GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice.

abstract：:The care of patients with difficult-to-control asthma ("difficult asthma") is challenging and costly. Despite high-intensity asthma treatment, these patients experience poor asthma control and face the greatest risk of asthma morbidity and mortality. Poor asthma control is often driven by severe asthma biology, which ...

journal_title：Allergy

authors： Tay TR,Hew M

更新日期：2018-07-01 00:00:00

abstract：:A one-day intensive educational course on allergy and immunology theory and diagnostic procedure significantly increased the competency of allergy and immunology fellows-in-training. ...

journal_title：Allergy

authors： Elizalde A,Perez EE,Sriaroon P,Nguyen D,Lockey RF,Dorsey MJ

更新日期：2012-09-01 00:00:00

abstract：:The relation between platelet counts (PCT) and IgE was studied in cord blood from 136 European newborns. PCT was significantly lower (P = 0.0014) when cord-IgE was superior to 1.20 IU/ml (n = 29; 245,000/microliter) than when it was inferior to this value (n = 107; 284,080/microliter) which resulted in a significant n...

journal_title：Allergy

authors： Magnusson CG,de Weck AL

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:The mechanisms of late asthmatic reactions provoked in atopic asthmatics by allergen-derived T-cell peptide epitopes remain unclear. Previous studies showed no changes in airway eosinophils or mast cell products after peptide challenge. In the present study our aim was to measure calcitonin gene-related pept...

journal_title：Allergy

authors： Kay AB,Ali FR,Heaney LG,Benyahia F,Soh CP,Renz H,Lee TH,Larché M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Health-related quality of Life in patients with chronic urticaria is evaluated by mean of generic instruments or questionnaire designed for skin diseases. No disease-specific tool is now available for the assessment of chronic urticaria impact from patients' viewpoint. OBJECTIVE:The aim of our study is to d...

journal_title：Allergy

authors： Baiardini I,Pasquali M,Braido F,Fumagalli F,Guerra L,Compalati E,Braga M,Lombardi C,Fassio O,Canonica GW

更新日期：2005-08-01 00:00:00

abstract：:B cells are essentially described for their capacity to produce antibodies ensuring anti-infectious immunity or deleterious responses in the case of autoimmunity or allergy. However, abundant data described their ability to restrain inflammation by diverse mechanisms. In allergy, some regulatory B-cell subsets produci...

journal_title：Allergy

authors： Braza F,Chesne J,Castagnet S,Magnan A,Brouard S

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Recombinant allergens offer a tool for improving specific immunotherapy (SIT). OBJECTIVE:To find the optimal dose of a new hypoallergenic folding variant of recombinant Bet v 1 (rBet v 1-FV) as SIT for patients with birch pollen allergy. METHODS:Before SIT, thirty-seven adult patients were exposed for eigh...

journal_title：Allergy

authors： Meyer W,Narkus A,Salapatek AM,Häfner D

更新日期：2013-06-01 00:00:00

abstract：:A family of widely expressed ORM-like (ORMDL) proteins has been recently linked to asthma in genomewide association studies in humans and extensively explored in in vivo studies in mice. ORMDL proteins are key regulators of serine palmitoyltransferase, an enzyme catalyzing the initial step of sphingolipid biosynthesis...

journal_title：Allergy

authors： Paulenda T,Draber P

更新日期：2016-07-01 00:00:00

abstract：:This is a description of the Study of Asthma, Genes and the Environment (SAGE), a novel birth cohort created from provincial healthcare administrative records. It is a general population-based cohort, composed of children at high and low risk for asthma, living in urban and rural environments in Manitoba, Canada. The ...

journal_title：Allergy

authors： Kozyrskyj AL,HayGlass KT,Sandford AJ,Paré PD,Chan-Yeung M,Becker AB

更新日期：2009-08-01 00:00:00

abstract：:Occupational respiratory allergy to green coffee beans in coffee roastery workers is well established. I now report on a 50-year-old female atopic patient sensitized to the coffee plant used for indoor decoration. The symptoms were rhinitis and conjunctivitis on exposure to the plant. Investigation showed a positive s...

