteristics of an exposure, it is important to recognize differences in the available methods of measuring exposure to Der p 1. MET...

journal_title：Allergy

authors： Tovey ER,Mitakakis TZ,Sercombe JK,Vanlaar CH,Marks GB

更新日期：2003-08-01 00:00:00

abstract：:Ispaghula powder, which is used as a component in bulk laxatives, is known to induce allergic reactions when inhaled by occupationally exposed persons. We have tested whether nurses sensitized by inhalation could get allergic symptoms when challenged by eating ispaghula. Of six nurses tested, all developed symptoms fr...

journal_title：Allergy

authors： Machado L,Stålenheim G

更新日期：1984-01-01 00:00:00

abstract：:Exposure to house-dust-mite allergens is an important cause of allergic reactions in sensitized patients. In community-based studies, sensitization to house-dust mites, as ascertained by a positive skin test or by an increased allergen-specific IgE level in serum, is associated with both diminished lung function and e...

journal_title：Allergy

authors： van der Heide S,Dubois AE,Kauffman HF,de Monchy JG

更新日期：1998-01-01 00:00:00

abstract：:The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...

journal_title：Allergy

authors： Odelram H,Björkstén B,Chan SC,Hanifin JM,Kjellman NI

更新日期：1994-09-01 00:00:00

abstract：:We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation b...

journal_title：Allergy

authors： Apostolovic D,Sánchez-Vidaurre S,Waden K,Curin M,Grundström J,Gafvelin G,Cirkovic Velickovic T,Grönlund H,Thomas WR,Valenta R,Hamsten C,van Hage M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In this study, we examined T cell responses and HLA class II alleles in children with moderate-severe asthma. METHODS:Ninety-six children with moderate-severe asthma w...

journal_title：Allergy

authors： Knutsen AP,Vijay HM,Kumar V,Kariuki B,Santiago LA,Graff R,Wofford JD,Shah MR

更新日期：2010-11-01 00:00:00

abstract：:Regulatory approaches for allergen immunotherapy (AIT) products and the availability of high-quality AIT products are inherently linked to each other. While allergen products are available in many countries across the globe, their regulation is very heterogeneous. First, we describe the regulatory systems applicable f...

journal_title：Allergy

authors： Bonertz A,Roberts GC,Hoefnagel M,Timon M,Slater JE,Rabin RL,Bridgewater J,Pini C,Pfaar O,Akdis C,Goldstein J,Poulsen LK,van Ree R,Rhyner C,Barber D,Palomares O,Sheikh A,Pawankar R,Hamerlijnk D,Klimek L,Agache I,

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti-microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airways disease are reflected by the γProteobacteria:Firmicutes (γP:F) ratio....

journal_title：Allergy

authors： Diver S,Richardson M,Haldar K,Ghebre MA,Ramsheh MY,Bafadhel M,Desai D,Cohen ES,Newbold P,Rapley L,Rugman P,Pavord ID,May RD,Barer M,Brightling CE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Fel d 1 is the major cat allergen, inducing asthma in sensitized individuals. It is produced by the skin and lies on fur. Recently, it was established that the amount of Fel d 1 on fur varies among anatomical sites. However, it is not known whether the allergen production by skin varies in parallel. The obje...

journal_title：Allergy

authors： Carayol N,Birnbaum J,Magnan A,Ramadour M,Lanteaume A,Vervloet D,Tessier Y,Pageat P

更新日期：2000-06-01 00:00:00

abstract：:Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of variable severity, which share a common complication of reversible airflow obstruction. Asthma is estimated to affect almost 400 million people worldwide, and nearly ten percent of asthmatics have what is considered "severe" disea...

journal_title：Allergy

authors： Perkins TN,Donnell ML,Oury TD

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND:Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS:In two population-based birth cohorts (Manchester and Isle of Wig...

journal_title：Allergy

authors： Lazic N,Roberts G,Custovic A,Belgrave D,Bishop CM,Winn J,Curtin JA,Hasan Arshad S,Simpson A

更新日期：2013-06-01 00:00:00

abstract：:The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line of defense. Apart from the well-described physical barrier and the mucociliary clearance, a variety of systems, including the airway microbiome, antimicrobial pr...

journal_title：Allergy

authors： Zhang N,Van Crombruggen K,Gevaert E,Bachert C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Sequential human herpes virus (HHV) reactivation is well known in drug reaction with eosinophilia and systemic symptom (DRESS), but such a phenomenon has seldom studied in other types of cutaneous adverse drug reactions (cADRs). Moreover, the association between viral reactivations and cytokine or chemokine ...

journal_title：Allergy

authors： Chen YC,Chiang HH,Cho YT,Chang CY,Chen KL,Yang CW,Lee YH,Chu CY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:As in vitro diagnosis of wasp venom sensitization by specific serum IgE has a sensitivity of only 60-80%, additional in vitro tests are desirable. Basophil activation is associated with the expression of CD63 and its measurement has been proposed as a novel in vitro test for immediate-type allergy. Furthermo...

journal_title：Allergy

authors： Erdmann SM,Sachs B,Kwiecien R,Moll-Slodowy S,Sauer I,Merk HF

更新日期：2004-10-01 00:00:00

abstract：:Delayed-type, T cell-mediated, drug hypersensitivity reactions are a serious unwanted manifestation of drug exposure that develops in a small percentage of the human population. Drugs and drug metabolites are known to interact directly and indirectly (through irreversible protein binding and processing to the derived ...

journal_title：Allergy

authors： Naisbitt DJ,Olsson-Brown A,Gibson A,Meng X,Ogese MO,Tailor A,Thomson P

更新日期：2020-04-01 00:00:00