journal_title：Allergy

authors： Axelsson IG

更新日期：1994-12-01 00:00:00

abstract：:The effect of heat on the allergenicity of beef and bovine serum albumin was investigated among 10 toddlers skin prick test (SPT)-positive to raw and cooked beef. The meat-allergy diagnosis was confirmed during double-blind, placebo-controlled food challenge (DBPCFC) with 180 g of beef cooked for 5 min at 100 degrees ...

journal_title：Allergy

authors： Fiocchi A,Restani P,Riva E,Mirri GP,Santini I,Bernardo L,Galli CL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the influence of patient selection criteria, i.e., mite-allergic individuals exposed and not exposed to Dermatophagoides siboney and Blomia tropicalis, on the biologic activity of mite extracts. Determination of the potency of mite extracts in vivo requires selection of patien...

journal_title：Allergy

authors： Casas R,Ferrándiz R,Wihl JA,Fernández B,Dreborg S

更新日期：1999-04-01 00:00:00

abstract：:The aim of the study was to develop and evaluate different methods of double-blind, placebo-controlled food challenge (DBPCFC) with apple. Three different DBPCFC models were evaluated: fresh apple juice, freshly grated apple, and freeze-dried apple powder. All challenges were performed outside the pollen season and to...

journal_title：Allergy

authors： Skamstrup Hansen K,Vestergaard H,Stahl Skov P,Søndergaard Khinchi M,Vieths S,Poulsen LK,Bindslev-Jensen C

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Associations between vitamin D status and childhood asthma are increasingly reported, but direct causation and mechanisms underlying an effect remain unknown. We investigated the effect of early-life vitamin D deficiency on the development of murine neonatal allergic airways disease (AAD). METHODS:In utero ...

journal_title：Allergy

authors： Vasiliou JE,Lui S,Walker SA,Chohan V,Xystrakis E,Bush A,Hawrylowicz CM,Saglani S,Lloyd CM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Allergy diagnosis by determination of allergen-specific IgE is complicated by clinically irrelevant IgE, of which the most prominent example is IgE against cross-reactive carbohydrate determinants (CCDs) that occur on allergens from plants and insects. Therefore, CCDs cause numerous false-positive results. I...

journal_title：Allergy

authors： Holzweber F,Svehla E,Fellner W,Dalik T,Stubler S,Hemmer W,Altmann F

更新日期：2013-10-01 00:00:00

abstract：:: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

journal_title：Allergy

authors： Sørensen P

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause. Indeed, recent evidence indicates that bacteria-derived extracellular vesicles (EV) appear to be an important causative agent of inflammatory diseases. Here, we ...

journal_title：Allergy

authors： Choi EB,Hong SW,Kim DK,Jeon SG,Kim KR,Cho SH,Gho YS,Jee YK,Kim YK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Geographical variations in atopic sensitization in Canada have not been described previously. This study used the standardized protocol of the European Community Respiratory Health Survey-1 (ECRHS-1) to investigate the distribution and predictors of atopic sensitization in six sites across Canada and to comp...

journal_title：Allergy

authors： Chan-Yeung M,Anthonisen NR,Becklake MR,Bowie D,Sonia Buist A,Dimich-Ward H,Ernst P,Sears MR,Siersted HC,Sweet L,Van Til L,Manfreda J

更新日期：2010-11-01 00:00:00

abstract：:Skin tests and estimation of specific IgE-antibodies by the RAST are evaluated as diagnostic procedures in bee sting hypersensitivity with the followiny extracts. (2) With bee venom results of skin tests and RAST correspond in 82%, with bee wholebody extracts in 68%. (3) Both with skin tests and the RAST with bee veno...

journal_title：Allergy

authors： Patrizzi R,Müller U,Yman L,Hoigné R

更新日期：1979-08-01 00:00:00

abstract：:Endocrine disrupters (EDs) are environmental pollutants of industrial or agricultural origin (e.g. herbicides, fungicides, insecticides, industrial chemicals) that may influence health of wildlife and human. Endocrine-disrupting effect is obtained by mimicking the action of the steroid hormones and has been associated...

journal_title：Allergy

authors： Chalubinski M,Kowalski ML

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Partial mattress encasing was found to be effective in reducing exposure to mite allergen in our previous investigation. We aimed to compare the short-term efficacy of partial and complete mattress encasing and to study mite-allergen levels within these mattresses. METHODS:Thirty-one mattresses with high mi...

journal_title：Allergy

authors： Vichyanond P,Uthaisangsook S,Ruangruk S,Malainual N

更新日期：1999-07-01 00:00:00

abstract：:We present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). Monoclonal antibody-based immunoassays were used to quantify Der p 1, Der f 1, Der 2, Lep d 1, and Fel d 1. T...

journal_title：Allergy

authors： Echechipía S,Ventas P,Audícana M,Urrutia I,Gastaminza G,Polo F,Fernández de Corres L

更新日期：1995-06-01 00:00:00

abstract：:Quantitative risk assessment (QRA) for food allergens has made considerable progress in recent years, yet acceptability of its outcomes remains stymied because of the limited extent to which it has been possible to incorporate severity as a variable. Reaction severity, particularly following accidental exposure, depen...

journal_title：Allergy

authors： Dubois AEJ,Turner PJ,Hourihane J,Ballmer-Weber B,Beyer K,Chan CH,Gowland MH,O'Hagan S,Regent L,Remington B,Schnadt S,Stroheker T,Crevel RWR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Daily intensive exercise by elite athletes can result in exercise-induced asthma especially in elite swimmers and this may be linked to epithelial damage. OBJECTIVE:To study airway epithelial damage and release of damage-associated molecular patterns (DAMPs) after intensive exercise in elite athletes and co...

journal_title：Allergy

authors： Seys SF,Hox V,Van Gerven L,Dilissen E,Marijsse G,Peeters E,Dekimpe E,Kasran A,Aertgeerts S,Troosters T,Vanbelle V,Peers K,Ceuppens JL,Hellings PW,Dupont LJ,Bullens DM

更新日期：2015-02-01 00:00:00

abstract：:It is debatable whether beta 2-receptor agonists produce antiallergic effects in human airways. This question has been addressed in the present study by examination of both mast-cell indices and the physiologic response to allergen challenge in human nasal airways. Twelve asymptomatic patients with seasonal allergic r...

journal_title：Allergy

authors： Svensson C,Greiff L,Andersson M,Alkner U,Grönneberg R,Persson CG

更新日期：1995-11-01 00:00:00

abstract：:Identification and characterization of risk and protective factors for allergy is important for developing strategies for prevention or treatment. The prevalence of allergy is clearly higher in affluent countries than in developing countries like, e.g. Africa. Especially in urban areas of developing countries, allergy...

journal_title：Allergy

authors： van Ree R,Yazdanbakhsh M

更新日期：2007-03-01 00:00:00

abstract：:Azelastine hydrochloride, chemically known as 1(2H)-phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepine-4-yl)-, monohydrochloride, is a novel, orally effective, long-acting, antiallergic/antiasthmatic agent. The ability of azelastine and selected antiallergic drugs to inhibit SRS-A (leukotriene)...

journal_title：Allergy

authors： Chand N,Nolan K,Diamantis W,Perhach JL Jr,Sofia RD

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Workplace exposure to trimellitic anhydride (TMA) can elicit TMA-specific IgE (sIgE), which may lead to occupational asthma (OA). An occupational immunosurveillance program (OISP) has been implemented to monitor TMA exposure and immunologic outcomes. The purpose of this study was to determine whether TMA-spe...

journal_title：Allergy

authors： Ghosh D,Clay C,Bernstein JA

更新日期：2018-05-01 00:00:00

abstract：:Group 2 innate lymphoid cells (ILC2s) are a recently identified group of cells with the potent capability to produce Th2-type cytokines such as interleukin (IL)-5 and IL-13. Several studies suggest that ILC2s play an important role in the development of allergic diseases and asthma. Activation of pulmonary ILC2s in mu...

journal_title：Allergy

authors： Aron JL,Akbari O

更新日期：2017-08-01 00:00:00

abstract：:In this study, we investigated the role of calcium and phospholipid-dependent protein kinase (protein kinase C, PKC) in the modulation of histamine release from human basophils. A novel and potent inhibitor of PKC, K-252a, inhibited the release of histamine induced by anti-IgE in a dose-dependent manner with ID50 (the...

journal_title：Allergy

authors： Morita Y,Takaishi T,Honda Z,Miyamoto T

更新日期：1988-02-01 00:00:00